Microdroplets in microfluidics: an evolving platform for discoveries in chemistry and biology

scientific article

Microdroplets in microfluidics: an evolving platform for discoveries in chemistry and biology is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1002/ANIE.200906653
P698PubMed publication ID20572214
P5875ResearchGate publication ID44696547

P50authorWilhelm T. S. HuckQ24517843
Yolanda SchaerliQ51562602
Florian HollfelderQ38804519
Martin FischlechnerQ54022412
P2093author name stringChris Abell
Ashleigh B Theberge
Fabienne Courtois
P2860cites workReactions in droplets in microfluidic channelsQ24675312
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Microdroplet-based PCR enrichment for large-scale targeted sequencingQ30481756
Control and measurement of the phase behavior of aqueous solutions using microfluidicsQ30483419
Controlled encapsulation of single-cells into monodisperse picolitre drops.Q30484168
The chemistrode: a droplet-based microfluidic device for stimulation and recording with high temporal, spatial, and chemical resolutionQ30484452
Sizing subcellular organelles and nanoparticles confined within aqueous dropletsQ30488035
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Controlling nonspecific protein adsorption in a plug-based microfluidic system by controlling interfacial chemistry using fluorous-phase surfactantsQ30502014
Nucleation and solidification in static arrays of monodisperse dropsQ30655250
Reliable microfluidic on-chip incubation of droplets in delay-linesQ30839260
Millisecond Kinetics on a Microfluidic Chip Using Nanoliters of ReagentsQ31026935
Continuous segmented-flow polymerase chain reaction for high-throughput miniaturized DNA amplificationQ31126046
Selective encapsulation of single cells and subcellular organelles into picoliter- and femtoliter-volume dropletsQ31153025
Selection of ribozymes that catalyse multiple-turnover Diels-Alder cycloadditions by using in vitro compartmentalizationQ33226328
High-throughput screening of enzyme libraries: in vitro evolution of a beta-galactosidase by fluorescence-activated sorting of double emulsions.Q33229577
Microgram-scale testing of reaction conditions in solution using nanoliter plugs in microfluidics with detection by MALDI-MS.Q33234439
On-chip electrocoalescence of microdroplets as a function of voltage, frequency and droplet sizeQ47174781
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Biocompatible surfactants for water-in-fluorocarbon emulsions.Q47330807
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Drop mixing in a microchannel for lab-on-a-chip platformsQ48033191
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Dripping to jetting transitions in coflowing liquid streams.Q50891397
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Coding/decoding and reversibility of droplet trains in microfluidic networks.Q51088670
Raman spectroscopic monitoring of droplet polymerization in a microfluidic device.Q51117302
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Electrically initiated upstream coalescence cascade of droplets in a microfluidic flow.Q51562541
Amplification of complex gene libraries by emulsion PCR.Q33247540
On-line laser Raman spectroscopic probing of droplets engineered in microfluidic devicesQ33255063
Capillary electrophoresis separation in the presence of an immiscible boundary for droplet analysisQ33258724
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Thermocapillary valve for droplet production and sortingQ33284555
An optical toolbox for total control of droplet microfluidicsQ33291772
Static microdroplet arrays: a microfluidic device for droplet trapping, incubation and release for enzymatic and cell-based assaysQ33410117
Manufacture of chitosan microbeads using centrifugally driven flow of gel-forming solutions through a polymeric micronozzle.Q33442389
Simultaneous measurement of reactions in microdroplets filled by concentration gradientsQ33460453
A fast and efficient microfluidic system for highly selective one-to-one droplet fusionQ33496455
Suzuki-Miyaura coupling reactions in aqueous microdroplets with catalytically active fluorous interfacesQ33510355
Compartmentalization of chemically separated components into dropletsQ33834861
Detection and quantification of mutations in the plasma of patients with colorectal tumorsQ34132363
A microfluidic system for controlling reaction networks in timeQ34178733
Dilution-free analysis from picoliter droplets by nano-electrospray ionization mass spectrometryQ34211779
Solvent compatibility of poly(dimethylsiloxane)-based microfluidic devicesQ34279256
Size control of calcium alginate beads containing living cells using micro-nozzle arrayQ34377170
BEAMing: single-molecule PCR on microparticles in water-in-oil emulsionsQ34540801
Gene transcript amplification from cell lysates in continuous-flow microfluidic devices.Q34626960
Analysis of samples stored as individual plugs in a capillary by electrospray ionization mass spectrometryQ34988946
Microfabricated devices: A new sample introduction approach to mass spectrometry.Q36410165
Measurement of activity of single molecules of beta-D-galactosidaseQ36442126
Microfluidics for multiplexed MS analysisQ36659046
Multiphase microfluidics: from flow characteristics to chemical and materials synthesisQ36699093
Effects of ultrasmall orifices on the electrogeneration of femtoliter-volume aqueous dropletsQ36851837
Thermoelectric manipulation of aqueous droplets in microfluidic devicesQ36857031
A decade of microfluidic analysis coupled with electrospray mass spectrometry: an overviewQ36981206
Defined spatial structure stabilizes a synthetic multispecies bacterial communityQ36984976
Droplet microfluidicsQ37071620
Plug-based microfluidics with defined surface chemistry to miniaturize and control aggregation of amyloidogenic peptidesQ37175261
Novel method for high-throughput colony PCR screening in nanoliter-reactorsQ37181584
Microdroplets: a sea of applications?Q37225409
Microfluidic chip-based synthesis of alginate microspheres for encapsulation of immortalized human cellsQ37260053
Laterally mobile, functionalized self-assembled monolayers at the fluorous-aqueous interface in a plug-based microfluidic system: characterization and testing with membrane protein crystallizationQ37340292
Microfluidic confinement of single cells of bacteria in small volumes initiates high-density behavior of quorum sensing and growth and reveals its variabilityQ37357755
Microfluidic crystallizationQ37390412
High-throughput quantitative polymerase chain reaction in picoliter dropletsQ37408877
On-chip, real-time, single-copy polymerase chain reaction in picoliter dropletsQ39816930
On-chip single-copy real-time reverse-transcription PCR in isolated picoliter dropletsQ39834835
Detection and analysis of low-abundance cell-surface biomarkers using enzymatic amplification in microfluidic dropletsQ39880732
Droplet-based microfluidic systems for high-throughput single DNA molecule isothermal amplification and analysisQ39888941
Micro fluid segment technique for screening and development studies on Danio rerio embryosQ40181294
Continuous microfluidic reactors for polymer particlesQ40369114
Droplets for ultrasmall-volume analysisQ41729086
Detecting bacteria and determining their susceptibility to antibiotics by stochastic confinement in nanoliter droplets using plug-based microfluidicsQ41846129
Sampling and electrophoretic analysis of segmented flow streams using virtual walls in a microfluidic deviceQ41874762
On-chip titration of an anticoagulant argatroban and determination of the clotting time within whole blood or plasma using a plug-based microfluidic systemQ42076867
Experimental test of scaling of mixing by chaotic advection in droplets moving through microfluidic channelsQ42579173
Microfluidic large-scale integrationQ44156086
Shear-driven redistribution of surfactant affects enzyme activity in well-mixed femtoliter droplets.Q44517980
Nonviral gene vector formation in monodispersed picolitre incubator for consistent gene deliveryQ44631611
The intensification of rapid reactions in multiphase systems using slug flow in capillariesQ44853819
Generic expansion of the substrate spectrum of a DNA polymerase by directed evolutionQ44905168
Fluorescence-activated droplet sorting (FADS): efficient microfluidic cell sorting based on enzymatic activity.Q45966490
Controlling the retention of small molecules in emulsion microdroplets for use in cell-based assaysQ46089235
Monodisperse droplet generation and rapid trapping for single molecule detection and reaction kinetics measurementQ46099019
The electrochemical detection of droplets in microfluidic devicesQ46304770
Droplet-based microfluidic system for individual Caenorhabditis elegans assayQ46345718
Monitoring of real-time streptavidin-biotin binding kinetics using droplet microfluidicsQ46422439
Mixing crowded biological solutions in millisecondsQ46435064
Continuous fabrication of biocatalyst immobilized microparticles using photopolymerization and immiscible liquids in microfluidic systemsQ46441926
Observed velocity fluctuations in monodisperse droplet generatorsQ46464672
Design of microfluidic channel geometries for the control of droplet volume, chemical concentration, and sortingQ46622256
High-throughput single copy DNA amplification and cell analysis in engineered nanoliter dropletsQ46646435
Microfluidic droplet-based liquid-liquid extractionQ46693064
From microdroplets to microfluidics: selective emulsion separation in microfluidic devicesQ46761240
Synthesis of monodisperse biodegradable microgels in microfluidic devicesQ46785151
On-chip manipulation of continuous picoliter-volume superparamagnetic droplets using a magnetic force.Q51563372
Formation of supramolecular hydrogel microspheres via microfluidics.Q51563393
Multi-step microfluidic droplet processing: kinetic analysis of an in vitro translated enzyme.Q51563417
Beating Poisson encapsulation statistics using close-packed ordering.Q51564117
Surface acoustic wave (SAW) directed droplet flow in microfluidics for PDMS devices.Q51564121
Spray performance of microfluidic glass devices with integrated pulled nanoelectrospray emitters.Q51564627
Synthesizing microcapsules with controlled geometrical and mechanical properties with microfluidic double emulsion technology.Q51564929
In situ formation, manipulation, and imaging of droplet-encapsulated fibrin networks.Q51565499
Measuring rapid enzymatic kinetics by electrochemical method in droplet-based microfluidic devices with pneumatic valves.Q51565609
Towards an integrated chemical circuit.Q51567435
Dropspots: a picoliter array in a microfluidic device.Q51568373
A microfluidic droplet generator based on a piezoelectric actuator.Q51568575
Nanostructured biosensing platform-shadow edge lithography for high-throughput nanofabrication.Q51568870
Simple, robust storage of drops and fluids in a microfluidic device.Q51569382
Pillar-induced droplet merging in microfluidic circuits.Q51570724
Chemical reaction imaging within microfluidic devices using confocal raman spectroscopy: the case of water and deuterium oxide as a model system.Q51575865
Microfluidic bubble logic.Q51581631
Microfluidic production of biopolymer microcapsules with controlled morphology.Q51583902
Droplet formation in a microchannel network.Q51597083
Generation of larger numbers of separated microbial populations by cultivation in segmented-flow microdevices.Q51597394
Dynamics of coalescence of plugs with a hydrophilic wetting layer induced by flow in a microfluidic chemistrode.Q51802546
Determination of dynamic interfacial tension and its effect on droplet formation in the T-shaped microdispersion process.Q51855973
Microfluidic production of droplet pairs.Q51868155
Fluorescence lifetime imaging of mixing dynamics in continuous-flow microdroplet reactors.Q51870328
Surface-enhanced Raman scattering in nanoliter droplets: towards high-sensitivity detection of mercury (II) ions.Q51956598
The origin of the "one cell-one antibody" rule.Q53117756
Analysis of protein-protein interactions by using droplet-based microfluidics.Q53506621
Contamination-free continuous flow microfluidic polymerase chain reaction for quantitative and clinical applications.Q54661600
Formation of Droplets and Mixing in Multiphase Microfluidics at Low Values of the Reynolds and the Capillary NumbersQ56533766
Thermally mediated droplet formation in microchannelsQ56746711
Quantitative detection of protein expression in single cells using droplet microfluidicsQ56814026
Microfluidic and optical systems for the on-demand generation and manipulation of single femtoliter-volume aqueous dropletsQ56893964
Micro Total Analysis Systems: Latest AchievementsQ57238454
Dynamic Pattern Formation in a Vesicle-Generating Microfluidic DeviceQ57258627
Microfluidic methods for generating continuous droplet streamsQ57258629
Formation of dispersions using “flow focusing” in microchannelsQ57258632
Microfluidic Assembly of Magnetic Hydrogel Particles with Uniformly Anisotropic StructureQ57340726
Microfluidic Synthesis of Reversibly Swelling Porous Polymeric Microcapsules with Controlled MorphologyQ57341533
The development of microgels/nanogels for drug delivery applicationsQ57356724
Stochastic protein expression in individual cells at the single molecule levelQ57534158
Janus and Ternary Particles Generated by Microfluidic Synthesis: Design, Synthesis, and Self-AssemblyQ57783279
Electro-Coalescence of Digitally Controlled DropletsQ57948224
Thermally mediated control of liquid microdroplets at a bifurcationQ58758309
Thermally controlled droplet formation in flow focusing geometry: formation regimes and effect of nanoparticle suspensionQ58758354
P433issue34
P407language of work or nameEnglishQ1860
P921main subjectmicrofluidicsQ138845
microdropletQ87446206
P304page(s)5846-5868
P577publication date2010-08-01
P1433published inAngewandte Chemie International EditionQ62023953
P1476titleMicrodroplets in microfluidics: an evolving platform for discoveries in chemistry and biology
P478volume49

Reverse relations

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Q34125975Locally enhanced concentration and detection of oligonucleotides in a plug-based microfluidic device
Q30357098Macromolecular interactions of the bacterial division FtsZ protein: from quantitative biochemistry and crowding to reconstructing minimal divisomes in the test tube
Q44999773Magnetofluidic platform for multidimensional magnetic and optical barcoding of droplets
Q51454792Measurement of the hydrodynamic resistance of microdroplets.
Q34540399Metabolic variability in micro-populations
Q36971572Micro-optical lens array for fluorescence detection in droplet-based microfluidics
Q47614991Micro-segmented flow and multisensor-technology for microbial activity profiling
Q48107761Microbubble transport through a bifurcating vessel network with pulsatile flow.
Q35280478Microdroplet fusion mass spectrometry for fast reaction kinetics
Q89170525Microfluidic Devices for Drug Assays
Q26741377Microfluidic Devices for Forensic DNA Analysis: A Review
Q91845456Microfluidic Study of the Electrocoalescence of Aqueous Droplets in Crude Oil
Q38031776Microfluidic designs and techniques using lab-on-a-chip devices for pathogen detection for point-of-care diagnostics
Q51490868Microfluidic droplet handling by bulk acoustic wave (BAW) acoustophoresis.
Q38126823Microfluidic electroporation for cellular analysis and delivery
Q27316870Microfluidic platform combining droplets and magnetic tweezers: application to HER2 expression in cancer diagnosis
Q34161599Microfluidic platform for combinatorial synthesis in picolitre droplets
Q40288897Microfluidic plug steering using surface acoustic waves.
Q50443466Microfluidic static droplet array for analyzing microbial communication on a population gradient.
Q38261503Microfluidic synthesis of barcode particles for multiplex assays
Q51529157Microfluidic traps for hard-wired operations on droplets.
Q92915513Microfluidic-Based Droplet and Cell Manipulations Using Artificial Bacterial Flagella
Q92343343Microfluidic-based observation of local bacterial density under antimicrobial concentration gradient for rapid antibiotic susceptibility testing
Q38192544Microfluidics for the analysis of membrane proteins: how do we get there?
Q38056670Microfluidics in the "open space" for performing localized chemistry on biological interfaces
Q51518407Micropillar arrays enabling single microbial cell encapsulation in hydrogels.
Q90402707Micropipette-powered droplet based microfluidics
Q51545155Millifluidic droplet analyser for microbiology.
Q37710863Millifluidics for chemical synthesis and time-resolved mechanistic studies
Q37981028Miniaturised technologies for the development of artificial lipid bilayer systems
Q47929572Mixed emulsion of liquid crystal microresonators: towards white laser systems
Q42122851Modulating patterns of two-phase flow with electric fields.
Q51469585Monitoring Early-Stage Nanoparticle Assembly in Microdroplets by Optical Spectroscopy and SERS.
Q90723646Monitoring phase transition of aqueous biomass model substrates by high-pressure and high-temperature microfluidics
Q36419901Monodisperse alginate microgel formation in a three-dimensional microfluidic droplet generator
Q64979146Monodisperse droplet formation by spontaneous and interaction based mechanisms in partitioned EDGE microfluidic device.
Q39541230Multiplex digital PCR: breaking the one target per color barrier of quantitative PCR.
Q34403699Nanoscale spatially resolved infrared spectra from single microdroplets
Q38238560Novel droplet platforms for the detection of disease biomarkers
Q92915434Numerical Investigation of Cell Encapsulation for Multiplexing Diagnostic Assays Using Novel Centrifugal Microfluidic Emulsification and Separation Platform
Q30504078Observation of spatial propagation of amyloid assembly from single nuclei
Q47327012Oil encapsulation techniques using alginate as encapsulating agent: applications and drawbacks
Q40898121Oil-isolated hydrogel microstructures for sensitive bioassays on-chip
Q36165484Oil-sealed femtoliter fiber-optic arrays for single molecule analysis
Q51511495On the flow topology inside droplets moving in rectangular microchannels.
Q51500843On-chip monitoring of chemical syntheses in microdroplets via surface-enhanced Raman spectroscopy.
Q51519793On-chip spyhole mass spectrometry for droplet-based microfluidics.
Q57367310On-chip thermo-triggered coalescence of controllable Pickering emulsion droplet pairs
Q51550841On-demand microfluidic droplet manipulation using hydrophobic ferrofluid as a continuous-phase.
Q35092096One in a million: flow cytometric sorting of single cell-lysate assays in monodisperse picolitre double emulsion droplets for directed evolution
Q92888266Operation of Droplet-Microfluidic Devices with a Lab Centrifuge
Q51501228Optofluidic ultrahigh-throughput detection of fluorescent drops.
Q38843524Oscillatory multiphase flow strategy for chemistry and biology
Q50988865Oscillatory three-phase flow reactor for studies of bi-phasic catalytic reactions.
Q51528168Parallel measurements of reaction kinetics using ultralow-volumes.
Q34382174Probing cellular heterogeneity in cytokine-secreting immune cells using droplet-based microfluidics.
Q35039110Prospective identification of parasitic sequences in phage display screens
Q36278893Quantitative Affinity Determination by Fluorescence Anisotropy Measurements of Individual Nanoliter Droplets
Q28238121Quantitative and sensitive detection of rare mutations using droplet-based microfluidics
Q27335286Rapid and continuous magnetic separation in droplet microfluidic devices
Q42198846Rapid detection of bacteriophages in starter culture using water-in-oil-in-water emulsion microdroplets
Q39455779Rapid purification of cell encapsulated hydrogel beads from oil phase to aqueous phase in a microfluidic device
Q38911500Reactions in ultra-small droplets by tip-assisted chemistry.
Q30612163Real-time monitoring of quorum sensing in 3D-printed bacterial aggregates using scanning electrochemical microscopy
Q37859282Recent advances in micro reaction technology
Q37963804Recent advances in single-molecule detection on micro- and nano-fluidic devices
Q42745863Remotely controllable liquid marbles.
Q30252735Review: Microbial analysis in dielectrophoretic microfluidic systems
Q53624894Scaling up the production of colloidal nanocrystals: should we increase or decrease the reaction volume?
Q26741325Selection platforms for directed evolution in synthetic biology
Q51540991Selective droplet coalescence using microfluidic systems.
Q58609238Self-Orienting Hydrogel Micro-Buckets as Novel Cell Carriers
Q47433270Sequential Coalescence Enabled Two-Step Microreactions in Triple-Core Double-Emulsion Droplets Triggered by an Electric Field
Q34057008Simple and cheap microfluidic devices for the preparation of monodisperse emulsions
Q45132221Simple modular systems for generation of droplets on demand.
Q30433182Single-cell analysis and sorting using droplet-based microfluidics
Q36215738Single-cell barcoding and sequencing using droplet microfluidics
Q91990341Single-molecule detection of deoxyribonucleoside triphosphates in microdroplets
Q37997371Single-molecule emulsion PCR in microfluidic droplets
Q94140122Size-Adjustable Microdroplets Generation Based on Microinjection
Q34025530Stationary nanoliter droplet array with a substrate of choice for single adherent/nonadherent cell incubation and analysis
Q58738229Structural Formation of Oil-in-Water (O/W) and Water-in-Oil-in-Water (W/O/W) Droplets in PDMS Device Using Protrusion Channel without Hydrophilic Surface Treatment
Q35767365Supracolloidal Architectures Self-Assembled in Microdroplets.
Q57354048Supramolecular Polymer Networks: Preparation, Properties, and Potential
Q40976638Supramolecular hydrogel microcapsules via cucurbit[8]uril host-guest interactions with triggered and UV-controlled molecular permeability
Q37346809Surfactant adsorption kinetics in microfluidics
Q53129314Surfactant induced autophobing.
Q57100987Symmetry-breaking magnetic fields create a vortex fluid that exhibits a negative viscosity, active wetting, and strong mixing
Q51529619Synthesis of a 3D graphite microball using a microfluidic droplet generator and its polymer composite with core-shell structure.
Q53319534Synthesis of new hydrophilic rhodamine based enzymatic substrates compatible with droplet-based microfluidic assays.
Q35638364The dynamics and stability of lubricating oil films during droplet transport by electrowetting in microfluidic devices
Q51494678The microenvironment of double emulsions in rectangular microchannels.
Q30361912The microfluidic jukebox.
Q39451097The potential impact of droplet microfluidics in biology
Q46093188The pumping lid: investigating multi-material 3D printing for equipment-free, programmable generation of positive and negative pressures for microfluidic applications
Q47320716Throughput enhancement of parallel step emulsifier devices by shear-free and efficient nozzle clearance
Q51222644Transitioning from multi-phase to single-phase microfluidics for long-term culture and treatment of multicellular spheroids.
Q50460352Ultra-small droplet generation via volatile component evaporation.
Q51549195Ultrafast microscopy of microfluidics: compressed sensing and remote detection.
Q27343150Ultrahigh-throughput discovery of promiscuous enzymes by picodroplet functional metagenomics
Q36185038Ultrahigh-throughput-directed enzyme evolution by absorbance-activated droplet sorting (AADS).
Q53503802Ultrasonically treated liquid interfaces for progress in cleaning and separation processes.
Q83455047Ultrasound and microstructures--a promising combination?
Q91878559Vaporizable endoskeletal droplets via tunable interfacial melting transitions
Q30514211Vimentin networks at tunable ion-concentration in microfluidic drops
Q47219004Viscosity based droplet size controlling in negative pressure driven droplets generator for large-scale particle synthesis
Q51529342Wetting-induced formation of controllable monodisperse multiple emulsions in microfluidics.
Q96128123μdroPi: A Hand-Held Microfluidic Droplet Imager and Analyzer Built on Raspberry Pi

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