Human COX20 cooperates with SCO1 and SCO2 to mature COX2 and promote the assembly of cytochrome c oxidase

scientific article

Human COX20 cooperates with SCO1 and SCO2 to mature COX2 and promote the assembly of cytochrome c oxidase is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/HMG/DDU003
P932PMC publication ID4014192
P698PubMed publication ID24403053
P5875ResearchGate publication ID259630929

P2093author name stringScot C Leary
Antoni Barrientos
Aren Boulet
Myriam Bourens
P2860cites workProtein measurement with the Folin phenol reagentQ20900776
SURF1, encoding a factor involved in the biogenesis of cytochrome c oxidase, is mutated in Leigh syndromeQ22008476
Fatal infantile cardioencephalomyopathy with COX deficiency and mutations in SCO2, a COX assembly geneQ22010737
Cytochrome c oxidase subassemblies in fibroblast cultures from patients carrying mutations in COX10, SCO1, or SURF1Q24299371
Cloning of a human gene involved in cytochrome oxidase assembly by functional complementation of an oxa1- mutation in Saccharomyces cerevisiaeQ24310678
Mutations of the SCO1 gene in mitochondrial cytochrome c oxidase deficiency with neonatal-onset hepatic failure and encephalopathy.Q24534480
Tissue-specific cytochrome c oxidase assembly defects due to mutations in SCO2 and SURF1Q24534961
Targeting DNA double-strand breaks with TAL effector nucleasesQ24605087
Structure at 2.7 A resolution of the Paracoccus denitrificans two-subunit cytochrome c oxidase complexed with an antibody FV fragmentQ24657440
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
The whole structure of the 13-subunit oxidized cytochrome c oxidase at 2.8 AQ27732721
Redox-coupled crystal structural changes in bovine heart cytochrome c oxidaseQ27758647
A mitochondrial protease with two catalytic subunits of nonoverlapping specificities.Q27930944
Yeast Oxa1 interacts with mitochondrial ribosomes: the importance of the C-terminal region of Oxa1.Q27931721
Identification of Cox20p, a novel protein involved in the maturation and assembly of cytochrome oxidase subunit 2.Q27932189
Ribosome binding to the Oxa1 complex facilitates co-translational protein insertion in mitochondriaQ27932930
Cox18p is required for export of the mitochondrially encoded Saccharomyces cerevisiae Cox2p C-tail and interacts with Pnt1p and Mss2p in the inner membrane.Q27935218
Mitochondrial protein synthesis is required for maintenance of intact mitochondrial genomes in Saccharomyces cerevisiaeQ27935904
Membrane translocation of mitochondrially coded Cox2p: distinct requirements for export of N and C termini and dependence on the conserved protein Oxa1pQ27935924
Oxa1p mediates the export of the N- and C-termini of pCoxII from the mitochondrial matrix to the intermembrane spaceQ27935994
Oxa1p, an essential component of the N-tail protein export machinery in mitochondriaQ27939168
COX16 encodes a novel protein required for the assembly of cytochrome oxidase in Saccharomyces cerevisiaeQ27939371
Cytochrome c oxidase deficiencyQ28189586
Human SCO1 and SCO2 have independent, cooperative functions in copper delivery to cytochrome c oxidaseQ28269687
Assembly of cytochrome-c oxidase in cultured human cellsQ28276105
The human cytochrome c oxidase assembly factors SCO1 and SCO2 have regulatory roles in the maintenance of cellular copper homeostasisQ28280598
A TALE nuclease architecture for efficient genome editingQ28301656
Chemiosmotic hypothesis of oxidative phosphorylationQ28611218
Formation of the redox cofactor centers during Cox1 maturation in yeast cytochrome oxidase.Q33627236
The bicoid stability factor controls polyadenylation and expression of specific mitochondrial mRNAs in Drosophila melanogasterQ34055376
Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotesQ34175308
Biogenesis and assembly of eukaryotic cytochrome c oxidase catalytic coreQ34220248
Genetic defects of cytochrome c oxidase assembly.Q34317653
Assembly of mitochondrial cytochrome c-oxidase, a complicated and highly regulated cellular processQ34535761
Defects in cytochrome oxidase assembly in humans: lessons from yeastQ34600372
Human SCO2 is required for the synthesis of CO II and as a thiol-disulphide oxidoreductase for SCO1.Q34972244
Multiple roles of the Cox20 chaperone in assembly of Saccharomyces cerevisiae cytochrome c oxidaseQ35748230
Biogenesis of cytochrome oxidase-sophisticated assembly lines in the mitochondrial inner membraneQ36132872
Copper trafficking to the mitochondrion and assembly of copper metalloenzymesQ36456731
Modular assembly of yeast cytochrome oxidaseQ36608388
The endless tale of non-homologous end-joiningQ37048174
PET genes of Saccharomyces cerevisiaeQ37056313
Redox and reactive oxygen species regulation of mitochondrial cytochrome C oxidase biogenesisQ37366433
Structural features of cytochrome oxidaseQ37904162
Shy1p is necessary for full expression of mitochondrial COX1 in the yeast model of Leigh's syndromeQ39646401
Analysis of aminoacylation of human mitochondrial tRNAsQ41244333
Evaluation of the mitochondrial respiratory chain and oxidative phosphorylation system using polarography and spectrophotometric enzyme assaysQ41861486
Recessive dystonia-ataxia syndrome in a Turkish family caused by a COX20 (FAM36A) mutationQ44108174
Mutation in TACO1, encoding a translational activator of COX I, results in cytochrome c oxidase deficiency and late-onset Leigh syndrome.Q45979469
A mutation in the FAM36A gene, the human ortholog of COX20, impairs cytochrome c oxidase assembly and is associated with ataxia and muscle hypotonia.Q47074411
Characterization of SURF-1 expression and Surf-1p function in normal and disease conditions.Q50515893
Oxidative phosphorylation: synthesis of mitochondrially encoded proteins and assembly of individual structural subunits into functional holoenzyme complexesQ57041666
Nuclear functions required for cytochrome c oxidase biogenesis in Saccharomyces cerevisiae. Characterization of mutants in 34 complementation groupsQ70146252
SCO1 and SCO2 act as high copy suppressors of a mitochondrial copper recruitment defect in Saccharomyces cerevisiaeQ71246164
Biochemical, genetic and immunoblot analyses of 17 patients with an isolated cytochrome c oxidase deficiencyQ73089677
In vivo labeling and analysis of mitochondrial translation products in budding and in fission yeastsQ82882608
P433issue11
P921main subjectmitochondrial cytochrome c oxidase assemblyQ21100869
cytochrome c oxidase assembly factor COX20Q21109894
P304page(s)2901-2913
P577publication date2014-01-08
P1433published inHuman Molecular GeneticsQ2720965
P1476titleHuman COX20 cooperates with SCO1 and SCO2 to mature COX2 and promote the assembly of cytochrome c oxidase
P478volume23

Reverse relations

cites work (P2860)
Q38721574A CMC1-knockout reveals translation-independent control of human mitochondrial complex IV biogenesis.
Q35009121A truncating PET100 variant causing fatal infantile lactic acidosis and isolated cytochrome c oxidase deficiency
Q60954715APOPT1/COA8 assists COX assembly and is oppositely regulated by UPS and ROS
Q56760543Assembly of mammalian oxidative phosphorylation complexes I-V and supercomplexes
Q40814307Association between SCO2 mutation and extreme myopia in Japanese patients
Q47709325Building the CuA site of cytochrome c oxidase: a complicated, redox-dependent process driven by a surprisingly large complement of accessory proteins
Q89729173COA6 Facilitates Cytochrome c Oxidase Biogenesis as Thiol-reductase for Copper Metallochaperones in Mitochondria
Q92087519COA6 Is Structurally Tuned to Function as a Thiol-Disulfide Oxidoreductase in Copper Delivery to Mitochondrial Cytochrome c Oxidase
Q24338334COA6 is a mitochondrial complex IV assembly factor critical for biogenesis of mtDNA-encoded COX2
Q47643939COX16 promotes COX2 metallation and assembly during respiratory complex IV biogenesis.
Q93082239Comparative Proteomic Analysis of Proteins Involved in Bioenergetics Pathways Associated with Human Sperm Motility
Q38559272Copper trafficking to the secretory pathway
Q36255720Cytochrome c Oxidase Biogenesis and Metallochaperone Interactions: Steps in the Assembly Pathway of a Bacterial Complex
Q92072023ERα Signaling Increased IL-17A Production in Th17 Cells by Upregulating IL-23R Expression, Mitochondrial Respiration, and Proliferation
Q100395210Expanding the genotype-phenotype correlation of childhood sensory polyneuropathy of genetic origin
Q59808357Human COX7A2L Regulates Complex III Biogenesis and Promotes Supercomplex Organization Remodeling without Affecting Mitochondrial Bioenergetics
Q38711145Human mitochondrial cytochrome c oxidase assembly factor COX18 acts transiently as a membrane insertase within the subunit 2 maturation module
Q47430825In vitro and in vivo studies of the ALS-FTLD protein CHCHD10 reveal novel mitochondrial topology and protein interactions.
Q47783506Mitochondrial cytochrome c oxidase biogenesis: Recent developments.
Q36551271Mitochondrial disease genes COA6, COX6B and SCO2 have overlapping roles in COX2 biogenesis
Q31136316Multiple across-strain and within-strain QTLs suggest highly complex genetic architecture for hypoxia tolerance in channel catfish
Q64041294Novel pathogenic variants causing dysarthria, ataxia, and sensory neuropathy
Q54963717Plant Mitochondrial Inner Membrane Protein Insertion.
Q40933332Stroke-Like Presentation Following Febrile Seizure in a Patient with 1q43q44 Deletion Syndrome.
Q51745738The Complexity of Mitochondrial Complex IV: An Update of Cytochrome c Oxidase Biogenesis in Plants.
Q47296599The mammalian phosphate carrier SLC25A3 is a mitochondrial copper transporter required for cytochrome c oxidase biogenesis.
Q47074405The mitochondrial TMEM177 associates with COX20 during COX2 biogenesis
Q41619805The ribosome-associated Mba1 escorts Cox2 from insertion machinery to maturing assembly intermediates
Q33737679Tissue- and Condition-Specific Isoforms of Mammalian Cytochrome c Oxidase Subunits: From Function to Human Disease
Q39024278Tissue- and species-specific differences in cytochrome c oxidase assembly induced by SURF1 defects.
Q35687142Yeast as a system for modeling mitochondrial disease mechanisms and discovering therapies

Search more.