Increased Dapivirine tissue accumulation through vaginal film codelivery of dapivirine and Tenofovir

scientific article

Increased Dapivirine tissue accumulation through vaginal film codelivery of dapivirine and Tenofovir is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1021/MP4007024
P932PMC publication ID4018102
P698PubMed publication ID24693866
P5875ResearchGate publication ID261325386

P2093author name stringAyman Akil
Brid Devlin
Lisa Cencia Rohan
Marilyn Cost
P2860cites workMicrobicides: topical prevention against HIVQ26999403
An antiretroviral/zinc combination gel provides 24 hours of complete protection against vaginal SHIV infection in macaquesQ27438093
Reverse transcriptase inhibitors as microbicidesQ30412039
Formulation, pharmacokinetics and pharmacodynamics of topical microbicidesQ30412592
A vaginal fluid simulantQ33653706
Combination of candidate microbicides cellulose acetate 1,2-benzenedicarboxylate and UC781 has synergistic and complementary effects against human immunodeficiency virus type 1 infectionQ33770052
Dawn of non-nucleoside inhibitor-based anti-HIV microbicidesQ34487295
In vitro evaluation of nonnucleoside reverse transcriptase inhibitors UC-781 and TMC120-R147681 as human immunodeficiency virus microbicidesQ35006752
In vitro resistance profile of the candidate HIV-1 microbicide drug dapivirineQ35689311
Development and Characterization of a Vaginal Film Containing Dapivirine, a Non- nucleoside Reverse Transcriptase Inhibitor (NNRTI), for prevention of HIV-1 sexual transmissionQ36033871
Safety and efficacy of tenofovir/IQP-0528 combination gels - a dual compartment microbicide for HIV-1 preventionQ36409617
Inhibition of human immunodeficiency virus type 1 infection by the candidate microbicide dapivirine, a nonnucleoside reverse transcriptase inhibitorQ37072072
Topical microbicides to prevent HIV: clinical drug development challengesQ37324508
Complete protection from repeated vaginal simian-human immunodeficiency virus exposures in macaques by a topical gel containing tenofovir alone or with emtricitabineQ37365377
Microbicide delivery: formulation technologies and strategies.Q37447846
The future of HIV microbicides: challenges and opportunities.Q37448790
Specific microbicides in the prevention of HIV infectionQ37932048
Future strategies in microbicide developmentQ37992384
In vitro and ex vivo evaluation of polymeric nanoparticles for vaginal and rectal delivery of the anti-HIV drug dapivirineQ39143650
Synergistic inhibition of HIV-1 infection by combinations of soluble polyanions with other potential microbicidesQ40149698
Synergy against drug-resistant HIV-1 with the microbicide antiretrovirals, dapivirine and tenofovir, in combinationQ42733122
Pharmacokinetics of 2 dapivirine vaginal microbicide gels and their safety vs. Hydroxyethyl cellulose-based universal placebo gel.Q43007169
Segmented polyurethane intravaginal rings for the sustained combined delivery of antiretroviral agents dapivirine and tenofovirQ43230603
A silicone elastomer vaginal ring for HIV prevention containing two microbicides with different mechanisms of actionQ43611191
Safety, tolerability, and systemic absorption of dapivirine vaginal microbicide gel in healthy, HIV-negative womenQ43809456
Pharmacokinetic Assessment of Dapivirine Vaginal Microbicide Gel in Healthy, HIV-Negative WomenQ57847699
Safety and Availability of Dapivirine (TMC120) Delivered from an Intravaginal RingQ57847719
In vitro profiling of the vaginal permeation potential of anti-HIV microbicides and the influence of formulation excipientsQ59285485
Distribution of lymphocytes and adhesion molecules in human cervix and vaginaQ62638937
Carrageenan/MIV-150 (PC-815), a combination microbicideQ80149044
Mucosal safety of PHI-443 and stampidine as a combination microbicide to prevent genital transmission of HIV-1Q80324830
Design of tenofovir-UC781 combination microbicide vaginal gelsQ83498741
Safety and pharmacokinetics of dapivirine delivery from matrix and reservoir intravaginal rings to HIV-negative womenQ84273601
P433issue5
P407language of work or nameEnglishQ1860
P921main subjecttenofovirQ155954
P304page(s)1533-1541
P577publication date2014-04-14
P1433published inMolecular PharmaceuticsQ3011140
P1476titleIncreased Dapivirine tissue accumulation through vaginal film codelivery of dapivirine and Tenofovir
P478volume11