Nesprin 1 is critical for nuclear positioning and anchorage

scientific article

Nesprin 1 is critical for nuclear positioning and anchorage is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/HMG/DDP499
P932PMC publication ID2796894
P698PubMed publication ID19864491
P5875ResearchGate publication ID38043573

P2093author name stringKirk L Peterson
Stephan Lange
Ju Chen
Nancy D Dalton
Yusu Gu
Richard L Lieber
Amanda Felder
Andrew P Mizisin
G Diane Shelton
Jianlin Zhang
Ling T Guo
Yujie Liu
P2860cites workSyne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junctionQ22254386
Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissuesQ24292172
Myne-1, a spectrin repeat transmembrane protein of the myocyte inner nuclear membrane, interacts with lamin A/CQ24292190
Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscleQ24292752
Patterns of evolutionary conservation in the nesprin genes highlight probable functionally important protein domains and isoformsQ40026432
Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrityQ40087014
Enaptin, a giant actin-binding protein, is an element of the nuclear membrane and the actin cytoskeletonQ40565474
Desmin knockout muscles generate lower stress and are less vulnerable to injury compared with wild-type musclesQ46666033
Relationship between muscle fiber types and sizes and muscle architectural properties in the mouse hindlimbQ46864051
The KASH domain protein MSP-300 plays an essential role in nuclear anchoring during Drosophila oogenesisQ47070918
Loss of emerin at the nuclear envelope disrupts the Rb1/E2F and MyoD pathways during muscle regeneration.Q52029127
Lamins A and C but not lamin B1 regulate nuclear mechanics.Q53613002
Mutation of SYNE-1, encoding an essential component of the nuclear lamina, is responsible for autosomal recessive arthrogryposisQ84096029
Coupling of the nucleus and cytoplasm: role of the LINC complexQ24299991
NUANCE, a giant protein connecting the nucleus and actin cytoskeletonQ24301510
Nesprin-1alpha self-associates and binds directly to emerin and lamin A in vitroQ24303760
Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffnessQ24318372
Nesprin 4 is an outer nuclear membrane protein that can induce kinesin-mediated cell polarizationQ24320152
Emery-Dreifuss syndromeQ24514959
Structural and functional roles of desmin in mouse skeletal muscle during passive deformationQ24537779
Syne proteins anchor muscle nuclei at the neuromuscular junctionQ24555750
Nesprin-3, a novel outer nuclear membrane protein, associates with the cytoskeletal linker protein plectinQ24679428
Loss of A-type lamin expression compromises nuclear envelope integrity leading to muscular dystrophyQ24681029
Nebulin-deficient mice exhibit shorter thin filament lengths and reduced contractile function in skeletal muscleQ24683625
Selective requirement of myosin light chain 2v in embryonic heart functionQ28258434
The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelopeQ28265573
Abnormal nuclear shape and impaired mechanotransduction in emerin-deficient cellsQ28268495
Role of nuclear lamina-cytoskeleton interactions in the maintenance of cellular strengthQ28269127
Nuclear lamin A/C deficiency induces defects in cell mechanics, polarization, and migrationQ28505944
Lamin A/C and emerin are critical for skeletal muscle satellite cell differentiationQ28511959
Nesprin-2 Giant (NUANCE) maintains nuclear envelope architecture and composition in skinQ28588881
Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervationQ28591836
Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cellsQ29618298
Simultaneous imaging and functional assessment of cytoskeletal protein connections in passively loaded single muscle cellsQ31122639
Positioning of nuclei in Arabidopsis root hairs: an actin-regulated process of tip growthQ33185095
Cellular mechanotransduction: putting all the pieces together againQ34522125
Role of ANC-1 in tethering nuclei to the actin cytoskeleton.Q34647845
Tensegrity II. How structural networks influence cellular information processing networksQ35086156
108th ENMC International Workshop, 3rd Workshop of the MYO-CLUSTER project: EUROMEN, 7th International Emery-Dreifuss Muscular Dystrophy (EDMD) Workshop, 13-15 September 2002, Naarden, The NetherlandsQ35192308
Nesprins: intracellular scaffolds that maintain cell architecture and coordinate cell function?Q36161599
Actin filament cables in Drosophila nurse cells are composed of modules that slide passively past one another during dumpingQ36267678
Reduced thin filament length in nebulin-knockout skeletal muscle alters isometric contractile propertiesQ37190340
SUN1 and SUN2 play critical but partially redundant roles in anchoring nuclei in skeletal muscle cells in miceQ37238766
Disruption of nesprin-1 produces an Emery Dreifuss muscular dystrophy-like phenotype in mice.Q37292920
P4510describes a project that usesImageJQ1659584
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)329-341
P577publication date2009-10-28
P1433published inHuman Molecular GeneticsQ2720965
P1476titleNesprin 1 is critical for nuclear positioning and anchorage
P478volume19

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cites work (P2860)
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Q49490232Are mechanically sensitive regulators involved in the function and (patho)physiology of cerebral palsy-related contractures?
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Q58052113Dominant muscular dystrophy with a novelSYNE1gene mutation
Q47070958Drosophila Nesprin-1 controls glutamate receptor density at neuromuscular junctions.
Q30559349Emerin organizes actin flow for nuclear movement and centrosome orientation in migrating fibroblasts
Q64099828Emery-Dreifuss muscular dystrophy type 4: A new mutation associated with hypertrophic cardiomyopathy masked by a perinatal distress-related spastic diplegia
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Q34597805KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development
Q24336621LINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteins
Q27314986LINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retina
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Q57171613Linker of nucleoskeleton and cytoskeleton complex proteins in cardiomyopathy
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Q47639598Luma is not essential for murine cardiac development and function.
Q36144966Mechanics of the nucleus
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Q38720377Multiple Isoforms of Nesprin1 Are Integral Components of Ciliary Rootlets.
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Q50426653Myofibrils put the squeeze on nuclei
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Q57909897Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration
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Q42377065Nesprin-1α-Dependent Microtubule Nucleation from the Nuclear Envelope via Akap450 Is Necessary for Nuclear Positioning in Muscle Cells
Q37056635Nesprin-3 connects plectin and vimentin to the nuclear envelope of Sertoli cells but is not required for Sertoli cell function in spermatogenesis
Q24338445Nesprin-3 regulates endothelial cell morphology, perinuclear cytoskeletal architecture, and flow-induced polarization
Q34985205Nesprins anchor kinesin-1 motors to the nucleus to drive nuclear distribution in muscle cells
Q58758731Nesprins and Lamins in Health and Diseases of Cardiac and Skeletal Muscles
Q38119634Nesprins: from the nuclear envelope and beyond
Q35144230Nesprins: tissue-specific expression of epsilon and other short isoforms.
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Q43158405Nucleus to Synapse Nesprin1 Railroad Tracks Direct Synapse Maturation through RNA Localization
Q30527771Opposing microtubule motors drive robust nuclear dynamics in developing muscle cells
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Q35923450Sun1 deficiency leads to cerebellar ataxia in mice
Q35105683Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.
Q58693707The Pathogenesis and Therapies of Striated Muscle Laminopathies
Q30584661The SUN protein UNC-84 is required only in force-bearing cells to maintain nuclear envelope architecture
Q36369852The Trypanosoma brucei AIR9-like protein is cytoskeleton-associated and is required for nucleus positioning and accurate cleavage furrow placement
Q37182736The diverse functional LINCs of the nuclear envelope to the cytoskeleton and chromatin
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Q37662431UnLINCing the nuclear envelope: towards an understanding of the physiological significance of nuclear positioning
Q36408413Validation of a Mouse Model to Disrupt LINC Complexes in a Cell-specific Manner

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