Increased generation of fibrocytes in thyroid-associated ophthalmopathy

scientific article

Increased generation of fibrocytes in thyroid-associated ophthalmopathy is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1210/JC.2009-1614
P932PMC publication ID2805489
P698PubMed publication ID19897675

P50authorKelvin ChongQ45933657
Terry J. SmithQ45933677
Raymond S DouglasQ51353730
P2093author name stringNikoo F Afifiyan
Andrew G Gianoukakis
Catherine J Hwang
Patrick Richards
Uzma Haider
P2860cites workThymic hyperplasia in patients with Graves' disease. Identification of thyrotropin receptors in human thymusQ24561889
Key apoptotic pathways for heat-induced programmed germ cell death in the testisQ28574219
Circulating peripheral blood fibrocytes in human fibrotic interstitial lung diseaseQ30442380
The role of CXC chemokines in pulmonary fibrosisQ30443091
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Peripheral blood fibrocytes from burn patients: identification and quantification of fibrocytes in adherent cells cultured from peripheral blood mononuclear cellsQ34148399
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Immune function of thyroid stimulating hormone and receptor.Q34581191
Thyrotropin receptor expression in orbital adipose/connective tissues from patients with thyroid-associated ophthalmopathyQ34599712
Orbital fibroblasts exhibit a novel pattern of responses to proinflammatory cytokines: potential basis for the pathogenesis of thyroid-associated ophthalmopathyQ34599722
Novel functions of the CD34 familyQ34873662
TNFalpha mediates the skeletal effects of thyroid-stimulating hormoneQ35036487
Regulation of lipolysis during the neonatal period. Importance of thyrotropinQ35593693
Physiological relevance of thyroid stimulating hormone and thyroid stimulating hormone receptor in tissues other than the thyroidQ35605723
Oxidative stress and Graves' ophthalmopathy: in vitro studies and therapeutic implications.Q35646567
Expression of thyrotropin-receptor mRNA in healthy and Graves' disease retro-orbital tissueQ72226506
Thyroid-stimulating immunoglobulinsQ72541493
TSH-displacing activity versus TSH-binding inhibiting activity of immunoglobulins from patients with Graves' diseaseQ72571300
Analysis of human thyrotropin receptor gene expression and immunoreactivity in human orbital tissueQ73515509
Cytokine-induced lymphocyte chemoattraction from cultured human thyrocytes: evidence for interleukin-16 and regulated upon activation, normal T cell expressed, and secreted expressionQ73536736
Human thyroid fibroblasts exhibit a distinctive phenotype in culture: characteristic ganglioside profile and functional CD40 expressionQ73923154
Peripheral blood fibrocytes: differentiation pathway and migration to wound sitesQ73966720
Functional TSH receptor in human abdominal preadipocytes and orbital fibroblastsQ74061122
Thyrotropin receptor expression in Graves' orbital adipose/connective tissues: potential autoantigen in Graves' ophthalmopathyQ74324679
Sentinel node biopsy for orbital and ocular adnexal tumorsQ74760558
An intrinsic thyrotropin-mediated pathway of TNF-alpha production by bone marrow cellsQ78410308
Real-time PCR provides evidence for thyrotropin receptor mRNA expression in orbital as well as in extraorbital tissuesQ78589378
TSH Is a Negative Regulator of Skeletal RemodelingQ79184844
Thyrotropin receptor knockout mice: studies on immunological tolerance to a major thyroid autoantigenQ79313802
Circulating fibrocytes: collagen-secreting cells of the peripheral bloodQ35686362
Advances in applied anatomy of the eyelid and orbitQ35996567
The peripheral blood fibrocyte is a potent antigen-presenting cell capable of priming naive T cells in situQ36183661
The role of circulating fibrocytes in fibrosisQ36434149
Circulating fibrocytes define a new leukocyte subpopulation that mediates tissue repairQ36437461
Fibrocytes in lung diseaseQ36841197
Unique attributes of orbital fibroblasts and global alterations in IGF-1 receptor signaling could explain thyroid-associated ophthalmopathy.Q36951623
Circulating fibrocytes: cellular basis for NSF.Q37052273
CD34+ fibrocytes: morphology, histogenesis and functionQ37066604
Bone marrow cells produce a novel TSHbeta splice variant that is upregulated in the thyroid following systemic virus infectionQ37069161
Regulation of Lymphocyte Function by PPARgamma: Relevance to Thyroid Eye Disease-Related InflammationQ37114625
Induction of Graves-like disease in mice by immunization with fibroblasts transfected with the thyrotropin receptor and a class II moleculeQ37309918
Evidence for an association between thyroid-stimulating hormone and insulin-like growth factor 1 receptors: a tale of two antigens implicated in Graves' disease.Q37417167
Connective tissue, glycosaminoglycans, and diseases of the thyroidQ38688493
Stressful life events in the pathogenesis of Graves' diseaseQ39428143
Immunological responses in the eyelid and orbitQ39545127
Interaction between Thyroid-Stimulating Immunoglobulins and Thyrotropin Receptors in Fat Cell Membranes*Q40260117
Interleukin-6 is a direct mediator of T cell migrationQ40515648
Association of thyrotrophin receptor antibodies with the clinical features of Graves' ophthalmopathyQ40893670
Long-term follow-up of Graves ophthalmopathy in an incidence cohortQ40994540
Dry eye syndrome in thyroid-associated ophthalmopathy: lacrimal expression of TSH receptor suggests involvement of TSHR-specific autoantibodiesQ42460915
Igs from patients with Graves' disease induce the expression of T cell chemoattractants in their fibroblastsQ43845891
Orbital fibroblast heterogeneity may determine the clinical presentation of thyroid-associated ophthalmopathyQ43853007
Fibroblast subsets in the human orbit: Thy-1+ and Thy-1- subpopulations exhibit distinct phenotypesQ43867818
Immunoglobulins from patients with Graves' disease induce hyaluronan synthesis in their orbital fibroblasts through the self-antigen, insulin-like growth factor-I receptor.Q45096631
IL-1 beta induces IL-6 expression in human orbital fibroblasts: identification of an anatomic-site specific phenotypic attribute relevant to thyroid-associated ophthalmopathy.Q45981776
Immunoglobulin activation of T cell chemoattractant expression in fibroblasts from patients with Graves' disease is mediated through the insulin-like growth factor I receptor pathwayQ46107628
Differentiation of human circulating fibrocytes as mediated by transforming growth factor-beta and peroxisome proliferator-activated receptor gammaQ46224631
The renin-angiotensin system contributes to renal fibrosis through regulation of fibrocytesQ46713511
Bone marrow transplantation demonstrates medullar origin of CD34+ fibrocytes and ameliorates hepatic fibrosis in Abcb4-/- mice.Q50580688
The thyrotropin (thyroid-stimulating hormone) receptor is expressed on murine dendritic cells and on a subset of CD45RBhigh lymph node T cells: functional role for thyroid-stimulating hormone during immune activation.Q52026610
Autologous T-lymphocytes stimulate proliferation of orbital fibroblasts derived from patients with Graves' ophthalmopathy.Q53611171
Characterization of a novel set of resident intrathyroidal bone marrow-derived hematopoietic cells: potential for immune-endocrine interactions in thyroid homeostasis.Q54740671
Correlation of orbital computed tomography and antibodies in patients with hyperthyroid Graves' diseaseQ68522996
Autoimmune thyroid disease: purification and phenotypic analysis of intrathyroid T cellsQ70233713
Evidence for cellular heterogeneity in primary cultures of human orbital fibroblastsQ72055491
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)430-438
P577publication date2009-11-06
P1433published inThe Journal of Clinical Endocrinology and MetabolismQ3186902
P1476titleIncreased generation of fibrocytes in thyroid-associated ophthalmopathy
P478volume95

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cites work (P2860)
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