BIRC5/Survivin as a target for glycolysis inhibition in high-stage neuroblastoma.

scientific article published on 6 July 2015

BIRC5/Survivin as a target for glycolysis inhibition in high-stage neuroblastoma. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1037467863
P356DOI10.1038/ONC.2015.264
P698PubMed publication ID26148234

P50authorMichael J AusserlechnerQ64683337
Judith HagenbuchnerQ82408236
P2093author name stringU Kiechl-Kohlendorfer
P Obexer
P2860cites workStructure of the human anti-apoptotic protein survivin reveals a dimeric arrangementQ22254394
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Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagyQ28131727
A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancerQ28297827
The Beclin 1 network regulates autophagy and apoptosisQ29616539
Autophagy in health and disease: a double-edged swordQ29618103
Paclitaxel, cisplatin and lonidamine in advanced ovarian cancer. A phase II studyQ32142109
Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1.Q33459240
Regulation of survivin function by Hsp90Q33713035
Differential requirements for survivin in hematopoietic cell developmentQ33913884
A role for survivin in chemoresistance of endothelial cells mediated by VEGFQ34047896
Targeting tumor metabolism with 2-deoxyglucose in patients with castrate-resistant prostate cancer and advanced malignanciesQ34081705
Harmol induces autophagy and subsequent apoptosis in U251MG human glioma cells through the downregulation of survivinQ34323688
High-efficiency gene transfer and selection of human hematopoietic progenitor cells with a hybrid EBV/retroviral vector expressing the green fluorescence proteinQ41072145
Glucose-starved cells do not engage in prosurvival autophagyQ41924376
Greater cell cycle inhibition and cytotoxicity induced by 2-deoxy-d-glucose in tumor cells treated under hypoxic vs aerobic conditionsQ44647527
FOXO3-induced reactive oxygen species are regulated by BCL2L11 (Bim) and SESN3.Q45100601
Complete remission of liver metastasis of pancreatic cancer under vaccination with a HLA-A2 restricted peptide derived from the universal tumor antigen survivinQ46825564
A retroviral expression system based on tetracycline-regulated tricistronic transactivator/repressor vectors for functional analyses of antiproliferative and toxic genes.Q50718091
YM155, a novel small-molecule survivin suppressant, induces regression of established human hormone-refractory prostate tumor xenografts.Q51794884
Regulation of survivin stability by the aryl hydrocarbon receptor-interacting protein.Q53614823
Analysis of human transcriptomes.Q55033453
Selective escape of proteins from the mitochondria during mitophagyQ61207848
High expression of Survivin, mapped to 17q25, is significantly associated with poor prognostic factors and promotes cell survival in human neuroblastomaQ63874527
Therapeutic targeting of the survivin pathway in cancer: initiation of mitochondrial apoptosis and suppression of tumor-associated angiogenesisQ64377539
The antiapoptosis protein survivin is associated with cell cycle entry of normal cord blood CD34(+) cells and modulates cell cycle and proliferation of mouse hematopoietic progenitor cellsQ74805759
Necroptosis in health and diseasesQ34432108
Targeting survivin in cancer: novel drug development approachesQ34954296
Targeting survivin overcomes drug resistance in acute lymphoblastic leukemiaQ35182716
Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effectQ35239585
Survivin, versatile modulation of cell division and apoptosis in cancerQ35591693
Pyruvate protects mitochondria from oxidative stress in human neuroblastoma SK-N-SH cellsQ35753977
Essential role of survivin, an inhibitor of apoptosis protein, in T cell development, maturation, and homeostasis.Q35834685
Suppression of vascular endothelial growth factor-mediated endothelial cell protection by survivin targeting.Q35842152
FOXO3/FKHRL1 is activated by 5-aza-2-deoxycytidine and induces silenced caspase-8 in neuroblastomaQ35998617
Genes proximal and distal to MYCN are highly expressed in human neuroblastoma as visualized by comparative expressed sequence hybridizationQ36357428
Does autophagy contribute to cell death?Q36549462
Proliferation enhanced by NGF-NTRK1 signaling makes pancreatic cancer cells more sensitive to 2DG-induced apoptosisQ36746869
Resistance to hypoxia-induced necroptosis is conferred by glycolytic pyruvate scavenging of mitochondrial superoxide in colorectal cancer cells.Q36907096
Survivin-directed RNA interference cocktail is a potent suppressor of tumour growth in vivoQ36930279
Tetra-O-methyl nordihydroguaiaretic acid induces growth arrest and cellular apoptosis by inhibiting Cdc2 and survivin expressionQ37513265
Mitochondrial survivin inhibits apoptosis and promotes tumorigenesis.Q37574259
Autophagy in the cellular energetic balanceQ37870537
Mitophagy: a complex mechanism of mitochondrial removalQ37955193
Tumor glycolysis as a target for cancer therapy: progress and prospectsQ38168262
Autophagy as a pro-death pathwayQ38261558
YM155 induces apoptosis through downregulation of specificity protein 1 and myeloid cell leukemia-1 in human oral cancer cell linesQ38932250
Glycolysis inhibition and its effect in doxorubicin resistance in neuroblastomaQ38989148
2-deoxy-D-glucose induces oxidative stress and cell killing in human neuroblastoma cellsQ39096682
A novel Mcl1 variant inhibits apoptosis via increased Bim sequestrationQ39122729
2-Deoxyglucose treatment complements the cisplatin- or BH3-only mimetic-induced suppression of neuroblastoma cell growthQ39197274
BIRC5/Survivin enhances aerobic glycolysis and drug resistance by altered regulation of the mitochondrial fusion/fission machinery.Q39245718
2-deoxyglucose induces Noxa-dependent apoptosis in alveolar rhabdomyosarcomaQ39475175
Defective regulation of autophagy upon leucine deprivation reveals a targetable liability of human melanoma cells in vitro and in vivo.Q39541632
The Parkinson-associated protein PINK1 interacts with Beclin1 and promotes autophagyQ39754547
The anti-apoptotic protein BCL2L1/Bcl-xL is neutralized by pro-apoptotic PMAIP1/Noxa in neuroblastoma, thereby determining bortezomib sensitivity independent of prosurvival MCL1 expression.Q39755661
Repression of BIRC5/survivin by FOXO3/FKHRL1 sensitizes human neuroblastoma cells to DNA damage-induced apoptosisQ39884717
Survivin antisense oligonucleotides effectively radiosensitize colorectal cancer cells in both tissue culture and murine xenograft modelsQ39992667
Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6.Q40201823
Heterodimerization of insulin-like growth factor receptor/epidermal growth factor receptor and induction of survivin expression counteract the antitumor action of erlotinib.Q40218927
A phase II study of YM155, a novel small-molecule suppressor of survivin, in castration-resistant taxane-pretreated prostate cancerQ40314536
Phase I study of YM155, a novel survivin suppressant, in patients with advanced solid tumorsQ40388768
Rational design of shepherdin, a novel anticancer agent.Q40422406
Parkin phosphorylation and modulation of its E3 ubiquitin ligase activityQ40489168
Adenovirus-mediated transfer of siRNA against survivin induced apoptosis and attenuated tumor cell growth in vitro and in vivo.Q40539259
Lactate stimulates fibroblast expression of hyaluronan and CD44: the Warburg effect revisitedQ40735665
P433issue16
P407language of work or nameEnglishQ1860
P304page(s)2052-2061
P577publication date2015-07-06
P1433published inOncogeneQ1568657
P1476titleBIRC5/Survivin as a target for glycolysis inhibition in high-stage neuroblastoma
P478volume35

Reverse relations

cites work (P2860)
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