Polymorphisms of xenobiotic-metabolizing enzymes and susceptibility to cancer

scientific article

Polymorphisms of xenobiotic-metabolizing enzymes and susceptibility to cancer is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1289/EHP.99107S137
P932PMC publication ID1566364
P698PubMed publication ID10229705
P5875ResearchGate publication ID13068284

P2093author name stringHirvonen A
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SHORT COMMUNICATION: Glutathione S-transferase GSTT1 genotypes and susceptibility to cancer: studies of interactions with GSTM1 in lung, oral, gastric and colorectal cancersQ59904479
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Identification of an NAD(P)H:quinone oxidoreductase polymorphism and its association with lung cancer and smoking.Q41315418
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Polymorphism of glutathione S-transferase M1 and lung cancer risk among African-Americans and Caucasians in Los Angeles County, California.Q46049355
Frequencies of the defective CYP2C19 alleles responsible for the mephenytoin poor metabolizer phenotype in various Oriental, Caucasian, Saudi Arabian and American black populationsQ46141212
Ethnic distribution of slow acetylator mutations in the polymorphic N-acetyltransferase (NAT2) geneQ46569661
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Meta-analysis of studies of the CYP2D6 polymorphism in relation to lung cancer and Parkinson's disease.Q47773962
Nicotine metabolism defect reduces smokingQ47877657
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Interindividual variability of coumarin 7-hydroxylation in healthy volunteersQ67837226
Dissociation of a new glutathione S-transferase activity in human erythrocytesQ68109837
Monomorphic and polymorphic human arylamine N-acetyltransferases: a comparison of liver isozymes and expressed products of two cloned genesQ68199764
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Myeloperoxidase in human lung lavage. II. Internalization of myeloperoxidase by alveolar macrophagesQ68470987
DT-diaphorase: purification, properties, and functionQ68592259
Activation of promutagens by human cDNA-expressed cytochrome P450sQ68899927
Structural heterogeneity of Caucasian N-acetyltransferase at the NAT1 gene locusQ70583957
Lung cancer and mutations at the polymorphic NAT2 gene locusQ70803405
Glutathione S-transferase M1 (GSTM1) deficiency and lung cancer riskQ70863843
Human N-acetylation of benzidine: role of NAT1 and NAT2Q71381876
Both cytochromes P450 2E1 and 1A1 are involved in the metabolism of chlorzoxazoneQ71612339
Cigarette smoking, N-acetyltransferase 2 genetic polymorphisms, and breast cancer riskQ71748553
Occupational history and genetic N-acetyltransferase polymorphism in urothelial cancer patients of Leverkusen, GermanyQ71788233
Metabolic polymorphism affecting DNA binding and excretion of carcinogens in humansQ71794121
Polymorphism in the N-acetyltransferase 1 (NAT1) polyadenylation signal: association of NAT1*10 allele with higher N-acetylation activity in bladder and colon tissueQ71804979
Microsomal epoxide hydrolase polymorphism as a risk factor for ovarian cancerQ71835266
Inherited GSTM1 and NAT2 defects as concurrent risk modifiers in asbestos-related human malignant mesotheliomaQ71862667
Glutathione S-transferase and N-acetyltransferase genotypes and asbestos-associated pulmonary disordersQ71878642
Pulmonary expression of glutathione S-transferase M3 in lung cancer patients: association with GSTM1 polymorphism, smoking, and asbestos exposureQ71887283
Ultrarapid hydroxylation of debrisoquine in a Swedish population. Analysis of the molecular genetic basisQ71895813
Metabolic activation of the potent carcinogen dibenzo[a,l]pyrene by human recombinant cytochromes P450, lung and liver microsomesQ71899977
Polyadenylation polymorphism in the acetyltransferase 1 gene (NAT1) increases risk of colorectal cancerQ71939367
Detection of a Point Mutation in NQ01 (DT-diaphorase) in a Patient With Colon CancerQ71943987
Impaired (S)-warfarin metabolism catalysed by the R144C allelic variant of CYP2C9Q71996232
Prevalence of CYP2D6 gene duplication and its repercussion on the oxidative phenotype in a white populationQ72113258
Relationship between in vivo acetylator phenotypes and cytosolic N-acetyltransferase and O-acetyltransferase activities in human uroepithelial cellsQ72268447
Studies on interindividual variations of CYP2E1 using chlorzoxazone as an in vivo probeQ72293614
Interindividual variability of chlorzoxazone 6-hydroxylation in men and women and its relationship to CYP2E1 genetic polymorphismsQ72313196
Restriction fragment length polymorphism of the human CYP2E1 (cytochrome P450IIE1) gene and susceptibility to lung cancer: possible relevance to low smoking exposureQ72691106
Relationship in healthy subjects between CYP2E1 genetic polymorphisms and the 6-hydroxylation of chlorzoxazone: a putative measure of CYP2E1 activityQ72703173
Polymorphic arylamine N-acetyltransferase (NAT2) genes in children with insulin-dependent diabetes mellitusQ72893989
In vitro kinetics of two human CYP1A1 variant enzymes suggested to be associated with interindividual differences in cancer susceptibilityQ73154991
Identification of genetic polymorphisms at the glutathione S-transferase Pi locus and association with susceptibility to bladder, testicular and prostate cancerQ73248663
Active site architecture of polymorphic forms of human glutathione S-transferase P1-1 accounts for their enantioselectivity and disparate activity in the glutathione conjugation of 7beta,8alpha-dihydroxy-9alpha,10alpha-ox y-7,8,9,10-tetrahydrobenzo(Q73450157
Human acetyltransferase polymorphismsQ73457777
Increased frequency of a null-allele for NAD(P)H: quinone oxidoreductase in patients with urological malignanciesQ73553696
CYP2E1 genetic polymorphisms and risk of nasopharyngeal carcinoma in TaiwanQ73635116
A restriction fragment length polymorphism assay that differentiates human N-acetyltransferase-1 (NAT1) allelesQ73876084
Myeloperoxidase genetic polymorphism and lung cancer riskQ73883807
Cigarette smoking, cytochrome P450 1A1 polymorphisms, and breast cancer risk in the Nurses' Health StudyQ74251138
Polymorphism of the Pi class glutathione S-transferase in normal populations and cancer patientsQ74340204
Human microsomal epoxide hydrolase: 5'-flanking region genetic polymorphismsQ74390398
P921main subjectcancerQ12078
genetic variationQ349856
neoplasmQ1216998
pharmaceutical preparationQ66089252
P1104number of pages11
P304page(s)37-47
P577publication date1999-02-01
P1433published inEnvironmental Health PerspectivesQ1345904
P1476titlePolymorphisms of xenobiotic-metabolizing enzymes and susceptibility to cancer
P478volume107 Suppl 1

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