Interruption of autoimmunity for thyroid eye disease: B-cell and T-cell strategy

scientific article published on 04 January 2019

Interruption of autoimmunity for thyroid eye disease: B-cell and T-cell strategy is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/S41433-018-0315-9
P932PMC publication ID6367473
P698PubMed publication ID30610229

P2093author name stringFrancesca Rossi
Diego Strianese
P2860cites workBreaking tolerance to thyroid antigens: changing concepts in thyroid autoimmunityQ26852013
Autoimmunity and Graves' diseaseQ27022771
Current concepts in the molecular pathogenesis of thyroid-associated ophthalmopathy.Q27691806
MANAGEMENT OF ENDOCRINE DISEASE: Rituximab therapy for Graves' orbitopathy - lessons from randomized control trialsQ28077018
Antiinflammatory action of glucocorticoids--new mechanisms for old drugsQ28278037
Protocol for the combined immunosuppression & radiotherapy in thyroid eye disease (CIRTED) trial: a multi-centre, double-masked, factorial randomised controlled trialQ30481543
Germinal center selection and the development of memory B and plasma cellsQ34268133
B-cell biology and developmentQ34331269
Teprotumumab for Thyroid-Associated Ophthalmopathy.Q34556184
Unilateral proptosis in thyroid eye disease with subsequent contralateral involvement: retrospective follow-up studyQ34747393
A stimulatory TSH receptor antibody enhances adipogenesis via phosphoinositide 3-kinase activation in orbital preadipocytes from patients with Graves' ophthalmopathy.Q34782210
Efficacy of B-cell targeted therapy with rituximab in patients with active moderate to severe Graves' orbitopathy: a randomized controlled study.Q35055076
Randomized controlled trial of rituximab in patients with Graves' orbitopathyQ35055124
Immunopathogenesis of Graves' ophthalmopathy: the role of the TSH receptorQ35992560
Axial Globe Position Measurement: A Prospective Multicenter Study by the International Thyroid Eye Disease Society.Q35995565
Pathogenesis of graves ophthalmopathy: implications for prediction, prevention, and treatmentQ36525240
Avoiding surgery for thyroid eye diseaseQ36613471
A small molecule antagonist inhibits thyrotropin receptor antibody-induced orbital fibroblast functions involved in the pathogenesis of Graves ophthalmopathyQ36817224
Clinical review: Clinical utility of TSH receptor antibodiesQ36885833
Pathogenesis of Graves' ophthalmopathy: the role of autoantibodiesQ36970632
Role of insulin-like growth factor-1 (IGF-1) pathway in the pathogenesis of Graves' orbitopathy.Q37017174
Immune mechanisms in thyroid eye disease.Q37254482
Orbital fibroblasts from thyroid eye disease patients differ in proliferative and adipogenic responses depending on disease subtypeQ37296579
The type 1 insulin-like growth factor receptor pathwayQ37300867
Orbital fibroblasts from patients with thyroid-associated ophthalmopathy overexpress CD40: CD154 hyperinduces IL-6, IL-8, and MCP-1.Q37363607
Evidence for an association between thyroid-stimulating hormone and insulin-like growth factor 1 receptors: a tale of two antigens implicated in Graves' disease.Q37417167
Thyroid-associated orbitopathy: who and how to treatQ37425768
Methotrexate for the treatment of thyroid eye diseaseQ37616156
Memory B and memory plasma cellsQ37781393
Clinical review: Intravenous glucocorticoids for Graves' orbitopathy: efficacy and morbidityQ37829150
Decisions on the road to memoryQ38086164
Thyrotropin receptor activation increases hyaluronan production in preadipocyte fibroblasts: contributory role in hyaluronan accumulation in thyroid dysfunction.Q38351966
Advances in treatment of active, moderate-to-severe Graves' ophthalmopathyQ38877933
Radiotherapy for the treatment of thyroid eye disease-a prospective comparison: Is orbital radiotherapy a suitable alternative to steroids?Q39041665
Adalimumab as steroid-sparing treatment of inflammatory-stage thyroid eye diseaseQ39167512
Update on Graves disease: advances in treatment of mild, moderate and severe thyroid eye diseaseQ39430686
Association of thyrotrophin receptor antibodies with the clinical features of Graves' ophthalmopathyQ40893670
Analysis of extraocular muscle-infiltrating T cells in thyroid-associated ophthalmopathy (TAO).Q41096678
Age and Dose Are Major Risk Factors for Liver Damage Associated with Intravenous Glucocorticoid Pulse Therapy for Graves' OrbitopathyQ41657253
The role of CXCR4 in maintaining peripheral B cell compartments and humoral immunityQ41876450
The critical role of Shc in insulin-like growth factor-I-mediated mitogenesis and differentiation in 3T3-L1 preadipocytesQ42801077
Fibroblast subsets in the human orbit: Thy-1+ and Thy-1- subpopulations exhibit distinct phenotypesQ43867818
Immunoglobulins from patients with Graves' disease induce hyaluronan synthesis in their orbital fibroblasts through the self-antigen, insulin-like growth factor-I receptor.Q45096631
Clinical Response to Tocilizumab in Severe Thyroid Eye DiseaseQ46188153
Randomized, single blind trial of intravenous versus oral steroid monotherapy in Graves' orbitopathyQ46585048
Orbital B-lymphocyte depletion in a treatment failure of rituximab for thyroid eye diseaseQ46906161
Analysis of orbital T cells in thyroid-associated ophthalmopathyQ47901537
Combined immunosuppression and radiotherapy in thyroid eye disease (CIRTED): a multicentre, 2 × 2 factorial, double-blind, randomised controlled trial.Q49360082
Soft Tissue Metrics in Thyroid Eye Disease: An International Thyroid Eye Disease Society Reliability Study.Q49712817
Safety and efficacy of combined immunosuppression and orbital radiotherapy in thyroid-related restrictive myopathy: two-center experience.Q50701679
Reliability of estimating ductions in thyroid eye disease: an International Thyroid Eye Disease Society multicenter study.Q51852266
Plasma cell survival is mediated by synergistic effects of cytokines and adhesion-dependent signals.Q52950179
Efficacy and safety of mycophenolate mofetil in patients with active moderate-to-severe Graves' orbitopathy.Q53057871
Distinct effector cytokine profiles of memory and naive human B cell subsets and implication in multiple sclerosis.Q53555780
Autologous T-lymphocytes stimulate proliferation of orbital fibroblasts derived from patients with Graves' ophthalmopathy.Q53611171
Adrenal reserve following treatment of Graves' orbitopathy with intravenous glucocorticoids.Q53634232
Comparison of intravenous methylprednisolone therapy vs. oral methylprednisolone therapy in patients with Graves' ophthalmopathy.Q53758474
Insulin-like growth factor 1 promotes the proliferation and adipogenesis of orbital adipose-derived stromal cells in thyroid-associated ophthalmopathy.Q54280456
Efficacy and Safety of Three Different Cumulative Doses of Intravenous Methylprednisolone for Moderate to Severe and Active Graves' OrbitopathyQ58109526
Infliximab: A Novel Treatment for Sight-Threatening Thyroid Associated OphthalmopathyQ60207430
Fatal and non-fatal adverse events of glucocorticoid therapy for Graves' orbitopathy: a questionnaire survey among members of the European Thyroid AssociationQ60604183
Orbital cobalt irradiation combined with retrobulbar or systemic corticosteroids for Graves' ophthalmopathy: a comparative studyQ68187821
Azathioprine in the treatment of thyroid-associated ophthalmopathyQ68713064
Prednisone and cyclosporine in the treatment of severe Graves' ophthalmopathyQ69288448
Detection of TSH receptor RNA in cultured fibroblasts from patients with Graves' ophthalmopathy and pretibial dermopathyQ71612410
Expression of thyrotropin-receptor mRNA in healthy and Graves' disease retro-orbital tissueQ72226506
Thyrotropin receptor expression in cultured Graves' orbital preadipocyte fibroblasts is stimulated by thyrotropinQ74336335
Dominant infiltration of T(H)1-type CD4+ T cells at the retrobulbar space of patients with thyroid-associated ophthalmopathyQ77351739
The effect of etanercept on Graves' ophthalmopathy: a pilot studyQ81024281
Insulin-like growth factor-1 potentiates platelet activation via the IRS/PI3Kalpha pathwayQ81163093
Failure of rituximab treatment in a case of severe thyroid ophthalmopathy unresponsive to steroidsQ82359524
Orbit-infiltrating mast cells, monocytes, and macrophages produce PDGF isoforms that orchestrate orbital fibroblast activation in Graves' ophthalmopathyQ83216077
Thyrotropin receptor-stimulating Graves' disease immunoglobulins induce hyaluronan synthesis by differentiated orbital fibroblasts from patients with Graves' ophthalmopathy not only via cyclic adenosine monophosphate signaling pathwaysQ85211682
Treatment of active corticosteroid-resistant graves' orbitopathyQ87246219
Efficacy of Tocilizumab in Patients With Moderate-to-Severe Corticosteroid-Resistant Graves Orbitopathy: A Randomized Clinical TrialQ90775985
P433issue2
P921main subjecteye diseaseQ3041498
P304page(s)191-199
P577publication date2019-01-04
P1433published inEyeQ10278937
P1476titleInterruption of autoimmunity for thyroid eye disease: B-cell and T-cell strategy
P478volume33

Search more.