Randomised comparison of fluorouracil, epidoxorubicin and methotrexate (FEMTX) plus supportive care with supportive care alone in patients with non-resectable gastric cancer

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Randomised comparison of fluorouracil, epidoxorubicin and methotrexate (FEMTX) plus supportive care with supportive care alone in patients with non-resectable gastric cancer is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1030614602
P356DOI10.1038/BJC.1995.114
P932PMC publication ID2033628
P698PubMed publication ID7533517
P5875ResearchGate publication ID15664630

P2093author name stringKuitunen T
Pyrhönen S
Kouri M
Nyandoto P
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P433issue3
P407language of work or nameEnglishQ1860
P921main subjectfluorouracilQ238512
methotrexateQ422232
P304page(s)587-591
P577publication date1995-03-01
P1433published inBritish Journal of CancerQ326309
P1476titleRandomised comparison of fluorouracil, epidoxorubicin and methotrexate (FEMTX) plus supportive care with supportive care alone in patients with non-resectable gastric cancer
P478volume71

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Q33364558Phase II study of capecitabine and cisplatin as first-line combination therapy in patients with gastric cancer recurrent after fluoropyrimidine-based adjuvant chemotherapy
Q36614248Phase II study of capecitabine and irinotecan combination chemotherapy in patients with advanced gastric cancer
Q37336356Phase II study of docetaxel and cisplatin as first-line chemotherapy in patients with recurrent or metastatic gastric cancer
Q83834873Phase II study of docetaxel and cisplatin combination chemotherapy in metastatic gastric cancer
Q37222473Phase II study of low-dose paclitaxel and cisplatin as a second-line therapy after 5-fluorouracil/platinum chemotherapy in gastric cancer
Q33386875Phase II study of oxaliplatin plus S-1 as first-line treatment for advanced gastric cancer (G-SOX study).
Q42986070Phase II study of oxaliplatin, UFT, and leucovorin in patients with metastatic gastric cancer
Q46175387Phase II study of paclitaxel combined with capecitabine as second-line treatment for advanced gastric carcinoma after failure of cisplatin-based regimens
Q36853997Phase II study of paclitaxel, cisplatin, and 5-fluorouracil combination chemotherapy in patients with advanced gastric cancer
Q56776529Phase II study of sequential treatment with S-1 and cisplatin for metastatic gastric cancer
Q42032242Phase II study of short-time oxaliplatin, capecitabine and epirubicin (EXE) as first-line therapy in patients with non-resectable gastric cancer
Q46287658Phase II study of weekly paclitaxel by one-hour infusion for advanced gastric cancer
Q83782142Phase II study of weekly paclitaxel, cisplatin, and 5-fluorouracil for advanced gastric cancer
Q35037527Placebo effects in oncology
Q37651342Postgastrectomy follow-up in the West: evidence base, guidelines, and daily practice
Q37701587Precise integrin-targeting near-infrared imaging-guided surgical method increases surgical qualification of peritoneal carcinomatosis from gastric cancer in mice
Q45921145Predictive factors for the efficacy of cetuximab plus chemotherapy as salvage therapy in metastatic gastric cancer patients.
Q44076876Preoperative assessment of peritoneal carcinomatosis: intraindividual comparison of 18F-FDG PET/CT and MRI.
Q36791086Primary extraosseous Ewing sarcoma of the lung in children
Q41242339Profiling chemotherapy-associated myelotoxicity among Chinese gastric cancer population receiving cytotoxic conventional regimens: epidemiological features, timing, predictors and clinical impacts
Q44365791Prognostic factor analysis in advanced gastric cancer patients treated with hydroxyurea, leucovorin, 5-fluorouracil, and cisplatin (HLFP regimen).
Q51046395Prognostic factor analysis of third-line chemotherapy in patients with advanced gastric cancer.
Q53559950Prognostic factors for survival of patients with advanced gastric cancer treated with cisplatin-based chemotherapy.
Q39778923Progression-free survival and time to progression as surrogate markers of overall survival in patients with advanced gastric cancer: analysis of 36 randomized trials
Q43206575Progression-free survival in first-line chemotherapy is a prognostic factor in second-line chemotherapy in patients with advanced gastric cancer
Q46595662Protective effects of a mixture of antioxidant vitamins and minerals on the genotoxicity of doxorubicin in somatic cells of Drosophila melanogaster
Q50962533Quality of life in patients with advanced gastric cancer treated with second-line chemotherapy.
Q40060365Quality of life with biweekly docetaxel and capecitabine in advanced gastro-oesophageal cancer
Q73379733Raltitrexed (Tomudex) in combination with platinum-based agents and/or anthracyclines: preliminary results of phase I clinical trials
Q36616011Randomised phase II evaluation of irinotecan plus high-dose 5-fluorouracil and leucovorin (ILF) vs 5-fluorouracil, leucovorin, and etoposide (ELF) in untreated metastatic gastric cancer
Q35927364Randomised phase II trial of docetaxel and sunitinib in patients with metastatic gastric cancer who were previously treated with fluoropyrimidine and platinum.
Q53604465Randomized comparison between chemotherapy plus best supportive care with best supportive care in advanced gastric cancer.
Q36396339Randomized multicenter phase III study of a modified docetaxel and cisplatin plus fluorouracil regimen compared with cisplatin and fluorouracil as first-line therapy for advanced or locally recurrent gastric cancer.
Q44441494Randomized phase II study comparing paclitaxel with S-1 vs. S-1 as first-line treatment in patients with advanced gastric cancer
Q64109947Randomized phase II study of second-line chemotherapy with the best available 5-fluorouracil regimen versus weekly administration of paclitaxel in far advanced gastric cancer with severe peritoneal metastases refractory to 5-fluorouracil-containing r
Q34389753Recent advances in chemotherapy for advanced gastric cancer
Q37719335Recent advances in chemotherapy for advanced gastric cancer in Japan
Q36376439Recent developments in the systemic therapy of advanced gastroesophageal malignancies
Q34590788Recent developments in the treatment of gastric carcinoma
Q35445166Refining docetaxel-containing therapy for gastric cancer.
Q36615965Report of two protocol planned interim analyses in a randomised multicentre phase III study comparing capecitabine with fluorouracil and oxaliplatin with cisplatin in patients with advanced oesophagogastric cancer receiving ECF.
Q43067439Results of a randomized and controlled clinical trial evaluating the efficacy and safety of combination therapy with Endostar and S-1 combined with oxaliplatin in advanced gastric cancer
Q37609793Resveratrol reverses Doxorubicin resistance by inhibiting epithelial-mesenchymal transition (EMT) through modulating PTEN/Akt signaling pathway in gastric cancer
Q33729150Retrospective analyses of cisplatin-based doublet combination chemotherapy in patients with advanced gastric cancer
Q42170790Retrospective evaluation of sequential outpatient chemotherapy for advanced gastric cancer
Q59134275Retrospective study of oxaliplatin, leucovarin and 5 fluoruracil regimen in patients with advanced gastric cancer with poor performance status: A study at a tertiary center of South India
Q37052880Review of docetaxel in the treatment of gastric cancer
Q41597654Review: chemotherapy, irradiation and their roles in the management of oesophageal cancer
Q77942693Risk factors associated with mucositis in cancer patients receiving 5-fluorouracil
Q33416469S-1 monotherapy as second line chemotherapy in advanced gastric cancer patients previously treated with cisplatin/infusional fluorouracil
Q56517475S-1 monotherapy as second line chemotherapy in advanced gastric cancer patients previously treated with cisplatin/infusional fluorouracil
Q34588472S-1 plus cisplatin versus S-1 alone for first-line treatment of advanced gastric cancer (SPIRITS trial): a phase III trial
Q44064732S-1 plus oxaliplatin vs. S-1 as first-line treatment in patients with previously untreated advanced gastric cancer: a randomized phase II study
Q33415440S-1-based versus 5-FU-based chemotherapy as first-line treatment in advanced gastric cancer: a meta-analysis of randomized controlled trials
Q42364212Safe use of capecitabine-cisplatin in metastatic gastric carcinoma with severe liver dysfunction: a case report from Algeria
Q37815444Safety and efficacy of S-1 monotherapy in elderly patients with advanced gastric cancer
Q33366124Salvage chemotherapy with irinotecan, 5-fluorouracil and leucovorin for taxane- and cisplatin-refractory, metastatic gastric cancer
Q37992841Second-line chemotherapy for advanced gastric cancer in Korea
Q38750633Second-line chemotherapy for patients with advanced gastric cancer.
Q36964966Second-line chemotherapy for patients with advanced gastric cancer: who may benefit?
Q26778027Second-line treatment of metastatic gastric cancer: Current options and future directions
Q36153493Self-Expandable Metallic Stent Placement in Malignant Gastric Outlet Obstruction: A Comparison Between 2 Brands of Stents
Q44665743Self-reported health-related quality of life predicts survival for patients with advanced gastric cancer treated with first-line chemotherapy
Q35995868Sequential irinotecan hydrochloride/S-1 for S-1-resistant inoperable gastric cancer: A feasibility study
Q60932024Should S-1 be better than capecitabine for patients with advanced gastric cancer in Asia? A systematic review and meta-analysis
Q34782021Should supplemental antioxidant administration be avoided during chemotherapy and radiation therapy?
Q44681408Significance of palliative gastrectomy for late-stage gastric cancer patients
Q33357475Single-Agent Irinotecan as Second-Line Treatment for Advanced Gastric Cancer
Q35095365Status of treatment for advanced gastric carcinoma
Q34608899Superior antitumor activity of nanoparticle albumin-bound paclitaxel in experimental gastric cancer
Q24246675Supportive care for patients with gastrointestinal cancer
Q43996295Surgical complications in gastric cancer patients preoperatively treated with chemotherapy: their risk factors and clinical relevance
Q90321326Surgical management of metastatic gastric cancer: moving beyond the guidelines
Q38031998Surgical treatment of liver metastases of gastric cancer: state of the art.
Q39234296Survival after failure of first-line chemotherapy in advanced gastric cancer patients: differences between Japan and the rest of the world
Q84178293Survival analysis of stage IV metastatic gastric cancer patients treated with HangAm-Plus
Q92617822Survival outcomes after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis from gastric cancer: a systematic review
Q44012763Survival prolongation after treatment failure of first-line chemotherapy in patients with advanced gastric cancer: combined analysis of the Japan Clinical Oncology group trials JCOG9205 and JCOG9912.
Q40300376Synergistic effects of docetaxel and S-1 by modulating the expression of metabolic enzymes of 5-fluorouracil in human gastric cancer cell lines
Q46589174Systemic chemotherapy of TS-1 and cisplatin for gastric signet-ring cell carcinoma presenting as cardiac tamponade
Q54504807TP53 codon 72 polymorphism associated with prognosis in patients with advanced gastric cancer treated with paclitaxel and cisplatin.
Q64100306Targeting interleukin-6 as a strategy to overcome stroma-induced resistance to chemotherapy in gastric cancer
Q35000785Targeting metastatic upper gastrointestinal adenocarcinomas
Q51812919Thalidomide combined with chemotherapy in treating elderly patients with advanced gastric cancer.
Q38941416The Efficacy and Safety of First-line Chemotherapy in Advanced Esophagogastric Cancer: A Network Meta-analysis
Q33577629The GYMSSA trial: a prospective randomized trial comparing gastrectomy, metastasectomy plus systemic therapy versus systemic therapy alone
Q53087621The Italian Research Group for Gastric Cancer (GIRCG) guidelines for gastric cancer staging and treatment: 2015.
Q94526793The Prognostic Value of Neutrophil-to-lymphocyte Ratio and Monocyte-to-lymphocyte Ratio in Metastatic Gastric Cancer Treated with Systemic Chemotherapy
Q42930809The addition of pravastatin to chemotherapy in advanced gastric carcinoma: A randomised phase II trial
Q37400028The changing use of palliative chemotherapy for recurrent esophagogastric cancer: a single center retrospective 15-year review.
Q38116772The diagnostic value of monoclonal gastric cancer 7 antigen: a systematic review with meta-analysis
Q34086875The dual PI3K/mTOR inhibitor NVP-BEZ235 enhances nab-paclitaxel antitumor response in experimental gastric cancer
Q40383915The efficacy and safety of reduced-dose docetaxel, cisplatin, and 5-fluorouracil in the first-line treatment of advanced stage gastric adenocarcinoma
Q36193781The efficacy and toxicity of paclitaxel plus S-1 compared with paclitaxel plus 5-FU for advanced gastric cancer: a PRISMA systematic review and meta-analysis of randomized controlled trials.
Q37477047The efficacy of paclitaxel and cisplatin combination chemotherapy for the treatment of metastatic or recurrent gastric cancer: a multicenter phase II study
Q33437413The efficiency and safety of trastuzumab for advanced gastric and gastroesophageal cancer: a meta-analysis of five randomized controlled trials
Q44108051The evaluation of surgical treatment for gastric cancer patients with noncurative resection
Q44898596The prognostic significance of chemotherapy for stage IV gastric cancer patients: a single-institution experience
Q37427269The progress of targeted therapy in advanced gastric cancer
Q35139161The role of chemotherapy in the current treatment of gastric cancer
Q64105131The role of surgery and radiation in advanced gastric cancer: A population-based study of Surveillance, Epidemiology, and End Results database
Q36097240The role of taxanes in the management of gastroesphageal cancer
Q37731949The significance of multi-line chemotherapy for advanced gastric cancer: A retrospective analysis
Q46817815The symptomatic benefit (the clinical benefit response) from the second-line chemotherapy in patients with advanced gastric adenocarcinoma.
Q38201470The treatment of peritoneal carcinomatosis in advanced gastric cancer: state of the art.
Q50996446The value of palliative gastrectomy in gastric cancer with distant metastasis.
Q33818002Third-line chemotherapy in advanced gastric cancer: A systematic review and meta-analysis
Q33407797Third-line docetaxel chemotherapy for recurrent and metastatic gastric cancer
Q35875892Three-gene predictor of clinical outcome for gastric cancer patients treated with chemotherapy
Q38467530Three-week combination chemotherapy with S-1 and cisplatin as first-line treatment in patients with advanced gastric cancer: a retrospective study with 159 patients
Q43193739Three-weekly S-1 plus cisplatin chemotherapy as first-line treatment for advanced gastric cancer
Q33903541Thymidine Phosphorylase/β-tubulin III expressions predict the response in Chinese advanced gastric cancer patients receiving first-line capecitabine plus paclitaxel
Q37633540Trastuzumab for gastric cancer
Q27851578Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial
Q36220464Trastuzumab: a novel standard option for patients with HER-2-positive advanced gastric or gastro-oesophageal junction cancer
Q90749501Treatment Patterns and Changes in Quality of Life during First-Line Palliative Chemotherapy in Korean Patients with Advanced Gastric Cancer
Q37895575Treatment of gastric cancer with peritoneal carcinomatosis by cytoreductive surgery and HIPEC: a systematic review of survival, mortality, and morbidity
Q45218658Treatment of patients with advanced gastric cancer: experience from an Indian tertiary cancer center
Q53579494Treatment of patients with advanced gastric carcinoma with a 5-fluorouracil-based or a cisplatin-based regimen: two parallel randomized phase II studies.
Q34661367Treatment options in patients with metastatic gastric cancer: current status and future perspectives
Q55379237Treatment patterns and outcomes in patients with metastatic gastric cancer receiving third-line chemotherapy: A population-based outcomes study.
Q33631305Treatment-related severe and fatal adverse events with molecular targeted agents in the treatment of advanced gastric cancer: a meta-analysis
Q34000663Vitamin C enhances anticancer activity in methotrexate‑treated Hep3B hepatocellular carcinoma cells
Q40315009Weekly Taxotere and cisplatin with continuous-infusion 5-fluoruracil for the treatment of advanced gastric and esophageal cancer: a prospective, observational, single-institution experience.
Q33387696Weekly paclitaxel for heavily treated advanced or recurrent gastric cancer refractory to fluorouracil, irinotecan, and cisplatin
Q39682966What is the reference cytotoxic regimen for advanced gastric cancer: standard versus optimal therapy?
Q73315349[Oncology '96]
Q86578814[Treatment of gastric cancer]

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