scholarly article | Q13442814 |
P50 | author | Wendy Keung | Q51434667 |
Deborah M Muoio | Q56285554 | ||
John R Ussher | Q91702545 | ||
P2093 | author name string | Olga R Ilkayeva | |
Liyan Zhang | |||
Natasha Fillmore | |||
Timothy R Koves | |||
Jun Mori | |||
Gary D Lopaschuk | |||
Cory S Wagg | |||
David G Lopaschuk | |||
Jagdip S Jaswal | |||
P2860 | cites work | Prolonged inhibition of muscle carnitine palmitoyltransferase-1 promotes intramyocellular lipid accumulation and insulin resistance in rats | Q43516811 |
Trimetazidine reduces endogenous free fatty acid oxidation and improves myocardial efficiency in obese humans | Q44200139 | ||
Beneficial effects of trimetazidine in ex vivo working ischemic hearts are due to a stimulation of glucose oxidation secondary to inhibition of long-chain 3-ketoacyl coenzyme a thiolase | Q44517385 | ||
Role of the atypical protein kinase Czeta in regulation of 5'-AMP-activated protein kinase in cardiac and skeletal muscle. | Q45922672 | ||
A potential link between muscle peroxisome proliferator- activated receptor-alpha signaling and obesity-related diabetes | Q46626385 | ||
Metabolic modulation with perhexiline in chronic heart failure: a randomized, controlled trial of short-term use of a novel treatment | Q46814911 | ||
CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK. | Q48588727 | ||
Effect of pressure development on oxygen consumption by isolated rat heart | Q72218889 | ||
Tumor necrosis factor alpha-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling | Q79400004 | ||
Stimulation of glucose oxidation protects against acute myocardial infarction and reperfusion injury | Q83713235 | ||
Inhibition of malonyl-CoA decarboxylase reduces the inflammatory response associated with insulin resistance | Q85208761 | ||
2012 ACCF/AHA focused update incorporated into the ACCF/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Associat | Q86690927 | ||
Trimetazidine for stable angina | Q24245946 | ||
Pyridine nucleotide regulation of cardiac intermediary metabolism | Q26822692 | ||
The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus | Q28190307 | ||
Mitochondrial dysfunction due to long-chain Acyl-CoA dehydrogenase deficiency causes hepatic steatosis and hepatic insulin resistance | Q28253498 | ||
The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase | Q28373346 | ||
Malonyl coenzyme a decarboxylase inhibition protects the ischemic heart by inhibiting fatty acid oxidation and stimulating glucose oxidation | Q28578053 | ||
Cellular mechanisms of insulin resistance | Q29619549 | ||
Metformin influences cardiomyocyte cell death by pathways that are dependent and independent of caspase-3. | Q33251776 | ||
Skeletal muscle metabolism is a major determinant of resting energy expenditure | Q34262816 | ||
Disordered lipid metabolism and the pathogenesis of insulin resistance | Q34370965 | ||
A randomized clinical trial of trimetazidine, a partial free fatty acid oxidation inhibitor, in patients with heart failure | Q34562883 | ||
Trimetazidine, a metabolic modulator, has cardiac and extracardiac benefits in idiopathic dilated cardiomyopathy | Q34819581 | ||
Mitochondrial dysfunction in patients with primary congenital insulin resistance | Q35015797 | ||
Metabolic remodeling of human skeletal myocytes by cocultured adipocytes depends on the lipolytic state of the system. | Q35063267 | ||
Lipid-induced mitochondrial stress and insulin action in muscle | Q35947486 | ||
Continuous fat oxidation in acetyl-CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity | Q36082167 | ||
Augmenting muscle diacylglycerol and triacylglycerol content by blocking fatty acid oxidation does not impede insulin sensitivity | Q36122773 | ||
Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance | Q37105295 | ||
The malonyl CoA axis as a potential target for treating ischaemic heart disease | Q37171491 | ||
Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control | Q37371666 | ||
Targeting fatty acid and carbohydrate oxidation--a novel therapeutic intervention in the ischemic and failing heart. | Q37831555 | ||
A ceramide-centric view of insulin resistance | Q38007631 | ||
Gipr is essential for adrenocortical steroidogenesis; however, corticosterone deficiency does not mediate the favorable metabolic phenotype of Gipr(-/-) mice | Q39783085 | ||
Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance | Q40028148 | ||
Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption | Q41119321 | ||
Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans | Q42247172 | ||
Inhibition of carnitine palmitoyltransferase-1 activity alleviates insulin resistance in diet-induced obese mice. | Q43240756 | ||
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | obesity | Q12174 |
preproinsulin | Q7240673 | ||
insulin resistance | Q1053470 | ||
P304 | page(s) | 487-496 | |
P577 | publication date | 2014-04-03 | |
P1433 | published in | Journal of Pharmacology and Experimental Therapeutics | Q1500272 |
P1476 | title | Treatment with the 3-ketoacyl-CoA thiolase inhibitor trimetazidine does not exacerbate whole-body insulin resistance in obese mice | |
P478 | volume | 349 |