The CCR4-NOT complex physically and functionally interacts with TRAMP and the nuclear exosome

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The CCR4-NOT complex physically and functionally interacts with TRAMP and the nuclear exosome is …
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scholarly articleQ13442814

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P819ADS bibcode2009PLoSO...4.6760A
P356DOI10.1371/JOURNAL.PONE.0006760
P932PMC publication ID2727002
P698PubMed publication ID19707589
P5875ResearchGate publication ID26767640

P2093author name stringMartine A Collart
Geoffroy Colau
Nowel Azzouz
Olesya O Panasenko
P2860cites workSite-specific cross-linking of TBP in vivo and in vitro reveals a direct functional interaction with the SAGA subunit Spt3.Q43247301
SPT3 interacts with TFIID to allow normal transcription in Saccharomyces cerevisiaeQ68203604
The essential function of Not1 lies within the Ccr4-Not complexQ73053740
A new yeast poly(A) polymerase complex involved in RNA quality controlQ21146099
Intergenic transcription is required to repress the Saccharomyces cerevisiae SER3 geneQ22122492
The yin and yang of the exosomeQ24292314
A protein complex required for signal-sequence-specific sorting and translocationQ24315826
Reconstitution, activities, and structure of the eukaryotic RNA exosomeQ24337238
Functions of the exosome in rRNA, snoRNA and snRNA synthesisQ24529845
Ski7p G protein interacts with the exosome and the Ski complex for 3'-to-5' mRNA decay in yeastQ24535685
Yeast exosome mutants accumulate 3'-extended polyadenylated forms of U4 small nuclear RNA and small nucleolar RNAsQ24554352
The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleasesQ24600315
Architecture of the yeast Rrp44 exosome complex suggests routes of RNA recruitment for 3' end processingQ24675358
Structure of the active subunit of the yeast exosome core, Rrp44: diverse modes of substrate recruitment in the RNase II nuclease familyQ27650186
Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiaeQ27861085
Stable mRNP formation and export require cotranscriptional recruitment of the mRNA export factors Yra1p and Sub2p by Hpr1pQ27929754
The yeast Ccr4-Not complex controls ubiquitination of the nascent-associated polypeptide (NAC-EGD) complexQ27930672
Antisense RNA stabilization induces transcriptional gene silencing via histone deacetylation in S. cerevisiae.Q27930683
The Ccr4-Not complex independently controls both Msn2-dependent transcriptional activation--via a newly identified Glc7/Bud14 type I protein phosphatase module--and TFIID promoter distribution.Q27930751
Cell cycle progression in G1 and S phases is CCR4 dependent following ionizing radiation or replication stress in Saccharomyces cerevisiaeQ27931688
Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymeraseQ27932117
Contributions of Trf4p- and Trf5p-dependent polyadenylation to the processing and degradative functions of the yeast nuclear exosomeQ27932187
An array of coactivators is required for optimal recruitment of TATA binding protein and RNA polymerase II by promoter-bound Gcn4pQ27932320
RNA degradation by the exosome is promoted by a nuclear polyadenylation complexQ27932438
A SAGA-independent function of SPT3 mediates transcriptional deregulation in a mutant of the Ccr4-not complex in Saccharomyces cerevisiaeQ27932596
Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6pQ27932846
Subunit architecture of multimeric complexes isolated directly from cellsQ27933735
The PMC2NT domain of the catalytic exosome subunit Rrp6p provides the interface for binding with its cofactor Rrp47p, a nucleic acid-binding proteinQ27934035
Rrp47p is an exosome-associated protein required for the 3' processing of stable RNAs.Q27935348
A single subunit, Dis3, is essentially responsible for yeast exosome core activityQ27935552
NOT1(CDC39), NOT2(CDC36), NOT3, and NOT4 encode a global-negative regulator of transcription that differentially affects TATA-element utilizationQ27935983
Probing genuine strong interactions and post-translational modifications in the heterogeneous yeast exosome protein complex.Q27936962
The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiaeQ27937565
The Ccr4-not complex regulates Skn7 through Srb10 kinaseQ27938384
Comparative multiplexed mass spectrometric analyses of endogenously expressed yeast nuclear and cytoplasmic exosomes.Q27939249
Processing of the precursors to small nucleolar RNAs and rRNAs requires common componentsQ27940213
Designer deletion strains derived from Saccharomyces cerevisiae S288C: A useful set of strains and plasmids for PCR-mediated gene disruption and other applicationsQ28131600
Elevated recombination rates in transcriptionally active DNAQ28131616
Nascent-polypeptide-associated complexQ28217074
The nuclear RNA surveillance machinery: the link between ncRNAs and genome structure in budding yeast?Q28265591
Processing of a dicistronic small nucleolar RNA precursor by the RNA endonuclease Rnt1Q28769587
Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiaeQ29546523
Drag&Drop cloning in yeastQ31142202
CDC39, an essential nuclear protein that negatively regulates transcription and differentially affects the constitutive and inducible HIS3 promotersQ34041145
The Ccr4-not complex and yTAF1 (yTaf(II)130p/yTaf(II)145p) show physical and functional interactionsQ34286148
Ccr4-not complex mRNA deadenylase activity contributes to DNA damage responses in Saccharomyces cerevisiaeQ34570125
Functional interaction of CCR4-NOT proteins with TATAA-binding protein (TBP) and its associated factors in yeast.Q34609942
Global control of gene expression in yeast by the Ccr4-Not complexQ35212570
The eukaryotic Ccr4-not complex: a regulatory platform integrating mRNA metabolism with cellular signaling pathways?Q35805081
Analysis of P-body assembly in Saccharomyces cerevisiaeQ35810641
Characterization of an SNR gene locus in Saccharomyces cerevisiae that specifies both dispensible and essential small nuclear RNAsQ36793017
Nascent polypeptide-associated complex stimulates protein import into yeast mitochondriaQ36919506
Ribosome association and stability of the nascent polypeptide-associated complex is dependent upon its own ubiquitinationQ37102597
Specific roles for the Ccr4-Not complex subunits in expression of the genomeQ37131649
Regulation of an intergenic transcript controls adjacent gene transcription in Saccharomyces cerevisiae.Q39705425
Antisense transcription controls cell fate in Saccharomyces cerevisiaeQ42603749
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue8
P407language of work or nameEnglishQ1860
P304page(s)e6760
P577publication date2009-08-25
P1433published inPLOS OneQ564954
P1476titleThe CCR4-NOT complex physically and functionally interacts with TRAMP and the nuclear exosome
P478volume4

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cites work (P2860)
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Q38945894Divergence of the expression and subcellular localization of CCR4-associated factor 1 (CAF1) deadenylase proteins in Oryza sativa
Q35262494Implication of Ccr4-Not complex function in mRNA quality control in Saccharomyces cerevisiae
Q35077099Not4 E3 Ligase Contributes to Proteasome Assembly and Functional Integrity in Part through Ecm29
Q33658496Novel roles of the multi-functional CCR4-NOT complex in post-transcriptional regulation
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Q35996334The exosome controls alternative splicing by mediating the gene expression and assembly of the spliceosome complex.
Q37477468The fate of the messenger is pre-determined: A new model for regulation of gene expression
Q26825398The long and the short of it: The role of the zinc finger polyadenosine RNA binding protein, Nab2, in control of poly(A) tail length
Q27933267The multifunctional Ccr4-Not complex directly promotes transcription elongation
Q39255648The novel tumor suppressor NOL7 post-transcriptionally regulates thrombospondin-1 expression
Q34150385To polyadenylate or to deadenylate: that is the question
Q38050570Transcription coupled repair at the interface between transcription elongation and mRNP biogenesis
Q39771244Transcriptomic analysis of in vivo and in vitro produced bovine embryos revealed a developmental change in cullin 1 expression during maternal-to-embryonic transition
Q36936319Translational Capacity of a Cell Is Determined during Transcription Elongation via the Ccr4-Not Complex

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