Enhancement of the priming efficacy of DNA vaccines encoding dendritic cell-targeted antigens by synergistic toll-like receptor ligands.

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Enhancement of the priming efficacy of DNA vaccines encoding dendritic cell-targeted antigens by synergistic toll-like receptor ligands. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1019919444
P356DOI10.1186/1471-2172-10-43
P8608Fatcat IDrelease_eivwikygszd6njuei3duomdgvu
P932PMC publication ID2731061
P698PubMed publication ID19650904
P5875ResearchGate publication ID26713246

P50authorRichard S KornbluthQ78503103
Klaus ÜberlaQ89297358
Matthias TenbuschQ89297763
P2093author name stringGhulam Nabi
Godwin Nchinda
Geoffrey W Stone
Vladimir Temchura
Claudius Grossmann
P2860cites workThe V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoterQ24558779
Multimeric soluble CD40 ligand and GITR ligand as adjuvants for human immunodeficiency virus DNA vaccines.Q27472925
Taking dendritic cells into medicineQ29619243
T-cell quality in memory and protection: implications for vaccine designQ30014840
Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivoQ30080006
Coexpression of GM-CSF and antigen in DNA prime-adenoviral vector boost immunization enhances polyfunctional CD8+ T cell responses, whereas expression of GM-CSF antigen fusion protein induces autoimmunityQ33327757
T cell vaccines for microbial infectionsQ36090185
Intensified and protective CD4+ T cell immunity in mice with anti-dendritic cell HIV gag fusion antibody vaccineQ36228405
The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartmentsQ36342606
Rational design of gene-based vaccinesQ36346123
Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell toleranceQ36376611
In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccinationQ36402359
An HIV-1 clade C DNA prime, NYVAC boost vaccine regimen induces reliable, polyfunctional, and long-lasting T cell responsesQ36446900
The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cellsQ36489528
The microbial mimic poly IC induces durable and protective CD4+ T cell immunity together with a dendritic cell targeted vaccineQ36497412
Antiviral signaling through pattern recognition receptorsQ36693188
Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonistsQ36811131
Toll-like receptor ligands synergize through distinct dendritic cell pathways to induce T cell responses: implications for vaccinesQ36945037
Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cellsQ37139993
A novel cardiotropic murine adenovirus representing a distinct species of mastadenovirusesQ37191886
Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells.Q37418499
Paired Toll-like receptor agonists enhance vaccine therapy through induction of interleukin-12.Q37612522
Recruitment of antigen-presenting cells to the site of inoculation and augmentation of human immunodeficiency virus type 1 DNA vaccine immunogenicity by in vivo electroporationQ38610641
Production of lentiviral vectors by transient expression of minimal packaging genes from recombinant adenovirusesQ40508727
Immunological unresponsiveness characterized by increased expression of CD5 on peripheral T cells induced by dendritic cells in vivoQ40547093
Atraumatic oral spray immunization with replication-deficient viral vector vaccinesQ42910680
EV02: a Phase I trial to compare the safety and immunogenicity of HIV DNA-C prime-NYVAC-C boost to NYVAC-C aloneQ46576663
Induction of CD4+/CD25+ regulatory T cells by targeting of antigens to immature dendritic cellsQ56903879
Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulationQ79213173
Inducing and expanding regulatory T cell populations by foreign antigenQ81392563
Lessons from IAVI-006, a phase I clinical trial to evaluate the safety and immunogenicity of the pTHr.HIVA DNA and MVA.HIVA vaccines in a prime-boost strategy to induce HIV-1 specific T-cell responses in healthy volunteersQ82044309
P921main subjecttoll-like receptorQ408004
dendritic cellQ506253
P304page(s)43
P577publication date2009-08-03
P1433published inBMC ImmunologyQ2877163
P1476titleEnhancement of the priming efficacy of DNA vaccines encoding dendritic cell-targeted antigens by synergistic toll-like receptor ligands
P478volume10

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cites work (P2860)
Q84074937Activation of antigen-specific T cell-responses by mannan-decorated PLGA nanoparticles
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Q47572384CD205 antigen targeting combined with dendritic cell recruitment factors and antigen-linked CD40L activation primes and expands significant antigen-specific antibody and CD4(+) T cell responses following DNA vaccination of outbred animals.
Q37821483Combination adjuvants: the next generation of adjuvants?
Q38124060Combination of adjuvants: the future of vaccine design
Q37772265Control of important helminthic infections vaccine development as part of the solution
Q84335650Cysteine proteases as potential antigens in antiparasitic DNA vaccines
Q47143691Distinct Effects of Monophosphoryl Lipid A, Oligodeoxynucleotide CpG, and Combination Adjuvants on Modulating Innate and Adaptive Immune Responses to Influenza Vaccination
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