alphaB-crystallin regulation of angiogenesis by modulation of VEGF.

scientific article

alphaB-crystallin regulation of angiogenesis by modulation of VEGF. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1182/BLOOD-2009-01-197095
P932PMC publication ID2858494
P698PubMed publication ID20023214

P2093author name stringDavid R Hinton
Shozo Sonoda
Shikun He
Stephen J Ryan
Ram Kannan
Christine Spee
Satoru Kase
Mizuki Kitamura
Eric Wawrousek
P2860cites workHuman alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosisQ24306784
MKBP, a novel member of the small heat shock protein family, binds and activates the myotonic dystrophy protein kinaseQ24315686
Retinopathy of prematurityQ79858093
Interactions between important regulatory proteins and human alphaB crystallinQ80289371
One step at a time: endoplasmic reticulum-associated degradationQ24658302
Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complexQ24670129
The biology of VEGF and its receptorsQ27860704
Intrachoroidal neovascularization in transgenic mice overexpressing vascular endothelial growth factor in the retinal pigment epitheliumQ28359761
AlphaB-crystallin in lens development and muscle integrity: a gene knockout approachQ28512665
betaA3/A1-crystallin in astroglial cells regulates retinal vascular remodeling during developmentQ28574202
Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxiaQ28585065
alpha-Crystallin distribution in retinal pigment epithelium and effect of gene knockouts on sensitivity to oxidative stressQ28592083
Prevalence of age-related macular degeneration in the United StatesQ29614964
The angio-fibrotic switch of VEGF and CTGF in proliferative diabetic retinopathyQ30845192
Subconjunctival doxifluridine administration suppresses rat choroidal neovascularization through activated thymidine phosphorylaseQ31127855
Retinal pigment epithelium is protected against apoptosis by alphaB-crystallin.Q33185028
Soluble EphB4 regulates choroidal endothelial cell function and inhibits laser-induced choroidal neovascularizationQ33227689
N-(4-hydroxyphenyl) retinamide augments laser-induced choroidal neovascularization in miceQ33323010
Effects of hypoxia on stress proteins in the piglet heart at birthQ33736455
Transdifferentiated retinal pigment epithelial cells are immunoreactive for vascular endothelial growth factor in surgically excised age-related macular degeneration-related choroidal neovascular membranes.Q34062411
Crystallins in the eye: Function and pathologyQ34573270
Vascular endothelial growth factor biology: clinical implications for ocular treatmentsQ35762769
Proteasome-dependent regulation of signal transduction in retinal pigment epithelial cellsQ36087272
Vascular endothelial growth factor in eye diseaseQ36929380
Anti-vascular endothelial growth factor therapy for ocular neovascular diseaseQ37046559
MG-132 inhibits telomerase activity, induces apoptosis and G(1) arrest associated with upregulated p27kip1 expression and downregulated survivin expression in gastric carcinoma cellsQ39903879
MG132 proteasome inhibitor modulates proinflammatory cytokines production and expression of their receptors in U937 cells: involvement of nuclear factor-kappaB and activator protein-1.Q40009131
Mimicking phosphorylation of alphaB-crystallin affects its chaperone activityQ41084011
alphaB-crystallin is a novel predictor of resistance to neoadjuvant chemotherapy in breast cancerQ42520912
The small heat shock protein alpha B-crystallin negatively regulates cytochrome c- and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic maturationQ43556597
Response of experimental retinal neovascularization to thiazolidinedionesQ43603007
alphaB-crystallin suppresses oxidative stress-induced astrocyte apoptosis by inhibiting caspase-3 activationQ43673843
Budesonide reduces vascular endothelial growth factor secretion and expression in airway (Calu-1) and alveolar (A549) epithelial cellsQ43705240
Mimicking phosphorylation of alphaB-crystallin on serine-59 is necessary and sufficient to provide maximal protection of cardiac myocytes from apoptosisQ44306740
Chapter 6. Ocular models of angiogenesisQ44390529
Mimicking phosphorylation of the small heat-shock protein alphaB-crystallin recruits the F-box protein FBX4 to nuclear SC35 specklesQ45128868
Apoptosis in surgically excised choroidal neovascular membranes in age-related macular degeneration.Q45941951
Proteasome inhibitor MG132 inhibits angiogenesis in pancreatic cancer by blocking NF-kappaB activity.Q46033964
The effect of proteasome inhibitor MG132 on experimental inflammatory bowel disease.Q46120621
Differential expression of pro- and antiangiogenic factors in mouse strain-dependent hypoxia-induced retinal neovascularizationQ46459264
alphaB-crystallin promotes tumor angiogenesis by increasing vascular survival during tube morphogenesisQ46862778
In vivo models of proliferative vitreoretinopathyQ46951405
Protective and therapeutic role for alphaB-crystallin in autoimmune demyelinationQ46968199
Distinctive immunohistochemical profiles of small heat shock proteins (heat shock protein 27 and alpha B-crystallin) in human brain tumors.Q55479922
The potential angiogenic role of macrophages in the formation of choroidal neovascular membranesQ78106430
P433issue16
P407language of work or nameEnglishQ1860
P921main subjectangiogenesisQ539568
P304page(s)3398-3406
P577publication date2009-12-18
P1433published inBloodQ885070
P1476titlealphaB-crystallin regulation of angiogenesis by modulation of VEGF.
P478volume115

Reverse relations

cites work (P2860)
Q50146188A specific phosphorylation regulates the protective role of αA-crystallin in diabetes
Q40097047Acetylation of αA-crystallin in the human lens: effects on structure and chaperone function.
Q39052915Advances in understanding and management of retinopathy of prematurity
Q58799678Alpha B-crystallin C-802G polymorphism and colorectal cancer susceptibility and clinical outcome in Chinese population
Q34371573Alpha B-crystallin correlates with poor survival in colorectal cancer
Q36552193Alpha B-crystallin is a new prognostic marker for laryngeal squamous cell carcinoma
Q37670926Alpha beta-crystallin expression and presentation following infection with murine gammaherpesvirus 68.
Q36326891Alpha crystallins in the retinal pigment epithelium and implications for the pathogenesis and treatment of age-related macular degeneration
Q54209308Alpha-B-crystallin expression in human laryngeal squamous cell carcinoma tissues.
Q35153884Angiogenesis in diabetes and obesity
Q36784092Antiapoptotic properties of α-crystallin-derived peptide chaperones and characterization of their uptake transporters in human RPE cells
Q42374712Bone Marrow-Derived Cell Recruitment to the Neurosensory Retina and Retinal Pigment Epithelial Cell Layer Following Subthreshold Retinal Phototherapy
Q36739408Chronic oxidative stress upregulates Drusen-related protein expression in adult human RPE stem cell-derived RPE cells: a novel culture model for dry AMD.
Q35209209Comparison of genome-wide gene expression in suture- and alkali burn-induced murine corneal neovascularization.
Q36266703Deficiency of αB crystallin augments ER stress-induced apoptosis by enhancing mitochondrial dysfunction
Q34462869ERK-regulated αB-crystallin induction by matrix detachment inhibits anoikis and promotes lung metastasis in vivo
Q21261248Effect of hypoxia on the expression of αB-crystallin in head and neck squamous cell carcinoma
Q36336018Effect of proline rich 15-deficiency on trophoblast viability and survival
Q43699188Elevated expression of CRYAB predicts unfavorable prognosis in non-small cell lung cancer
Q85026964Four proteins governing overangiogenic endothelial cell phenotype in patients with multiple myeloma are plausible therapeutic targets
Q28655525Functions of crystallins in and out of lens: roles in elongated and post-mitotic cells
Q55461236Glioblastoma-associated stromal cells (GASCs) from histologically normal surgical margins have a myofibroblast phenotype and angiogenic properties.
Q59335459Heat Shock Proteins Regulatory Role in Neurodevelopment
Q37604841Hypoxia inducible factor-1α directly regulates nuclear clusterin transcription by interacting with hypoxia response elements in the clusterin promoter
Q51280068Increased levels of alphaB-crystallin in vitreous fluid of patients with proliferative diabetic retinopathy and correlation with vascular endothelial growth factor.
Q84984868Loss of Arnt (Hif1β) in mouse epidermis triggers dermal angiogenesis, blood vessel dilation and clotting defects
Q38443894Medical implications of understanding the functions of human small heat shock proteins.
Q38268027Methionine sulfoxide reductase A: Structure, function and role in ocular pathology
Q37813204New focus on alpha-crystallins in retinal neurodegenerative diseases
Q36319594Novel roles for α-crystallins in retinal function and disease
Q37398573One size does not fit all: the oligomeric states of αB crystallin
Q34185266Over-expression of BMP4 inhibits experimental choroidal neovascularization by modulating VEGF and MMP-9.
Q41577641Phosphorylation of alphaB-crystallin in epiretinal membrane of human proliferative diabetic retinopathy
Q26785450Phosphorylation of αB-crystallin: Role in stress, aging and patho-physiological conditions
Q34414073Physiological expression of lens α-, β-, and γ-crystallins in murine and human corneas
Q27329045Protection of retina by αB crystallin in sodium iodate induced retinal degeneration
Q48912859Proteomic analysis of oligodendrogliomas expressing a mutant isocitrate dehydrogenase-1.
Q38492019Proteomic analysis of the aqueous humor in patients with wet age-related macular degeneration
Q37018247Rat retinal transcriptome: effects of aging and AMD-like retinopathy
Q43746368Reduction of experimental diabetic vascular leakage and pericyte apoptosis in mice by delivery of αA-crystallin with a recombinant adenovirus
Q58793702Resistance to retinopathy development in obese, diabetic and hypertensive ZSF1 rats: an exciting model to identify protective genes
Q36266092Resveratrol inhibits epithelial-mesenchymal transition of retinal pigment epithelium and development of proliferative vitreoretinopathy
Q39393316Soluble HSPB1 regulates VEGF-mediated angiogenesis through their direct interaction.
Q92002374Stem cell-derived retinal pigment epithelium from patients with age-related macular degeneration exhibit reduced metabolism and matrix interactions
Q41653973Strand and Cell Type-specific Function of microRNA-126 in Angiogenesis
Q59792740Sub-Toxic Human Amylin Fragment Concentrations Promote the Survival and Proliferation of SH-SY5Y Cells via the Release of VEGF and HspB5 from Endothelial RBE4 Cells
Q34581539Targeting the IRE1α/XBP1 and ATF6 arms of the unfolded protein response enhances VEGF blockade to prevent retinal and choroidal neovascularization.
Q35643535Temporal and spatial changes in VEGF, αA- and αB-crystallin expression in a mouse model of oxygen-induced retinopathy
Q46658461The Protective Effects of αB-Crystallin on Ischemia-Reperfusion Injury in the Rat Retina
Q35768528The genetic control of avascular area in mouse oxygen-induced retinopathy
Q42126431The mitochondria-targeted antioxidant SkQ1 restores αB-crystallin expression and protects against AMD-like retinopathy in OXYS rats
Q26852080The unfolded protein response in retinal vascular diseases: implications and therapeutic potential beyond protein folding
Q38404383Therapeutic potential of α-crystallin
Q57212337Thermal denaturation and aggregation of apoform of glycogen phosphorylase b. Effect of crowding agents and chaperones
Q33830446alphaB-crystallin is a marker of aggressive breast cancer behavior but does not independently predict for patient outcome: a combined analysis of two randomized studies.
Q34391371αA crystallin may protect against geographic atrophy-meta-analysis of cataract vs. cataract surgery for geographic atrophy and experimental studies
Q36987607αB-Crystallin Interacts with Nav1.5 and Regulates Ubiquitination and Internalization of Cell Surface Nav1.5.
Q35924024αB-Crystallin Regulates Subretinal Fibrosis by Modulation of Epithelial-Mesenchymal Transition
Q36482872αB-Crystallin regulates expansion of CD11b⁺Gr-1⁺ immature myeloid cells during tumor progression.
Q37056054αB-crystallin is essential for the TGF-β2-mediated epithelial to mesenchymal transition of lens epithelial cells
Q34626414αB-crystallin stimulates VEGF secretion and tumor cell migration and correlates with enhanced distant metastasis in head and neck squamous cell carcinoma
Q36838575αB-crystallin, an effector of unfolded protein response, confers anti-VEGF resistance to breast cancer via maintenance of intracrine VEGF in endothelial cells
Q39113257αB-crystallin/HspB5 regulates endothelial-leukocyte interactions by enhancing NF-κB-induced up-regulation of adhesion molecules ICAM-1, VCAM-1 and E-selectin.
Q37241367αB-crystallin: Portrait of a malignant chaperone as a cancer therapeutic target
Q37173705βA3/A1-crystallin is required for proper astrocyte template formation and vascular remodeling in the retina

Search more.