| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S0168-9525(98)01689-8 |
| P698 | PubMed publication ID | 10203800 |
| P50 | author | John M. Sedivy | Q21062965 |
| P2093 | author name string | Dutriaux A | |
| P2860 | cites work | DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes | Q22007974 |
| Transactivation-defective c-MycS retains the ability to regulate proliferation and apoptosis | Q28292481 | ||
| Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes | Q29547355 | ||
| Requirement for p53 and p21 to sustain G2 arrest after DNA damage | Q29547667 | ||
| Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome | Q29617396 | ||
| Positive genetic selection for gene disruption in mammalian cells by homologous recombination | Q33829038 | ||
| c-myc null cells misregulate cad and gadd45 but not other proposed c-Myc targets | Q35212190 | ||
| Internal translation initiation in the design of improved expression vectors | Q35303150 | ||
| Targeted homologous recombination in mammalian cells | Q35898245 | ||
| Recycling selectable markers in mouse embryonic stem cells | Q36558820 | ||
| Analysis of biological selections for high-efficiency gene targeting | Q36566296 | ||
| Production of homozygous mutant ES cells with a single targeting construct | Q36815597 | ||
| Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs | Q37045150 | ||
| Homologous recombination in mammalian cells | Q38763375 | ||
| On the nature of hereditable variation in cultured somatic cells | Q40555367 | ||
| Reduced X-ray resistance and homologous recombination frequencies in a RAD54-/- mutant of the chicken DT40 cell line | Q41115358 | ||
| Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts | Q42815554 | ||
| Gene targeting in normal somatic cells: inactivation of the interferon-gamma receptor in myoblasts | Q45872568 | ||
| Homologous integration in mammalian cells without target gene selection | Q64390239 | ||
| P433 | issue | 3 | |
| P921 | main subject | gene targeting | Q211083 |
| P304 | page(s) | 88-90 | |
| P577 | publication date | 1999-03-01 | |
| P1433 | published in | Trends in Genetics | Q2451468 |
| P1476 | title | Gene targeting and somatic cell genetics--a rebirth or a coming of age? | |
| P478 | volume | 15 |
| Q39687331 | A chromosomal position effect on gene targeting in human cells |
| Q39572588 | A novel method for constructing gene-targeting vectors |
| Q34437072 | A one-step cloning method for the construction of somatic cell gene targeting vectors: application to production of human knockout cell lines |
| Q24536135 | A role for RAD54B in homologous recombination in human cells |
| Q33884014 | A somatic knockout of CBF1 in a human B-cell line reveals that induction of CD21 and CCR7 by EBNA-2 is strictly CBF1 dependent and that downregulation of immunoglobulin M is partially CBF1 independent |
| Q33910919 | AIF suppresses chemical stress-induced apoptosis and maintains the transformed state of tumor cells |
| Q36109764 | Animal embryonic stem (ES) cells: self-renewal, pluripotency, transgenesis and nuclear transfer |
| Q51819891 | Cloning livestock: a return to embryonic cells. |
| Q40695618 | Construction of long DNA molecules using long PCR-based fusion of several fragments simultaneously |
| Q24803689 | Creation of non-human primate neurogenetic disease models by gene targeting and nuclear transfer |
| Q42172793 | Development of a porcine model of cystic fibrosis. |
| Q36642451 | Development of human gene reporter cell lines using rAAV mediated homologous recombination |
| Q34111011 | Dynamic plasticity of large-scale chromatin structure revealed by self-assembly of engineered chromosome regions |
| Q40770823 | Efficient recruitment of transfected DNA to a homologous chromosomal target in mammalian cells |
| Q41867231 | Enhancement of extra chromosomal recombination in somatic cells by affecting the ratio of homologous recombination (HR) to non-homologous end joining (NHEJ). |
| Q36112304 | Enhancing gene targeting efficiency in higher plants: rice is on the move |
| Q24633989 | Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses |
| Q37552793 | Gene targeting from laboratory to livestock: current status and emerging concepts. |
| Q34168037 | Gene targeting in Physcomitrella patens |
| Q33325792 | Gene targeting in adult rhesus macaque fibroblasts. |
| Q27317372 | Generation of Double-Labeled Reporter Cell Lines for Studying Co-Dynamics of Endogenous Proteins in Individual Human Cells |
| Q47848328 | Generation of β-lactoglobulin-modified transgenic goats by homologous recombination. |
| Q34001661 | Genetic analysis of homologous DNA recombination in vertebrate somatic cells |
| Q40050373 | Genetic knockouts and knockins in human somatic cells |
| Q51726574 | Harvesting the genomic promise: recombineering sequences for phenotypes. |
| Q35604547 | Homologous recombination and gene targeting in plant cells |
| Q37974988 | Homologous recombination-based gene therapy for the primary immunodeficiencies |
| Q40430437 | Hyperphosphorylation of the BARD1 tumor suppressor in mitotic cells |
| Q37415432 | Hypersensitivities for acetaldehyde and other agents among cancer cells null for clinically relevant Fanconi anemia genes |
| Q24535648 | Improved methods for the generation of human gene knockout and knockin cell lines |
| Q41936505 | Inverted terminal repeats of adeno-associated virus decrease random integration of a gene targeting fragment in Saccharomyces cerevisiae. |
| Q35730832 | Jurkat T cells and development of the T-cell receptor signalling paradigm |
| Q34250440 | Loss of retinoblastoma but not p16 function allows bypass of replicative senescence in human fibroblasts |
| Q34311686 | Manipulating the mammalian genome by homologous recombination |
| Q39126523 | May I Cut in? Gene Editing Approaches in Human Induced Pluripotent Stem Cells |
| Q30320137 | Minimal Extent of Sequence Homology Required for Homologous Recombination at the psbA Locus in Chlamydomonas reinhardtii Chloroplasts using PCR-generated DNA Fragments |
| Q33828398 | Mouse Rad1 deletion enhances susceptibility for skin tumor development |
| Q34242706 | Mutant T cell lines as model systems for the dissection of T cell antigen receptor signaling pathways |
| Q33873896 | New advances in somatic cell nuclear transfer: application in transgenesis |
| Q34466910 | Nuclear transfer technology in mammalian cloning. |
| Q34680921 | Pig endogenous retroviruses and xenotransplantation |
| Q35095655 | Plant genome modification by homologous recombination |
| Q39648299 | Pleiotropic defects in TCR signaling in a Vav-1-null Jurkat T-cell line. |
| Q34098319 | Precursor cells for transplantation |
| Q28271767 | Production of CFTR-null and CFTR-DeltaF508 heterozygous pigs by adeno-associated virus-mediated gene targeting and somatic cell nuclear transfer |
| Q48830864 | Production of alpha 1,3-galactosyltransferase-knockout cloned pigs expressing human alpha 1,2-fucosylosyltransferase |
| Q28140542 | Production of gene-targeted sheep by nuclear transfer from cultured somatic cells |
| Q48938785 | Production of heterozygous alpha 1,3-galactosyltransferase (GGTA1) knock-out transgenic miniature pigs expressing human CD39. |
| Q33737226 | Prospects for the precise engineering of plant genomes by homologous recombination. |
| Q34428260 | Rescue the failed half-ZFN by a sensitive mammalian cell-based luciferase reporter system |
| Q35105072 | Screening of HaCaT clones for CCL20 gene knockout and preliminary exploration of gene-targeting vector transfection approaches in this cell line |
| Q46337068 | Sequential targeting of the genes encoding immunoglobulin-mu and prion protein in cattle |
| Q34443086 | Simple monitoring of gene targeting efficiency in human somatic cell lines using the PIGA gene |
| Q24801067 | Specific genetic modifications of domestic animals by gene targeting and animal cloning |
| Q40343671 | Stability and homogeneity of transgene expression in isogenic cells |
| Q33702173 | TALEN-mediated genetic tailoring as a tool to analyze the function of acquired mutations in multiple myeloma cells |
| Q40709912 | Target disruption of the mutant beta-catenin gene in colon cancer cell line HCT116: preservation of its malignant phenotype |
| Q36846439 | The porcine lung as a potential model for cystic fibrosis |
| Q26773287 | Towards a new era in medicine: therapeutic genome editing |
| Q33937871 | Transgenic livestock: premises and promises |
| Q28511980 | Tumor necrosis factor receptor-associated factor 2 (TRAF2)-deficient B lymphocytes reveal novel roles for TRAF2 in CD40 signaling |
| Q34310079 | Use of single stranded targeting DNA or negative selection does not further increase the efficiency of a GGTA1 promoter trap |
| Q34043465 | VEGFR2 translocates to the nucleus to regulate its own transcription |
| Q33839295 | XRCC1 keeps DNA from getting stranded |
| Q37118845 | Zinc-finger nuclease-mediated gene correction using single AAV vector transduction and enhancement by Food and Drug Administration-approved drugs |
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