scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1084954791 |
P356 | DOI | 10.1038/SREP46751 |
P932 | PMC publication ID | 5402287 |
P698 | PubMed publication ID | 28436464 |
P50 | author | Peter Oladimeji | Q95985385 |
P2093 | author name string | Taosheng Chen | |
Wenwei Lin | |||
Peter O Oladimeji | |||
C Trent Brewer | |||
P2860 | cites work | The blooming of the French lilac | Q22241897 |
Role of AMP-activated protein kinase in mechanism of metformin action | Q22241898 | ||
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress | Q24633606 | ||
The selectivity of protein kinase inhibitors: a further update | Q24654622 | ||
Role of pregnane X receptor in chemotherapeutic treatment | Q26827398 | ||
The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity | Q27632611 | ||
PXR and CAR in energy metabolism | Q28251686 | ||
An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway | Q28263744 | ||
AMP-activated protein kinase mediates phenobarbital induction of CYP2B gene expression in hepatocytes and a newly derived human hepatoma cell line | Q28295835 | ||
The ER UDPase ENTPD5 promotes protein N-glycosylation, the Warburg effect, and proliferation in the PTEN pathway | Q28298223 | ||
LKB1 is the upstream kinase in the AMP-activated protein kinase cascade | Q28610414 | ||
AMPK: a nutrient and energy sensor that maintains energy homeostasis | Q29615410 | ||
Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism | Q29617479 | ||
The LKB1-AMPK pathway: metabolism and growth control in tumour suppression | Q29617506 | ||
5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells? | Q29618095 | ||
AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy | Q29618101 | ||
Pharmacogenomics: translating functional genomics into rational therapeutics | Q33751829 | ||
A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipogenic pathway | Q33945905 | ||
The specificities of small molecule inhibitors of the TGFß and BMP pathways | Q33956096 | ||
Development of BODIPY FL vindoline as a novel and high-affinity pregnane X receptor fluorescent probe | Q34196976 | ||
First-pass elimination. Basic concepts and clinical consequences | Q34257205 | ||
Pregnane X Receptor and Constitutive Androstane Receptor at the Crossroads of Drug Metabolism and Energy Metabolism | Q34359458 | ||
The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism | Q34525699 | ||
Differential drug resistance acquisition to doxorubicin and paclitaxel in breast cancer cells | Q34787556 | ||
Identification of genes controlled by the pregnane X receptor by microarray analysis of mRNAs from pregnenolone 16alpha-carbonitrile-treated rats | Q35131177 | ||
Dietary Effects on Drug Metabolism and Transport | Q35553197 | ||
Differential effect of type I and type II diabetes on antipyrine disposition in man | Q68466207 | ||
Hepatic drug metabolism is increased in poorly controlled insulin-dependent diabetes mellitus | Q68628566 | ||
Enhancement of antitumor activity of mitomycin C in vitro and in vivo by UCN-01, a selective inhibitor of protein kinase C | Q70733013 | ||
T0901317 is a potent PXR ligand: implications for the biology ascribed to LXR | Q80120308 | ||
AMPK potentiates hypertonicity-induced apoptosis by suppressing NFκB/COX-2 in medullary interstitial cells | Q35758306 | ||
The camKK2/camKIV relay is an essential regulator of hepatic cancer | Q35889308 | ||
Regulation of drug resistance by human pregnane X receptor in breast cancer | Q36083299 | ||
Calcium calmodulin dependent kinase kinase 2 - a novel therapeutic target for gastric adenocarcinoma | Q36213122 | ||
Calcium/calmodulin-dependent protein kinase kinase 2: roles in signaling and pathophysiology | Q36234679 | ||
Role of AMP-activated protein kinase in cross-talk between apoptosis and autophagy in human colon cancer | Q36291183 | ||
Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase. | Q36301403 | ||
AMPK governs lineage specification through Tfeb-dependent regulation of lysosomes | Q36661543 | ||
Nuclear receptors and the regulation of drug-metabolizing enzymes and drug transporters: implications for interindividual variability in response to drugs | Q36795136 | ||
Long-term exposure to abnormal glucose levels alters drug metabolism pathways and insulin sensitivity in primary human hepatocytes | Q37014966 | ||
A vinblastine fluorescent probe for pregnane X receptor in a time-resolved fluorescence resonance energy transfer assay | Q37303129 | ||
LKB1; linking cell structure and tumor suppression | Q37333592 | ||
The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism | Q37400616 | ||
Nuclear receptors CAR and PXR cross talk with FOXO1 to regulate genes that encode drug-metabolizing and gluconeogenic enzymes | Q37493137 | ||
Metformin represses drug-induced expression of CYP2B6 by modulating the constitutive androstane receptor signaling | Q37553490 | ||
P-glycoprotein: a major determinant of rifampicin-inducible expression of cytochrome P4503A in mice and humans | Q37626608 | ||
The AMPK inhibitor compound C is a potent AMPK-independent antiglioma agent | Q37637656 | ||
Nuclear receptors PXR and CAR: implications for drug metabolism regulation, pharmacogenomics and beyond | Q38074718 | ||
Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome | Q38312576 | ||
AMPK: An Energy-Sensing Pathway with Multiple Inputs and Outputs | Q38652124 | ||
Inhibition of pregnane X receptor pathway contributes to the cell growth inhibition and apoptosis of anticancer agents in ovarian cancer cells | Q38749288 | ||
AMPK and PKA interaction in the regulation of survival of liver cancer cells subjected to glucose starvation. | Q38792676 | ||
Salicylate activates AMPK and synergizes with metformin to reduce the survival of prostate and lung cancer cells ex vivo through inhibition of de novo lipogenesis. | Q38879155 | ||
SCD1 negatively regulates autophagy-induced cell death in human hepatocellular carcinoma through inactivation of the AMPK signaling pathway | Q38926671 | ||
Physicochemical characterization and in vitro permeation of an indirubin derivative | Q39101885 | ||
Dorsomorphin and LDN-193189 inhibit BMP-mediated Smad, p38 and Akt signalling in C2C12 cells. | Q39670303 | ||
Cyclin-dependent kinase 2 negatively regulates human pregnane X receptor-mediated CYP3A4 gene expression in HepG2 liver carcinoma cells | Q39941217 | ||
Inhibition of ABCB1 (MDR1) and ABCB4 (MDR3) expression by small interfering RNA and reversal of paclitaxel resistance in human ovarian cancer cells. | Q40536091 | ||
A physiological role of AMP-activated protein kinase in phenobarbital-mediated constitutive androstane receptor activation and CYP2B induction | Q42156016 | ||
ATP Consumption Promotes Cancer Metabolism | Q42791522 | ||
Chemoprevention meets glucose control | Q42920178 | ||
5-aminoimidazole-4-carboxamide-1-beta-ribofuranoside (AICAR) prevents nuclear translocation of constitutive androstane receptor by AMP-activated protein kinase (AMPK) independent manner. | Q42945903 | ||
Different expression of hepatic and renal cytochrome P450s between the streptozotocin-induced diabetic mouse and rat. | Q43682845 | ||
Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification | Q44104285 | ||
Genetic profiling defines the xenobiotic gene network controlled by the nuclear receptor pregnane X receptor | Q44381593 | ||
1-Acyl-1H-[1,2,4]triazole-3,5-diamine analogues as novel and potent anticancer cyclin-dependent kinase inhibitors: synthesis and evaluation of biological activities | Q46563138 | ||
Activation of AMP-activated protein kinase induces p53-dependent apoptotic cell death in response to energetic stress | Q46868426 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 46751 | |
P577 | publication date | 2017-04-24 | |
P1433 | published in | Scientific Reports | Q2261792 |
P1476 | title | Glucose-dependent regulation of pregnane X receptor is modulated by AMP-activated protein kinase | |
P478 | volume | 7 |
Q47166492 | Hepatotoxicity of Herbal Supplements Mediated by Modulation of Cytochrome P450. |
Q50122109 | High-Throughput Screening Identifies 1,4,5-Substituted 1,2,3-Triazole Analogs as Potent and Specific Antagonists of Pregnane X Receptor |
Q89455144 | KANSL2 and MBNL3 are regulators of pancreatic ductal adenocarcinoma invasion |
Q91272344 | Nutritional status modifies pregnane X receptor regulated transcriptome |
Q90281157 | The Isoniazid Metabolites Hydrazine and Pyridoxal Isonicotinoyl Hydrazone Modulate Heme Biosynthesis |
Q88669494 | The Roles of Xenobiotic Receptors: Beyond Chemical Disposition |
Q50056522 | Using TR-FRET to Investigate Protein-Protein Interactions: A Case Study of PXR-Coregulator Interaction |
Search more.