Orbital fibroblasts from thyroid eye disease patients differ in proliferative and adipogenic responses depending on disease subtype

scientific article

Orbital fibroblasts from thyroid eye disease patients differ in proliferative and adipogenic responses depending on disease subtype is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1167/IOVS.13-12741
P932PMC publication ID3823547
P698PubMed publication ID24135759

P2093author name stringRichard P Phipps
Ajay E Kuriyan
Steven E Feldon
Charles W O'Loughlin
Collynn F Woeller
P2860cites workPeroxisome proliferator-activated receptor-gamma gene expression in orbital adipose/connective tissues is increased during the active stage of Graves' ophthalmopathyQ79231560
Smoking and thyroid-associated ophthalmopathy: A novel explanation of the biological linkQ79259989
Thyroid eye diseaseQ83446693
Graves' ophthalmopathyQ28274196
A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiationQ29619212
Increased generation of fibrocytes in thyroid-associated ophthalmopathyQ33586738
Graves' ophthalmopathy: II. Correlation of clinical signs with measures derived from computed tomographyQ33646613
The eye and thyroid diseaseQ34014090
Quercetin inhibits IL-1β-induced inflammation, hyaluronan production and adipogenesis in orbital fibroblasts from Graves' orbitopathyQ34062319
Novel anti-adipogenic activity produced by human fibroblasts.Q34149741
Imaging in thyroid-associated orbitopathyQ34309119
Cigarette smoke induces cyclooxygenase-2 and microsomal prostaglandin E2 synthase in human lung fibroblasts: implications for lung inflammation and cancerQ34331195
The pathophysiology of thyroid-associated ophthalmopathyQ34684417
Peroxisome proliferator-activated receptor gamma ligands inhibit transforming growth factor-beta-induced, hyaluronan-dependent, T cell adhesion to orbital fibroblastsQ34998187
Activated human T lymphocytes express cyclooxygenase-2 and produce proadipogenic prostaglandins that drive human orbital fibroblast differentiation to adipocytesQ35222158
Thyroid-associated ophthalmopathy: a practical guide to classification, natural history and managementQ35866148
Pathogenesis of graves ophthalmopathy: implications for prediction, prevention, and treatmentQ36525240
Immune mechanisms in thyroid eye disease.Q37254482
Graves' ophthalmopathy: current concepts regarding pathogenesis and managementQ39489563
Electrophilic PPARγ ligands inhibit corneal fibroblast to myofibroblast differentiation in vitro: a potentially novel therapy for corneal scarringQ40430999
Mast cell-derived prostaglandin D2 controls hyaluronan synthesis in human orbital fibroblasts via DP1 activation: implications for thyroid eye diseaseQ40601963
Evidence of fibroblast heterogeneity and the role of fibroblast subpopulations in fibrosisQ40625104
Improvement of thyroid eye disease following treatment with the cyclooxygenase-2 selective inhibitor celecoxibQ42566773
Igs from patients with Graves' disease induce the expression of T cell chemoattractants in their fibroblastsQ43845891
Orbital fibroblast heterogeneity may determine the clinical presentation of thyroid-associated ophthalmopathyQ43853007
Fibroblast subsets in the human orbit: Thy-1+ and Thy-1- subpopulations exhibit distinct phenotypesQ43867818
Eye muscle antibodies and subtype of thyroid-associated ophthalmopathyQ43958341
Association of thy-1 cell surface differentiation antigen with certain connective tissues in vivoQ44421119
Imatinib mesylate and AMN107 inhibit PDGF-signaling in orbital fibroblasts: a potential treatment for Graves' ophthalmopathyQ46113795
Multi-center study on the characteristics and treatment strategies of patients with Graves' orbitopathy: the first European Group on Graves' Orbitopathy experienceQ47945181
Autologous T-lymphocytes stimulate proliferation of orbital fibroblasts derived from patients with Graves' ophthalmopathy.Q53611171
Expression of cyclooxygenase-2 in orbital fibroadipose connective tissues of Graves' ophthalmopathy patients.Q54574733
Ophthalmopathy of Graves' disease: computerized volume measurements of the orbital fat and muscleQ70297118
Evidence for cellular heterogeneity in primary cultures of human orbital fibroblastsQ72055491
Modulation of Graves' orbital fibroblast proliferation by cytokines and glucocorticoid receptor agonistsQ72754868
Expression of hyaluronan synthase messenger ribonucleic acids and their induction by interleukin-1beta in human orbital fibroblasts: potential insight into the molecular pathogenesis of thyroid-associated ophthalmopathyQ73194238
CD40 is a functional activation antigen and B7-independent T cell costimulatory molecule on normal human lung fibroblastsQ73326047
Cytokine profiles in eye muscle tissue and orbital fat tissue from patients with thyroid-associated ophthalmopathyQ73555606
P433issue12
P407language of work or nameEnglishQ1860
P921main subjecteye diseaseQ3041498
P304page(s)7370-7377
P577publication date2013-11-08
P1433published inInvestigative Ophthalmology Visual ScienceQ6060707
P1476titleOrbital fibroblasts from thyroid eye disease patients differ in proliferative and adipogenic responses depending on disease subtype
P478volume54

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cites work (P2860)
Q47814599Complications and outcomes of grafting of posterior orbital fat into the lower lid-cheek junction during orbital decompression
Q27691806Current concepts in the molecular pathogenesis of thyroid-associated ophthalmopathy.
Q51125236Cytokine profiles in clinical subtypes of ophthalmic Graves' disease.
Q40095263Dysthyroid optic neuropathy: update on pathogenesis, diagnosis, and management
Q90894014Interruption of autoimmunity for thyroid eye disease: B-cell and T-cell strategy
Q38293593Management of strabismus in thyroid eye disease
Q35738996Normal Human Lung Epithelial Cells Inhibit Transforming Growth Factor-β Induced Myofibroblast Differentiation via Prostaglandin E2
Q38633022Pathogenesis of thyroid eye disease: review and update on molecular mechanisms.
Q47114849Quantitative Analysis of Inflammation in Orbital Fat of Thyroid-associated Ophthalmopathy Using MRI Signal Intensity
Q47121440RNA-Sequencing Gene Expression Profiling of Orbital Adipose-Derived Stem Cell Population Implicate HOX Genes and WNT Signaling Dysregulation in the Pathogenesis of Thyroid-Associated Orbitopathy
Q36833918Relationship between magnetic resonance imaging signal intensity and volume of extraocular muscles in thyroid-associated ophthalmopathy with methylprednisolone pulse therapy
Q35055573Salinomycin and other polyether ionophores are a new class of antiscarring agent
Q36738202Severe Ophthalmological Complications of Thyroid Disease are Rare in Ibadan, Southwestern Nigeria: Results of a Pilot Study
Q35900410Surgical Responses of Medial Rectus Muscle Recession in Thyroid Eye Disease-Related Esotropia
Q38795531The Aryl Hydrocarbon Receptor and Its Ligands Inhibit Myofibroblast Formation and Activation: Implications for Thyroid Eye Disease
Q95322318The aryl hydrocarbon receptor pathway controls matrix metalloproteinase-1 and collagen levels in human orbital fibroblasts

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