Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions

scientific article

Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1172/JCI117342
P932PMC publication ID296328
P698PubMed publication ID8040285

P2093author name stringA Daugherty
J W Heinecke
J L Dunn
D L Rateri
P2860cites workProtein measurement with the Folin phenol reagentQ20900776
Specific inflammatory cytokines regulate the expression of human monocyte 15-lipoxygenaseQ24563459
Tyrosyl radical generated by myeloperoxidase catalyzes the oxidative cross-linking of proteinsQ24564612
Biological reactivity of hypochlorous acid: implications for microbicidal mechanisms of leukocyte myeloperoxidaseQ24635143
Studies on the chlorinating activity of myeloperoxidaseQ28235493
Evidence for a dominant role of lipoxygenase(s) in the oxidation of LDL by mouse peritoneal macrophagesQ28303116
Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and manQ28359675
Probucol attenuates the development of aortic atherosclerosis in cholesterol-fed rabbitsQ28359752
Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol depositionQ28625661
The pathogenesis of atherosclerosis: a perspective for the 1990sQ29547827
Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicityQ29617216
Minimally modified low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cellsQ33667974
Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesionsQ33783079
A role for endothelial cell lipoxygenase in the oxidative modification of low density lipoproteinQ33836010
Low density lipoprotein undergoes oxidative modification in vivoQ33838672
Phagocytosis of aggregated lipoprotein by macrophages: low density lipoprotein receptor-dependent foam-cell formationQ33850346
Myeloperoxidase-mediated inhibition of microbial respiration: damage to Escherichia coli ubiquinol oxidaseQ34042575
Chlorohydrin formation from unsaturated fatty acids reacted with hypochlorous acidQ34236440
Minimally modified low density lipoprotein stimulates monocyte endothelial interactionsQ34248823
Cellular oxidation of low density lipoprotein is caused by thiol production in media containing transition metal ions.Q34335341
Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemiaQ34340579
Antiatherogenic effect of probucol unrelated to its hypocholesterolemic effect: evidence that antioxidants in vivo can selectively inhibit low density lipoprotein degradation in macrophage-rich fatty streaks and slow the progression of atherosclerosQ34360883
Oxygen-dependent microbial killing by phagocytes (first of two parts).Q34381571
Lipid peroxidation by human blood phagocytesQ34466556
Cell biology of arterial proteoglycans.Q34496708
Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agentQ34501431
Superoxide-mediated modification of low density lipoprotein by arterial smooth muscle cellsQ34526444
Iron and copper promote modification of low density lipoprotein by human arterial smooth muscle cells in cultureQ34620804
Direct evidence for a protein recognized by a monoclonal antibody against oxidatively modified LDL in atherosclerotic lesions from a Watanabe heritable hyperlipidemic rabbit.Q35817369
A human macrophage-associated antigen (CD68) detected by six different monoclonal antibodiesQ36236863
Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipidsQ36263522
Specificity of receptor-mediated recognition of malondialdehyde-modified low density lipoproteinsQ36286282
Enhanced macrophage degradation of low density lipoprotein previously incubated with cultured endothelial cells: recognition by receptors for acetylated low density lipoproteinsQ36376146
Oxidative tyrosylation of high density lipoprotein by peroxidase enhances cholesterol removal from cultured fibroblasts and macrophage foam cellsQ36423053
Cellular oxidative modification of low density lipoprotein does not require lipoxygenasesQ36759839
Hydrogen peroxide metabolism in human monocytes during differentiation in vitroQ37005256
Unique autolytic cleavage of human myeloperoxidase. Implications for the involvement of active site MET409Q38323385
Myeloperoxidase deficiencyQ39184783
Characterization and quantification of the peroxidase in human monocytesQ39207271
The pathogenesis of atherosclerosis--an updateQ39726917
The subunit structure of crystalline canine myeloperoxidaseQ40089133
Oxygen Metabolism and the Toxic Properties of PhagocytesQ40122453
Isolation procedure and some properties of myeloperoxidase from human leucocytesQ40150278
Low density lipoprotein is protected from oxidation and the progression of atherosclerosis is slowed in cholesterol-fed rabbits by the antioxidant N,N'-diphenyl-phenylenediamineQ40343733
Minimally oxidized low-density lipoprotein induces tissue factor expression in cultured human endothelial cellsQ41873727
Induction of T-cell activation by oxidized low density lipoproteinQ41940298
HHF35, a muscle-actin-specific monoclonal antibody. I. Immunocytochemical and biochemical characterizationQ42050958
The effects of probucol on the progression of atherosclerosis in mature Watanabe heritable hyperlipidaemic rabbitsQ42115451
Oxidation of low-density lipoprotein with hypochlorite causes transformation of the lipoprotein into a high-uptake form for macrophagesQ42796812
5-Lipoxygenase is not essential in macrophage-mediated oxidation of low-density lipoproteinQ42862580
Malondialdehyde-altered protein occurs in atheroma of Watanabe heritable hyperlipidemic rabbitsQ43652291
Clearance of neutrophil-derived myeloperoxidase by the macrophage mannose receptorQ44775588
Distribution of oxidation specific lipid-protein adducts and apolipoprotein B in atherosclerotic lesions of varying severity from WHHL rabbitsQ46491747
Oxidant membrane injury by the neutrophil myeloperoxidase system. II. Injury by stimulated neutrophils and protection by lipid-soluble antioxidants.Q46590104
Dityrosine, a specific marker of oxidation, is synthesized by the myeloperoxidase-hydrogen peroxide system of human neutrophils and macrophages.Q54247314
Spin trapping evidence for myeloperoxidase-dependent hydroxyl radical formation by human neutrophils and monocytesQ54301272
Myeloperoxidase-catalyzed incorporation of amines into proteins: role of hypochlorous acid and dichloraminesQ67253835
Peroxidase activity in monocytes and tissue macrophages of miceQ67325651
Possible involvement of myeloperoxidase in lipid peroxidationQ67488286
Modification of low density lipoproteins by sodium hypochloriteQ67709484
Intracellular singlet oxygen generation by phagocytosing neutrophils in response to particles coated with a chemical trapQ67852245
Isolation of low density lipoprotein from atherosclerotic vascular tissue of Watanabe heritable hyperlipidemic rabbitsQ67976682
Macrophage oxidation of low density lipoprotein generates a modified form recognized by the scavenger receptorQ69635952
CD antigens 1989Q69693094
Role of superoxide in endothelial-cell modification of low-density lipoproteinsQ69819973
Monocytes and neutrophils oxidize low density lipoprotein making it cytotoxicQ69843470
Evidence for and partial characterization of three major and three minor chromatographic forms of human neutrophil myeloperoxidaseQ70139453
Crystallization and properties of myeloperoxidase from normal human leukocytesQ70140290
Superoxide initiates oxidation of low density lipoprotein by human monocytesQ70164653
Loss of granule myeloperoxidase during in vitro culture of human monocytes correlates with decay in antiprotozoa activityQ70177765
Antimicrobial activity of myeloperoxidaseQ70214734
Oxidation of human low density lipoprotein results in derivatization of lysine residues of apolipoprotein B by lipid peroxide decomposition productsQ70328162
Endothelial and smooth muscle cells alter low density lipoprotein in vitro by free radical oxidationQ70580559
Myeloperoxidase of human leukaemic leucocytes. Oxidation of amino acids in the presence of hydrogen peroxideQ70940747
The reductive cleavage of myeloperoxidase in half, producing enzymically active hemi-myeloperoxidaseQ72887450
Human eosinophil peroxidase: a novel isolation procedure, spectral properties and chlorinating activityQ72890756
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectlipoproteinQ28350
atherosclerosisQ12252367
P304page(s)437-444
P577publication date1994-07-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleMyeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions
P478volume94

Reverse relations

cites work (P2860)
Q373642582-Chlorohexadecanal and 2-chlorohexadecanoic acid induce COX-2 expression in human coronary artery endothelial cells
Q373662883-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima
Q280832603-nitrotyrosine modified proteins in atherosclerosis
Q445882128-Nitroxanthine, a product of myeloperoxidase, peroxynitrite, and activated human neutrophils, enhances generation of superoxide by xanthine oxidase
Q89228322A BODIPY Based Fluorescent Probe for the Rapid Detection of Hypochlorite
Q36250228A Highly Expressed Human Protein, Apolipoprotein B-100, Serves as an Autoantigen in a Subgroup of Patients With Lyme Disease
Q37669759A Janus Chelator Enables Biochemically Responsive MRI Contrast with Exceptional Dynamic Range
Q46639428A Ratiometric Fluorescent Probe Based on a Through-Bond Energy Transfer (TBET) System for Imaging HOCl in Living Cells
Q35562004A biochemical fluorometric method for assessing the oxidative properties of HDL.
Q38930883A fast-responsive mitochondria-targeted fluorescent probe detecting endogenous hypochlorite in living RAW 264.7 cells and nude mouse
Q53220935A fluorescent probe for hypochlorite based on the modulation of the unique rotation of the N-N single bond in acetohydrazide.
Q42679591A fluorescent probe for the detection of myeloperoxidase activity in atherosclerosis-associated macrophages
Q45731096A genotypic association implicates myeloperoxidase in the progression of hepatic fibrosis in chronic hepatitis C virus infection
Q28544713A high throughput biochemical fluorometric method for measuring lipid peroxidation in HDL
Q36039153A highly selective and sensitive photoinduced electron transfer (PET) based HOCl fluorescent probe in water and its endogenous imaging in living cells
Q58860182A highly sensitive and rapidly responding fluorescent probe based on a rhodol fluorophore for imaging endogenous hypochlorite in living mice
Q46592840A highly specific BODIPY-based probe localized in mitochondria for HClO imaging
Q52723580A myeloperoxidase precursor, pro-myeloperoxidase, is present in human plasma and elevated in cardiovascular disease patients.
Q40637446A novel method of following oxidation of low-density lipoprotein using a sensitive fluorescent probe, diphenyl-1-pyrenylphosphine
Q39158525A ratiometric fluorescent probe based on a BODIPY-DCDHF conjugate for the detection of hypochlorous acid in living cells
Q38898049A ratiometric fluorescent probe for in situ quantification of basal mitochondrial hypochlorite in cancer cells.
Q39868162A reconstituted HDL containing V156K or R173C apoA-I exhibited anti-inflammatory activity in apo-E deficient mice and showed resistance to myeloperoxidase-mediated oxidation
Q37089128A sensitive and specific ELISA detects methionine sulfoxide-containing apolipoprotein A-I in HDL.
Q50202617A tumor-specific and mitochondria-targeted fluorescent probe for real-time sensing of hypochlorite in living cells
Q35044854A1M/α1-microglobulin is proteolytically activated by myeloperoxidase, binds its heme group and inhibits low density lipoprotein oxidation
Q36192289ABCA1 and atherosclerosis.
Q45297626Ablation of the inflammatory enzyme myeloperoxidase mitigates features of Parkinson's disease in mice.
Q33222417Acrolein impairs ATP binding cassette transporter A1-dependent cholesterol export from cells through site-specific modification of apolipoprotein A-I.
Q40394753Acrolein modifies apolipoprotein A-I in the human artery wall
Q33575669Activatable magnetic resonance imaging agents for myeloperoxidase sensing: mechanism of activation, stability, and toxicity
Q36906145Activation and silencing of matrix metalloproteinases
Q38052020Advances in molecular imaging of atherosclerosis and myocardial infarction: shedding new light on in vivo cardiovascular biology.
Q31060150Albumin mediates the transcytosis of myeloperoxidase by means of caveolae in endothelial cells
Q46710488Allopurinol improves endothelial function and reduces oxidant-inflammatory enzyme of myeloperoxidase in metabolic syndrome
Q36493881Alpha-chlorofatty Acid and coronary artery or aorta calcium scores in women with systemic lupus erythematosus. A pilot study.
Q38260171Alpha-chlorofatty acid accumulates in activated monocytes and causes apoptosis through reactive oxygen species production and endoplasmic reticulum stress
Q73762580Alpha-tocopherol does not inhibit hypochlorite-induced oxidation of apolipoprotein B-100 of low-density lipoprotein
Q84752654Aminobenzoic acid hydrazide, a myeloperoxidase inhibitor, alters the adhesive properties of neutrophils isolated from acute myocardial infarction patients
Q34543361An effective and rapid determination by MALDI/TOF/TOF of methionine sulphoxide content of ApoA-I in type 2 diabetic patients.
Q35466129An oxygen-induced but protein F-independent fibronectin-binding pathway in Streptococcus pyogenes.
Q36610126Anti-inflammatory agents and monoHER protect against DOX-induced cardiotoxicity and accumulation of CML in mice
Q48969142Antibodies against adhesion molecules reduce apoptosis after transient middle cerebral artery occlusion in rat brain
Q28283086Antimicrobial reactive oxygen and nitrogen species: concepts and controversies
Q35757158ApoA-1 in Diabetes: Damaged Goods
Q37286296Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease
Q40637436Apoptotic pathways involved in U937 cells exposed to LDL oxidized by hypochlorous acid
Q36926660Assessing Human Health Risk to Endocrine Disrupting Chemicals: a Focus on Prenatal Exposures and Oxidative Stress
Q37608445Assessment of myeloperoxidase activity by the conversion of hydroethidine to 2-chloroethidium
Q42251021Association between serum myeloperoxidase levels and coronary artery disease in patients without diabetes, hypertension, obesity, and hyperlipidemia
Q50997002Association of biomarkers of lipid modification with functional and morphological indices of coronary stenosis severity in stable coronary artery disease.
Q42215707Association of heme oxygenase 1 with the restoration of liver function after damage in murine malaria by Plasmodium yoelii
Q47878722Association of myeloperoxidase with heparin: oxidative inactivation of proteins on the surface of endothelial cells by the bound enzyme
Q37364334Association of serum myeloperoxidase with the ankle-brachial index and peripheral arterial disease
Q37172222Association of serum osteoprotegerin with ankle-brachial index and urine albumin: creatinine ratio in African-Americans and non-Hispanic whites
Q50927115Association of the serum myeloperoxidase/high-density lipoprotein particle ratio and incident cardiovascular events in a multi-ethnic population: Observations from the Dallas Heart Study.
Q40418236Atherosclerosis, oxidative stress, and antioxidant protection in endothelium-derived relaxing factor action
Q41829508Attenuation of diet-induced atherosclerosis in rabbits with a highly selective 15-lipoxygenase inhibitor lacking significant antioxidant properties
Q60924320Bases celulares y moleculares de la acumulación de colesterol en la pared vascular y su contribución a la progresión de la lesión aterosclerótica
Q73072515Beta-blockers inhibit the modification of low-density lipoproteins by sodium hypochlorite in vitro
Q92782717Binding of myeloperoxidase to the extracellular matrix of smooth muscle cells and subsequent matrix modification
Q36780282Biochemical and pathological studies on peroxidases -an updated review
Q37313946Biological markers of oxidative stress: Applications to cardiovascular research and practice
Q60924187Biología celular y molecular de las lesiones ateroscleróticas
Q34054210Biomarkers of myeloperoxidase-derived hypochlorous acid
Q41154272Blood radicals: reactive nitrogen species, reactive oxygen species, transition metal ions, and the vascular system
Q34310448Cardiovascular disease and nutrient antioxidants: role of low-density lipoprotein oxidation
Q46230315Ceruloplasmin and myeloperoxidase in complex affect the enzymatic properties of each other
Q38344922Characterization and antioxidant properties of six Algerian propolis extracts: ethyl acetate extracts inhibit myeloperoxidase activity
Q32062976Characterization of peroxynitrite-oxidized low density lipoprotein binding to human CD36.
Q37549646Chlorinated Phospholipids and Fatty Acids: (Patho)physiological Relevance, Potential Toxicity, and Analysis of Lipid Chlorohydrins
Q33784503Chlorinated lipid species in activated human neutrophils: lipid metabolites of 2-chlorohexadecanal
Q58762763Chlorination and oxidation of human plasma fibronectin by myeloperoxidase-derived oxidants, and its consequences for smooth muscle cell function
Q59807449Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase
Q46256505Chlorinative stress in age-related diseases: a literature review
Q34074664Chlorotyrosine promotes human aortic smooth muscle cell migration through increasing superoxide anion production and ERK1/2 activation
Q46689320Citrate anticoagulation abolishes degranulation of polymorphonuclear cells and platelets and reduces oxidative stress during haemodialysis
Q43655175Citrus flavanones affect hepatic fatty acid oxidation in rats by acting as prooxidant agents
Q26785512Clinical Relevance of Biomarkers of Oxidative Stress
Q33598770Clinical significance of the humoral immune response to modified LDL.
Q35062312Clinical trials of vitamin E in coronary artery disease: is it time to reconsider the low-density lipoprotein oxidation hypothesis?
Q35153774Clonal analysis of hematopoietic progenitor cells in the zebrafish
Q37358413Cloning of monoclonal autoantibodies to epitopes of oxidized lipoproteins from apolipoprotein E-deficient mice. Demonstration of epitopes of oxidized low density lipoprotein in human plasma
Q47739511Colocalization of iron and ceroid in human atherosclerotic lesions
Q72999605Comparison of HOCl traps with myeloperoxidase inhibitors in prevention of low density lipoprotein oxidation
Q77161290Correlation between intima-to-media ratio, apolipoprotein B-100, myeloperoxidase, and hypochlorite-oxidized proteins in human atherosclerosis
Q62125033Cross-sectional correlates of myeloperoxidase and alpha-1-acid glycoprotein with adiposity, atherogenic and hematological indices in metabolic syndrome patients with or without diabetes
Q77907848Detecting oxidative modification of biomolecules with isotope dilution mass spectrometry: sensitive and quantitative assays for oxidized amino acids in proteins and tissues
Q43002718Detection of HOCl-mediated protein oxidation products in the extracellular matrix of human atherosclerotic plaques
Q46611633Development and sensing applications of fluorescent motifs within the mitochondrial environment
Q59704191Different apolipoprotein B breakdown patterns in models of oxidized low density lipoprotein
Q90092715Differential effects of Th17 cytokines during the response of neutrophils to Burkholderia cenocepacia outer membrane protein A
Q46796686Differential effects of chlorinated and oxidized phospholipids in vascular tissue: implications for neointima formation
Q34342725Differential microRNA response to a high-cholesterol, high-fat diet in livers of low and high LDL-C baboons
Q34758389Distinct HDL subclasses present similar intrinsic susceptibility to oxidation by HOCl.
Q41528800Distinct infiltration of neutrophils in lesion shoulders in ApoE-/- mice.
Q41432893Does an acidic pH explain why low density lipoprotein is oxidised in atherosclerotic lesions?
Q39859430Dose-dependent transitions in Nrf2-mediated adaptive response and related stress responses to hypochlorous acid in mouse macrophages
Q35167895Dual functionality of myeloperoxidase in rotenone-exposed brain-resident immune cells.
Q38577283Dysfunctional HDL and atherosclerotic cardiovascular disease
Q33604003Dysfunctional HDL as a diagnostic and therapeutic target
Q26774903Dysfunctional High-Density Lipoprotein: An Innovative Target for Proteomics and Lipidomics
Q28287127Effect of a short-term diet and exercise intervention on oxidative stress, inflammation, MMP-9, and monocyte chemotactic activity in men with metabolic syndrome factors
Q43964246Effect of acetaminophen on the myeloperoxidase-hydrogen peroxide-nitrite mediated oxidation of LDL.
Q50913860Effect of ascophyllan from brown algae Padina tetrastromatica on inflammation and oxidative stress in carrageenan-induced rats.
Q34515851Effects of a novel pharmacologic inhibitor of myeloperoxidase in a mouse atherosclerosis model
Q37301032Effects of copper sulfate-oxidized or myeloperoxidase-modified LDL on lipid loading and programmed cell death in macrophages under hypoxia
Q43777199Effects of hypochlorous acid on unsaturated phosphatidylcholines
Q46012541Effects of timed administration of doxycycline or methylprednisolone on post-myocardial infarction inflammation and left ventricular remodeling in the rat heart.
Q28344995Elevated levels of protein-bound p-hydroxyphenylacetaldehyde, an amino-acid-derived aldehyde generated by myeloperoxidase, are present in human fatty streaks, intermediate lesions and advanced atherosclerotic lesions
Q33723943Elevated plasma free fatty acids increase cardiovascular risk by inducing plasma biomarkers of endothelial activation, myeloperoxidase and PAI-1 in healthy subjects
Q89775678Emerging Associations Between Neutrophils, Atherosclerosis, and Psoriasis
Q28366645Endothelial transcytosis of myeloperoxidase confers specificity to vascular ECM proteins as targets of tyrosine nitration
Q73176780Endothelium-dependent relaxation of rabbit atherosclerotic aorta was not restored by control of hyperlipidemia: the possible role of peroxynitrite (ONOO(-))
Q46540013Enhanced Fluorescence Turn-on Imaging of Hypochlorous Acid in Living Immune and Cancer Cells
Q24311407Enhanced cholesterol efflux by tyrosyl radical-oxidized high density lipoprotein is mediated by apolipoprotein AI-AII heterodimers
Q33816483Enhanced tyrosine nitration of prostacyclin synthase is associated with increased inflammation in atherosclerotic carotid arteries from type 2 diabetic patients
Q42543316Enzyme-sensitive magnetic resonance imaging targeting myeloperoxidase identifies active inflammation in experimental rabbit atherosclerotic plaques
Q33919164Eosinophil-dependent bromination in the pathogenesis of asthma
Q90055412Evaluation of reproductive and renal toxicity of varenicline in male rats
Q43200073Evaluation of the cardiovascular effects of varenicline in rats.
Q42991232Evidence for roles of radicals in protein oxidation in advanced human atherosclerotic plaque
Q41842014Evidence of inflammatory cell involvement in brain arteriovenous malformations
Q33897950Exchange of apolipoprotein A-I between lipid-associated and lipid-free states: a potential target for oxidative generation of dysfunctional high density lipoproteins
Q40030728Exposure of aconitase to smoking-related oxidants results in iron loss and increased iron response protein-1 activity: potential mechanisms for iron accumulation in human arterial cells
Q34313976Exposure of endothelial cells to physiological levels of myeloperoxidase-modified LDL delays pericellular fibrinolysis
Q91661911Feasibility of a plasma bioassay to assess oxidative protection of low-density lipoproteins by high-density lipoproteins
Q45811598Fluorescent hydroxylamine derived from the fragmentation of PAMAM dendrimers for intracellular hypochlorite recognition.
Q30743600Formation of lysophospholipids from unsaturated phosphatidylcholines under the influence of hypochlorous acid
Q46943421Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils
Q41978147Fragmentation of extracellular matrix by hypochlorous acid
Q37894551Generation and detection of levuglandins and isolevuglandins in vitro and in vivo.
Q36461073Genetic markers of oxidative stress and coronary atherosclerosis
Q38311723Genetic variants of myeloperoxidase and lung cancer risk
Q40137109Glycation of low-density lipoprotein results in the time-dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages
Q34578402Growing significance of myeloperoxidase in non-infectious diseases.
Q35120941HDL from apoA1 transgenic mice expressing the 4WF isoform is resistant to oxidative loss of function
Q37367671HDL, lipid peroxidation, and atherosclerosis
Q28535779HDL-apoA-I exchange: rapid detection and association with atherosclerosis
Q42505831HMG-CoA reductase inhibitor stabilizes rabbit atheroma by increasing basal NO and decreasing superoxide
Q34119124High density lipoprotein is targeted for oxidation by myeloperoxidase in rheumatoid arthritis
Q33817228High density lipoprotein oxidation: in vitro susceptibility and potential in vivo consequences
Q36002630High-density lipoprotein protects macrophages from oxidized low-density lipoprotein-induced apoptosis by promoting efflux of 7-ketocholesterol via ABCG1
Q38220761High-density lipoproteins as modulators of endothelial cell functions: alterations in patients with coronary artery disease
Q34455031Homocysteine and cardiovascular disease in diabetes mellitus
Q28479210Human apolipoprotein A-I-derived amyloid: its association with atherosclerosis
Q45005902Human atherosclerotic intima and blood of patients with established coronary artery disease contain high density lipoprotein damaged by reactive nitrogen species
Q47975180Human low density lipoprotein as a target of hypochlorite generated by myeloperoxidase
Q37359571Human neutrophils employ chlorine gas as an oxidant during phagocytosis
Q37363040Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to convert hydroxy-amino acids into glycolaldehyde, 2-hydroxypropanal, and acrolein. A mechanism for the generation of highly reactive alpha-hydroxy and alpha,beta-unsatu
Q34066009Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to oxidize alpha-amino acids to a family of reactive aldehydes. Mechanistic studies identifying labile intermediates along the reaction pathway
Q43650867Human neutrophils employ the myeloperoxidase/hydrogen peroxide/chloride system to oxidatively damage apolipoprotein A-I.
Q44008156Human neutrophils oxidize low-density lipoprotein by a hypochlorous acid-dependent mechanism: the role of vitamin C.
Q35764845Human suction blister interstitial fluid prevents metal ion-dependent oxidation of low density lipoprotein by macrophages and in cell-free systems
Q33825419Humans with atherosclerosis have impaired ABCA1 cholesterol efflux and enhanced high-density lipoprotein oxidation by myeloperoxidase
Q43647810Hypochlorite induces the formation of LDL(-), a potentially atherogenic low density lipoprotein subspecies
Q40945169Hypochlorite modification of high density lipoprotein: effects on cholesterol efflux from J774 macrophages
Q44643196Hypochlorite-Mediated Fragmentation of Hyaluronan, Chondroitin Sulfates, and RelatedN-Acetyl Glycosamines: Evidence for Chloramide Intermediates, Free Radical Transfer Reactions, and Site-Specific Fragmentation
Q41952132Hypochlorite-induced damage to proteins: formation of nitrogen-centred radicals from lysine residues and their role in protein fragmentation
Q53854794Hypochlorite-induced damage to red blood cells: evidence for the formation of nitrogen-centred radicals.
Q42993746Hypochlorite-induced oxidation of proteins in plasma: formation of chloramines and nitrogen-centred radicals and their role in protein fragmentation
Q44031789Hypochlorite-modified high density lipoprotein, a high affinity ligand to scavenger receptor class B, type I, impairs high density lipoprotein-dependent selective lipid uptake and reverse cholesterol transport
Q40795530Hypochlorite-modified high-density lipoprotein acts as a sink for myeloperoxidase in vitro
Q39585678Hypochlorite-modified high-density lipoprotein promotes induction of HO-1 in endothelial cells via activation of p42/44 MAPK and zinc finger transcription factor Egr-1.
Q43559341Hypochlorite-modified low density lipoprotein inhibits nitric oxide synthesis in endothelial cells via an intracellular dislocalization of endothelial nitric-oxide synthase
Q74445963Hypochlorite-modified low-density lipoprotein stimulates human polymorphonuclear leukocytes for enhanced production of reactive oxygen metabolites, enzyme secretion, and adhesion to endothelial cells
Q41289645Hypochlorous acid and its pharmacological antagonism: an update picture
Q37446863Hypochlorous acid converts the gamma-glutamyl group of glutathione disulfide to 5-hydroxybutyrolactam, a potential marker for neutrophil activation
Q44448828Hypochlorous acid generated by myeloperoxidase modifies adjacent tryptophan and glycine residues in the catalytic domain of matrix metalloproteinase-7 (matrilysin): an oxidative mechanism for restraining proteolytic activity during inflammation
Q43726485Hypochlorous acid oxygenates the cysteine switch domain of pro-matrilysin (MMP-7). A mechanism for matrix metalloproteinase activation and atherosclerotic plaque rupture by myeloperoxidase
Q28478114Hypochlorous acid-induced heme degradation from lactoperoxidase as a novel mechanism of free iron release and tissue injury in inflammatory diseases
Q37406247Hypochlorous acid-induced heme oxygenase-1 gene expression promotes human endothelial cell survival
Q43897071Hypochlorous acid-modified low-density lipoprotein inactivates the lysosomal protease cathepsin B: protection by ascorbic and lipoic acids
Q34528130Identification in human atherosclerotic lesions of GA-pyridine, a novel structure derived from glycolaldehyde-modified proteins
Q37340646Identification of lysophosphatidylcholine-chlorohydrin in human atherosclerotic lesions.
Q48615832Immunohistochemical and genetic evidence of myeloperoxidase involvement in multiple sclerosis
Q77505427Immunohistochemical detection of hypochlorite-modified proteins in glomeruli of human membranous glomerulonephritis
Q35747219Immunohistochemical detection of myeloperoxidase and its oxidation products in Kupffer cells of human liver
Q43640428Immunohistochemical distribution and quantitative biochemical detection of advanced glycation end products in fetal to adult rats and in rats with streptozotocin-induced diabetes
Q35764605Immunological evidence for hypochlorite-modified proteins in human kidney
Q35166941Impact of HDL oxidation by the myeloperoxidase system on sterol efflux by the ABCA1 pathway
Q37665476Impact of myeloperoxidase-LDL interactions on enzyme activity and subsequent posttranslational oxidative modifications of apoB-100.
Q28350068Increased atherosclerosis in myeloperoxidase-deficient mice
Q38083555Inflammation and immune system interactions in atherosclerosis
Q35739814Inflammatory and oxidative markers in atherosclerosis: relationship to outcome
Q43202739Inflammatory proteins on HDL: what are we measuring?
Q28395876Inhaled matters of the heart
Q34155186Inhibition of hypochlorous acid-induced cellular toxicity by nitrite
Q44395889Inhibition of hypochlorous acid-induced oxidative reactions by nitrite: is nitrite an antioxidant?
Q40865183Inhibition of inducible nitric oxide synthesis by oxidized lipoprotein(a) in a murine macrophage cell line.
Q34478086Interactions of nitric oxide-derived reactive nitrogen species with peroxidases and lipoxygenases.
Q90378589Iodide modulates protein damage induced by the inflammation-associated heme enzyme myeloperoxidase
Q57185465Isolevuglandins and Cardiovascular Disease
Q59400065Kinetics and Thermodynamics of Halide and Nitrite Oxidation by Mammalian Heme Peroxidases
Q73923990Kinetics of tryptophan oxidation in plasma lipoproteins by myeloperoxidase-generated HOCl
Q34249723Linoleic acid hydroperoxide reacts with hypochlorous acid, generating peroxyl radical intermediates and singlet molecular oxygen
Q42615245Lipid oxidation by hypochlorous acid: chlorinated lipids in atherosclerosis and myocardial ischemia
Q37951442Lipid rafts and redox regulation of cellular signaling in cholesterol induced atherosclerosis
Q36228526Lipoprotein oxidation in cardiovascular disease: chief culprit or innocent bystander?
Q37707415Lipoprotein-associated phospholipase A2: role in atherosclerosis and utility as a cardiovascular biomarker
Q37337498Lipoproteomics: using mass spectrometry-based proteomics to explore the assembly, structure, and function of lipoproteins
Q35751034Lipoxygenase contributes to the oxidation of lipids in human atherosclerotic plaques
Q43943413Low density lipoprotein of synovial fluid in inflammatory joint disease is mildly oxidized.
Q41615081Low-density lipoprotein and oxidised low-density lipoprotein: their role in the development of atherosclerosis
Q37091275Low-density lipoprotein modified by myeloperoxidase in inflammatory pathways and clinical studies.
Q38619292Low-density lipoprotein modified by myeloperoxidase oxidants induces endothelial dysfunction
Q54201614Lyme Disease-Associated IgG4 Autoantibodies Correlate with Synovial Pathology in Antibiotic-Refractory Lyme Arthritis.
Q33195740Lysine residues direct the chlorination of tyrosines in YXXK motifs of apolipoprotein A-I when hypochlorous acid oxidizes high density lipoprotein
Q28359694Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes
Q22253929Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species
Q37936512Mechanisms and consequences of oxidative damage to extracellular matrix.
Q37785293Mechanisms of LDL oxidation
Q33603019Mechanisms of oxidative damage by myeloperoxidase in atherosclerosis and other inflammatory disorders
Q38060209Metabolomics and ischaemic heart disease.
Q36858466Methionine oxidation impairs reverse cholesterol transport by apolipoprotein A-I.
Q52688145Methionine oxidized apolipoprotein A-I at the crossroads of HDL biogenesis and amyloid formation.
Q98726639MicroRNA sequences modulating inflammation and lipid accumulation in macrophage "foam" cells: Implications for atherosclerosis
Q46888536Mitochondria-targeted colorimetric and fluorescent probes for hypochlorite and their applications for in vivo imaging
Q77907835Modification of proteins and lipids by myeloperoxidase
Q33897803Modifying apolipoprotein A-I by malondialdehyde, but not by an array of other reactive carbonyls, blocks cholesterol efflux by the ABCA1 pathway
Q92383461Molecular Magnetic Resonance Imaging Using a Redox-Active Iron Complex
Q33473042Monocytes and neutrophils expressing myeloperoxidase occur in fibrous caps and thrombi in unstable coronary plaques
Q50912369Myeloperoxidase Levels and Its Product 3-Chlorotyrosine Predict Chronic Kidney Disease Severity and Associated Coronary Artery Disease.
Q46808193Myeloperoxidase activity imaging using (67)Ga labeled substrate
Q37393355Myeloperoxidase acts as a source of free iron during steady-state catalysis by a feedback inhibitory pathway
Q36014190Myeloperoxidase aids prognostication together with N-terminal pro-B-type natriuretic peptide in high-risk patients with acute ST elevation myocardial infarction
Q41879141Myeloperoxidase and elastase are only expressed by neutrophils in normal and in inflamed liver
Q46900591Myeloperoxidase and inflammatory proteins: pathways for generating dysfunctional high-density lipoprotein in humans
Q73378050Myeloperoxidase binds to low-density lipoprotein: potential implications for atherosclerosis
Q41880909Myeloperoxidase deficiency preserves vasomotor function in humans
Q52629638Myeloperoxidase derived oxidants damage artery wall proteins in an animal model of chronic kidney disease accelerated atherosclerosis.
Q36302434Myeloperoxidase evokes substantial vasomotor responses in isolated skeletal muscle arterioles of the rat.
Q54764581Myeloperoxidase gene variation as a determinant of atherosclerosis progression in the abdominal and thoracic aorta: an autopsy study.
Q46834806Myeloperoxidase generates 5-chlorouracil in human atherosclerotic tissue: a potential pathway for somatic mutagenesis by macrophages
Q46960352Myeloperoxidase impairs ABCA1-dependent cholesterol efflux through methionine oxidation and site-specific tyrosine chlorination of apolipoprotein A-I.
Q64077636Myeloperoxidase inhibition in mice alters atherosclerotic lesion composition
Q57414500Myeloperoxidase is associated with incident coronary heart disease independently of traditional risk factors: results from the MONICA/KORA Augsburg study
Q35564735Myeloperoxidase is increased in human cerebral aneurysms and increases formation and rupture of cerebral aneurysms in mice
Q22254048Myeloperoxidase is involved in H2O2-induced apoptosis of HL-60 human leukemia cells
Q41896945Myeloperoxidase is not useful for detecting stress inducible myocardial ischemia but may be indicative of the severity of coronary artery disease
Q34072878Myeloperoxidase levels predicts angiographic severity of coronary artery disease in patients with chronic stable angina
Q35541075Myeloperoxidase modulation by LDL apheresis in familial hypercholesterolemia
Q44485540Myeloperoxidase polymorphisms in brain infarction. Association with infarct size and functional outcome
Q34791672Myeloperoxidase produces nitrating oxidants in vivo
Q37992526Myeloperoxidase production by macrophage and risk of atherosclerosis
Q35838851Myeloperoxidase targets apolipoprotein A-I, the major high density lipoprotein protein, for site-specific oxidation in human atherosclerotic lesions
Q34291776Myeloperoxidase, inflammation, and dysfunctional high-density lipoprotein
Q37353408Myeloperoxidase, modified lipoproteins, and atherogenesis
Q42842899Myeloperoxidase-dependent LDL modifications in bloodstream are mainly predicted by angiotensin II, adiponectin, and myeloperoxidase activity: a cross-sectional study in men
Q42502848Myeloperoxidase-dependent generation of hypochlorite-modified proteins in human placental tissues during normal pregnancy
Q37078673Myeloperoxidase-derived oxidants inhibit sarco/endoplasmic reticulum Ca2+-ATPase activity and perturb Ca2+ homeostasis in human coronary artery endothelial cells
Q39255171Myeloperoxidase-derived oxidants modify apolipoprotein A-I and generate dysfunctional high-density lipoproteins: comparison of hypothiocyanous acid (HOSCN) with hypochlorous acid (HOCl).
Q34162955Myeloperoxidase-derived oxidation: mechanisms of biological damage and its prevention
Q34006268Myeloperoxidase-generated oxidants and atherosclerosis
Q33852491Myeloperoxidase-generated reactive nitrogen species convert LDL into an atherogenic form in vitro
Q28200597Myeloperoxidase-mediated LDL oxidation and endothelial cell toxicity of oxidized LDL: attenuation by (-)-epicatechin
Q35536293Myeloperoxidase-mediated Methionine Oxidation Promotes an Amyloidogenic Outcome for Apolipoprotein A-I.
Q51204343Myeloperoxidase-mediated protein lysine oxidation generates 2-aminoadipic acid and lysine nitrile in vivo.
Q36860606Myeloperoxidase: a target for new drug development?
Q34545509Myeloperoxidase: a therapeutic target for preventing insulin resistance and the metabolic sequelae of obesity?
Q33729198Myeloperoxidase: an oxidative pathway for generating dysfunctional high-density lipoprotein
Q42255196Myocardial oxidative stress, osteogenic phenotype, and energy metabolism are differentially involved in the initiation and early progression of delta-sarcoglycan-null cardiomyopathy
Q36296514N-Acetylcysteine attenuates tumor necrosis factor alpha levels in autoimmune inner ear disease patients
Q100568733NET-associated citrullinated histones promote LDL aggregation and foam cell formation in vitro
Q41996261Native high density lipoproteins (HDL) interfere with platelet activation induced by oxidized low density lipoproteins (OxLDL)
Q36624064Native low density lipoprotein promotes lipid raft formation in macrophages
Q34339353Nature-inspired nanoformulations for contrast-enhanced in vivo MR imaging of macrophages
Q38648056Neutrophil proteolytic activation cascades: a possible mechanistic link between chronic periodontitis and coronary heart disease
Q38628708Neutrophil's weapons in atherosclerosis
Q42700363Neutrophils, Hypercholesterolemia, and Atherogenesis
Q36088357New biomarkers for primary mitral regurgitation
Q35106766New insights into the effects of the protein moiety of oxidized LDL (oxLDL)
Q28645799Nitric oxide is a physiological substrate for mammalian peroxidases
Q84320607Nitrite, a reactive nitrogen species, protects human alpha-2-macroglobulin from halogenated oxidant, HOCl
Q78099814Nitrogen dioxide radical generated by the myeloperoxidase-hydrogen peroxide-nitrite system promotes lipid peroxidation of low density lipoprotein
Q53090374Oral administration of alkaloid fraction from Ruta graveolens inhibits oxidative stress and inflammation in hypercholesterolemic rabbits.
Q58581080Overriding Phthalate Decomposition When Exploring Mycophenolic Acid Intermediates as Selenium-Based ROS Biological Probes
Q77718601Oxidants and antioxidants in the pathogenesis of atherosclerosis: implications for the oxidized low density lipoprotein hypothesis
Q38209427Oxidation and modification of extracellular matrix and its role in disease
Q33902023Oxidation of apolipoprotein A-I by myeloperoxidase impairs the initial interactions with ABCA1 required for signaling and cholesterol export
Q73110368Oxidation of heparin-treated low density lipoprotein by peroxidases
Q33963758Oxidation of low-density lipoprotein by hemoglobin-hemichrome.
Q46269480Oxidative Stress in Human Atherothrombosis: Sources, Markers and Therapeutic Targets.
Q45114412Oxidative modification of low-density lipoprotein: lipid peroxidation by myeloperoxidase in the presence of nitrite
Q73370736Oxidative modifications of apoB-100 by exposure of low density lipoproteins to HOCL in vitro
Q33554184Oxidative risk for atherothrombotic cardiovascular disease
Q37501271Oxidative stress and cardiovascular disease: novel tools give (free) radical insight
Q33822180Oxidative stress and cellular immunity in patients with recurrent aphthous ulcers
Q36905196Oxidative stress and endothelial dysfunction in vascular disease
Q35088524Oxidative stress: new approaches to diagnosis and prognosis in atherosclerosis
Q73407786Oxidative tyrosylation of high density lipoprotein impairs biliary sterol secretion in rats
Q34658022Oxidized amino acids: culprits in human atherosclerosis and indicators of oxidative stress
Q77910747Oxysterols and atherosclerosis
Q40343992Paradoxical actions of antioxidants in the oxidation of low density lipoprotein by peroxidases
Q43089504Passive immunization with hypochlorite-oxLDL specific antibodies reduces plaque volume in LDL receptor-deficient mice
Q33610044Pathophysiology of nitric oxide and related species: free radical reactions and modification of biomolecules
Q60998579Pathways of phospholipid oxidation by HOCl in human LDL detected by LC-MS
Q44249438Patterns of oxidized epitopes, but not NF-kappa B expression, change during atherogenesis in WHHL rabbits
Q39034108Pentoxifylline Inhibits Epidural Fibrosis in Post-Laminectomy Rats.
Q44688340Peroxisome proliferator-activated receptor gamma ligands regulate myeloperoxidase expression in macrophages by an estrogen-dependent mechanism involving the -463GA promoter polymorphism
Q34191993Phagocytes produce 5-chlorouracil and 5-bromouracil, two mutagenic products of myeloperoxidase, in human inflammatory tissue
Q44394291Phospholipid chlorohydrins cause ATP depletion and toxicity in human myeloid cells
Q57947449Plasma oxidized high-density lipoprotein and glycated apolipoprotein A-I concentrations in ST-segment elevation myocardial infarction patients with stress hyperglycaemia or high thrombus burden
Q44159839Polymorphic metabolizing genes and susceptibility to atherosclerosis among cigarette smokers
Q38095369Polymorphonuclear neutrophils and instability of the atherosclerotic plaque: a causative role?
Q51032319Positive association between plasma levels of oxidized low-density lipoprotein and myeloperoxidase after hemodialysis in patients with diabetic end-stage renal disease.
Q37770003Potential for chlorine gas-induced injury in the extrapulmonary vasculature.
Q36176582Potential role of plasma myeloperoxidase level in predicting long-term outcome of acute myocardial infarction
Q36484657Potential to inhibit growth of atherosclerotic plaque development through modulation of macrophage neopterin/7,8-dihydroneopterin synthesis
Q37353371Presence of hypochlorite-modified proteins in human atherosclerotic lesions
Q45275694Probucol protects against hypochlorite-induced endothelial dysfunction: identification of a novel pathway of probucol oxidation to a biologically active intermediate.
Q31628322Production of brominating intermediates by myeloperoxidase. A transhalogenation pathway for generating mutagenic nucleobases during inflammation
Q40281726Proliferation of macrophages due to the inhibition of inducible nitric oxide synthesis by oxidized low-density lipoproteins.
Q74484834Protective effect of fluvastatin sodium (XU-62-320), a 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, on oxidative modification of human low-density lipoprotein in vitro
Q26827410Protein carbamylation and cardiovascular disease
Q53226236Protein-bound acrolein: a novel marker of oxidative stress in Alzheimer's disease.
Q36058528Protein-bound acrolein: potential markers for oxidative stress
Q35581112Race-specific associations of myeloperoxidase with atherosclerosis in a population-based sample: the Dallas Heart Study
Q89503367Randomized clinical trial of the effect of intraoperative humidified carbon dioxide insufflation in open laparotomy for colorectal resection
Q30372838Rational drug design applied to myeloperoxidase inhibition.
Q36118999Reactive Oxygen Species Donors Increase the Responsiveness of Dorsal Horn Neurons and Induce Mechanical Hyperalgesia in Rats
Q35165194Reactive oxygen species in cardiovascular disease.
Q37361893Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability
Q42995934Reagent or myeloperoxidase-generated hypochlorite affects discrete regions in lipid-free and lipid-associated human apolipoprotein A-I.
Q45338276Redox Regulation of Inflammatory Processes Is Enzymatically Controlled.
Q35576288Redox properties of myeloperoxidase
Q46305715Regulation and function of endothelial glycocalyx layer in vascular diseases
Q54587897Relation of myeloperoxidase promoter polymorphism and long-term hormone replacement therapy to oxidized low-density lipoprotein autoantibodies in postmenopausal women.
Q42089083Relationship of serum inflammatory biomarkers with plaque inflammation assessed by FDG PET/CT: the dal-PLAQUE study.
Q37838428Reno-cerebrovascular disease: linking the nephron and neuron
Q42807176Rhodamine-modified upconversion nanophosphors for ratiometric detection of hypochlorous acid in aqueous solution and living cells.
Q36229648Role of Myeloperoxidase Oxidants in the Modulation of Cellular Lysosomal Enzyme Function: A Contributing Factor to Macrophage Dysfunction in Atherosclerosis?
Q37798811Role of Myeloperoxidase in Cardiology
Q24683780Role of oxidants in microbial pathophysiology
Q37045445Role of oxidative stress and nitric oxide in atherothrombosis
Q34006248Role of reactive aldehyde in cardiovascular diseases
Q42931100S100A12 links to thoracic aortic aneurysms
Q61978281Salicylate promotes myeloperoxidase-initiated LDL oxidation: antagonization by its metabolite gentisic acid
Q45078277Screening and identifying the myocardial-injury protective ingredients from Sheng-Mai-San
Q41937076Secondary radicals derived from chloramines of apolipoprotein B-100 contribute to HOCl-induced lipid peroxidation of low-density lipoproteins
Q27690671Sequence conservation of apolipoprotein A-I affords novel insights into HDL structure-function
Q45800383Serum malondialdehyde levels, myeloperoxidase and catalase activities in patients with nephrotic syndrome.
Q42737190Serum myeloperoxidase: a novel biomarker for evaluation of patients with acute coronary syndrome
Q89881813Site-specific 5-hydroxy-tryptophan incorporation into apolipoprotein A-I impairs cholesterol efflux activity and high density lipoprotein biogenesis
Q35783321Site-specific oxidation of apolipoprotein A-I impairs cholesterol export by ABCA1, a key cardioprotective function of HDL.
Q58075704Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation
Q44166458Spatial mapping of pulmonary and vascular nitrotyrosine reveals the pivotal role of myeloperoxidase as a catalyst for tyrosine nitration in inflammatory diseases
Q37173205The HDL proteome: a marker--and perhaps mediator--of coronary artery disease
Q90449141The Peroxisome Proliferator-Activated Receptor γ Agonist Pioglitazone Protects Vascular Endothelial Function in Hypercholesterolemic Rats by Inhibiting Myeloperoxidase
Q63978868The Resurrection of Myeloperoxidase as a Therapeutic Target: Is it Lazarus or Just an Apparition?
Q49603161The chlorinated lipidome originating from myeloperoxidase-derived HOCl targeting plasmalogens: Metabolism, clearance, and biological properties
Q40271950The critical role of myeloperoxidase in Streptococcus pneumoniae clearance and tissue damage during mouse acute otitis media
Q50496523The effect of certain steroid hormones on the expression of genes involved in the metabolism of free radicals.
Q35697554The human myeloperoxidase gene is regulated by LXR and PPARalpha ligands
Q42137439The hypotensive effect of acute and chronic AMP-activated protein kinase activation in normal and hyperlipidemic mice
Q34986351The macrophage foam cell as a target for therapeutic intervention
Q34347558The modern pharmacology of paracetamol: therapeutic actions, mechanism of action, metabolism, toxicity and recent pharmacological findings
Q24656816The molecular mechanisms of the thrombotic complications of atherosclerosis
Q37512515The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport
Q33853348The myeloperoxidase system of human phagocytes generates Nepsilon-(carboxymethyl)lysine on proteins: a mechanism for producing advanced glycation end products at sites of inflammation
Q41146808The nitroxide radical TEMPOL prevents obesity, hyperlipidaemia, elevation of inflammatory cytokines, and modulates atherosclerotic plaque composition in apoE-/- mice
Q28396048The principal eosinophil peroxidase product, HOSCN, is a uniquely potent phagocyte oxidant inducer of endothelial cell tissue factor activity: a potential mechanism for thrombosis in eosinophilic inflammatory states
Q39906664The proper study of mankind
Q37205406The reaction of HOCl and cyanocobalamin: corrin destruction and the liberation of cyanogen chloride.
Q24629974The response-to-retention hypothesis of early atherogenesis
Q37631070The role of hypothiocyanous acid (HOSCN) in biological systems.
Q37291868The role of myeloperoxidase (MPO) for prognostic evaluation in sensitive cardiac troponin I negative chest pain patients in the emergency department
Q37049625The role of myeloperoxidase in HDL oxidation and atherogenesis
Q37275296The role of oxidized low-density lipoproteins in atherosclerosis: the myths and the facts.
Q34319485The role of vitamin E in atherogenesis: linking the chemical, biological and clinical aspects of the disease
Q35157613The role of vitamin E in atherosclerosis
Q38065232The roles of garlic on the lipid parameters: a systematic review of the literature
Q30240734The roles of myeloperoxidase in coronary artery disease and its potential implication in plaque rupture.
Q40617645The state of macrophage differentiation determines the TNFα response to nitrated lipoprotein uptake
Q36052967The use of myeloperoxidase as a risk marker for atherosclerosis
Q36182725Thematic review series: The immune system and atherogenesis. Cytokine regulation of macrophage functions in atherogenesis
Q53394627Titanium dioxide as a catalyst support in heterogeneous catalysis.
Q46071984Transgenic mice express human MPO -463G/A alleles at atherosclerotic lesions, developing hyperlipidemia and obesity in -463G males
Q36386406Tripping up Trp: Modification of protein tryptophan residues by reactive oxygen species, modes of detection, and biological consequences
Q46842392Upregulation of endothelial and inducible nitric oxide synthase expression by reactive oxygen species
Q73853371Urate attenuates oxidation of native low-density lipoprotein by hypochlorite and the subsequent lipoprotein-induced respiratory burst activities of polymorphonuclear leukocytes
Q24559986Uric acid: A new look at an old risk marker for cardiovascular disease, metabolic syndrome, and type 2 diabetes mellitus: The urate redox shuttle
Q37142318Using tandem mass spectrometry to quantify site-specific chlorination and nitration of proteins: model system studies with high-density lipoprotein oxidized by myeloperoxidase.
Q37392502VPO1 mediates oxidation of LDL and formation of foam cells
Q60047032Vascular Oxidative Stress: Impact and Therapeutic Approaches
Q41998801Vitamin C protects against and reverses specific hypochlorous acid- and chloramine-dependent modifications of low-density lipoprotein
Q41769762When and why a water-soluble antioxidant becomes pro-oxidant during copper-induced low-density lipoprotein oxidation: a study using uric acid
Q74465119pH Heterogeneity of human and rabbit atherosclerotic plaques; a new insight into detection of vulnerable plaque

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