P-gp activity is a critical resistance factor against AVE9633 and DM4 cytotoxicity in leukaemia cell lines, but not a major mechanism of chemoresistance in cells from acute myeloid leukaemia patients

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P-gp activity is a critical resistance factor against AVE9633 and DM4 cytotoxicity in leukaemia cell lines, but not a major mechanism of chemoresistance in cells from acute myeloid leukaemia patients is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1020277867
P356DOI10.1186/1471-2407-9-199
P932PMC publication ID2708190
P698PubMed publication ID19549303
P5875ResearchGate publication ID26313768

P2093author name stringAnne-Marie Faussat
Hamid Morjani
Ollivier Legrand
Fanny Fava
Jean-Pierre Marie
Ruoping Tang
Jean-Yves Perrot
Zora Marjanovic
Claudia Zuany-Amorim
Elise Corre
Simy Cohen
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Antimitotic Activity of the Potent Tumor Inhibitor MaytansineQ67429634
Expression of normal myeloid-associated antigens by acute leukemia cellsQ69990612
Further investigations on the expression of HLA-DR, CD33 and CD13 surface antigens in purified bone marrow and peripheral blood CD34+ haematopoietic progenitor cellsQ72088853
Acute myeloid leukemia in the elderly: assessment of multidrug resistance (MDR1) and cytogenetics distinguishes biologic subgroups with remarkably distinct responses to standard chemotherapy. A Southwest Oncology Group studyQ73292530
Approval summary: gemtuzumab ozogamicin in relapsed acute myeloid leukemiaQ28202341
Class III beta-tubulin mediates sensitivity to chemotherapeutic drugs in non small cell lung cancerQ28251547
Zosuquidar restores drug sensitivity in P-glycoprotein expressing acute myeloid leukemia (AML).Q33319637
Early Clinical Study of an Intermittent Schedule for Maytansine (NSC-153858): Brief Communication 2Q33476825
MDR1/P-GP expression as a prognostic factor in acute leukemias.Q33740303
Transcripts in pretreatment biopsies from a three-arm randomized trial in metastatic non-small-cell lung cancerQ34203414
Class III beta-tubulin overexpression is a marker of poor clinical outcome in advanced ovarian cancer patients.Q34522032
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Cytoskeleton and paclitaxel sensitivity in breast cancer: the role of beta-tubulinsQ38305006
Sequential emergence of MRP- and MDR1-gene over-expression as well as MDR1-gene translocation in homoharringtonine-selected K562 human leukemia cell linesQ38507698
MaytansineQ39785130
A role for altered microtubule polymer levels in vincristine resistance of childhood acute lymphoblastic leukemia xenografts.Q40055597
MRP3, BCRP, and P-glycoprotein activities are prognostic factors in adult acute myeloid leukemiaQ40352994
Gefitinib reverses breast cancer resistance protein-mediated drug resistanceQ40515752
Phase I study of maytansine using a 3-day scheduleQ40887319
Initial clinical trials of maytansine, an antitumor plant alkaloidQ40887323
Maytansine: a phase I study of an ansa macrolide with antitumor activityQ40887329
Multidrug-resistance phenotype and clinical responses to gemtuzumab ozogamicinQ43700140
Prediction of response to docetaxel by quantitative analysis of class I and III beta-tubulin isotype mRNA expression in human breast cancers.Q44545565
Expression of class III beta tubulin in non-small cell lung cancer is correlated with resistance to taxane chemotherapy.Q45304360
New strategies for the treatment of acute myeloid leukemia including antibodies and other novel agentsQ46817128
P275copyright licenseCreative Commons Attribution 2.0 GenericQ19125117
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
cytotoxicityQ246181
P304page(s)199
P577publication date2009-06-23
P1433published inBMC CancerQ326300
P1476titleP-gp activity is a critical resistance factor against AVE9633 and DM4 cytotoxicity in leukaemia cell lines, but not a major mechanism of chemoresistance in cells from acute myeloid leukaemia patients
P478volume9

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