Opinion of the Scientific Committee on a request from EFSA related to A Harmonised Approach for Risk Assessment of Substances Which are both Genotoxic and Carcinogenic

scientific article published in October 2005

Opinion of the Scientific Committee on a request from EFSA related to A Harmonised Approach for Risk Assessment of Substances Which are both Genotoxic and Carcinogenic is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.2903/J.EFSA.2005.282
P8608Fatcat IDrelease_ys5evjibpjhkzevslrlq2mvdea

P50authorEuropean Food Safety AuthorityQ516521
P2860cites workThe Hallmarks of CancerQ221226
Oxidative Decay of DNAQ22066181
Application of benzo(a)pyrene and coal tar tumor dose-response data to a modified benchmark dose method of guideline developmentQ24815801
Functional characterization of polymorphisms in DNA repair genes using cytogenetic challenge assaysQ24816878
Genetic instabilities in human cancersQ28131826
Polymorphisms in the DNA repair genes XRCC1 and ERCC2 and biomarkers of DNA damage in human blood mononuclear cellsQ28143014
Ranking possible carcinogenic hazardsQ39769822
Investigations into the concept of a threshold for topoisomerase inhibitor-induced clastogenicityQ42163613
Aphidicolin and bleomycin induced chromosome damage as biomarker of mutagen sensitivity: a twin studyQ42456548
Associations between common polymorphisms in TP53 and p21WAF1/Cip1 and phenotypic features of breast cancerQ43901544
Nutritional modulation of DNA repair in a human intervention studyQ44381261
Biomarkers of dietary intake of micronutrients modulate DNA adduct levels in healthy adultsQ44427335
Symposium overview: genetic polymorphisms in DNA repair and cancer riskQ46345562
Molecular and cellular mechanisms associated with pulse-carcinogenesis in the rat nerbous system by ethyinitrosourea: ethylation of nucleic acids and elimination rates of ethylated bases from the DNA of different tissuesQ48605731
T25: a simplified carcinogenic potency index: description of the system and study of correlations between carcinogenic potency and species/site specificity and mutagenicityQ50134105
Variation in DNA repair is a factor in cancer susceptibility: a paradigm for the promises and perils of individual and population risk estimation?Q50160917
Thresholds in chemical carcinogenesis.Q52321753
Comparison of the EU T25 single point estimate method with benchmark dose response modeling for estimating potency of carcinogens.Q52935961
Cyclin D1 gene polymorphism is associated with an increased risk of urinary bladder cancer.Q53391983
Rodent carcinogens: setting prioritiesQ53486868
Dose-response relationship and low dose extrapolation in chemical carcinogenesis.Q53505977
In reply: carcinogenic risk estimation.Q53522221
Calculation of carcinogenic potency from long-term animal carcinogenesis experiments.Q53553612
Cyclin D1 gene polymorphism and susceptibility to lung cancer in a Chinese population.Q54767981
Carcinogenicity categorization of chemicals-new aspects to be considered in a European perspective.Q30341724
A carcinogenic potency database of the standardized results of animal bioassaysQ30498518
Genome changes and gene expression in human solid tumorsQ30841588
The refinement of uncertainty/safety factors in risk assessment by the incorporation of data on toxicokinetic variability in humansQ30986105
A comprehensive approach for integration of toxicity and cancer risk assessmentsQ33537456
Polymorphisms of xenobiotic-metabolizing enzymes and susceptibility to cancerQ33608783
p53 mutation spectrum and load: the generation of hypotheses linking the exposure of endogenous or exogenous carcinogens to human cancerQ33750337
Concepts of threshold in mutagenesis and carcinogenesisQ33816067
Significance of multiple mutations in cancerQ33846180
Cancer risk and low-penetrance susceptibility genes in gene-environment interactionsQ33928276
Markers of DNA repair and susceptibility to cancer in humans: an epidemiologic reviewQ33936434
Biological indicators of genotoxic risk and metabolic polymorphismsQ34053171
The XPD variant alleles are associated with increased aromatic DNA adduct level and lung cancer riskQ34124392
Risk characterisation of chemicals in food and dietQ34218408
Hazard characterisation of chemicals in food and diet. dose response, mechanisms and extrapolation issuesQ34563180
Mathematical modelling and quantitative methodsQ34563187
Assessment of intake from the dietQ34563195
Gene-environment interaction and aetiology of cancer: what does it mean and how can we measure it?Q34564801
Molecular epidemiology in environmental health: the potential of tumor suppressor gene p53 as a biomarkerQ34639833
Chronological supplement to the Carcinogenic Potency Database: standardized results of animal bioassays published through December 1982.Q34659855
Second chronological supplement to the Carcinogenic Potency Database: standardized results of animal bioassays published through December 1984 and by the National Toxicology Program through May 1986.Q34660367
Sixth plot of the carcinogenic potency database: results of animal bioassays published in the General Literature 1989 to 1990 and by the National Toxicology Program 1990 to 1993.Q34834249
The fifth plot of the Carcinogenic Potency Database: results of animal bioassays published in the general literature through 1988 and by the National Toxicology Program through 1989.Q34843362
Summary of carcinogenic potency and positivity for 492 rodent carcinogens in the carcinogenic potency databaseQ35032800
Third chronological supplement to the carcinogenic potency database: standardized results of animal bioassays published through December 1986 and by the National Toxicology Program through June 1987.Q35032972
The Carcinogenic Potency Database: analyses of 4000 chronic animal cancer experiments published in the general literature and by the U.S. National Cancer Institute/National Toxicology ProgramQ35034775
Challenges and complexities in estimating both the functional impact and the disease risk associated with the extensive genetic variation in human DNA repair genesQ35114513
Genomic instability and cancer: networks involved in response to DNA damageQ36185744
O4-ethyldeoxythymidine, but not O6-ethyldeoxyguanosine, accumulates in hepatocyte DNA of rats exposed continuously to diethylnitrosamineQ36255316
Molecular themes in oncogenesisQ37625792
Cell proliferation in carcinogenesisQ37951208
XPD exon 10 and 23 polymorphisms and DNA repair in human skin in situQ38298525
Hormesis--the stimulation of growth by low levels of inhibitorsQ38579123
Inherited susceptibility to bleomycin-induced chromatid breaks in cultured peripheral blood lymphocytesQ39118556
Properties and assay of mammalian O6-alkylguanine-DNA alkyltransferaseQ39681347
P433issue10
P921main subjectgenotoxicityQ1009245
P304page(s)282
P577publication date2005-10-01
P1433published inEFSA JournalQ56298557
P1476titleOpinion of the Scientific Committee on a request from EFSA related to A Harmonised Approach for Risk Assessment of Substances Which are both Genotoxic and Carcinogenic
P478volume3