Activatable magnetic resonance imaging agents for myeloperoxidase sensing: mechanism of activation, stability, and toxicity

scientific article

Activatable magnetic resonance imaging agents for myeloperoxidase sensing: mechanism of activation, stability, and toxicity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1021/JA905274F
P932PMC publication ID2802665
P698PubMed publication ID19968300
P5875ResearchGate publication ID40455217

P50authorRalph WeisslederQ7288259
P2093author name stringJohn W Chen
Elisenda Rodríguez
Mark Nilges
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The synthesis and in vitro testing of a zinc-activated MRI contrast agentQ31122779
Mechanisms of ZnII-activated magnetic resonance imaging agentsQ33377534
Bioresponsive, cell-penetrating, and multimeric MR contrast agentsQ33470566
Myeloperoxidase-targeted imaging of active inflammatory lesions in murine experimental autoimmune encephalomyelitisQ33708751
Consequences of total and subtotal myeloperoxidase deficiency: risk or benefit ?Q33927624
Association between myeloperoxidase levels and risk of coronary artery diseaseQ34100405
Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesionsQ34236265
Prognostic value of myeloperoxidase in patients with chest painQ34271813
Growing significance of myeloperoxidase in non-infectious diseases.Q34578402
Tyrosyl radical production by myeloperoxidase: a phagocyte pathway for lipid peroxidation and dityrosine cross-linking of proteinsQ34749406
Immunohistochemical detection of myeloperoxidase and its oxidation products in Kupffer cells of human liverQ35747219
Imaging of myeloperoxidase in mice by using novel amplifiable paramagnetic substratesQ36545615
Oxidative stress, lipid rafts, and macrophage reprogrammingQ36885673
Tracking the inflammatory response in stroke in vivo by sensing the enzyme myeloperoxidaseQ36985114
Inhibition of reactive oxygen species down-regulates protein synthesis in RAW 264.7.Q39981131
Serum myeloperoxidase levels are associated with the future risk of coronary artery disease in apparently healthy individuals: the EPIC-Norfolk Prospective Population StudyQ40196845
Activatable magnetic resonance imaging agent reports myeloperoxidase activity in healing infarcts and noninvasively detects the antiinflammatory effects of atorvastatin on ischemia-reperfusion injury.Q41864110
Enzyme-sensitive magnetic resonance imaging targeting myeloperoxidase identifies active inflammation in experimental rabbit atherosclerotic plaquesQ42543316
Kinetic evidence for rapid oxidation of (-)-epicatechin by human myeloperoxidaseQ43441240
Redox properties of the couples compound I/compound II and compound II/native enzyme of human myeloperoxidaseQ44301559
Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell killQ44302226
Neuronal expression of myeloperoxidase is increased in Alzheimer's diseaseQ44980217
Ablation of the inflammatory enzyme myeloperoxidase mitigates features of Parkinson's disease in mice.Q45297626
Immunohistochemical and genetic evidence of myeloperoxidase involvement in multiple sclerosisQ48615832
Plasma lipoperoxidative markers in ischaemic stroke suggest brain embolismQ48772351
Differentiation of human monocytes in bone marrow and blood. Sequential formation of two granule populationsQ54462461
Lanthanide-Loaded Paramagnetic Liposomes as Switchable Magnetically Oriented NanovesiclesQ58830297
Further evidence for the role of myeloperoxidase in the activation of benzo[a]pyrene-7,8-dihydrodiol by polymorphonuclear leukocytesQ68244401
Antimicrobial activity of myeloperoxidaseQ70214734
A functional myeloperoxidase polymorphic variant is associated with coronary artery disease in French-CanadiansQ74293599
Electron paramagnetic resonance detection of free tyrosyl radical generated by myeloperoxidase, lactoperoxidase, and horseradish peroxidaseQ77580985
Contribution of myeloperoxidase to coronary artery vasculitis associated with MPO-ANCA productionQ77604789
Elevated activity and microglial expression of myeloperoxidase in demyelinated cerebral cortex in multiple sclerosisQ80089503
Kinetics of phenolic polymerization catalyzed by peroxidase in organic mediaQ81633235
DTPA-bisamide-based MR sensor agents for peroxidase imagingQ81674771
A paramagnetic contrast agent with myeloperoxidase-sensing propertiesQ83318371
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)168-177
P577publication date2010-01-01
P1433published inJournal of the American Chemical SocietyQ898902
P1476titleActivatable magnetic resonance imaging agents for myeloperoxidase sensing: mechanism of activation, stability, and toxicity
P478volume132

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