review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Eric N Olson | |
Kedryn K Baskin | |||
Benjamin R Winders | |||
P2860 | cites work | An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis | Q24294691 |
Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha | Q24300512 | ||
Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex | Q24313231 | ||
MED1 phosphorylation promotes its association with mediator: implications for nuclear receptor signaling | Q24317446 | ||
PGC-1 coactivators: inducible regulators of energy metabolism in health and disease | Q24541524 | ||
Estrogen-related receptor alpha directs peroxisome proliferator-activated receptor alpha signaling in the transcriptional control of energy metabolism in cardiac and skeletal muscle | Q24561461 | ||
MiR-205 silences MED1 in hypoxic primary human trophoblasts | Q24608816 | ||
Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism | Q24650184 | ||
PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis | Q24798075 | ||
Regulation of muscle fiber type and running endurance by PPARdelta | Q24799428 | ||
Nuclear receptors and their selective pharmacologic modulators | Q26825692 | ||
Road to exercise mimetics: targeting nuclear receptors in skeletal muscle | Q26825855 | ||
Physiological functions of peroxisome proliferator-activated receptor β | Q26863667 | ||
Interleukin-6 myokine signaling in skeletal muscle: a double-edged sword? | Q26866208 | ||
Thyroid hormones and skeletal muscle--new insights and potential implications | Q26991631 | ||
The heart-liver metabolic axis: defective communication exacerbates disease | Q37710803 | ||
Metabolic crosstalk between the heart and liver impacts familial hypertrophic cardiomyopathy. | Q37710814 | ||
Diabetic Cardiomyopathy: Mechanisms and Therapeutic Targets | Q37832957 | ||
Myostatin: a novel insight into its role in metabolism, signal pathways, and expression regulation | Q37879255 | ||
Fiber types in mammalian skeletal muscles | Q37947567 | ||
Regulation of triglyceride metabolism by Angiopoietin-like proteins | Q37953715 | ||
The Mediator complex in thyroid hormone receptor action | Q37991879 | ||
The road to nuclear receptors of thyroid hormone | Q37997243 | ||
Thyroid hormone receptors: the challenge of elucidating isotype-specific functions and cell-specific response | Q38019236 | ||
The role of hepatokines in metabolism | Q38075770 | ||
Distinct functions for RIP140 in development, inflammation, and metabolism | Q38112486 | ||
The secretome of the working human skeletal muscle--a promising opportunity to combat the metabolic disaster? | Q38174593 | ||
The many roles of PGC-1α in muscle--recent developments | Q38190176 | ||
Epigenetic-induced repression of microRNA-205 is associated with MED1 activation and a poorer prognosis in localized prostate cancer | Q39301447 | ||
Cdk8 is essential for preimplantation mouse development | Q40109457 | ||
Metabolic regulation of epigenetics | Q41942880 | ||
Mediator phosphorylation prevents stress response transcription during non-stress conditions | Q42430988 | ||
Organ-tissue mass measurement allows modeling of REE and metabolically active tissue mass | Q42459142 | ||
Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay | Q42549325 | ||
Exercise and PGC-1α-independent synchronization of type I muscle metabolism and vasculature by ERRγ. | Q42723877 | ||
Selective activation of PPARgamma in skeletal muscle induces endogenous production of adiponectin and protects mice from diet-induced insulin resistance | Q43258047 | ||
IGF-1 overexpression inhibits the development of diabetic cardiomyopathy and angiotensin II-mediated oxidative stress | Q43618947 | ||
Metabolic gene expression in fetal and failing human heart | Q43819742 | ||
Peroxisome proliferator-activated receptor-alpha regulates fatty acid utilization in primary human skeletal muscle cells | Q43935379 | ||
Adaptation and maladaptation of the heart in diabetes: Part II: potential mechanisms | Q43961175 | ||
Cardiac glucose utilization in mice with mutated alpha- and beta-thyroid hormone receptors | Q45013711 | ||
Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults | Q45027927 | ||
Cardiomyocyte-restricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy | Q45099786 | ||
A potential link between muscle peroxisome proliferator- activated receptor-alpha signaling and obesity-related diabetes | Q46626385 | ||
Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle | Q47755014 | ||
ERRgamma directs and maintains the transition to oxidative metabolism in the postnatal heart. | Q51579173 | ||
Effects of thyroid hormone receptor gene disruption on myosin isoform expression in mouse skeletal muscles. | Q52167733 | ||
The nuclear receptor ERRalpha is required for the bioenergetic and functional adaptation to cardiac pressure overload. | Q55044173 | ||
PGC1α expression is controlled in skeletal muscles by PPARβ, whose ablation results in fiber-type switching, obesity, and type 2 diabetes | Q57848914 | ||
Skeletal muscle glycolytic and oxidative enzyme capacities are determinants of insulin sensitivity and muscle composition in obese women | Q61696377 | ||
Diabetic cardiomyopathy | Q68534926 | ||
Cardiac dysfunction caused by myocardium-specific expression of a mutant thyroid hormone receptor | Q73623176 | ||
Mediator-dependent nuclear receptor function | Q26995848 | ||
MicroRNAs as therapeutic targets and biomarkers of cardiovascular disease | Q27012405 | ||
Cardiokines: recent progress in elucidating the cardiac secretome | Q27022911 | ||
Metabolic benefits of resistance training and fast glycolytic skeletal muscle | Q27687459 | ||
Activation of PPARgamma coactivator-1 through transcription factor docking | Q28137806 | ||
Structure, function, and activator-induced conformations of the CRSP coactivator | Q28217949 | ||
Restoring systemic GDF11 levels reverses age-related dysfunction in mouse skeletal muscle | Q28239514 | ||
Regulation of lipogenesis by cyclin-dependent kinase 8-mediated control of SREBP-1 | Q28268591 | ||
The human Mediator complex: a versatile, genome-wide regulator of transcription | Q28276700 | ||
The Mediator complex and transcription regulation | Q28299679 | ||
The zebrafish kohtalo/trap230 gene is required for the development of the brain, neural crest, and pronephric kidney | Q28312198 | ||
The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus | Q28344691 | ||
A cardiac microRNA governs systemic energy homeostasis by regulation of MED13 | Q28505950 | ||
Deletion of PBP/PPARBP, the gene for nuclear receptor coactivator peroxisome proliferator-activated receptor-binding protein, results in embryonic lethality | Q28507387 | ||
Muscle-specific Pparg deletion causes insulin resistance | Q28508726 | ||
Transcription coactivator PBP, the peroxisome proliferator-activated receptor (PPAR)-binding protein, is required for PPARalpha-regulated gene expression in liver | Q28585245 | ||
Control of stress-dependent cardiac growth and gene expression by a microRNA | Q28587851 | ||
The TRAP100 component of the TRAP/Mediator complex is essential in broad transcriptional events and development | Q28592968 | ||
Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis | Q28594803 | ||
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes | Q29547229 | ||
Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres | Q29555845 | ||
Metabolic control through the PGC-1 family of transcription coactivators | Q29616509 | ||
Weight-reducing effects of the plasma protein encoded by the obese gene | Q29617934 | ||
Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome | Q29619211 | ||
From cytokine to myokine: the emerging role of interleukin-6 in metabolic regulation. | Q30361595 | ||
Complexity in transcription control at the activation domain-mediator interface | Q30491504 | ||
β-Aminoisobutyric acid induces browning of white fat and hepatic β-oxidation and is inversely correlated with cardiometabolic risk factors | Q33596037 | ||
MicroRNAs in metabolism and metabolic disorders | Q33612997 | ||
Minireview: Nuclear hormone receptor 4A signaling: implications for metabolic disease. | Q33637223 | ||
Thyroid hormone regulation of metabolism | Q33707954 | ||
Cyclin-dependent kinase 8 positively cooperates with Mediator to promote thyroid hormone receptor-dependent transcriptional activation | Q33826498 | ||
Transcriptional coregulators: fine-tuning metabolism | Q33838571 | ||
Heart- and muscle-derived signaling system dependent on MED13 and Wingless controls obesity in Drosophila | Q33854201 | ||
Mediator and human disease | Q33909044 | ||
A muscle-specific knockout implicates nuclear receptor coactivator MED1 in the regulation of glucose and energy metabolism | Q33933156 | ||
Nuclear receptor/microRNA circuitry links muscle fiber type to energy metabolism | Q36891068 | ||
The Mediator Complex and Lipid Metabolism | Q36938987 | ||
The PPAR trio: regulators of myocardial energy metabolism in health and disease | Q37156948 | ||
Transcriptional control of energy homeostasis by the estrogen-related receptors | Q37229563 | ||
ERRalpha: a metabolic function for the oldest orphan | Q37263563 | ||
A gender-related defect in lipid metabolism and glucose homeostasis in peroxisome proliferator- activated receptor alpha- deficient mice. | Q37387371 | ||
PPARγ signaling and metabolism: the good, the bad and the future | Q37407887 | ||
Insulin resistance and altered systemic glucose metabolism in mice lacking Nur77. | Q37429232 | ||
Cardiac metabolism in heart failure: implications beyond ATP production. | Q37495811 | ||
Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis | Q37526796 | ||
Estrogen-related receptor-α (ERRα) deficiency in skeletal muscle impairs regeneration in response to injury | Q37594018 | ||
Myocardial fatty acid metabolism in health and disease | Q37677921 | ||
Modulation of transcription factor function by O-GlcNAc modification | Q37702525 | ||
A mediator required for activation of RNA polymerase II transcription in vitro | Q34095554 | ||
Unraveling framework of the ancestral Mediator complex in human diseases | Q34222553 | ||
Muscles, exercise and obesity: skeletal muscle as a secretory organ | Q34265667 | ||
Liver Med23 ablation improves glucose and lipid metabolism through modulating FOXO1 activity. | Q34289895 | ||
Exercise metabolism and the molecular regulation of skeletal muscle adaptation | Q34326964 | ||
Mediator complex dependent regulation of cardiac development and disease | Q34348002 | ||
Large-scale identification of microRNA targets in murine Dgcr8-deficient embryonic stem cell lines | Q34388645 | ||
Involvement of Mediator complex in malignancy. | Q34392169 | ||
The roles of mediator complex in cardiovascular diseases | Q34416269 | ||
MicroRNA-1 functions as a potential tumor suppressor in osteosarcoma by targeting Med1 and Med31. | Q34426695 | ||
Cellular energy utilization and molecular origin of standard metabolic rate in mammals | Q34433543 | ||
Acetylation and nuclear receptor action | Q34666075 | ||
Regulation of peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1 alpha ) and mitochondrial function by MEF2 and HDAC5 | Q34761571 | ||
Adipokines as novel biomarkers and regulators of the metabolic syndrome | Q34786187 | ||
The cardiokine story unfolds: ischemic stress-induced protein secretion in the heart | Q34809985 | ||
MED13-dependent signaling from the heart confers leanness by enhancing metabolism in adipose tissue and liver | Q34881000 | ||
Exercise for the management of type 2 diabetes: a review of the evidence | Q34984837 | ||
Hepatic TRAP80 selectively regulates lipogenic activity of liver X receptor | Q35242621 | ||
Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones | Q35242884 | ||
MicroRNA 146 (Mir146) modulates spermatogonial differentiation by retinoic acid in mice | Q35617113 | ||
Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet | Q35621184 | ||
Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes | Q35780260 | ||
The metabolic role of IL-6 produced during exercise: is IL-6 an exercise factor? | Q35855943 | ||
Nuclear receptor signaling and cardiac energetics | Q35890852 | ||
Cardiomyocyte expression of PPARgamma leads to cardiac dysfunction in mice | Q35970883 | ||
Thyroid hormone action in the heart | Q35999776 | ||
Nuclear receptors PPARbeta/delta and PPARalpha direct distinct metabolic regulatory programs in the mouse heart | Q36151679 | ||
Fibroblast growth factor 21 is induced upon cardiac stress and alters cardiac lipid homeostasis | Q36196772 | ||
Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization | Q36387279 | ||
Signaling pathways in skeletal muscle remodeling | Q36498310 | ||
Effects of aerobic and/or resistance training on body mass and fat mass in overweight or obese adults | Q36530937 | ||
The SCF-Fbw7 ubiquitin ligase degrades MED13 and MED13L and regulates CDK8 module association with Mediator | Q36592394 | ||
Emerging roles of the corepressors NCoR1 and SMRT in homeostasis | Q36832163 | ||
Cardioselective dominant-negative thyroid hormone receptor (Delta337T) modulates myocardial metabolism and contractile efficiency | Q36846119 | ||
P433 | issue | 2 | |
P304 | page(s) | 237-248 | |
P577 | publication date | 2015-02-01 | |
P1433 | published in | Cell Metabolism | Q1254684 |
P1476 | title | Muscle as a "mediator" of systemic metabolism | |
P478 | volume | 21 |
Q92542875 | Adult Muscle Stem Cells: Exploring the Links Between Systemic and Cellular Metabolism |
Q33773474 | Age-Associated Loss of OPA1 in Muscle Impacts Muscle Mass, Metabolic Homeostasis, Systemic Inflammation, and Epithelial Senescence. |
Q58690883 | Analysis of the PPARD gene expression level changes in football players in response to the training cycle |
Q98566237 | Beneficial effects of running and milk protein supplements on Sirtuins and risk factors of metabolic disorders in rats with low aerobic capacity |
Q36701865 | Bone and Muscle Endocrine Functions: Unexpected Paradigms of Inter-organ Communication |
Q38979959 | Cardiac Med1 deletion promotes early lethality, cardiac remodeling, and transcriptional reprogramming. |
Q36248883 | E2F6 Impairs Glycolysis and Activates BDH1 Expression Prior to Dilated Cardiomyopathy |
Q64936166 | Effects of Exercise to Improve Cardiovascular Health. |
Q38907710 | Exploring inter-organ crosstalk to uncover mechanisms that regulate β-cell function and mass |
Q48222795 | Fibroblast growth factor 19 regulates skeletal muscle mass and ameliorates muscle wasting in mice |
Q92518448 | Fibroblast growth factor 21 controls mitophagy and muscle mass |
Q99637145 | Functional skeletal muscle model derived from SOD1-mutant ALS patient iPSCs recapitulates hallmarks of disease progression |
Q37014362 | Glycolytic-to-oxidative fiber-type switch and mTOR signaling activation are early-onset features of SBMA muscle modified by high-fat diet |
Q55369340 | Interventions Targeting Glucocorticoid-Krüppel-like Factor 15-Branched-Chain Amino Acid Signaling Improve Disease Phenotypes in Spinal Muscular Atrophy Mice. |
Q38669070 | Intramuscular Anabolic Signaling and Endocrine Response Following Resistance Exercise: Implications for Muscle Hypertrophy |
Q99248262 | KAP1-associated transcriptional inhibitory complex regulates C2C12 myoblasts differentiation and mitochondrial biogenesis via miR-133a repression |
Q58707682 | Lack of cyclin D3 induces skeletal muscle fiber-type shifting, increased endurance performance and hypermetabolism |
Q39085780 | Metabolism and Skeletal Muscle Homeostasis in Lung Disease. |
Q49642929 | MicroRNA-95 promotes myogenic differentiation by down-regulation of aminoacyl-tRNA synthase complex-interacting multifunctional protein 2. |
Q51043951 | Molecular bases of the crosstalk between bone and muscle. |
Q38697788 | Muscle Directs Diurnal Energy Homeostasis through a Myokine-Dependent Hormone Module in Drosophila |
Q36788620 | Nutrient sensing and utilization: Getting to the heart of metabolic flexibility |
Q37012238 | Osteocalcin Signaling in Myofibers Is Necessary and Sufficient for Optimum Adaptation to Exercise |
Q30837213 | Palmdelphin promotes myoblast differentiation and muscle regeneration |
Q87868370 | Prolonged high force high repetition pulling induces osteocyte apoptosis and trabecular bone loss in distal radius, while low force high repetition pulling induces bone anabolism |
Q39238946 | Reprogramming Interferon Regulatory Factor Signaling in Cardiometabolic Diseases |
Q41873853 | Role of microRNAs in obesity and obesity-related diseases |
Q48044643 | Sex-specific, reciprocal regulation of ERα and miR-22 controls muscle lipid metabolism in male mice |
Q91710658 | Skeletal Muscle Extracellular Matrix - What Do We Know About Its Composition, Regulation, and Physiological Roles? A Narrative Review |
Q52662687 | Skeletal muscle O-GlcNAc transferase is important for muscle energy homeostasis and whole-body insulin sensitivity. |
Q37351564 | Stage-specific effects of Notch activation during skeletal myogenesis. |
Q91984396 | Succinate induces skeletal muscle fiber remodeling via SUNCR1 signaling |
Q36901945 | The emerging role of skeletal muscle oxidative metabolism as a biological target and cellular regulator of cancer-induced muscle wasting |
Q91102316 | The relationships between sarcopenic skeletal muscle loss during ageing and macronutrient metabolism, obesity and onset of diabetes |
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