scholarly article | Q13442814 |
P2093 | author name string | Yunfang Li | |
David L Hermanson | |||
Chengguo Xing | |||
Ameeta Kelekar | |||
Nicholas Bleeker | |||
Sonia G Das | |||
Xazmin Lowman | |||
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Structure-activity relationship and molecular mechanisms of ethyl 2-amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017) and its analogues | Q39502559 | ||
Structure-activity relationship and molecular mechanisms of ethyl 2-amino-4-(2-ethoxy-2-oxoethyl)-6-phenyl-4h-chromene-3-carboxylate (sha 14-1) and its analogues | Q39801240 | ||
Dual mechanisms of sHA 14-1 in inducing cell death through endoplasmic reticulum and mitochondria. | Q39832035 | ||
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Noxa up-regulation and Mcl-1 cleavage are associated to apoptosis induction by bortezomib in multiple myeloma | Q40124624 | ||
sHA 14-1, a stable and ROS-free antagonist against anti-apoptotic Bcl-2 proteins, bypasses drug resistances and synergizes cancer therapies in human leukemia cell | Q40150613 | ||
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Anti-apoptotic protein Bcl-2 interacts with and destabilizes the sarcoplasmic/endoplasmic reticulum Ca2+-ATPase (SERCA). | Q42808518 | ||
Multidrug resistance in mitoxantrone-selected HL-60 leukemia cells in the absence of P-glycoprotein overexpression. | Q42815155 | ||
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Upregulation of Bcl-2 is involved in the mediation of chemotherapy resistance in human small cell lung cancer cell lines | Q43864431 | ||
Chemotherapy-induced apoptosis and Bcl-2 levels correlate with breast cancer response to chemotherapy | Q44325712 | ||
Bcl-2 suppresses Ca2+ release through inositol 1,4,5-trisphosphate receptors and inhibits Ca2+ uptake by mitochondria without affecting ER calcium store content | Q44570171 | ||
A phase I trial of continuous infusion of the multidrug resistance inhibitor zosuquidar with daunorubicin and cytarabine in acute myeloid leukemia. | Q46183389 | ||
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P433 | issue | 2 | |
P921 | main subject | multiple drug resistance | Q643839 |
chemotherapy | Q974135 | ||
P304 | page(s) | 327-335 | |
P577 | publication date | 2012-11-05 | |
P1433 | published in | ACS Chemical Biology | Q165583 |
P1476 | title | Ethyl 2-amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017): a novel scaffold that resensitizes multidrug resistant leukemia cells to chemotherapy | |
P478 | volume | 8 |
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Q37027063 | Overexpression of Mcl-1 confers multidrug resistance, whereas topoisomerase IIβ downregulation introduces mitoxantrone-specific drug resistance in acute myeloid leukemia |
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