The insulin degrading enzyme binding domain of varicella-zoster virus (VZV) glycoprotein E is important for cell-to-cell spread and VZV infectivity, while a glycoprotein I binding domain is essential for infection

scientific article

The insulin degrading enzyme binding domain of varicella-zoster virus (VZV) glycoprotein E is important for cell-to-cell spread and VZV infectivity, while a glycoprotein I binding domain is essential for infection is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.VIROL.2009.01.023
P932PMC publication ID2797441
P698PubMed publication ID19233447
P5875ResearchGate publication ID223792160

P2093author name stringElizabeth R Fischer
Jeffrey I Cohen
Mir A Ali
Qingxue Li
P2860cites workInsulin degrading enzyme is a cellular receptor mediating varicella-zoster virus infection and cell-to-cell spreadQ24307918
Entry of alphaherpesviruses mediated by poliovirus receptor-related protein 1 and poliovirus receptorQ24322090
The ectodomain of a novel member of the immunoglobulin subfamily related to the poliovirus receptor has the attributes of a bona fide receptor for herpes simplex virus types 1 and 2 in human cellsQ24523691
Varicella-zoster virus open reading frame 61 protein is functionally homologous to herpes simplex virus type 1 ICP0Q24647866
Herpes simplex virus-1 entry into cells mediated by a novel member of the TNF/NGF receptor familyQ28295196
Varicella-zoster virus gE escape mutant VZV-MSP exhibits an accelerated cell-to-cell spread phenotype in both infected cell cultures and SCID-hu mice.Q30657750
Molecular cloning, sequencing, and expression of functional bovine herpesvirus 1 glycoprotein gIV in transfected bovine cellsQ31019030
The herpes simplex virus gE-gI complex facilitates cell-to-cell spread and binds to components of cell junctionsQ33785316
The extracellular domain of herpes simplex virus gE is sufficient for accumulation at cell junctions but not for cell-to-cell spreadQ33798798
Glycoprotein D or J delivered in trans blocks apoptosis in SK-N-SH cells induced by a herpes simplex virus 1 mutant lacking intact genes expressing both glycoproteinsQ33812868
The extracellular domain of herpes simplex virus gE is indispensable for efficient cell-to-cell spread: evidence for gE/gI receptorsQ33987514
Attenuation of the vaccine Oka strain of varicella-zoster virus and role of glycoprotein C in alphaherpesvirus virulence demonstrated in the SCID-hu mouseQ34069075
The complete DNA sequence of varicella-zoster virusQ34162480
Phosphorylation by the varicella-zoster virus ORF47 protein serine kinase determines whether endocytosed viral gE traffics to the trans-Golgi network or recycles to the cell membraneQ34349663
Transient and stable gene expression in mammalian cells transduced with a recombinant baculovirus vectorQ34793366
Essential functions of the unique N-terminal region of the varicella-zoster virus glycoprotein E ectodomain in viral replication and in the pathogenesis of skin infectionQ35101360
Absence or overexpression of the Varicella-Zoster Virus (VZV) ORF29 latency-associated protein impairs late gene expression and reduces VZV latency in a rodent modelQ35635351
Varicella-zoster virus glycoprotein I is essential for growth of virus in Vero cells.Q35892356
The amino terminus of varicella-zoster virus (VZV) glycoprotein E is required for binding to insulin-degrading enzyme, a VZV receptorQ35947774
Cellular and viral factors regulate the varicella-zoster virus gE promoter during viral replicationQ36099097
Varicella-zoster virus glycoprotein M homolog is glycosylated, is expressed on the viral envelope, and functions in virus cell-to-cell spreadQ36424473
Herpes simplex virus glycoproteins E and I facilitate cell-to-cell spread in vivo and across junctions of cultured cellsQ36626714
Varicella-zoster virus open reading frame 10 protein, the herpes simplex virus VP16 homolog, transactivates herpesvirus immediate-early gene promotersQ36645576
Cell surface expression and fusion by the varicella-zoster virus gH:gL glycoprotein complex: analysis by laser scanning confocal microscopyQ36688025
Use of a glucocorticoid-inducible promoter for expression of herpes simplex virus type 1 glycoprotein gC1, a cytotoxic protein in mammalian cellsQ36756929
Herpes simplex virus glycoprotein D mediates interference with herpes simplex virus infectionQ36780794
Deletions in herpes simplex virus glycoprotein D define nonessential and essential domainsQ36805631
Entry of herpes simplex virus 1 in BJ cells that constitutively express viral glycoprotein D is by endocytosis and results in degradation of the virusQ36825917
Cell lines containing varicella-zoster virus open reading frame 62 and expressing the "IE" 175 protein complement ICP4 mutants of herpes simplex virus type 1.Q36869202
Structural analysis of the varicella-zoster virus gp98-gp62 complex: posttranslational addition of N-linked and O-linked oligosaccharide moietiesQ36899072
Functions of the C-terminal domain of varicella-zoster virus glycoprotein E in viral replication in vitro and skin and T-cell tropism in vivoQ37596576
Characterization of Varicella-Zoster virus glycoprotein K (open reading frame 5) and its role in virus growthQ39550597
Complex formation facilitates endocytosis of the varicella-zoster virus gE:gI Fc receptor.Q39642417
Herpes simplex virus gE/gI expressed in epithelial cells interferes with cell-to-cell spreadQ39700393
Glycoprotein I of varicella-zoster virus is required for viral replication in skin and T cellsQ39753125
Mutational analysis of the role of glycoprotein I in varicella-zoster virus replication and its effects on glycoprotein E conformation and traffickingQ39882103
Receptor properties of two varicella-zoster virus glycoproteins, gpI and gpIV, homologous to herpes simplex virus gE and gIQ40065898
Incorporation of three endocytosed varicella-zoster virus glycoproteins, gE, gH, and gB, into the virion envelopeQ40478161
Glycoprotein E of varicella-zoster virus enhances cell-cell contact in polarized epithelial cellsQ40843597
The varicella zoster virus glycoprotein B (gB) plays a role in virus binding to cell surface heparan sulfate proteoglycansQ41035870
Varicella-zoster virus glycoproteins E and I expressed in insect cells form a heterodimer that requires the N-terminal domain of glycoprotein I.Q41100044
Absence of varicella-zoster virus (VZV) glycoprotein V does not alter growth of VZV in vitro or sensitivity to heparinQ42594535
The acidic amino-terminal region of varicella-zoster virus open reading frame 4 protein is required for transactivation and can functionally replace the corresponding region of herpes simplex virus ICP27.Q42669460
An insulin-degrading enzyme inhibitor decreases amylin degradation, increases amylin-induced cytotoxicity, and increases amyloid formation in insulinoma cell culturesQ44564031
The requirement of varicella zoster virus glycoprotein E (gE) for viral replication and effects of glycoprotein I on gE in melanoma cellsQ45729694
Entry and egress of varicella virus blocked by same anti-gH monoclonal antibodyQ45774660
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectinfectivityQ1662346
P1104number of pages10
P304page(s)270-279
P577publication date2009-02-23
P1433published inVirologyQ7934867
P1476titleThe insulin degrading enzyme binding domain of varicella-zoster virus (VZV) glycoprotein E is important for cell-to-cell spread and VZV infectivity, while a glycoprotein I binding domain is essential for infection
P478volume386

Reverse relations

cites work (P2860)
Q35081168A phase 1/2 study of an adjuvanted varicella-zoster virus subunit vaccine in autologous hematopoietic cell transplant recipients
Q33591823Functions of the unique N-terminal region of glycoprotein E in the pathogenesis of varicella-zoster virus infection
Q36825131Immunogenicity of varicella zoster virus glycoprotein E DNA vaccine
Q34389074Infected peripheral blood mononuclear cells transmit latent varicella zoster virus infection to the guinea pig enteric nervous system
Q33622464Insulin degrading enzyme induces a conformational change in varicella-zoster virus gE, and enhances virus infectivity and stability
Q39782339Insulin-degrading enzyme binds to the nonglycosylated precursor of varicella-zoster virus gE protein found in the endoplasmic reticulum.
Q37633252Interaction of allergy history and antibodies to specific varicella-zoster virus proteins on glioma risk
Q35076854Mutagenesis of varicella-zoster virus glycoprotein I (gI) identifies a cysteine residue critical for gE/gI heterodimer formation, gI structure, and virulence in skin cells
Q33640129Myelin-associated glycoprotein mediates membrane fusion and entry of neurotropic herpesviruses
Q37256702Regulation of the ORF61 promoter and ORF61 functions in varicella-zoster virus replication and pathogenesis
Q35776521Simian varicella virus gene expression during acute and latent infection of rhesus macaques
Q36145800The varicella-zoster virus genome
Q39214502Varicella-Zoster Virus Glycoproteins: Entry, Replication, and Pathogenesis
Q37547741Varicella-zoster virus ORF49 functions in the efficient production of progeny virus through its interaction with essential tegument protein ORF44

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