Low shear stress can initiate von Willebrand factor-dependent platelet aggregation in patients with type IIB and platelet-type von Willebrand disease

scientific article

Low shear stress can initiate von Willebrand factor-dependent platelet aggregation in patients with type IIB and platelet-type von Willebrand disease is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1172/JCI116735
P932PMC publication ID288303
P698PubMed publication ID8376606

P2093author name stringKawai Y
Watanabe K
Handa M
Ikeda Y
Takahashi H
Satoh K
Yoshioka A
Fujimura Y
Murata M
Fukuyama M
P2860cites workShear-induced platelet aggregation can be mediated by vWF released from platelets, as well as by exogenous large or unusually large vWF multimers, requires adenosine diphosphate, and is resistant to aspirinQ68092762
Modulation of platelet function through adhesion receptors. A dual role for glycoprotein IIb-IIIa (integrin alpha IIb beta 3) mediated by fibrinogen and glycoprotein Ib-von Willebrand factorQ68142029
von Willebrand factor and von Willebrand diseaseQ68187358
The von willebrand factor domain-mediating botrocetin-induced binding to glycoprotein IB lies between Val449 and Lys728Q68828864
Continuous measurement of shear-induced platelet aggregationQ69214411
Cosegregation of von Willebrand factor gene polymorphisms and possible germinal mosaicism in type IIB von Willebrand diseaseQ70127362
Transmembrane calcium influx associated with von Willebrand factor binding to GP Ib in the initiation of shear-induced platelet aggregationQ70463510
Mutation in the gene encoding the alpha chain of platelet glycoprotein Ib in platelet-type von Willebrand diseaseQ24561673
The molecular defect in type IIB von Willebrand disease. Identification of four potential missense mutations within the putative GpIb binding domainQ28776603
Molecular basis of von Willebrand disease type IIB. Candidate mutations cluster in one disulfide loop between proposed platelet glycoprotein Ib binding sequencesQ28776606
Von Willebrand disease associated with familial thrombocytopenia and increased ristocetin-induced platelet aggregationQ33481590
Pseudo-von Willebrand's disease. An intrinsic platelet defect with aggregation by unmodified human factor VIII/von Willebrand factor and enhanced adsorption of its high-molecular-weight multimersQ33481677
Expression of the phenotypic abnormality of platelet-type von Willebrand disease in a recombinant glycoprotein Ib alpha fragmentQ33899500
The role of von Willebrand factor and fibrinogen in platelet aggregation under varying shear stressQ34182746
von Willebrand factor binding to platelet GpIb initiates signals for platelet activationQ34208569
Interaction of asialo von Willebrand factor with glycoprotein Ib induces fibrinogen binding to the glycoprotein IIb/IIIa complex and mediates platelet aggregationQ34624945
Identification of a point mutation in type IIB von Willebrand disease illustrating the regulation of von Willebrand factor affinity for the platelet membrane glycoprotein Ib-IX receptorQ37470139
Duplication of a methionine within the glycoprotein Ib binding domain of von Willebrand factor detected by denaturing gradient gel electrophoresis in a patient with type IIB von Willebrand disease.Q38333045
Shear stress-induced von Willebrand factor binding to platelet glycoprotein Ib initiates calcium influx associated with aggregationQ42461321
von Willebrand factorQ67765089
The interaction of botrocetin with normal or variant von Willebrand factor (types IIA and IIB) and its inhibition by monoclonal antibodies that block receptor bindingQ67802389
The structure and function of von Willebrand factorQ68024145
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectplatelet aggregationQ14913634
P304page(s)1555-1558
P577publication date1993-09-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleLow shear stress can initiate von Willebrand factor-dependent platelet aggregation in patients with type IIB and platelet-type von Willebrand disease
P478volume92

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cites work (P2860)
Q53681302Calpain activation in shear-induced platelet aggregation
Q24319306Crystal structure of the wild-type von Willebrand factor A1-glycoprotein Ibalpha complex reveals conformation differences with a complex bearing von Willebrand disease mutations
Q36798217Mimotope/anti-mimotope probing of structural relationships in platelet glycoprotein Ib alpha
Q34570489Non-dimensional analysis of retinal microaneurysms: critical threshold for treatment
Q40999861Pathogenesis, clinical picture and treatment of von Willebrand's disease
Q36838891Platelet adhesive dynamics. Part II: high shear-induced transient aggregation via GPIbalpha-vWF-GPIbalpha bridging
Q34310946von Willebrand factor self-association on platelet GpIbalpha under hydrodynamic shear: effect on shear-induced platelet activation

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