| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2009PLoSO...4.5701S |
| P356 | DOI | 10.1371/JOURNAL.PONE.0005701 |
| P932 | PMC publication ID | 2683574 |
| P698 | PubMed publication ID | 19492085 |
| P5875 | ResearchGate publication ID | 26262617 |
| P50 | author | Alexandra Beilina | Q30112410 |
| Megan M. Cleland | Q37380094 | ||
| Angel Cedazo-Minguez | Q42386403 | ||
| Mark R Cookson | Q67168137 | ||
| David W. Miller | Q118221210 | ||
| P2093 | author name string | Homira Behbahani | |
| Kelly Jean Thomas | |||
| Marcel van der Brug | |||
| Richard F Cowburn | |||
| Anna Sandebring | |||
| Rili Ahmad | |||
| Ibardo Zambrano | |||
| P2860 | cites work | Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability | Q24299939 |
| Biochemical aspects of the neuroprotective mechanism of PTEN-induced kinase-1 (PINK1) | Q24307730 | ||
| PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1 | Q24312106 | ||
| Levels of human Fis1 at the mitochondrial outer membrane regulate mitochondrial morphology | Q24313537 | ||
| Parkin is recruited selectively to impaired mitochondria and promotes their autophagy | Q24317471 | ||
| Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria | Q24320227 | ||
| Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission | Q24320327 | ||
| The kinase domain of mitochondrial PINK1 faces the cytoplasm | Q24321709 | ||
| PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons | Q24322788 | ||
| Hereditary early-onset Parkinson's disease caused by mutations in PINK1 | Q24337084 | ||
| Fission and selective fusion govern mitochondrial segregation and elimination by autophagy | Q24652230 | ||
| Endophilin B1 is required for the maintenance of mitochondrial morphology | Q24678157 | ||
| Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clones | Q28285883 | ||
| Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice | Q28513036 | ||
| Role of Bax and Bak in mitochondrial morphogenesis | Q28591724 | ||
| Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress | Q28592727 | ||
| Mitochondrial dysfunction and oxidative damage in parkin-deficient mice | Q28593859 | ||
| Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin | Q29547423 | ||
| The PINK1/Parkin pathway regulates mitochondrial morphology | Q29615641 | ||
| Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin | Q29615684 | ||
| Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin | Q29617063 | ||
| The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila | Q29617091 | ||
| Mitofusin 2 tethers endoplasmic reticulum to mitochondria | Q29619861 | ||
| Reversible phosphorylation of Drp1 by cyclic AMP-dependent protein kinase and calcineurin regulates mitochondrial fission and cell death | Q29620448 | ||
| Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin | Q29622838 | ||
| Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons. | Q30477849 | ||
| From fixed to FRAP: measuring protein mobility and activity in living cells | Q30673954 | ||
| An RNAi screen for mitochondrial proteins required to maintain the morphology of the organelle in Caenorhabditis elegans | Q33313238 | ||
| PINK1 defect causes mitochondrial dysfunction, proteasomal deficit and alpha-synuclein aggregation in cell culture models of Parkinson's disease | Q33412371 | ||
| Silencing of PINK1 expression affects mitochondrial DNA and oxidative phosphorylation in dopaminergic cells | Q33415997 | ||
| The biochemistry of Parkinson's disease | Q34426026 | ||
| Mitochondrial fusion and fission in mammals | Q34526830 | ||
| Mutations in LRRK2/dardarin associated with Parkinson disease are more toxic than equivalent mutations in the homologous kinase LRRK1. | Q34613694 | ||
| The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization | Q34836156 | ||
| Reactive oxygen and nitrogen species: weapons of neuronal destruction in models of Parkinson's disease | Q36125002 | ||
| Mitochondrial participation in the intracellular Ca2+ network | Q36254615 | ||
| Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP. | Q36446511 | ||
| Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery | Q36657599 | ||
| CaM kinase I alpha-induced phosphorylation of Drp1 regulates mitochondrial morphology | Q36817918 | ||
| Functions and dysfunctions of mitochondrial dynamics | Q36967747 | ||
| Mitochondrial function and morphology are impaired in parkin-mutant fibroblasts | Q37036351 | ||
| Mitochondrial fusion, fission and autophagy as a quality control axis: the bioenergetic view | Q37179623 | ||
| Co-ordinate transcriptional regulation of dopamine synthesis genes by alpha-synuclein in human neuroblastoma cell lines | Q38355256 | ||
| Drp-1-dependent division of the mitochondrial network blocks intraorganellar Ca2+ waves and protects against Ca2+-mediated apoptosis | Q39697070 | ||
| PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death | Q39873016 | ||
| Mutant Pink1 induces mitochondrial dysfunction in a neuronal cell model of Parkinson's disease by disturbing calcium flux | Q39891449 | ||
| Mitochondrial oxidative phosphorylation and energetic status are reflected by morphology of mitochondrial network in INS-1E and HEP-G2 cells viewed by 4Pi microscopy. | Q39985951 | ||
| Proteomic identification of p53-dependent protein phosphorylation. | Q39988127 | ||
| Pink1 Parkinson mutations, the Cdc37/Hsp90 chaperones and Parkin all influence the maturation or subcellular distribution of Pink1. | Q40051916 | ||
| The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1. | Q40074115 | ||
| Mitochondrial bioenergetics and structural network organization | Q40171308 | ||
| Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6. | Q40201823 | ||
| Small interfering RNA targeting the PINK1 induces apoptosis in dopaminergic cells SH-SY5Y. | Q40361843 | ||
| Wild-type PINK1 prevents basal and induced neuronal apoptosis, a protective effect abrogated by Parkinson disease-related mutations | Q40389365 | ||
| Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death. | Q40670474 | ||
| Parkin mitochondria in the autophagosome | Q41391888 | ||
| Ca2+ shuttling between endoplasmic reticulum and mitochondria underlying Ca2+ oscillations | Q41916307 | ||
| Dominant role of mitochondria in clearance of large Ca2+ loads from rat adrenal chromaffin cells. | Q42514013 | ||
| Coordinate changes in neuronal phenotype and surface antigen expression in human neuroblastoma cell variants. | Q43996414 | ||
| Impairing the bioenergetic status and the biogenesis of mitochondria triggers mitophagy in yeast | Q46538168 | ||
| Genetic and genomic studies of Drosophila parkin mutants implicate oxidative stress and innate immune responses in pathogenesis. | Q52655035 | ||
| The PINK1-Parkin pathway is involved in the regulation of mitochondrial remodeling process. | Q52695435 | ||
| Cyclic AMP-dependent protein kinase phosphorylation of Drp1 regulates its GTPase activity and mitochondrial morphology. | Q53548157 | ||
| Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission. | Q53571110 | ||
| The SUMO protease SENP5 is required to maintain mitochondrial morphology and function | Q56907347 | ||
| Expression and precursor processing of neuropeptide Y in human and murine neuroblastoma and pheochromocytoma cell lines | Q69383992 | ||
| Mdm38 protein depletion causes loss of mitochondrial K+/H+ exchange activity, osmotic swelling and mitophagy | Q80413458 | ||
| P275 | copyright license | Creative Commons CC0 License | Q6938433 |
| P6216 | copyright status | copyrighted, dedicated to the public domain by copyright holder | Q88088423 |
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| ImageQuant | Q112270642 | ||
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | e5701 | |
| P577 | publication date | 2009-05-27 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1. | |
| P478 | volume | 4 |
| Q30413675 | A calcineurin docking motif (LXVP) in dynamin-related protein 1 contributes to mitochondrial fragmentation and ischemic neuronal injury. |
| Q33871331 | A pivotal role for PINK1 and autophagy in mitochondrial quality control: implications for Parkinson disease |
| Q37607449 | Abnormal mitochondrial dynamics and neurodegenerative diseases |
| Q34927824 | Autophagy-mediated turnover of dynamin-related protein 1. |
| Q38856274 | BIRC5/Survivin as a target for glycolysis inhibition in high-stage neuroblastoma. |
| Q37782121 | Balance is the challenge – The impact of mitochondrial dynamics in Parkinson’s disease |
| Q34379744 | Beyond the mitochondrion: cytosolic PINK1 remodels dendrites through protein kinase A |
| Q47265377 | Biological Implications of Differential Expression of Mitochondrial-Shaping Proteins in Parkinson's Disease. |
| Q38152235 | Ca2+ in quality control: an unresolved riddle critical to autophagy and mitophagy. |
| Q37466088 | Cause and consequence: mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases. |
| Q40394013 | Cell metabolism affects selective vulnerability in PINK1-associated Parkinson's disease |
| Q26853356 | Cell signaling and mitochondrial dynamics: Implications for neuronal function and neurodegenerative disease |
| Q36636038 | Characterization of PINK1 (PTEN-induced putative kinase 1) mutations associated with Parkinson disease in mammalian cells and Drosophila |
| Q36810811 | Cytosolic PINK1 promotes the targeting of ubiquitinated proteins to the aggresome-autophagy pathway during proteasomal stress |
| Q34399382 | DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy |
| Q38433683 | DLP1-dependent mitochondrial fragmentation mediates 1-methyl-4-phenylpyridinium toxicity in neurons: implications for Parkinson's disease |
| Q34428732 | Defects in mitochondrial fission protein dynamin-related protein 1 are linked to apoptotic resistance and autophagy in a lung cancer model |
| Q36651556 | Downregulation of Pink1 influences mitochondrial fusion-fission machinery and sensitizes to neurotoxins in dopaminergic cells |
| Q36526622 | Drosophila as a model to study mitochondrial dysfunction in Parkinson's disease |
| Q29615625 | Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin |
| Q28300234 | Dynamin-related protein 1 and mitochondrial fragmentation in neurodegenerative diseases |
| Q33593798 | ERKed by LRRK2: a cell biological perspective on hereditary and sporadic Parkinson's disease |
| Q38093581 | Function and characteristics of PINK1 in mitochondria |
| Q54987165 | Gene-by-environment interactions that disrupt mitochondrial homeostasis cause neurodegeneration in C. elegans Parkinson's models. |
| Q35708874 | Implications of mitochondrial dynamics on neurodegeneration and on hypothalamic dysfunction |
| Q24315046 | Inactivation of Pink1 gene in vivo sensitizes dopamine-producing neurons to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and can be rescued by autosomal recessive Parkinson disease genes, Parkin or DJ-1 |
| Q39655865 | Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1. |
| Q24301357 | LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1 |
| Q37969636 | Less than perfect divorces: dysregulated mitochondrial fission and neurodegeneration. |
| Q35153949 | Loss of PINK1 impairs stress-induced autophagy and cell survival |
| Q39834753 | Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation |
| Q61718173 | Mechanisms of selective autophagy and mitophagy: Implications for neurodegenerative diseases. |
| Q33778336 | Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses |
| Q37889815 | Mitochondria, calcium, and endoplasmic reticulum stress in Parkinson's disease |
| Q39236962 | Mitochondrial Quality Control and Disease: Insights into Ischemia-Reperfusion Injury |
| Q37891820 | Mitochondrial contribution to Parkinson's disease pathogenesis |
| Q28280353 | Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease |
| Q37793525 | Mitochondrial dynamics |
| Q34073939 | Mitochondrial dynamics in Alzheimer's disease: opportunities for future treatment strategies |
| Q36082495 | Mitochondrial dynamics in cancer and neurodegenerative and neuroinflammatory diseases |
| Q37686261 | Mitochondrial dysfunction and mitophagy: the beginning and end to diabetic nephropathy? |
| Q38021865 | Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences |
| Q35799109 | Mitochondrial dysfunction in genetic animal models of Parkinson's disease |
| Q40225096 | Mitochondrial fission in endothelial cells after simulated ischemia/reperfusion: role of nitric oxide and reactive oxygen species |
| Q28084134 | Mitochondrial fusion and fission proteins as novel therapeutic targets for treating cardiovascular disease |
| Q37686255 | Mitochondrial fusion and fission proteins: novel therapeutic targets for combating cardiovascular disease. |
| Q41850035 | Mitochondrial fusion/fission, transport and autophagy in Parkinson's disease: when mitochondria get nasty. |
| Q28115890 | Mitochondrial impairment increases FL-PINK1 levels by calcium-dependent gene expression |
| Q35799128 | Mitochondrial quality control and dynamics in Parkinson's disease |
| Q37732485 | Mitochondrial quality control and neurological disease: an emerging connection |
| Q33603972 | Mitochondrial quality control: insights on how Parkinson's disease related genes PINK1, parkin, and Omi/HtrA2 interact to maintain mitochondrial homeostasis |
| Q27310252 | Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration |
| Q37694547 | Mitochondrial-Shaping Proteins in Cardiac Health and Disease - the Long and the Short of It! |
| Q35223923 | Mitochondrially localized PKA reverses mitochondrial pathology and dysfunction in a cellular model of Parkinson's disease. |
| Q24300975 | Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy |
| Q52601351 | Multiple pathways for mitophagy: A neurodegenerative conundrum for Parkinson's disease. |
| Q36545195 | N-terminal phosphorylation of protein phosphatase 2A/Bβ2 regulates translocation to mitochondria, dynamin-related protein 1 dephosphorylation, and neuronal survival. |
| Q58105465 | No Country for Old Worms: A Systematic Review of the Application of to Investigate a Bacterial Source of Environmental Neurotoxicity in Parkinson's Disease |
| Q33888931 | Oxidative stress causes reversible changes in mitochondrial permeability and structure |
| Q64779288 | PINK1 Interacts with VCP/p97 and Activates PKA to Promote NSFL1C/p47 Phosphorylation and Dendritic Arborization in Neurons |
| Q35577571 | PINK1 enhances insulin-like growth factor-1-dependent Akt signaling and protection against apoptosis. |
| Q21145802 | PINK1 is selectively stabilized on impaired mitochondria to activate Parkin |
| Q47827892 | PINK1 regulates mitochondrial trafficking in dendrites of cortical neurons through mitochondrial PKA. |
| Q24309549 | Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress |
| Q39536018 | Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1. |
| Q37953288 | Parkin, PINK1 and mitochondrial integrity: emerging concepts of mitochondrial dysfunction in Parkinson's disease |
| Q38123809 | Parkin- and PINK1-Dependent Mitophagy in Neurons: Will the Real Pathway Please Stand Up? |
| Q26781796 | Parkinson's disease proteins: Novel mitochondrial targets for cardioprotection |
| Q33871291 | Parkinson's disease: insights from pathways |
| Q36186542 | Parkinsonism due to mutations in PINK1, parkin, and DJ-1 and oxidative stress and mitochondrial pathways |
| Q33799876 | Perturbations in mitochondrial dynamics induced by human mutant PINK1 can be rescued by the mitochondrial division inhibitor mdivi-1. |
| Q35149686 | Pink1 regulates the oxidative phosphorylation machinery via mitochondrial fission |
| Q37705837 | Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels |
| Q41228349 | Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation |
| Q29615623 | Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin |
| Q26829588 | Recent advances into the understanding of mitochondrial fission |
| Q58716523 | Reduction of PINK1 or DJ-1 impair mitochondrial motility in neurites and alter ER-mitochondria contacts |
| Q41786008 | Regulation of mitochondrial permeability transition pore by PINK1. |
| Q37697950 | Ret rescues mitochondrial morphology and muscle degeneration of Drosophila Pink1 mutants |
| Q27021384 | Role of protein kinase A in regulating mitochondrial function and neuronal development: implications to neurodegenerative diseases |
| Q38131751 | SUMO and Parkinson's disease |
| Q37718248 | Targeting mitochondrial dysfunction in neurodegenerative disease: Part II. |
| Q46839158 | The Impact of Mitochondrial Fusion and Fission Modulation in Sporadic Parkinson's Disease. |
| Q30273994 | The PINK1/Parkin pathway regulates mitochondrial dynamics and function in mammalian hippocampal and dopaminergic neurons |
| Q37646370 | The PINK1/Parkin pathway: a mitochondrial quality control system? |
| Q39138747 | The Parkinson's disease-associated gene PINK1 protects neurons from ischemic damage by decreasing mitochondrial translocation of the fission promoter Drp1. |
| Q28587095 | The Parkinson's gene PINK1 regulates cell cycle progression and promotes cancer-associated phenotypes |
| Q39754547 | The Parkinson-associated protein PINK1 interacts with Beclin1 and promotes autophagy |
| Q37815475 | The interplay between mitochondrial dynamics and mitophagy |
| Q33769553 | The loss of PGAM5 suppresses the mitochondrial degeneration caused by inactivation of PINK1 in Drosophila |
| Q34154475 | The mitochondrial chaperone protein TRAP1 mitigates α-Synuclein toxicity |
| Q37111847 | The mitochondrial dynamics of Alzheimer's disease and Parkinson's disease offer important opportunities for therapeutic intervention |
| Q33552320 | The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway |
| Q37639223 | The mitochondrial kinase PINK1, stress response and Parkinson's disease |
| Q38850628 | The mitochondrial kinase PINK1: functions beyond mitophagy |
| Q38201044 | The role of mitochondria in the development and progression of lung cancer |
| Q24307946 | The role of oxidative stress in Parkinson's disease |
| Q27335187 | The yeast complex I equivalent NADH dehydrogenase rescues pink1 mutants |
| Q37466094 | Tickled PINK1: mitochondrial homeostasis and autophagy in recessive Parkinsonism. |
| Q34805897 | To eat or not to eat: neuronal metabolism, mitophagy, and Parkinson's disease |
| Q34201811 | Unravelling the role of defective genes |
| Q37796006 | What have we learned from Drosophila models of Parkinson's disease? |
| Q83034995 | miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1 |
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