| scholarly article | Q13442814 |
| P819 | ADS bibcode | 1998PNAS...9515559B |
| P356 | DOI | 10.1073/PNAS.95.26.15559 |
| P932 | PMC publication ID | 28082 |
| P698 | PubMed publication ID | 9861008 |
| P5875 | ResearchGate publication ID | 13426823 |
| P2093 | author name string | D B Roth | |
| M A Bogue | |||
| C Jhappan | |||
| P2860 | cites work | DNA end-joining catalyzed by human cell-free extracts | Q22008041 |
| Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells | Q24320116 | ||
| Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV | Q24323238 | ||
| DNA-PK is essential only for coding joint formation in V(D)J recombination | Q39724861 | ||
| DNA breakage and repair | Q40849877 | ||
| DNA-dependent protein kinase acts upstream of p53 in response to DNA damage | Q41013003 | ||
| Ku70: a candidate tumor suppressor gene for murine T cell lymphoma | Q41017020 | ||
| Murine cell line SX9 bearing a mutation in the dna-pkcs gene exhibits aberrant V(D)J recombination not only in the coding joint but also in the signal joint | Q41040365 | ||
| A kinase-negative mutation of DNA-PK(CS) in equine SCID results in defective coding and signal joint formation | Q41116024 | ||
| Characterization of two DNA double-stranded break repair-deficient cell lines that express inactive DNA-dependent protein kinase catalytic subunits | Q41116291 | ||
| An ionizing radiation-sensitive CHO mutant cell line: irs-20. IV. Genetic complementation, V(D)J recombination and the scid phenotype | Q41131832 | ||
| Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line | Q41368190 | ||
| Recent advances in understanding V(D)J recombination. | Q41430421 | ||
| V(D)J recombination in mammalian cell mutants defective in DNA double-strand break repair | Q41549015 | ||
| Impairment of V(D)J recombination in double-strand break repair mutants | Q41560292 | ||
| V(D)J recombination generates a high frequency of nonstandard TCR D delta-associated rearrangements in thymocytes. | Q42615873 | ||
| DNA-PKcs: a T-cell tumour suppressor encoded at the mouse scid locus | Q42833970 | ||
| The scid defect affects the final step of the immunoglobulin VDJ recombinase mechanism | Q44009684 | ||
| Telomere maintenance is dependent on activities required for end repair of double-strand breaks | Q47946099 | ||
| The defect in murine severe combined immune deficiency: joining of signal sequences but not coding segments in V(D)J recombination | Q48313594 | ||
| Rejoining of DNA by the RAG1 and RAG2 proteins | Q49172612 | ||
| Growth retardation and leaky SCID phenotype of Ku70-deficient mice. | Q52191949 | ||
| Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency. | Q53534567 | ||
| The scid mutation in mice causes a general defect in DNA repair | Q59073681 | ||
| V(D)J recombination in mouse thymocytes: Double-strand breaks near T cell receptor δ rearrangement signals | Q64389915 | ||
| V(D)J recombination: broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes | Q67521111 | ||
| T-lymphocyte development in scid mice is arrested shortly after the initiation of T-cell receptor delta gene recombination | Q67940431 | ||
| p53 is required for both radiation-induced differentiation and rescue of V(D)J rearrangement in scid mouse thymocytes | Q70993632 | ||
| Characterization of coding ends in thymocytes of scid mice: Implications for the mechanism of V(D)J recombination | Q71843533 | ||
| V(D)J recombination in Ku86-deficient mice: distinct effects on coding, signal, and hybrid joint formation | Q73574910 | ||
| A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination | Q77398644 | ||
| Saccharomyces cerevisiae LIF1: a function involved in DNA double-strand break repair related to mammalian XRCC4. | Q27938296 | ||
| Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination | Q28243620 | ||
| The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination | Q28272412 | ||
| A severe combined immunodeficiency mutation in the mouse | Q28274531 | ||
| RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination | Q28307236 | ||
| DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect | Q28307262 | ||
| Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity | Q28506163 | ||
| Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acids | Q28608946 | ||
| The DNA-binding protein Hdf1p (a putative Ku homologue) is required for maintaining normal telomere length in Saccharomyces cerevisiae | Q29465403 | ||
| Molecular and biochemical characterisation of DNA-dependent protein kinase-defective rodent mutant irs-20 | Q32082716 | ||
| Equine severe combined immunodeficiency: a defect in V(D)J recombination and DNA-dependent protein kinase activity. | Q33702830 | ||
| Interaction of DNA-dependent protein kinase with DNA and with Ku: biochemical and atomic-force microscopy studies | Q33887333 | ||
| Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks | Q33888149 | ||
| Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation. | Q34320792 | ||
| Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance | Q34411525 | ||
| Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells | Q34419609 | ||
| XR-C1, a new CHO cell mutant which is defective in DNA-PKcs, is impaired in both V(D)J coding and signal joint formation | Q34669732 | ||
| Enhancer control of V(D)J recombination at the TCRbeta locus: differential effects on DNA cleavage and joining | Q35206945 | ||
| DNA-dependent protein kinase: DNA binding and activation in the absence of Ku | Q35739034 | ||
| Oligonucleotide capture during end joining in mammalian cells | Q35887410 | ||
| Nonsense mutation at Tyr-4046 in the DNA-dependent protein kinase catalytic subunit of severe combined immune deficiency mice | Q36044979 | ||
| Ku70 is required for DNA repair but not for T cell antigen receptor gene recombination In vivo | Q36380622 | ||
| scid cells are deficient in Ku and replication protein A phosphorylation by the DNA-dependent protein kinase | Q36555430 | ||
| Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes | Q36562716 | ||
| Ku86 is not required for protection of signal ends or for formation of nonstandard V(D)J recombination products | Q36567784 | ||
| Biased T-cell receptor delta element recombination in scid thymocytes | Q36686717 | ||
| Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse | Q36820879 | ||
| The SCID mouse mutant: definition, characterization, and potential uses | Q37357870 | ||
| scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair | Q37404182 | ||
| A link between double-strand break-related repair and V(D)J recombination: the scid mutation | Q37508055 | ||
| V(D)J recombination intermediates and non-standard products in XRCC4-deficient cells | Q38335020 | ||
| A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage | Q38349361 | ||
| Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates | Q38354165 | ||
| Requirement for Ku80 in growth and immunoglobulin V(D)J recombination | Q38354221 | ||
| P433 | issue | 26 | |
| P407 | language of work or name | English | Q1860 |
| P1104 | number of pages | 6 | |
| P304 | page(s) | 15559-15564 | |
| P577 | publication date | 1998-12-01 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Analysis of variable (diversity) joining recombination in DNAdependent protein kinase (DNA-PK)-deficient mice reveals DNA-PK-independent pathways for both signal and coding joint formation | |
| P478 | volume | 95 |
| Q42146685 | A hypomorphic Artemis human disease allele causes aberrant chromosomal rearrangements and tumorigenesis |
| Q40855966 | A new X-ray sensitive CHO cell mutant of ionizing radiation group 7,XR-C2, that is defective in DSB repair but has only a mild defect in V(D)J recombination. |
| Q34805011 | Aberrant V(D)J recombination in ataxia telangiectasia mutated-deficient lymphocytes is dependent on nonhomologous DNA end joining. |
| Q33965750 | Activation of V(D)J recombination induces the formation of interlocus joints and hybrid joints in scid pre-B-cell lines |
| Q34550115 | Ataxia telangiectasia mutated (Atm) and DNA-PKcs kinases have overlapping activities during chromosomal signal joint formation |
| Q27919641 | Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair |
| Q37063328 | DNA damage and repair during lymphoid development: antigen receptor diversity, genomic integrity and lymphomagenesis |
| Q36371923 | DNA-dependent protein kinase activity is not required for immunoglobulin class switching |
| Q38077808 | DNA-dependent protein kinase and its inhibition in support of radiotherapy |
| Q58591000 | Deciphering phenotypic variance in different models of DNA-PKcs deficiency |
| Q35054512 | Effect of DNA-dependent protein kinase on the molecular fate of the rAAV2 genome in skeletal muscle |
| Q96135452 | Effects of the scid mutation on X-ray-induced deletions in the brain and spleen of gpt delta mice |
| Q36845675 | Evolution of the immunoglobulin heavy chain class switch recombination mechanism |
| Q51829783 | Healing the wounds inflicted by sleeping beauty transposition by double-strand break repair in mammalian somatic cells. |
| Q32067274 | How to make ends meet in V(D)J recombination |
| Q77995587 | IgH class switch recombination to IgG1 in DNA-PKcs-deficient B cells |
| Q52107361 | In vivo ligation of CD3 on neonatal scid thymocytes blocks gamma-irradiation-induced TCRbeta rearrangements and thymic lymphomagenesis. |
| Q40758604 | Increased accumulation of hybrid V(D)J joins in cells expressing truncated versus full-length RAGs. |
| Q33966818 | Irradiation promotes V(D)J joining and RAG-dependent neoplastic transformation in SCID T-cell precursors |
| Q73427951 | Joining-deficient RAG1 mutants block V(D)J recombination in vivo and hairpin opening in vitro |
| Q24554252 | Ku recruits the XRCC4-ligase IV complex to DNA ends |
| Q28137885 | Ku, a DNA repair protein with multiple cellular functions? |
| Q24527652 | Ku86 autoantigen related protein-1 transcription initiates from a CpG island and is induced by p53 through a nearby p53 response element |
| Q33894543 | Ku86 is essential in human somatic cells |
| Q36037736 | Mechanism and control of V(D)J recombination versus class switch recombination: similarities and differences |
| Q44982147 | Non-homologous end joining requires that the DNA-PK complex undergo an autophosphorylation-dependent rearrangement at DNA ends. |
| Q47677812 | Paradigm switching in the germinal center. |
| Q48215784 | Paradoxical decrease in mutant frequencies and chromosomal rearrangements in a transgenic lacZ reporter gene in Ku80 null mice deficient in DNA double strand break repair |
| Q33558920 | RAG2's acidic hinge restricts repair-pathway choice and promotes genomic stability |
| Q34181022 | Regulation of telomere length and suppression of genomic instability in human somatic cells by Ku86 |
| Q36706287 | Restoration of ATM Expression in DNA-PKcs-Deficient Cells Inhibits Signal End Joining |
| Q34048809 | Role of poly(ADP-ribosyl)ation in DNA-PKcs- independent V(D)J recombination. |
| Q37246230 | Roles for NBS1 in alternative nonhomologous end-joining of V(D)J recombination intermediates. |
| Q35005088 | Sensing of intermediates in V(D)J recombination by ATM. |
| Q38320880 | Signal joint formation is inhibited in murine scid preB cells and fibroblasts in substrates with homopolymeric coding ends. |
| Q41159581 | Specific Roles of XRCC4 Paralogs PAXX and XLF during V(D)J Recombination. |
| Q52109680 | The RAG-1/2 endonuclease causes genomic instability and controls CNS complications of lymphoblastic leukemia in p53/Prkdc-deficient mice. |
| Q38690281 | The Role of the Core Non-Homologous End Joining Factors in Carcinogenesis and Cancer |
| Q28115800 | The catalytic subunit of DNA-dependent protein kinase regulates proliferation, telomere length, and genomic stability in human somatic cells |
| Q35669767 | The catalytic subunit of DNA-protein kinase (DNA-PKcs) is not required for Ig class-switch recombination |
| Q35980970 | The life and death of DNA-PK. |
| Q33963869 | The p53 response to DNA damage in vivo is independent of DNA-dependent protein kinase |
| Q35159001 | Unique and redundant functions of ATM and DNA-PKcs during V(D)J recombination |
| Q35830443 | V(D)J recombination: how to tame a transposase |
| Q34170658 | V(D)J recombination: links to transposition and double-strand break repair. |
| Q34170672 | What prevents intermolecular V(D)J recombination? |
| Q24630098 | XRCC4's interaction with XLF is required for coding (but not signal) end joining |
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