| scholarly article | Q13442814 |
| P2093 | author name string | Richard T Lee | |
| Serguei Kozlov | |||
| Jan Lammerding | |||
| P Christian Schulze | |||
| Colin L Stewart | |||
| Janet Hsiao | |||
| P2860 | cites work | Mutations in the gene encoding lamin A/C cause autosomal dominant Emery-Dreifuss muscular dystrophy | Q22009039 |
| Btf, a novel death-promoting transcriptional repressor that interacts with Bcl-2-related proteins | Q22010049 | ||
| Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle | Q24292752 | ||
| Emerin caps the pointed end of actin filaments: evidence for an actin cortical network at the nuclear inner membrane | Q24301949 | ||
| Nesprin-1alpha self-associates and binds directly to emerin and lamin A in vitro | Q24303760 | ||
| Emerin binding to Btf, a death-promoting transcriptional repressor, is disrupted by a missense mutation that causes Emery-Dreifuss muscular dystrophy | Q24315475 | ||
| Identification of a novel X-linked gene responsible for Emery-Dreifuss muscular dystrophy | Q24317622 | ||
| Lamin A/C-dependent localization of Nesprin-2, a giant scaffolder at the nuclear envelope | Q24531346 | ||
| The cell cycle dependent mislocalisation of emerin may contribute to the Emery-Dreifuss muscular dystrophy phenotype | Q77627024 | ||
| Syne proteins anchor muscle nuclei at the neuromuscular junction | Q24555750 | ||
| Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome | Q24562621 | ||
| Homozygous defects in LMNA, encoding lamin A/C nuclear-envelope proteins, cause autosomal recessive axonal neuropathy in human (Charcot-Marie-Tooth disorder type 2) and mouse | Q24632769 | ||
| Loss of A-type lamin expression compromises nuclear envelope integrity leading to muscular dystrophy | Q24681029 | ||
| Missense mutations in the rod domain of the lamin A/C gene as causes of dilated cardiomyopathy and conduction-system disease | Q28139053 | ||
| Nuclear lamin A/C R482Q mutation in canadian kindreds with Dunnigan-type familial partial lipodystrophy | Q28139598 | ||
| Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome | Q28201199 | ||
| Emerin interacts in vitro with the splicing-associated factor, YT521-B | Q28205048 | ||
| Life at the edge: the nuclear envelope and human disease | Q28216767 | ||
| Transcriptional repressor germ cell-less (GCL) and barrier to autointegration factor (BAF) compete for binding to emerin in vitro | Q28218537 | ||
| Aberrant intracellular targeting and cell cycle-dependent phosphorylation of emerin contribute to the Emery-Dreifuss muscular dystrophy phenotype | Q28262405 | ||
| Nuclear membrane protein LAP2beta mediates transcriptional repression alone and together with its binding partner GCL (germ-cell-less) | Q28586861 | ||
| Defects in nuclear structure and function promote dilated cardiomyopathy in lamin A/C-deficient mice | Q28591672 | ||
| Assessment of strain field in endothelial cells subjected to uniaxial deformation of their substrate | Q32065406 | ||
| ANChors away: an actin based mechanism of nuclear positioning | Q33185450 | ||
| Lamin a truncation in Hutchinson-Gilford progeria. | Q34191501 | ||
| Actin is part of pre-initiation complexes and is necessary for transcription by RNA polymerase II. | Q34361619 | ||
| Role of ANC-1 in tethering nuclei to the actin cytoskeleton. | Q34647845 | ||
| Lamin A/C deficiency causes defective nuclear mechanics and mechanotransduction. | Q35632054 | ||
| Multiple and surprising new functions for emerin, a nuclear membrane protein | Q35705383 | ||
| Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure | Q35964554 | ||
| Essential roles for Caenorhabditis elegans lamin gene in nuclear organization, cell cycle progression, and spatial organization of nuclear pore complexes | Q38490249 | ||
| Enaptin, a giant actin-binding protein, is an element of the nuclear membrane and the actin cytoskeleton | Q40565474 | ||
| Staurosporine treatment and serum starvation promote the cleavage of emerin in cultured mouse myoblasts: involvement of a caspase-dependent mechanism | Q40762197 | ||
| Both emerin and lamin C depend on lamin A for localization at the nuclear envelope | Q40771969 | ||
| Relationship between apoptosis and the cell cycle in lymphocytes: roles of protein kinase C, tyrosine phosphorylation, and AP1. | Q41545239 | ||
| Identification of IEX-1 as a biomechanically controlled nuclear factor-kappaB target gene that inhibits cardiomyocyte hypertrophy | Q43948827 | ||
| CDNA microarray analysis of gene expression in fibroblasts of patients with X-linked Emery-Dreifuss muscular dystrophy | Q44819938 | ||
| Actin is closely associated with RNA polymerase II and involved in activation of gene transcription | Q45052244 | ||
| Nuclear envelope alterations in fibroblasts from LGMD1B patients carrying nonsense Y259X heterozygous or homozygous mutation in lamin A/C gene | Q47352477 | ||
| Ultrastructural abnormality of sarcolemmal nuclei in Emery-Dreifuss muscular dystrophy (EDMD). | Q47699129 | ||
| Decreased mechanical stiffness in LMNA-/- cells is caused by defective nucleo-cytoskeletal integrity: implications for the development of laminopathies. | Q51616068 | ||
| LMNA, encoding lamin A/C, is mutated in partial lipodystrophy. | Q54064162 | ||
| Properties of lamin A mutants found in Emery-Dreifuss muscular dystrophy, cardiomyopathy and Dunnigan-type partial lipodystrophy | Q63531530 | ||
| Molecular characterization of the stretch-induced adaptation of cultured cardiac cells. An in vitro model of load-induced cardiac hypertrophy | Q68056099 | ||
| Elliptic fourier analysis of cell and nuclear shapes | Q69720081 | ||
| Mechanical strain tightly controls fibroblast growth factor-2 release from cultured human vascular smooth muscle cells | Q71933756 | ||
| Architectural abnormalities in muscle nuclei. Ultrastructural differences between X-linked and autosomal dominant forms of EDMD | Q73366593 | ||
| Rapid induction and translocation of Egr-1 in response to mechanical strain in vascular smooth muscle cells | Q77215405 | ||
| Nuclear envelope defects associated with LMNA mutations cause dilated cardiomyopathy and Emery-Dreifuss muscular dystrophy | Q77493431 | ||
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cell biology | Q7141 |
| mechanotransduction | Q11936292 | ||
| P304 | page(s) | 781-91 | |
| P577 | publication date | 2005-08-29 | |
| P1433 | published in | Journal of Cell Biology | Q1524550 |
| P1476 | title | Abnormal nuclear shape and impaired mechanotransduction in emerin-deficient cells | |
| P478 | volume | 170 |
| Q34242119 | "Laminopathies": a wide spectrum of human diseases |
| Q92159992 | A multistage sequencing strategy pinpoints novel candidate alleles for Emery-Dreifuss muscular dystrophy and supports gene misregulation as its pathomechanism |
| Q37419142 | A perinuclear actin cap regulates nuclear shape. |
| Q57804538 | A versatile image analysis platform for three-dimensional nuclear reconstruction |
| Q33954299 | Actomyosin tension exerted on the nucleus through nesprin-1 connections influences endothelial cell adhesion, migration, and cyclic strain-induced reorientation |
| Q88959747 | Adjustable viscoelasticity allows for efficient collective cell migration |
| Q37220177 | Adult stem cell maintenance and tissue regeneration in the ageing context: the role for A-type lamins as intrinsic modulators of ageing in adult stem cells and their niches. |
| Q46088014 | Age of heart disease presentation and dysmorphic nuclei in patients with LMNA mutations |
| Q37785157 | Altered mechanical properties of the nucleus in disease |
| Q52654324 | Altered nuclear structure in myotonic dystrophy type 1-derived fibroblasts. |
| Q36175286 | Altering lamina assembly reveals lamina-dependent and -independent functions for A-type lamins. |
| Q92661913 | An Emerin LEM-Domain Mutation Impairs Cell Response to Mechanical Stress |
| Q33290327 | An emerin "proteome": purification of distinct emerin-containing complexes from HeLa cells suggests molecular basis for diverse roles including gene regulation, mRNA splicing, signaling, mechanosensing, and nuclear architecture. |
| Q52957148 | Analysis of Gill Structure from a Fresh Water Fish (Heteropneustes fossilis) Exposed to Bleached Sulfite Pulp Mill Effluents. |
| Q33838220 | Attenuated hypertrophic response to pressure overload in a lamin A/C haploinsufficiency mouse |
| Q34831528 | Biology of the Mi-2/NuRD Complex in SLAC (Stemness, Longevity/Ageing, and Cancer). |
| Q35591191 | Biophysical assays to probe the mechanical properties of the interphase cell nucleus: substrate strain application and microneedle manipulation |
| Q34800912 | Biophysical regulation of histone acetylation in mesenchymal stem cells |
| Q37678536 | Broken nuclei--lamins, nuclear mechanics, and disease. |
| Q38891711 | Causes and consequences of nuclear envelope alterations in tumour progression |
| Q53554488 | Cell nuclei spin in the absence of lamin b1. |
| Q36224478 | Cell shape dependent regulation of nuclear morphology |
| Q34614178 | Cellular mechanosensing: getting to the nucleus of it all. |
| Q42503937 | Cellular strain avoidance is mediated by a functional actin cap - observations in an Lmna-deficient cell model. |
| Q37695969 | Collective cell traction force analysis on aligned smooth muscle cell sheet between three-dimensional microwalls. |
| Q39104972 | Current insights into LMNA cardiomyopathies: Existing models and missing LINCs |
| Q91786551 | DYT1 Dystonia Patient-Derived Fibroblasts Have Increased Deformability and Susceptibility to Damage by Mechanical Forces |
| Q36857698 | Dependence of diffusional mobility of integral inner nuclear membrane proteins on A-type lamins |
| Q27334775 | Design of a microfluidic device to quantify dynamic intra-nuclear deformation during cell migration through confining environments |
| Q34521501 | Direct actin binding to A- and B-type lamin tails and actin filament bundling by the lamin A tail |
| Q37766246 | Directed stem cell differentiation: the role of physical forces |
| Q38991463 | Diseases of the Nucleoskeleton. |
| Q24304005 | Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy |
| Q34772038 | Distinct structural and mechanical properties of the nuclear lamina in Hutchinson-Gilford progeria syndrome |
| Q47070958 | Drosophila Nesprin-1 controls glutamate receptor density at neuromuscular junctions. |
| Q36981772 | Dysfunctional connections between the nucleus and the actin and microtubule networks in laminopathic models. |
| Q35259539 | Emerin in health and disease |
| Q57454036 | Emerin induces nuclear breakage in Xenopus extract and early embryos |
| Q36099092 | Emerin is hyperphosphorylated and redistributed in herpes simplex virus type 1-infected cells in a manner dependent on both UL34 and US3. |
| Q52569974 | Emerin modulates spatial organization of chromosome territories in cells on softer matrices. |
| Q40427155 | Emerin self-assembly mechanism: role of the LEM domain. |
| Q79543221 | Emery-Dreifuss muscular dystrophy |
| Q91997396 | Emery-Dreifuss muscular dystrophy |
| Q35406548 | Evolution: functional evolution of nuclear structure. |
| Q37156605 | Experimental techniques for study of chromatin mechanics in intact nuclei and living cells |
| Q39311831 | Focal adhesion kinase knockdown modulates the response of human corneal epithelial cells to topographic cues |
| Q37383083 | Fraying at the edge mouse models of diseases resulting from defects at the nuclear periphery |
| Q36119056 | Functional association of Sun1 with nuclear pore complexes |
| Q53423711 | Gaussian Curvature Directs Stress Fiber Orientation and Cell Migration. |
| Q36497170 | Genetic mutations and mechanisms in dilated cardiomyopathy |
| Q36514514 | Guilt by association: the nuclear envelope proteome and disease |
| Q90325049 | High-throughput microfluidic micropipette aspiration device to probe time-scale dependent nuclear mechanics in intact cells |
| Q38089892 | Hutchinson-Gilford progeria syndrome through the lens of transcription |
| Q28267181 | Identification of an emerin-beta-catenin complex in the heart important for intercalated disc architecture and beta-catenin localisation |
| Q90443566 | Image analysis of the nuclear characteristics of emerin protein and the correlation with nuclear grooves and intranuclear cytoplasmic inclusions in lung adenocarcinoma |
| Q41882073 | In vitro contracture test results and anaesthetic management of a patient with emery-dreifuss muscular dystrophy for cardiac transplantation |
| Q37117975 | Increased mechanosensitivity and nuclear stiffness in Hutchinson-Gilford progeria cells: effects of farnesyltransferase inhibitors |
| Q34245085 | Integrity matters: linking nuclear architecture to lifespan |
| Q38245736 | Intermediate filaments: a dynamic network that controls cell mechanics |
| Q33859070 | Isolated nuclei adapt to force and reveal a mechanotransduction pathway in the nucleus. |
| Q36109210 | Keeping the LINC: the importance of nucleocytoskeletal coupling in intracellular force transmission and cellular function |
| Q36845695 | LEM-Domain proteins: new insights into lamin-interacting proteins |
| Q34558130 | LINC complexes in health and disease |
| Q64278906 | Lamin A/C and Emerin depletion impacts chromatin organization and dynamics in the interphase nucleus |
| Q34036586 | Lamin A/C and emerin regulate MKL1-SRF activity by modulating actin dynamics |
| Q34072629 | Lamin B1 overexpression increases nuclear rigidity in autosomal dominant leukodystrophy fibroblasts |
| Q47131489 | Lamin B2 binding to minichromosome maintenance complex component 7 promotes non-small cell lung carcinogenesis |
| Q33752204 | Lamin-binding Proteins |
| Q38341565 | Lamins at the crossroads of mechanosignaling |
| Q33551452 | Linker of nucleoskeleton and cytoskeleton complex proteins in cardiac structure, function, and disease |
| Q57171613 | Linker of nucleoskeleton and cytoskeleton complex proteins in cardiomyopathy |
| Q34577033 | Lmo7 is an emerin-binding protein that regulates the transcription of emerin and many other muscle-relevant genes |
| Q90632667 | Local, transient tensile stress on the nuclear membrane causes membrane rupture |
| Q30489484 | Loss of GATA6 leads to nuclear deformation and aneuploidy in ovarian cancer |
| Q52029127 | Loss of emerin at the nuclear envelope disrupts the Rb1/E2F and MyoD pathways during muscle regeneration. |
| Q47639598 | Luma is not essential for murine cardiac development and function. |
| Q24319820 | Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes |
| Q38691260 | Material Cues as Potent Regulators of Epigenetics and Stem Cell Function |
| Q36318027 | Mechanical activation of cells induces chromatin remodeling preceding MKL nuclear transport |
| Q41847622 | Mechanical properties of interphase nuclei probed by cellular strain application |
| Q35606724 | Mechanical properties of the cell nucleus and the effect of emerin deficiency |
| Q36617270 | Mechanical regulation of nuclear structure and function. |
| Q36144966 | Mechanics of the nucleus |
| Q88640354 | Mechanisms of allelic and clinical heterogeneity of lamin A/C phenotypes |
| Q92378153 | Mechanosensing and Mechanoregulation of Endothelial Cell Functions |
| Q39043810 | Mechanosensing by the nucleus: From pathways to scaling relationships. |
| Q86899397 | Mechanotransduction |
| Q38790844 | Mechanotransduction and nuclear function |
| Q37158222 | Mechanotransduction gone awry |
| Q43177507 | Mitochondria as a source of mechanical signals in cardiomyocytes. |
| Q35942479 | Mouse models of the laminopathies. |
| Q21134152 | Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds |
| Q36908213 | Muscular Dystrophy Mutations Impair the Nuclear Envelope Emerin Self-assembly Properties |
| Q33552186 | Nesprin 1 is critical for nuclear positioning and anchorage |
| Q40087014 | Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity |
| Q35908957 | Networking in the nucleus: a spotlight on LEM-domain proteins |
| Q52583668 | New biological research and understanding of Papanicolaou's test. |
| Q93155735 | Nonmuscle myosin IIA and IIB differentially modulate migration and alter gene expression in primary mouse tumorigenic cells |
| Q37590302 | Novel insights into the disease etiology of laminopathies |
| Q35694171 | Novel plant SUN-KASH bridges are involved in RanGAP anchoring and nuclear shape determination |
| Q64125263 | Nuclear Mechanopathology and Cancer Diagnosis |
| Q36319488 | Nuclear Membrane-Targeted Gold Nanoparticles Inhibit Cancer Cell Migration and Invasion |
| Q58761840 | Nuclear Nestin deficiency drives tumor senescence via lamin A/C-dependent nuclear deformation |
| Q26852806 | Nuclear assembly as a target for anti-cancer therapies |
| Q38077664 | Nuclear damages and oxidative stress: new perspectives for laminopathies |
| Q36904931 | Nuclear envelope proteins modulate proliferation of vascular smooth muscle cells during cyclic stretch application |
| Q33856490 | Nuclear envelope structural defects cause chromosomal numerical instability and aneuploidy in ovarian cancer |
| Q28468582 | Nuclear envelope structural proteins facilitate nuclear shape changes accompanying embryonic differentiation and fidelity of gene expression |
| Q34669322 | Nuclear forces and cell mechanosensing. |
| Q35831988 | Nuclear lamins: key regulators of nuclear structure and activities |
| Q37444772 | Nuclear mechanics and mechanotransduction in health and disease |
| Q53542772 | Nuclear mechanics and methods. |
| Q36116300 | Nuclear mechanics in cancer |
| Q37183946 | Nuclear shape, mechanics, and mechanotransduction |
| Q24311440 | Overlapping functions of nuclear envelope proteins NET25 (Lem2) and emerin in regulation of extracellular signal-regulated kinase signaling in myoblast differentiation |
| Q36328105 | Oxydative stress alters nuclear shape through lamins dysregulation: a route to senescence |
| Q36023764 | Physical plasticity of the nucleus in stem cell differentiation |
| Q41670145 | Progress in Integrative Biomaterial Systems to Approach Three-Dimensional Cell Mechanotransduction. |
| Q36798705 | Proteins that associate with lamins: many faces, many functions. |
| Q64071441 | Rare Alleles and Relatively Frequent Alleles Including 'Healthy Lipid' Emerin p.D149H in the ExAC Cohort |
| Q38768262 | Recent advances in understanding nuclear size and shape |
| Q50595914 | Regulation of adipogenesis and osteogenesis in mesenchymal stem cells by vascular endothelial growth factor A. |
| Q47433774 | Regulation of genome organization and gene expression by nuclear mechanotransduction |
| Q27323169 | Role of actin dependent nuclear deformation in regulating early gene expression |
| Q47214734 | Role of the Nucleus as a Sensor of Cell Environment Topography. |
| Q94483667 | Role of the nuclear membrane protein Emerin in front-rear polarity of the nucleus |
| Q91675193 | Roles of the Interhexamer Contact Site for Hexagonal Lattice Formation of the Herpes Simplex Virus 1 Nuclear Egress Complex in Viral Primary Envelopment and Replication |
| Q28509459 | Rootletin interacts with C-Nap1 and may function as a physical linker between the pair of centrioles/basal bodies in cells |
| Q37472616 | Sizing up the nucleus: nuclear shape, size and nuclear-envelope assembly |
| Q44291061 | Spatial coordination between cell and nuclear shape within micropatterned endothelial cells |
| Q52349345 | Spectrin and its interacting partners in nuclear structure and function. |
| Q34808629 | Structural protein 4.1R is integrally involved in nuclear envelope protein localization, centrosome-nucleus association and transcriptional signaling |
| Q35770204 | Sumoylated protein tyrosine phosphatase 1B localizes to the inner nuclear membrane and regulates the tyrosine phosphorylation of emerin |
| Q24296250 | TMEM43 mutations in Emery-Dreifuss muscular dystrophy-related myopathy |
| Q35105683 | Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response. |
| Q99407896 | The NEMP family supports metazoan fertility and nuclear envelope stiffness |
| Q39029494 | The Nuclear Option: Evidence Implicating the Cell Nucleus in Mechanotransduction |
| Q58693707 | The Pathogenesis and Therapies of Striated Muscle Laminopathies |
| Q21090227 | The cell nucleus and aging: tantalizing clues and hopeful promises |
| Q36113002 | The cellular mastermind(?)-mechanotransduction and the nucleus |
| Q41952291 | The emerin-binding transcription factor Lmo7 is regulated by association with p130Cas at focal adhesions |
| Q35920672 | The functions of the nuclear envelope in mediating the molecular crosstalk between the nucleus and the cytoplasm |
| Q28244482 | The molecular basis of emerin-emerin and emerin-BAF interactions |
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| Q37161546 | The nuclear envelope as an integrator of nuclear and cytoplasmic architecture |
| Q28284110 | The nuclear envelope at a glance |
| Q27006719 | The nuclear envelope: an intriguing focal point for neurogenetic disease |
| Q37942354 | The nucleoskeleton as a genome-associated dynamic 'network of networks'. |
| Q51614327 | The role of bifurcation angles on collective smooth muscle cell biomechanics and the implication in atherosclerosis development. |
| Q38753417 | The rotation of mouse myoblast nuclei is dependent on substrate elasticity |
| Q37000133 | Till disassembly do us part: a happy marriage of nuclear envelope and chromatin |
| Q42734888 | Torn apart: membrane rupture in muscular dystrophies and associated cardiomyopathies |
| Q41901094 | Tyrosine phosphorylation of nuclear-membrane protein emerin by Src, Abl and other kinases |
| Q64231853 | Unchain My Heart: Integrins at the Basis of iPSC Cardiomyocyte Differentiation |
| Q42848617 | VRK2A is an A-type lamin-dependent nuclear envelope kinase that phosphorylates BAF. |
| Q37412836 | Vertical nanopillars for in situ probing of nuclear mechanics in adherent cells. |
| Q51081901 | Volume Transitions of Isolated Cell Nuclei Induced by Rapid Temperature Increase. |
| Q27340415 | Volume regulation and shape bifurcation in the cell nucleus |
| Q26827624 | When lamins go bad: nuclear structure and disease |
| Q35634356 | Wild-type levels of human immunodeficiency virus type 1 infectivity in the absence of cellular emerin protein |
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