SMAD4--molecular gladiator of the TGF-beta signaling is trampled upon by mutational insufficiency in colorectal carcinoma of Kashmiri population: an analysis with relation to KRAS proto-oncogene.

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SMAD4--molecular gladiator of the TGF-beta signaling is trampled upon by mutational insufficiency in colorectal carcinoma of Kashmiri population: an analysis with relation to KRAS proto-oncogene. is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1000379561
P356DOI10.1186/1471-2407-10-300
P932PMC publication ID2927996
P698PubMed publication ID20565773
P5875ResearchGate publication ID44690283

P50authorSyed SameerQ82542222
Mujeeb Zafar BandayQ60312022
P2093author name stringMushtaq A Siddiqi
Zaffar A Shah
Nissar A Chowdri
Nidda Syeed
P2860cites workTGF-beta signal transductionQ22003891
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A study on p53 gene alterations in esophageal squamous cell carcinoma and their correlation to common dietary risk factors among population of the Kashmir valleyQ33867434
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Crosstalk mechanisms between the mitogen-activated protein kinase pathways and Smad signaling downstream of TGF-beta: implications for carcinogenesis.Q36241249
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Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancerQ39076225
Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathwaysQ40757186
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Increased exposure to dietary amines and nitrate in a population at high risk of oesophageal and gastric cancer in Kashmir (India).Q53488528
Loss of growth factor dependence and conversion of transforming growth factor-beta 1 inhibition to stimulation in metastatic H-ras-transformed murine fibroblasts.Q53518984
Aberrant promoter methylation and reduced expression of p16 gene in esophageal squamous cell carcinoma from Kashmir valley: a high-risk area.Q54478240
APC, K-ras, and p53 gene mutations in colorectal cancer patients: correlation to clinicopathologic features and postoperative surveillance.Q54484863
Role of Ras signaling in the induction of snail by transforming growth factor-beta.Q54788258
Epidemiology of colorectal cancerQ56994980
Heterogeneity of mutant versus wild-type Ki-ras in primary and metastatic colorectal carcinomas, and association of codon-12 valine with early mortalityQ57729160
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DPC4 gene in various tumor typesQ71129127
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Higher frequency of Smad4 gene mutation in human colorectal cancer with distant metastasisQ77787482
TGF-beta and cancerQ81484456
P407language of work or nameEnglishQ1860
P921main subjectcolorectal carcinomaQ25493920
P304page(s)300
P577publication date2010-06-17
P1433published inBMC CancerQ326300
P1476titleSMAD4--molecular gladiator of the TGF-beta signaling is trampled upon by mutational insufficiency in colorectal carcinoma of Kashmiri population: an analysis with relation to KRAS proto-oncogene
P478volume10

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cites work (P2860)
Q36477008Analysis of molecular aberrations of Wnt pathway gladiators in colorectal cancer in the Kashmiri population
Q38082475Colorectal cancer: a researcher's perspective of the molecular angel's gone eccentric in the Vale of Kashmir
Q38191462Genetic unraveling of colorectal cancer
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Q36475153Role of CYP2E1 genotypes in susceptibility to colorectal cancer in the Kashmiri population.
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Q101133262Signal transduction pathway mutations in gastrointestinal (GI) cancers: a systematic review and meta-analysis
Q36383337The blues of P(16)INK(4a): aberrant promoter methylation and association with colorectal cancer in the Kashmir valley.

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