Expression of the phenotypic abnormality of platelet-type von Willebrand disease in a recombinant glycoprotein Ib alpha fragment

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Expression of the phenotypic abnormality of platelet-type von Willebrand disease in a recombinant glycoprotein Ib alpha fragment is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1172/JCI116438
P932PMC publication ID288214
P698PubMed publication ID8486780

P2093author name stringM Murata
J Ware
Z M Ruggeri
S R Russell
P2860cites workHuman blood platelet adhesion to artery subendothelium is mediated by factor VIII-Von Willebrand factor bound to the subendotheliumQ40713235
Isolation and functional characterization of the von Willebrand factor-binding domain located between residues His1-Arg293 of the alpha-chain of glycoprotein Ib.Q43567942
Identification of a site in the alpha chain of platelet glycoprotein Ib that participates in von Willebrand factor bindingQ43643833
Development of an inhibitor specific to factor VIII: coagulant activity in a patient with platelet-type von Willebrand's diseaseQ45862191
Site-directed mutagenesis of a soluble recombinant fragment of platelet glycoprotein Ib alpha demonstrating negatively charged residues involved in von Willebrand factor bindingQ46469598
Ristocetin and botrocetin involve two distinct domains of von Willebrand factor for binding to platelet membrane glycoprotein IbQ55042554
Identification of discontinuous von Willebrand factor sequences involved in complex formation with botrocetin. A model for the regulation of von Willebrand factor binding to platelet glycoprotein IbQ68010632
Modulation of platelet function through adhesion receptors. A dual role for glycoprotein IIb-IIIa (integrin alpha IIb beta 3) mediated by fibrinogen and glycoprotein Ib-von Willebrand factorQ68142029
Role of botrocetin in platelet agglutination: formation of an activated complex of botrocetin and von Willebrand factorQ69086903
The von Willebrand factor-binding domain of platelet membrane glycoprotein Ib. Characterization by monoclonal antibodies and partial amino acid sequence analysis of proteolytic fragmentsQ70010199
Dimeric ristocetin flocculates proteins, binds to platelets, and mediates von Willebrand factor-dependent agglutination of plateletsQ70144037
Platelet-type von Willebrand's disease: characterization of a new bleeding disorderQ72939306
Mutation in the gene encoding the alpha chain of platelet glycoprotein Ib in platelet-type von Willebrand diseaseQ24561673
High-efficiency transformation of mammalian cells by plasmid DNAQ27860469
Rapid and efficient site-specific mutagenesis without phenotypic selectionQ27860628
The molecular defect in type IIB von Willebrand disease. Identification of four potential missense mutations within the putative GpIb binding domainQ28776603
Molecular basis of von Willebrand disease type IIB. Candidate mutations cluster in one disulfide loop between proposed platelet glycoprotein Ib binding sequencesQ28776606
An LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor CD2Q29614365
Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycolurilQ29618344
Effect of shear rate on platelet interaction with subendothelium in citrated and native blood. I. Shear rate--dependent decrease of adhesion in von Willebrand's disease and the Bernard-Soulier syndromeQ33446498
Decreased adhesion of giant (Bernard-Soulier) platelets to subendothelium. Further implications on the role of the von Willebrand factor in hemostasisQ33463842
von Willebrand factor binds to platelets and induces aggregation in platelet-type but not type IIB von Willebrand diseaseQ33478102
Pseudo-von Willebrand's disease. An intrinsic platelet defect with aggregation by unmodified human factor VIII/von Willebrand factor and enhanced adsorption of its high-molecular-weight multimersQ33481677
Platelets have more than one binding site for von Willebrand factorQ33821754
The role of von Willebrand factor and fibrinogen in platelet aggregation under varying shear stressQ34182746
The platelet glycoprotein Ib-IX complexQ37167635
Identification of a point mutation in type IIB von Willebrand disease illustrating the regulation of von Willebrand factor affinity for the platelet membrane glycoprotein Ib-IX receptorQ37470139
Developing relationships: arterial platelet adhesion, glycoprotein Ib, and leucine-rich glycoproteins.Q37619389
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)2133-2137
P577publication date1993-05-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleExpression of the phenotypic abnormality of platelet-type von Willebrand disease in a recombinant glycoprotein Ib alpha fragment
P478volume91

Reverse relations

cites work (P2860)
Q36407260Adhesive properties of the isolated amino-terminal domain of platelet glycoprotein Ibalpha in a flow field
Q30482774Flow-induced structural transition in the beta-switch region of glycoprotein Ib
Q93138681Hyperactive GPIb-von Willebrand factor interaction as cause of thrombocytopenia: altered platelet formation versus clearance
Q24314966Identification of three tyrosine residues of glycoprotein Ib alpha with distinct roles in von Willebrand factor and alpha-thrombin binding
Q41125713Immunocytochemical aspects of platelet membrane glycoproteins and adhesive proteins during activation.
Q33493973Low shear stress can initiate von Willebrand factor-dependent platelet aggregation in patients with type IIB and platelet-type von Willebrand disease
Q33499298Megakaryocytes and inherited thrombocytopenias
Q36559664Platelet dysfunction and a high bone mass phenotype in a murine model of platelet-type von Willebrand disease
Q40789645Platelet type von Willebrand disease and registry report: communication from the SSC of the ISTH.
Q41954139Shear-stress-induced von Willebrand factor binding to platelets causes the activation of tyrosine kinase(s)
Q72124489Structural implications of the substitution of Val for Met at residue 239 in the alpha chain of human platelet glycoprotein Ib
Q33560436Visualizing the von Willebrand factor/glycoprotein Ib-IX axis with a platelet-type von Willebrand disease mutation

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