Mutational analysis of the role of glycoprotein I in varicella-zoster virus replication and its effects on glycoprotein E conformation and trafficking

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Mutational analysis of the role of glycoprotein I in varicella-zoster virus replication and its effects on glycoprotein E conformation and trafficking is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID192286
P698PubMed publication ID9343180

P2093author name stringA M Arvin
M Sommer
S Mallory
P2860cites workEpitopes functional in neutralization of varicella-zoster virusQ27488400
Folding and assembly of viral membrane proteinsQ27865318
Identification of a novel herpes simplex virus type 1-induced glycoprotein which complexes with gE and binds immunoglobulinQ33720617
Varicella-zoster virus: isolation and propagation in human melanoma cells at 36 and 32 degrees CQ34075139
The complete DNA sequence of varicella-zoster virusQ34162480
A conventionally attenuated glycoprotein E-negative strain of bovine herpesvirus type 1 is an efficacious and safe vaccineQ34329758
Identification of a herpes simplex virus 1 glycoprotein gene within a gene cluster dispensable for growth in cell cultureQ34633054
Varicella-zoster virus gene 63 encodes an immediate-early protein that is abundantly expressed during latencyQ35839306
Tropism of varicella-zoster virus for human CD4+ and CD8+ T lymphocytes and epidermal cells in SCID-hu miceQ35845405
Glycoproteins E and I facilitate neuron-to-neuron spread of herpes simplex virusQ35851060
Glycoprotein D-negative pseudorabies virus can spread transneuronally via direct neuron-to-neuron transmission in its natural host, the pig, but not after additional inactivation of gE or gI.Q35858536
Targeting of glycoprotein I (gE) of varicella-zoster virus to the trans-Golgi network by an AYRV sequence and an acidic amino acid-rich patch in the cytosolic domain of the molecule.Q35869359
Multiple regulatory effects of varicella-zoster virus (VZV) gL on trafficking patterns and fusogenic properties of VZV gH.Q35874201
Varicella-zoster virus Fc receptor gE glycoprotein: serine/threonine and tyrosine phosphorylation of monomeric and dimeric formsQ35874716
Generation of varicella-zoster virus (VZV) and viral mutants from cosmid DNAs: VZV thymidylate synthetase is not essential for replication in vitroQ36465730
Herpes simplex virus glycoproteins E and I facilitate cell-to-cell spread in vivo and across junctions of cultured cellsQ36626714
Varicella-zoster virus glycoprotein gpI/gpIV receptor: expression, complex formation, and antigenicity within the vaccinia virus-T7 RNA polymerase transfection systemQ36639428
Egress of varicella-zoster virus from the melanoma cell: a tropism for the melanocyteQ36687140
Neutralizing antibodies induced by recombinant vaccinia virus expressing varicella-zoster virus gpIVQ36798650
Generation of an inverting herpes simplex virus 1 mutant lacking the L-S junction a sequences, an origin of DNA synthesis, and several genes including those specifying glycoprotein E and the alpha 47 geneQ36862990
A herpes simplex virus mutant in which glycoprotein D sequences are replaced by beta-galactosidase sequences binds to but is unable to penetrate into cellsQ36866557
Complex between glycoproteins gI and gp63 of pseudorabies virus: its effect on virus replication.Q36873883
Structural analysis of the varicella-zoster virus gp98-gp62 complex: posttranslational addition of N-linked and O-linked oligosaccharide moietiesQ36899072
Fc and C3 receptors induced by herpes simplex virus on cultured human endothelial cellsQ37014056
Glycoproteins encoded by varicella-zoster virus: biosynthesis, phosphorylation, and intracellular trafficking.Q37900039
Characteristics of the Fc receptor induced by herpes simplex virusQ39479417
Biosynthesis of glycoproteins E and I of feline herpesvirus: gE-gI interaction is required for intracellular transport.Q39875619
Synthesis, processing, and oligomerization of bovine herpesvirus 1 gE and gI membrane proteins.Q39876906
Adaptability in herpesviruses: glycoprotein D-independent infectivity of pseudorabies virus.Q39877521
Endocytosis and recycling of varicella-zoster virus Fc receptor glycoprotein gE: internalization mediated by a YXXL motif in the cytoplasmic tail.Q39879505
Unusual phosphorylation sequence in the gpIV (gI) component of the varicella-zoster virus gpI-gpIV glycoprotein complex (VZV gE-gI complex).Q40038098
Characterization of domains of herpes simplex virus type 1 glycoprotein E involved in Fc binding activity for immunoglobulin G aggregates.Q40040178
Analysis of the contributions of herpes simplex virus type 1 membrane proteins to the induction of cell-cell fusionQ40042646
Specific pseudorabies virus infection of the rat visual system requires both gI and gp63 glycoproteins.Q40045763
Identification of the phosphorylation sequence in the cytoplasmic tail of the varicella-zoster virus Fc receptor glycoprotein gpI.Q40046272
Specific lysis of targets expressing varicella-zoster virus gpI or gpIV by CD4+ human T-cell clonesQ40065177
Pseudorabies virus envelope glycoprotein gI influences both neurotropism and virulence during infection of the rat visual systemQ40065416
Receptor properties of two varicella-zoster virus glycoproteins, gpI and gpIV, homologous to herpes simplex virus gE and gIQ40065898
Regeneration of herpesviruses from molecularly cloned subgenomic fragmentsQ40128343
A tyrosine-based motif and a casein kinase II phosphorylation site regulate the intracellular trafficking of the varicella-zoster virus glycoprotein I, a protein localized in the trans-Golgi networkQ41078474
Purification, characterization and immunogenicity of recombinant varicella-zoster virus glycoprotein gE secreted by Chinese hamster ovary cellsQ41232293
An analysis of the in vitro and in vivo phenotypes of mutants of herpes simplex virus type 1 lacking glycoproteins gG, gE, gI or the putative gJ.Q41462238
The equine herpesvirus type 1 (EHV-1) homolog of herpes simplex virus type 1 US9 and the nature of a major deletion within the unique short segment of the EHV-1 KyA strain genomeQ42600064
Humoral and cellular immunity to varicella-zoster virus glycoprotein gpI and to a non-glycosylated protein, p170, in the strain 2 guinea-pigQ43631571
Fc receptors induced by herpes simplex virus. I. Biologic and biochemical propertiesQ44298097
Deletion of glycoprotein gE reduces the propagation of pseudorabies virus in the nervous system of mice after intranasal inoculationQ45770990
Characterization of a Marek's disease virus mutant containing a lacZ insertion in the US6 (gD) homologue geneQ45783866
The synthesis of glycoproteins in human melanoma cells infected with varicella-zoster virusQ45803938
Identification of the products of a varicella-zoster virus glycoprotein geneQ45838080
Evolutionary relationships of virion glycoprotein genes in the S regions of alphaherpesvirus genomesQ68484206
Immunity to varicella-zoster viral glycoproteins, gp I (gp 90/58) and gp III (gp 118), and to a nonglycosylated protein, p 170Q70144469
Live attenuated varicella vaccineQ71752095
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectmutational analysisQ1955810
P1104number of pages10
P304page(s)8279-8288
P577publication date1997-11-01
P1433published inJournal of VirologyQ1251128
P1476titleMutational analysis of the role of glycoprotein I in varicella-zoster virus replication and its effects on glycoprotein E conformation and trafficking
P478volume71

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cites work (P2860)
Q40072508A self-excisable infectious bacterial artificial chromosome clone of varicella-zoster virus allows analysis of the essential tegument protein encoded by ORF9.
Q35956960Aberrant infection and persistence of varicella-zoster virus in human dorsal root ganglia in vivo in the absence of glycoprotein I.
Q36099097Cellular and viral factors regulate the varicella-zoster virus gE promoter during viral replication
Q39550597Characterization of Varicella-Zoster virus glycoprotein K (open reading frame 5) and its role in virus growth
Q39685724Comparison of the complete DNA sequences of the Oka varicella vaccine and its parental virus
Q34434777Comparison of virus transcription during lytic infection of the Oka parental and vaccine strains of Varicella-Zoster virus
Q39642417Complex formation facilitates endocytosis of the varicella-zoster virus gE:gI Fc receptor.
Q34977139Construction of varicella-zoster virus recombinants from parent Oka cosmids and demonstration that ORF65 protein is dispensable for infection of human skin and T cells in the SCID-hu mouse model
Q37033241Deletion of the first cysteine-rich region of the varicella-zoster virus glycoprotein E ectodomain abolishes the gE and gI interaction and differentially affects cell-cell spread and viral entry
Q43161154Development of recombinant varicella-zoster viruses expressing luciferase fusion proteins for live in vivo imaging in human skin and dorsal root ganglia xenografts
Q37596465Differential requirement for cell fusion and virion formation in the pathogenesis of varicella-zoster virus infection in skin and T cells
Q90714289Duck plague virus gE serves essential functions during the virion final envelopment through influence capsids budding into the cytoplasmic vesicles
Q30832346Dysregulated Glycoprotein B-Mediated Cell-Cell Fusion Disrupts Varicella-Zoster Virus and Host Gene Transcription during Infection
Q35101360Essential functions of the unique N-terminal region of the varicella-zoster virus glycoprotein E ectodomain in viral replication and in the pathogenesis of skin infection
Q39601211Essential role played by the C-terminal domain of glycoprotein I in envelopment of varicella-zoster virus in the trans-Golgi network: interactions of glycoproteins with tegument
Q41482036Felid herpesvirus type 1 infection in cats: a natural host model for alphaherpesvirus pathogenesis
Q37596576Functions of the C-terminal domain of varicella-zoster virus glycoprotein E in viral replication in vitro and skin and T-cell tropism in vivo
Q33591823Functions of the unique N-terminal region of glycoprotein E in the pathogenesis of varicella-zoster virus infection
Q40117236Genetic analysis of varicella-zoster virus ORF0 to ORF4 by use of a novel luciferase bacterial artificial chromosome system
Q28474768Genome-wide mutagenesis reveals that ORF7 is a novel VZV skin-tropic factor
Q37065966Global Mapping of O-Glycosylation of Varicella Zoster Virus, Human Cytomegalovirus, and Epstein-Barr Virus.
Q40843597Glycoprotein E of varicella-zoster virus enhances cell-cell contact in polarized epithelial cells
Q39753125Glycoprotein I of varicella-zoster virus is required for viral replication in skin and T cells
Q39605251Glycoproteins E and I of Marek's disease virus serotype 1 are essential for virus growth in cultured cells
Q34499618Herpesvirus assembly and egress
Q24522734High-level expression of Marek's disease virus glycoprotein C is detrimental to virus growth in vitro
Q48172861In the absence of glycoprotein I (gI), gE determines bovine herpesvirus type 5 neuroinvasiveness and neurovirulence
Q40478161Incorporation of three endocytosed varicella-zoster virus glycoproteins, gE, gH, and gB, into the virion envelope
Q33622464Insulin degrading enzyme induces a conformational change in varicella-zoster virus gE, and enhances virus infectivity and stability
Q37633252Interaction of allergy history and antibodies to specific varicella-zoster virus proteins on glioma risk
Q33639421Intracellular traffic of herpes simplex virus glycoprotein gE: characterization of the sorting signals required for its trans-Golgi network localization.
Q36171893Marek's disease virus expresses multiple UL44 (gC) variants through mRNA splicing that are all required for efficient horizontal transmission
Q30531746Microarray analysis of host cell gene transcription in response to varicella-zoster virus infection of human T cells and fibroblasts in vitro and SCIDhu skin xenografts in vivo
Q33791387Molecular mechanisms of varicella zoster virus pathogenesis
Q35076854Mutagenesis of varicella-zoster virus glycoprotein I (gI) identifies a cysteine residue critical for gE/gI heterodimer formation, gI structure, and virulence in skin cells
Q34977329Mutational Analysis of Open Reading Frames 62 and 71, Encoding the Varicella-Zoster Virus Immediate-Early Transactivating Protein, IE62, and Effects on Replication In Vitro and in Skin Xenografts in the SCID-hu Mouse In Vivo
Q33853728Mutational analysis of the repeated open reading frames, ORFs 63 and 70 and ORFs 64 and 69, of varicella-zoster virus
Q34434911Mutational analysis of the varicella-zoster virus ORF62/63 intergenic region
Q33640129Myelin-associated glycoprotein mediates membrane fusion and entry of neurotropic herpesviruses
Q35139995ORF66 protein kinase function is required for T-cell tropism of varicella-zoster virus in vivo
Q35000306Physical interaction between envelope glycoproteins E and M of pseudorabies virus and the major tegument protein UL49.
Q39698466Promoter sequences of varicella-zoster virus glycoprotein I targeted by cellular transactivating factors Sp1 and USF determine virulence in skin and T cells in SCIDhu mice in vivo
Q36890186Requirement of Varicella-Zoster Virus Immediate-Early 4 Protein for Viral Replication
Q39550665Retrograde, transneuronal spread of pseudorabies virus in defined neuronal circuitry of the rat brain is facilitated by gE mutations that reduce virulence.
Q39686119Role of the varicella-zoster virus gB cytoplasmic domain in gB transport and viral egress
Q33724286Role of the varicella-zoster virus gene product encoded by open reading frame 35 in viral replication in vitro and in differentiated human skin and T cells in vivo
Q35776521Simian varicella virus gene expression during acute and latent infection of rhesus macaques
Q34045556T-cell tropism and the role of ORF66 protein in pathogenesis of varicella-zoster virus infection
Q36327713The ORF47 and ORF66 putative protein kinases of varicella-zoster virus determine tropism for human T cells and skin in the SCID-hu mouse
Q35947774The amino terminus of varicella-zoster virus (VZV) glycoprotein E is required for binding to insulin-degrading enzyme, a VZV receptor
Q39580163The disulfide-bonded structure of feline herpesvirus glycoprotein I.
Q33987514The extracellular domain of herpes simplex virus gE is indispensable for efficient cell-to-cell spread: evidence for gE/gI receptors
Q33785316The herpes simplex virus gE-gI complex facilitates cell-to-cell spread and binds to components of cell junctions
Q35543796The immediate-early 63 protein of Varicella-Zoster virus: analysis of functional domains required for replication in vitro and for T-cell and skin tropism in the SCIDhu model in vivo.
Q33554456The insulin degrading enzyme binding domain of varicella-zoster virus (VZV) glycoprotein E is important for cell-to-cell spread and VZV infectivity, while a glycoprotein I binding domain is essential for infection
Q36145800The varicella-zoster virus genome
Q39592132Trafficking of varicella-zoster virus glycoprotein gI: T(338)-dependent retention in the trans-Golgi network, secretion, and mannose 6-phosphate-inhibitable uptake of the ectodomain
Q39685893Tropism of varicella-zoster virus for human tonsillar CD4(+) T lymphocytes that express activation, memory, and skin homing markers
Q35054349Varicella zoster virus latency
Q39214502Varicella-Zoster Virus Glycoproteins: Entry, Replication, and Pathogenesis
Q36474261Varicella-Zoster Virus ORF47 Protein Kinase, Which Is Required for Replication in Human T Cells, and ORF66 Protein Kinase, Which Is Expressed during Latency, Are Dispensable for Establishment of Latency
Q33833934Varicella-Zoster virus pathogenesis and immunobiology: new concepts emerging from investigations with the SCIDhu mouse model
Q33641265Varicella-zoster virus Fc receptor component gI is phosphorylated on its endodomain by a cyclin-dependent kinase
Q33828495Varicella-zoster virus T cell tropism and the pathogenesis of skin infection
Q34457924Varicella-zoster virus glycoprotein E is a critical determinant of virulence in the SCID mouse-human model of neuropathogenesis
Q37336873Varicella-zoster virus glycoprotein I is essential for spread in dorsal root ganglia and facilitates axonal localization of structural virion components in neuronal cultures
Q33704274Varicella-zoster virus human ganglionic latency: a current summary
Q34545651Varicella-zoster virus open reading frame 10 is a virulence determinant in skin cells but not in T cells in vivo
Q28363307Varicella-zoster virus retains major histocompatibility complex class I proteins in the Golgi compartment of infected cells