An in vitro system for studying murid herpesvirus-4 latency and reactivation

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An in vitro system for studying murid herpesvirus-4 latency and reactivation is …
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scholarly articleQ13442814

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P819ADS bibcode2010PLoSO...511080M
P356DOI10.1371/JOURNAL.PONE.0011080
P932PMC publication ID2884032
P698PubMed publication ID20552028
P5875ResearchGate publication ID44677002

P50authorPhilip G StevensonQ55743804
P2093author name stringJanet S May
Neil J Bennett
P2860cites workA gamma-herpesvirus immune evasion gene allows tumor cells in vivo to escape attack by cytotoxic T cells specific for a tumor epitopeQ62028503
Virological and pathological features of mice infected with murine gamma-herpesvirus 68Q67504691
Murine gammaherpesvirus 68 establishes a latent infection in mouse B lymphocytes in vivoQ67970625
Absence of splenic latency in murine gammaherpesvirus 68-infected B cell-deficient miceQ71786403
Changing patterns of dominance in the CD8+ T cell response during acute and persistent murine gamma-herpesvirus infectionQ77402434
Lytic cycle T cell epitopes are expressed in two distinct phases during MHV-68 infectionQ77967414
X-Linked agammaglobulinemia patients are not infected with Epstein-Barr virus: implications for the biology of the virusQ24517035
Gamma-herpesvirus latency requires T cell evasion during episome maintenanceQ24803420
IgG Fc Receptors Provide an Alternative Infection Route for Murine Gamma-Herpesvirus-68Q27480273
Reactivation of Epstein-Barr virus from latencyQ27728174
Epigenotypes of latent herpesvirus genomesQ28257829
Murine gammaherpesvirus-68 inhibits antigen presentation by dendritic cellsQ33302907
Endothelial cells support persistent gammaherpesvirus 68 infectionQ33369078
RTA promoter demethylation and histone acetylation regulation of murine gammaherpesvirus 68 reactivationQ33411313
Rta of murine gammaherpesvirus 68 reactivates the complete lytic cycle from latency.Q33802415
In vivo imaging of murid herpesvirus-4 infectionQ33910580
In vivo importance of heparan sulfate-binding glycoproteins for murid herpesvirus-4 infection.Q33910764
Gammaherpesvirus lytic gene expression as characterized by DNA arrayQ34339844
Latent membrane protein 1 inhibits Epstein-Barr virus lytic cycle induction and progress via different mechanisms.Q34532370
Kaposi sarcoma herpesvirus-induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma.Q34548882
Terminal differentiation into plasma cells initiates the replicative cycle of Epstein-Barr virus in vivoQ34553645
Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expressionQ34555693
Cloning and molecular characterization of the murine herpesvirus 68 genomeQ34631413
Disruption of gammaherpesvirus 68 gene 50 demonstrates that Rta is essential for virus replicationQ34977295
Viral interference with antigen presentationQ34983830
Activation of latent Kaposi's sarcoma-associated herpesvirus by demethylation of the promoter of the lytic transactivator.Q35056440
A secreted chemokine binding protein encoded by murine gammaherpesvirus-68 is necessary for the establishment of a normal latent loadQ36369458
Murine gammaherpesvirus M2 gene is latency-associated and its protein a target for CD8(+) T lymphocytes.Q36398571
Lung epithelial cells are a major site of murine gammaherpesvirus persistenceQ36401082
Lytic cycle switches of oncogenic human gammaherpesvirusesQ36786043
Establishment of B-cell lines latently infected with reactivation-competent murine gammaherpesvirus 68 provides evidence for viral alteration of a DNA damage-signaling cascadeQ36804603
Epigenetic regulation of Kaposi's sarcoma-associated herpesvirus replicationQ37476243
Measurement of ligand-induced activation in single viable T cells using the lacZ reporter geneQ37505330
Immune control of mammalian gamma-herpesviruses: lessons from murid herpesvirus-4.Q37552360
Murine gammaherpesvirus 68 lacking gp150 shows defective virion release but establishes normal latency in vivo.Q37730255
Non-antigen-specific B-cell activation following murine gammaherpesvirus infection is CD4 independent in vitro but CD4 dependent in vivo.Q39549238
Cloning and mutagenesis of the murine gammaherpesvirus 68 genome as an infectious bacterial artificial chromosomeQ39592358
The de novo methyltransferases DNMT3a and DNMT3b target the murine gammaherpesvirus immediate-early gene 50 promoter during establishment of latencyQ39732626
Characterization of tumor cell lines derived from murine gammaherpesvirus-68-infected mice.Q39876309
Lack of heparan sulfate expression in B-cell lines: implications for Kaposi's sarcoma-associated herpesvirus and murine gammaherpesvirus 68 infectionsQ39931204
Detection of circular and linear herpesvirus DNA molecules in mammalian cells by gel electrophoresis.Q40139467
Murine gammaherpesvirus-68 glycoprotein H-glycoprotein L complex is a major target for neutralizing monoclonal antibodies.Q40280948
An internal ribosome entry site directs translation of the murine gammaherpesvirus 68 MK3 open reading frame.Q40344541
Inefficient establishment of KSHV latency suggests an additional role for continued lytic replication in Kaposi sarcoma pathogenesis.Q40364647
Reversal of the silencing of tetracycline-controlled genes requires the coordinate action of distinctly acting transcription factorsQ40500931
Viral degradation of the MHC class I peptide loading complexQ40576858
Forced lytic replication impairs host colonization by a latency-deficient mutant of murine gammaherpesvirus-68.Q40600121
Virus subversion of the MHC class I peptide-loading complexQ40677035
MHC class I ubiquitination by a viral PHD/LAP finger protein.Q40773241
Kinetic and phenotypic changes in murine lymphocytes infected with murine gammaherpesvirus-68 in vitroQ40916130
An improved method for generating retroviral producer clones for vectors lacking a selectable marker geneQ41030731
Murine gamma-herpesvirus 68 causes severe large-vessel arteritis in mice lacking interferon-gamma responsiveness: a new model for virus-induced vascular disease.Q41077197
Interactions of murine gammaherpesvirus 68 with B and T cell linesQ41562310
K3-mediated evasion of CD8(+) T cells aids amplification of a latent gamma-herpesvirus.Q42812963
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)e11080
P577publication date2010-06-11
P1433published inPLOS OneQ564954
P1476titleAn in vitro system for studying murid herpesvirus-4 latency and reactivation
P478volume5

Reverse relations

cites work (P2860)
Q39329769CTCF and Sp1 interact with the Murine gammaherpesvirus 68 internal repeat elements
Q47552272Gamma-herpesvirus colonization of the spleen requires lytic replication in B cells.
Q37237637Suppression of TLR9 immunostimulatory motifs in the genome of a gammaherpesvirus

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