Protection against Western diet-induced obesity and hepatic steatosis in liver fatty acid-binding protein knockout mice

scientific article

Protection against Western diet-induced obesity and hepatic steatosis in liver fatty acid-binding protein knockout mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/HEP.21369
P698PubMed publication ID17058218
P5875ResearchGate publication ID6738227

P2093author name stringYan Xie
Jianyang Luo
Nicholas O Davidson
Susan M Kennedy
Elizabeth P Newberry
P2860cites workEffect of branched-chain fatty acid on lipid dynamics in mice lacking liver fatty acid binding protein geneQ45251473
Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding proteinQ45293298
A new transgenic rat model of hepatic steatosis and the metabolic syndromeQ46421393
A potential link between muscle peroxisome proliferator- activated receptor-alpha signaling and obesity-related diabetesQ46626385
Partial gene deletion of heart-type fatty acid-binding protein limits the severity of dietary-induced insulin resistanceQ46774694
Free fatty acids produce insulin resistance and activate the proinflammatory nuclear factor-kappaB pathway in rat liverQ46818626
Compensatory increase in hepatic lipogenesis in mice with conditional intestine-specific Mttp deficiency.Q46851248
Adaptations to the loss of intestinal fatty acid binding protein in miceQ46987404
Ablation of the Liver Fatty Acid Binding Protein Gene Decreases Fatty Acyl CoA Binding Capacity and Alters Fatty Acyl CoA Pool Distribution in Mouse LiverQ47597742
The intestinal fatty acid binding protein is not essential for dietary fat absorption in mice.Q52541214
Altered insulin secretion associated with reduced lipolytic efficiency in aP2-/- mice.Q54076811
Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascadeQ77795070
Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fastingQ24563197
Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistanceQ24629603
A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disordersQ28116120
Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target geneQ28138952
Decreased Hepatic Triglyceride Accumulation and Altered Fatty Acid Uptake in Mice with Deletion of the Liver Fatty Acid-binding Protein GeneQ28208142
Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetesQ28264518
The multigene family of fatty acid-binding proteins (FABPs): function, structure and polymorphismQ28292765
The binding of cholesterol and bile salts to recombinant rat liver fatty acid-binding proteinQ28301827
Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor alpha (PPARalpha)Q28509440
Adiponutrin, a transmembrane protein corresponding to a novel dietary- and obesity-linked mRNA specifically expressed in the adipose lineageQ28511072
Role of the fatty acid binding protein mal1 in obesity and insulin resistanceQ28587094
Metabolic syndrome without obesity: Hepatic overexpression of 11beta-hydroxysteroid dehydrogenase type 1 in transgenic miceQ33782682
Liver fatty acid binding protein gene ablation potentiates hepatic cholesterol accumulation in cholesterol-fed female miceQ34445819
Hepatic steatosis: a mediator of the metabolic syndrome. Lessons from animal modelsQ35625539
Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationshipsQ35883220
Biphasic expression of lipin suggests dual roles in adipocyte developmentQ36064786
The fatty liver and insulin resistanceQ36126652
Mind the gap: analysis of marker-assisted breeding strategies for inbred mouse strains.Q36441105
Differential effects of pharmacological liver X receptor activation on hepatic and peripheral insulin sensitivity in lean and ob/ob miceQ38325289
Liver fatty-acid-binding protein (L-FABP) gene ablation alters liver bile acid metabolism in male miceQ39499094
Variation of liver-type fatty acid binding protein content in the human hepatoma cell line HepG2 by peroxisome proliferators and antisense RNA affects the rate of fatty acid uptakeQ40969320
PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistanceQ43808960
Heterogeneous metabolic adaptation of C57BL/6J mice to high-fat dietQ43908141
Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated.Q43972538
Decreased liver fatty acid binding capacity and altered liver lipid distribution in mice lacking the liver fatty acid-binding protein geneQ44387480
Changes in adipokine expression during food deprivation in the mouse and the relationship to fasting-induced insulin resistanceQ44649369
Liver fatty acid binding protein is required for high rates of hepatic fatty acid oxidation but not for the action of PPARalpha in fasting miceQ44680979
The methionine-choline deficient dietary model of steatohepatitis does not exhibit insulin resistanceQ44691209
Liver fatty acid-binding protein gene ablation inhibits branched-chain fatty acid metabolism in cultured primary hepatocytesQ44904775
Heart fatty acid uptake is decreased in heart fatty acid-binding protein gene-ablated mice.Q44934606
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectobesityQ12174
fatty acidQ61476
knockout mouseQ1364740
steatosisQ1365091
P304page(s)1191-1205
P577publication date2006-11-01
P1433published inHepatologyQ15724398
P1476titleProtection against Western diet-induced obesity and hepatic steatosis in liver fatty acid-binding protein knockout mice
P478volume44

Reverse relations

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