| scholarly article | Q13442814 |
| P50 | author | Clay F. Semenkovich | Q42738655 |
| John O. Holloszy | Q121141421 | ||
| P2093 | author name string | Brian N Finck | |
| Daniel P Kelly | |||
| Carlos Bernal-Mizrachi | |||
| Nandakumar Sambandam | |||
| Trey Coleman | |||
| Dong Ho Han | |||
| Lori L LaRiviere | |||
| P433 | issue | 2 | |
| P921 | main subject | obesity | Q12174 |
| P304 | page(s) | 133-144 | |
| P577 | publication date | 2005-02-01 | |
| P1433 | published in | Cell Metabolism | Q1254684 |
| P1476 | title | A potential link between muscle peroxisome proliferator- activated receptor-alpha signaling and obesity-related diabetes | |
| P478 | volume | 1 |
| Q34078111 | A diurnal serum lipid integrates hepatic lipogenesis and peripheral fatty acid use. |
| Q33789323 | Abrogating monoacylglycerol acyltransferase activity in liver improves glucose tolerance and hepatic insulin signaling in obese mice |
| Q35131396 | Altered fetal skeletal muscle nutrient metabolism following an adverse in utero environment and the modulation of later life insulin sensitivity. |
| Q53684513 | An aPPARent Functional Consequence in Skeletal Muscle Physiology via Peroxisome Proliferator-Activated Receptors. |
| Q35682887 | Aryl hydrocarbon receptor deficiency enhances insulin sensitivity and reduces PPAR-α pathway activity in mice |
| Q45809494 | Blocking central galanin receptors attenuates insulin sensitivity in myocytes of diabetic trained rats |
| Q58449845 | Calcineurin Regulates Skeletal Muscle Metabolism via Coordinated Changes in Gene Expression |
| Q36824112 | Cardiac lipotoxicity: molecular pathways and therapeutic implications |
| Q45070271 | Chronic maternal infusion of full-length adiponectin in pregnant mice down-regulates placental amino acid transporter activity and expression and decreases fetal growth |
| Q34452078 | Circadian rhythms, Wnt/beta-catenin pathway and PPAR alpha/gamma profiles in diseases with primary or secondary cardiac dysfunction |
| Q36163897 | Co-activator binding protein PIMT mediates TNF-α induced insulin resistance in skeletal muscle via the transcriptional down-regulation of MEF2A and GLUT4. |
| Q38326934 | Complete failure of insulin-transmitted signaling, but not obesity-induced insulin resistance, impairs respiratory chain function in muscle |
| Q84794925 | Connecting the dots: obesity, fatty acids and cancer |
| Q64376745 | Conserved transcriptional activity and ligand responsiveness of avian PPARs: Potential role in regulating lipid metabolism in mirgratory birds |
| Q33917888 | Cross-species gene expression analysis identifies a novel set of genes implicated in human insulin sensitivity |
| Q42523283 | Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism |
| Q34617976 | Diminished hepatic gluconeogenesis via defects in tricarboxylic acid cycle flux in peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha)-deficient mice |
| Q35561976 | Dissociation of diabetes and obesity in mice lacking orphan nuclear receptor small heterodimer partner |
| Q41217584 | Dissociation of muscle insulin sensitivity from exercise endurance in mice by HDAC3 depletion |
| Q30353176 | Effects of PPARalpha on cardiac glucose metabolism: a transcriptional equivalent of the glucose-fatty acid cycle? |
| Q36976374 | Endogenous peroxisome proliferator-activated receptor-gamma augments fatty acid uptake in oxidative muscle |
| Q42677218 | Exercise and high-fat feeding remodel transcript-metabolite interactive networks in mouse skeletal muscle. |
| Q28591952 | Farnesoid X receptor is essential for normal glucose homeostasis |
| Q42130623 | Fatty acids regulate perilipin5 in muscle by activating PPARδ |
| Q33803438 | Full-length adiponectin attenuates insulin signaling and inhibits insulin-stimulated amino Acid transport in human primary trophoblast cells |
| Q59072667 | Genetic Dissection of the Physiological Role of Skeletal Muscle in Metabolic Syndrome |
| Q35623601 | Genetic manipulations of PPARs: effects on obesity and metabolic disease |
| Q37227782 | Genome-wide linkage and regional association study of obesity-related phenotypes: the GenSalt study |
| Q36640675 | Glucocorticoids produce whole body insulin resistance with changes in cardiac metabolism |
| Q37407233 | Glycogen synthase 2 is a novel target gene of peroxisome proliferator-activated receptors |
| Q34450240 | IL-4/STAT6 immune axis regulates peripheral nutrient metabolism and insulin sensitivity |
| Q38831372 | In Silico Modeling for the Prediction of Dose and Pathway-Related Adverse Effects in Humans From In Vitro Repeated-Dose Studies. |
| Q43240756 | Inhibition of carnitine palmitoyltransferase-1 activity alleviates insulin resistance in diet-induced obese mice. |
| Q37429232 | Insulin resistance and altered systemic glucose metabolism in mice lacking Nur77. |
| Q36078772 | Insulin resistance and metabolic derangements in obese mice are ameliorated by a novel peroxisome proliferator-activated receptor γ-sparing thiazolidinedione |
| Q26829463 | Insulin resistance protects the heart from fuel overload in dysregulated metabolic states |
| Q30359509 | Insulin-resistant heart exhibits a mitochondrial biogenic response driven by the peroxisome proliferator-activated receptor-alpha/PGC-1alpha gene regulatory pathway. |
| Q35569436 | Integrative and systemic approaches for evaluating PPARβ/δ (PPARD) function |
| Q39180889 | Interactions between PPAR Gamma and the Canonical Wnt/Beta-Catenin Pathway in Type 2 Diabetes and Colon Cancer. |
| Q35596985 | Intramuscular triacylglycerol and insulin resistance: guilty as charged or wrongly accused? |
| Q21245684 | Intramyocellular lipid kinetics and insulin resistance |
| Q36528453 | Intramyocellular lipids: maker vs. marker of insulin resistance |
| Q38461386 | Is PPARα intron 7 G/C polymorphism associated with muscle strength characteristics in nonathletic young men? |
| Q30424438 | Kruppel-like factor 15 regulates skeletal muscle lipid flux and exercise adaptation. |
| Q93264363 | Lack of muscle mTOR kinase activity causes early onset myopathy and compromises whole-body homeostasis |
| Q50705604 | Lactational exposure of phthalate impairs insulin signaling in the cardiac muscle of F1 female albino rats. |
| Q37684850 | Lipid Use and Misuse by the Heart. |
| Q35947486 | Lipid-induced mitochondrial stress and insulin action in muscle |
| Q35728497 | Lipin-1 phosphatidic phosphatase activity modulates phosphatidate levels to promote peroxisome proliferator-activated receptor γ (PPARγ) gene expression during adipogenesis |
| Q28473405 | Long-chain fatty acid combustion rate is associated with unique metabolite profiles in skeletal muscle mitochondria |
| Q47836593 | Long-term rates of mitochondrial protein synthesis are increased in mouse skeletal muscle with high-fat feeding regardless of insulin-sensitizing treatment |
| Q47720090 | Loss of perilipin 2 in cultured myotubes enhances lipolysis and redirects the metabolic energy balance from glucose oxidation towards fatty acid oxidation. |
| Q90685522 | Mechanisms of Insulin Action and Insulin Resistance |
| Q34737010 | Mechanisms of disease:Molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes |
| Q39395315 | Metabolic Reprogramming via PPARα Signaling in Cardiac Hypertrophy and Failure From Metabolomics to Epigenetics. |
| Q55363508 | Metabolic and Cardiac Adaptation to Chronic Pharmacologic Blockade of Facilitative Glucose Transport in Murine Dilated Cardiomyopathy and Myocardial Ischemia. |
| Q37400761 | Metabolomics applied to diabetes research: moving from information to knowledge |
| Q33916535 | Mice deficient in group VIB phospholipase A2 (iPLA2gamma) exhibit relative resistance to obesity and metabolic abnormalities induced by a Western diet |
| Q36901558 | MicroRNA-21 promotes fibrosis of the kidney by silencing metabolic pathways |
| Q37294679 | Microarray analysis of gene expression in liver, adipose tissue and skeletal muscle in response to chronic dietary administration of NDGA to high-fructose fed dyslipidemic rats |
| Q37100064 | MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity. |
| Q42247172 | Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans |
| Q28487968 | Mitochondrial biogenesis drives a vicious cycle of metabolic insufficiency and mitochondrial DNA deletion mutation accumulation in aged rat skeletal muscle fibers |
| Q37210859 | Mitochondrial dysfunction in obesity |
| Q36865626 | Mitochondrial inhibitor as a new class of insulin sensitizer |
| Q33623344 | Mitochondrial response to nutrient availability and its role in metabolic disease. |
| Q38111713 | Molecular mechanisms of muscle plasticity with exercise |
| Q51379331 | Molecular therapy for obesity and diabetes based on a long-term increase in hepatic fatty-acid oxidation. |
| Q35429223 | Muscle as a "mediator" of systemic metabolism |
| Q37594450 | Muscle insulin sensitivity and glucose metabolism are controlled by the intrinsic muscle clock |
| Q30536570 | Muscle lipogenesis balances insulin sensitivity and strength through calcium signaling. |
| Q36891068 | Nuclear receptor/microRNA circuitry links muscle fiber type to energy metabolism |
| Q36151679 | Nuclear receptors PPARbeta/delta and PPARalpha direct distinct metabolic regulatory programs in the mouse heart |
| Q37692841 | Nuclear receptors and metabolism: from feast to famine |
| Q36585576 | Nuclear respiratory factor 1 controls myocyte enhancer factor 2A transcription to provide a mechanism for coordinate expression of respiratory chain subunits |
| Q35239136 | Nutrient sensing by the mitochondrial transcription machinery dictates oxidative phosphorylation |
| Q46972562 | Obesity Drug Update: The Lost Decade? |
| Q28088325 | Obesity, Oxidative Stress, Adipose Tissue Dysfunction, and the Associated Health Risks: Causes and Therapeutic Strategies |
| Q64098845 | Overexpression of Long-Chain Acyl-CoA Synthetase 5 Increases Fatty Acid Oxidation and Free Radical Formation While Attenuating Insulin Signaling in Primary Human Skeletal Myotubes |
| Q37105295 | Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance |
| Q39991764 | Oxidation of Intracellular and Extracellular Fatty Acids in Skeletal Muscle: Application of kinetic modeling, stable isotopes and liquid chromatography/electrospray ionization ion-trap tandem mass spectrometry technology |
| Q34230877 | PGC-1alpha coactivates PDK4 gene expression via the orphan nuclear receptor ERRalpha: a mechanism for transcriptional control of muscle glucose metabolism |
| Q37238001 | PPAR transcriptional activator complex polymorphisms and the promise of individualized therapy for heart failure |
| Q36959065 | PPARdelta Agonism for the Treatment of Obesity and Associated Disorders: Challenges and Opportunities |
| Q38285171 | PPARs and ERRs: molecular mediators of mitochondrial metabolism |
| Q92128876 | PPARs as Nuclear Receptors for Nutrient and Energy Metabolism |
| Q35606063 | PPARs in the Control of Uncoupling Proteins Gene Expression |
| Q37681306 | PPARs: diverse regulators in energy metabolism and metabolic diseases |
| Q33832975 | PPARα-independent actions of omega-3 PUFAs contribute to their beneficial effects on adiposity and glucose homeostasis |
| Q35970084 | Peroxisome proliferator-activated receptor γ decouples fatty acid uptake from lipid inhibition of insulin signaling in skeletal muscle |
| Q38308272 | Protection against Western diet-induced obesity and hepatic steatosis in liver fatty acid-binding protein knockout mice |
| Q36763111 | RXR: from partnership to leadership in metabolic regulations |
| Q35973475 | Raising plasma fatty acid concentration induces increased biogenesis of mitochondria in skeletal muscle. |
| Q38116348 | Redox regulation of insulin sensitivity due to enhanced fatty acid utilization in the mitochondria |
| Q38112060 | Regulation of mitochondrial biogenesis and GLUT4 expression by exercise |
| Q26825855 | Road to exercise mimetics: targeting nuclear receptors in skeletal muscle |
| Q41876713 | Role of Jhdm2a in regulating metabolic gene expression and obesity resistance |
| Q33751474 | Role of Nuclear Receptors in Exercise-Induced Muscle Adaptations. |
| Q38956714 | Sarcolipin: A Key Thermogenic and Metabolic Regulator in Skeletal Muscle |
| Q47604437 | Sex-dependent impact of Scp-2/Scp-x gene ablation on hepatic phytol metabolism |
| Q97643860 | Short-chain fatty acids as potential regulators of skeletal muscle metabolism and function |
| Q37193340 | Sirt3 regulates metabolic flexibility of skeletal muscle through reversible enzymatic deacetylation |
| Q90947313 | Skeletal muscle mitochondrial remodeling in exercise and diseases |
| Q24541529 | Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasis |
| Q55278796 | Sphingolipid regulators of cellular dysfunction in Type 2 diabetes mellitus: a systems overview. |
| Q93072634 | The HDAC3 enzymatic activity regulates skeletal muscle fuel metabolism |
| Q36326205 | The PPAR genes, cardiovascular disease and the emergence of PPAR pharmacogenetics |
| Q37337283 | The Randle cycle revisited: a new head for an old hat. |
| Q34106233 | The Role of PPARα Activation in Liver and Muscle |
| Q38734617 | The beneficial metabolic effects of insulin sensitizers are not attenuated by mitochondrial pyruvate carrier 2 hypomorphism. |
| Q64073403 | The class 3 PI3K coordinates autophagy and mitochondrial lipid catabolism by controlling nuclear receptor PPARα |
| Q28587753 | The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice |
| Q34567973 | The human obesity gene map: the 2005 update |
| Q38062033 | The impact of current and novel anti-diabetic therapies on cardiovascular risk |
| Q35642066 | The nuclear receptor PPARβ/δ programs muscle glucose metabolism in cooperation with AMPK and MEF2 |
| Q33779662 | The role of mitochondria in the pathophysiology of skeletal muscle insulin resistance |
| Q33942082 | The role of oxidative stress in the pathogenesis of type 2 diabetes: from molecular mechanism to clinical implication. |
| Q54610576 | Time-dependent effects of Prkce deletion on glucose homeostasis and hepatic lipid metabolism on dietary lipid oversupply in mice. |
| Q38385739 | Transcriptional regulatory circuits controlling muscle fiber type switching. |
| Q33603593 | Treatment with the 3-ketoacyl-CoA thiolase inhibitor trimetazidine does not exacerbate whole-body insulin resistance in obese mice |
| Q46231600 | Western diet impairs metabolic remodelling and contractile efficiency in cardiac hypertrophy |
| Q42774480 | Zinc finger protein 407 overexpression upregulates PPAR target gene expression and improves glucose homeostasis in mice. |
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