Tankyrase1-mediated poly(ADP-ribosyl)ation of TRF1 maintains cell survival after telomeric DNA damage

scientific article

Tankyrase1-mediated poly(ADP-ribosyl)ation of TRF1 maintains cell survival after telomeric DNA damage is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/NAR/GKX083
P932PMC publication ID5397190
P698PubMed publication ID28160604

P2093author name stringArthur S Levine
Li Lan
Satoshi Nakajima
Hao Chen
Lu Yang
Ying Gao
Luxi Sun
Yaqun Teng
P2860cites workTankyrase, a poly(ADP-ribose) polymerase at human telomeresQ22008022
Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeresQ22254585
Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeresQ24291989
Structural basis and sequence rules for substrate recognition by Tankyrase explain the basis for cherubism diseaseQ24299239
Chromophore-assisted light inactivation (CALI) using the phototoxic fluorescent protein KillerRed.Q50690849
Crystal structure of a tankyrase 1-telomere repeat factor 1 complex.Q50863793
Telomere end-replication problem and cell agingQ56508218
Tankyrase promotes telomere elongation in human cellsQ56969704
RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signallingQ24299327
How the human telomeric proteins TRF1 and TRF2 recognize telomeric DNA: a view from high-resolution crystal structuresQ24323494
Domain specific interaction in the XRCC1-DNA polymerase beta complexQ24518994
Tankyrase-2 oligomerizes with tankyrase-1 and binds to both TRF1 (telomere-repeat-binding factor 1) and IRAP (insulin-responsive aminopeptidase)Q24533586
An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase IIIQ24615666
Oxidative damage in telomeric DNA disrupts recognition by TRF1 and TRF2Q24793970
Structure of the TRFH dimerization domain of the human telomeric proteins TRF1 and TRF2Q27634733
Structural basis for the phototoxicity of the fluorescent protein KillerRedQ27656817
Structural basis of selective inhibition of human tankyrasesQ27676673
Specific Association of Human Telomerase Activity with Immortal Cells and CancerQ27860801
TRF1 is degraded by ubiquitin-mediated proteolysis after release from telomeresQ28119006
Cell cycle dependent localization of the telomeric PARP, tankyrase, to nuclear pore complexes and centrosomesQ28145946
Identification of a tankyrase-binding motif shared by IRAP, TAB182, and human TRF1 but not mouse TRF1. NuMA contains this RXXPDG motif and is a novel tankyrase partnerQ28206417
Shelterin: the protein complex that shapes and safeguards human telomeresQ28272546
Loss of Rap1 induces telomere recombination in the absence of NHEJ or a DNA damage signalQ28506435
Oxidative stress induces persistent telomeric DNA damage responsible for nuclear morphology change in mammalian cellsQ28544458
A highly selective telomerase inhibitor limiting human cancer cell proliferationQ29301431
Single-strand break repair and genetic diseaseQ29615347
Telomeres and human disease: ageing, cancer and beyondQ29615353
How shelterin protects mammalian telomeresQ29615744
Regulation of telomerase by telomeric proteinsQ29616133
In situ analysis of repair processes for oxidative DNA damage in mammalian cells.Q31111805
Telomeres: protecting chromosomes against genome instabilityQ33740892
Alternative lengthening of telomeres: models, mechanisms and implicationsQ34107386
Spatial and temporal cellular responses to single-strand breaks in human cells.Q34197035
Removal of shelterin reveals the telomere end-protection problemQ34272638
The PARP superfamilyQ34335821
PARP1 Is a TRF2-associated poly(ADP-ribose)polymerase and protects eroded telomeresQ34483600
TRF1 negotiates TTAGGG repeat-associated replication problems by recruiting the BLM helicase and the TPP1/POT1 repressor of ATR signalingQ34518947
Poly-ADP ribosylation of PTEN by tankyrases promotes PTEN degradation and tumor growthQ34981637
Novel method for site-specific induction of oxidative DNA damage reveals differences in recruitment of repair proteins to heterochromatin and euchromatinQ35057331
DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repairQ35097944
BRCA1 and CtIP promote alternative non-homologous end-joining at uncapped telomeresQ35116646
XRCC1 and DNA strand break repairQ35216366
T-loops and the origin of telomeresQ35741027
Stringent sequence requirements for the formation of human telomeresQ35751600
Targeted DNA damage at individual telomeres disrupts their integrity and triggers cell deathQ35885959
Tankyrases Promote Homologous Recombination and Check Point Activation in Response to DSBsQ35914314
A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damageQ36119231
Poly(ADP-ribosylation) and genomic stabilityQ36164734
Impact of telomerase ablation on organismal viability, aging, and tumorigenesis in mice lacking the DNA repair proteins PARP-1, Ku86, or DNA-PKcsQ36322778
Fluorescent proteins: maturation, photochemistry and photophysicsQ36634546
TRF2-RAP1 is required to protect telomeres from engaging in homologous recombination-mediated deletions and fusionsQ36670262
Rapid regulation of telomere length is mediated by poly(ADP-ribose) polymerase-1.Q36959668
DNA secondary structures: stability and function of G-quadruplex structuresQ37051064
DNA damage response at functional and dysfunctional telomeresQ37058277
Single-strand interruptions in replicating chromosomes cause double-strand breaksQ37093293
Telomere dysfunction and tumour suppression: the senescence connectionQ37171810
Damage response of XRCC1 at sites of DNA single strand breaks is regulated by phosphorylation and ubiquitylation after degradation of poly(ADP-ribose).Q37201500
Tankyrase polymerization is controlled by its sterile alpha motif and poly(ADP-ribose) polymerase domainsQ37598811
Alternative Lengthening of Telomeres is characterized by reduced compaction of telomeric chromatinQ37701313
Tankyrase-targeted therapeutics: expanding opportunities in the PARP familyQ38063790
TRF1 binds a bipartite telomeric site with extreme spatial flexibilityQ38319408
Interchromosomal homology searches drive directional ALT telomere movement and synapsis.Q38953062
Telomerase inhibition enhances the response to anticancer drug treatment in human breast cancer cellsQ40246796
A genetically encoded photosensitizerQ40337535
Preferential accumulation of single-stranded regions in telomeres of human fibroblastsQ41057265
Structural insights into SAM domain-mediated tankyrase oligomerization.Q41954009
The spin trapping of superoxide and hydroxyl free radicals with DMPO (5,5-dimethylpyrroline-N-oxide): more about ironQ43144037
Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stabilityQ48564987
P275copyright licenseCreative Commons Attribution-NonCommercial 4.0 InternationalQ34179348
P6216copyright statuscopyrightedQ50423863
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectDNA damageQ5205747
P304page(s)3906-3921
P577publication date2017-02-04
P1433published inNucleic Acids ResearchQ135122
P1476titleTankyrase1-mediated poly(ADP-ribosyl)ation of TRF1 maintains cell survival after telomeric DNA damage
P478volume45

Reverse relations

cites work (P2860)
Q64104519Emerging roles of eraser enzymes in the dynamic control of protein ADP-ribosylation
Q92572592Loci for human leukocyte telomere length in the Singaporean Chinese population and trans-ethnic genetic studies
Q89581155Nuclear PARPs and genome integrity
Q92495595Stilbene Compounds Inhibit Tumor Growth by the Induction of Cellular Senescence and the Inhibition of Telomerase Activity

Search more.