Rapid cross-linking of an RNA internal loop by the anticancer drug cisplatin

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Rapid cross-linking of an RNA internal loop by the anticancer drug cisplatin is …
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scholarly articleQ13442814

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P356DOI10.1021/JA809637E
P932PMC publication ID2822432
P698PubMed publication ID19566097
P5875ResearchGate publication ID26330081

P2093author name stringVictoria J DeRose
Alethia A Hostetter
Erich G Chapman
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Platinum cross-linking of adenines and guanines on the quadruplex structures of the AG3(T2AG3)3 and (T2AG3)4 human telomere sequences in Na+ and K+ solutionsQ31134580
Platinum anticancer drug damage enforces a particular rotational setting of DNA in nucleosomesQ33934039
Metal ions in the structure and function of RNA.Q34146777
The contribution of metal ions to the structural stability of the large ribosomal subunitQ34365980
New clues for platinum antitumor chemistry: kinetically controlled metal binding to DNA.Q34914365
The ribonome: a dominant force in co-ordinating gene expressionQ35095098
Thiophosphates in yeast U6 snRNA specifically affect pre-mRNA splicingin vitroQ35922209
An ultraviolet light-induced crosslink in yeast tRNA(Phe)Q35924318
RNA-directed transcriptional gene silencing in mammalsQ36134467
From ribosome to riboswitch: control of gene expression in bacteria by RNA structural rearrangementsQ36648410
Direct cellular responses to platinum-induced DNA damageQ36800400
RNA catalysis: ribozymes, ribosomes, and riboswitchesQ36991634
The growing catalog of small RNAs and their association with distinct Argonaute/Piwi family membersQ37089444
"Nought may endure but mutability": spliceosome dynamics and the regulation of splicingQ37197189
Riboswitches: emerging themes in RNA structure and functionQ37197969
A 1,2-d(GpG) cisplatin intrastrand cross-link influences the rotational and translational setting of DNA in nucleosomesQ37336683
Splicing of mRNA precursors: the role of RNAs and proteins in catalysisQ37460883
GG versus AG Platination: A Kinetic Study on Hairpin-Stabilized Duplex OligonucleotidesQ38295511
Sequence specificity of DNA-DNA interstrand cross-link formation by cisplatin and dinuclear platinum complexesQ38308298
More pronounced salt dependence and higher reactivity for platination of the hairpin r(CGCGUUGUUCGCG) compared with d(CGCGTTGTTCGCG).Q38310005
A complete kinetic study of GG versus AG plantination suggests that the doubly aquated derivatives of cisplatin are the actual DNA binding speciesQ38310549
Binding of DNA purine sites to dirhodium compounds probed by mass spectrometryQ38336131
Probing the mechanism of an Mn2+-dependent ribozyme by means of platinum complexesQ38338882
Decay rates of human mRNAs: correlation with functional characteristics and sequence attributesQ38351806
A combined effect of molecular electrostatic potential and N7 accessibility explains sequence-dependent binding of cis-[Pt(NH3)2(H2O)2]2+ to DNA duplexesQ38363435
The molecular theory of polyelectrolyte solutions with applications to the electrostatic properties of polynucleotidesQ39750514
Cisplatin and siRNA interference with structure and function of Wnt-5a mRNA: design and in vitro evaluation of targeting AU-rich elements in the 3' UTR.Q40040349
Inactivation of Tetrahymena rRNA self-splicing by cis-platin proceeds through dissociable complexesQ40504348
Bifunctional binding of cisplatin to DNA: why does cisplatin form 1,2-intrastrand cross-links with ag but not with GA?Q41258864
Conformational energy and structure in canonical and noncanonical forms of tRNA determined by temperature analysis of the rate of s(4)U8-C13 photocrosslinkingQ42611172
U6 snRNA function in nuclear pre-mRNA splicing: a phosphorothioate interference analysis of the U6 phosphate backbone.Q43205489
Platination of the (T2G4)4 telomeric sequence: a structural and cross-linking study.Q43676955
Splicing-related catalysis by protein-free snRNAsQ43770734
Fast interstrand cross-linking of cisplatin-DNA monoadducts compared with intrastrand chelation: a kinetic study using hairpin-stabilized duplex oligonucleotidesQ43916671
Inhibitory effects of anti-tumor platinum compounds on DNA, RNA and protein syntheses in mammalian cells in virtroQ44552882
Theoretical study of cisplatin binding to purine bases: why does cisplatin prefer guanine over adenine?Q44651324
Identification of nuclear proteins that interact with platinum-modified DNA by photoaffinity labelingQ44909086
Platination of full length tRNA(Ala) and truncated versions of the acceptor stem and anticodon loopQ45028457
RNA-selective modification by a platinum(II) complex conjugated to amino- and guanidinoglycosides.Q46027270
A new role for cisplatin: probing ribosomal RNA structureQ46198807
A combination of access to preassociation sites and local accumulation tendency in the direct vicinity of G-N7 controls the rate of platination of single-stranded DNA.Q46396277
RNA polymerase II blockage by cisplatin-damaged DNA. Stability and polyubiquitylation of stalled polymeraseQ46794856
Interactions between mammalian cell DNA and inorganic platinum compounds. II. Interstrand cross-linking of isolated and cellular DNA by platinum(IV) compoundsQ47866082
RNAs regulate biology.Q50705038
Interrelation between whole-body turnover rates of RNA and proteinQ51197208
The Number of Platinum Atoms Binding to DNA, RNA and Protein Molecules of HeLa Cells Treated with Cisplatin at Its Mean Lethal ConcentrationQ55295162
Ribonucleic acid turnover in man:RNA catabolites in urine as measure for the metabolism of each of the three major species of RNAQ68973616
Messenger RNA loses the ability to direct in vitro peptide synthesis following incubation with cisplatinQ70391923
Cisplatin inhibits in vitro translation by preventing the formation of complete initiation complexQ70603368
Isolation of oligoribonucleotides containing intramolecular cross-linksQ71596482
Urinary excretion of modified nucleosides as biological marker of RNA turnover in patients with cancer and AIDSQ71609489
Application of proton NMR spectroscopy to measurement of whole-body RNA degradation rates: effects of surgical stress in human patientsQ71646314
A photo-cross-linkable tertiary structure motif found in functionally distinct RNA molecules is essential for catalytic function of the hairpin ribozymeQ72767119
Inhibition of pre-mRNA splicing by cisplatin and platinum analogsQ73729728
Rates of platination of -AG- and -GA- containing double-stranded oligonucleotides: effect of chloride concentrationQ73833206
Cisplatin (cis-Pt(NH(3))(2)Cl(2)) and cis-[Pt(NH(3))(2)(H(2)O)(2)](2+) Intrastrand Cross-Linking Reactions at the Telomere GGGT DNA Sequence Embedded in a Duplex, a Hairpin, and a Bulged Duplex: Use of Mg(2+) and Zn(2+) to Convert a Hairpin to a BulQ74834942
GG sequence of DNA and the human telomeric sequence react with cis-diammine-diaquaplatinum at comparable ratesQ79561446
Kinetic preference for interaction of cisplatin with the G-C-rich wobble basepair region in both tRNAAla and MhAlaQ79950538
Targeting RNA with small moleculesQ80940656
P4510describes a project that usesImageQuantQ112270642
P433issue26
P407language of work or nameEnglishQ1860
P921main subjectcisplatinQ412415
P304page(s)9250-9257
P577publication date2009-07-01
P1433published inJournal of the American Chemical SocietyQ898902
P1476titleRapid cross-linking of an RNA internal loop by the anticancer drug cisplatin
P478volume131