A key role for membrane transporter NKCC1 in mediating chondrocyte volume increase in the mammalian growth plate

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A key role for membrane transporter NKCC1 in mediating chondrocyte volume increase in the mammalian growth plate is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/JBMR.47
P932PMC publication ID3154001
P698PubMed publication ID20200963
P5875ResearchGate publication ID41722771

P2093author name stringAndrew C Hall
Peter G Bush
Timothy A Damron
Meredith Pritchard
Mohamad Y Loqman
P2860cites workNa-K-2Cl cotransporter inhibition impairs human lung cellular proliferationQ44904443
Hormone-response genes are direct in vivo regulatory targets of Brahma (SWI/SNF) complex function.Q52006413
Differential growth by growth plates as a function of multiple parameters of chondrocytic kinetics.Q52292086
Blockage of Ca-activated Cl conductance by furosemide in rat lacrimal glandsQ68956213
Cellular hydration state: an important determinant of protein catabolism in health and diseaseQ72218746
Cortisol regulation of ion transporter mRNA in Atlantic salmon gill and the effect of salinity on the signaling pathwayQ80642530
Functional analysis of diastrophic dysplasia sulfate transporter. Its involvement in growth regulation of chondrocytes mediated by sulfated proteoglycansQ28270045
Distribution and diversity of Na-K-Cl cotransport proteins: a study with monoclonal antibodiesQ28273930
Molecular cloning, primary structure, and characterization of two members of the mammalian electroneutral sodium-(potassium)-chloride cotransporter family expressed in kidneyQ28581868
Failure of spermatogenesis in mouse lines deficient in the Na(+)-K(+)-2Cl(-) cotransporterQ28593501
Immunolocalization of a Na-K-2Cl cotransporter in human tracheobronchial smooth muscleQ31120797
Microarray analysis of proliferative and hypertrophic growth plate zones identifies differentiation markers and signal pathwaysQ33209716
The osmotic sensitivity of rat growth plate chondrocytes in situ; clarifying the mechanisms of hypertrophyQ33297046
Sodium-potassium-chloride cotransportQ33807206
Intracellular Ca2+ and Cl- channel activation in secretory cells.Q33938757
Age and pattern of the onset of differential growth among growth plates in ratsQ34195198
Clinical pharmacology of furosemide in children: a supplementQ34300767
Immunohistochemical localization of the Na-K-Cl co-transporter (NKCC1) in the gerbil inner ear.Q34430390
Regulation of Na-K-2Cl cotransport by phosphorylation and protein-protein interactionsQ34991748
Molecular cloning and functional expression of the bumetanide-sensitive Na-K-Cl cotransporterQ35099325
Alternatively spliced isoforms of the putative renal Na-K-Cl cotransporter are differentially distributed within the rabbit kidneyQ35242167
Erythrocyte K-Cl cotransport: properties and regulationQ35534126
Volume increase in growth plate chondrocytes during hypertrophy: the contribution of organic osmolytesQ39598768
Kinetics and mechanism of anion transport in red blood cellsQ39846865
Furosemide, a blocker of Na+/K+/2Cl- cotransporter, diminishes proliferation of poorly differentiated human gastric cancer cells by affecting G0/G1 stateQ40217979
Perinuclear localization of Na-K-Cl-cotransporter protein after human cytomegalovirus infectionQ40594795
Na:K:2Cl cotransporter (NKCC) of intestinal epithelial cells. Surface expression in response to cAMP.Q41151247
Growth failure and decreased bone mineral of newborn rats with chronic furosemide therapyQ41492020
Functional significance of cell volume regulatory mechanisms.Q41697457
Stimulation of bumetanide-sensitive Na+/K+/Cl- cotransport by different mitogens in synchronized human skin fibroblasts is essential for cell proliferationQ42217734
Secondary hyperparathyroidism and bone disease in infants receiving long-term furosemide therapyQ42253688
Identification of a sea urchin Na(+)/K(+)/2Cl(-) cotransporter (NKCC): microfilament-dependent surface expression is mediated by hypotonic shock and cyclic AMP.Q43511129
Postnatal maturation of Na+, K+, 2Cl- cotransporter expression and inhibitory synaptogenesis in the rat hippocampus: an immunocytochemical analysisQ43889417
Morphometric analysis of chondrocyte hypertrophyQ43919343
P4510describes a project that usesImageJQ1659584
P433issue7
P304page(s)1594-1603
P577publication date2010-07-01
P1433published inJournal of Bone and Mineral ResearchQ15750941
P1476titleA key role for membrane transporter NKCC1 in mediating chondrocyte volume increase in the mammalian growth plate
P478volume25

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cites work (P2860)
Q37416671A patient with multisystem dysfunction carries a truncation mutation in human SLC12A2, the gene encoding the Na-K-2Cl cotransporter, NKCC1.
Q93216872A simple method based on confocal microscopy and thick sections recognizes seven subphases in growth plate chondrocytes
Q28709612Benzamil sensitive ion channels contribute to volume regulation in canine chondrocytes
Q26865580Cartilage to bone transitions in health and disease
Q37969551Cell volume regulation in chondrocytes
Q47804515Effects of growth hormone treatment on growth plate, bone, and mineral metabolism of young rats with uremia induced by adenine
Q90530034Growth plate alterations in chronic kidney disease
Q42068034Methylation-mediated silencing of miR-124 facilitates chondrogenesis by targeting NFATc1 under hypoxic conditions
Q36711346Multiple phases of chondrocyte enlargement underlie differences in skeletal proportions
Q40630023Plasma Membrane Targeting of Endogenous NKCC2 in COS7 Cells Bypasses Functional Golgi Cisternae and Complex N-Glycosylation
Q64276843Postnatal ex vivo rat model for longitudinal bone growth investigations
Q34978050Quantification of Changes in Morphology, Mechanotransduction, and Gene Expression in Bovine Articular Chondrocytes in Response to 2-Dimensional Culture Indicates the Existence of a Novel Phenotype
Q46845538Suppression of mammalian bone growth by membrane transport inhibitors.
Q92776118The Role of Chondrocyte Morphology and Volume in Controlling Phenotype-Implications for Osteoarthritis, Cartilage Repair, and Cartilage Engineering
Q39383794The phenotypic characterization of A13/BACii, a novel bovine chondrocytic cell line with differentiation potential
Q30572906WNK1-OSR1 kinase-mediated phospho-activation of Na+-K+-2Cl- cotransporter facilitates glioma migration
Q33994691siRNA-mediated inhibition of Na(+)-K(+)-2Cl- cotransporter (NKCC1) and regulatory volume increase in the chondrocyte cell line C-20/A4.

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