Quantitative and sensitive detection of rare mutations using droplet-based microfluidics

scientific article (publication date: 7 July 2011)

Quantitative and sensitive detection of rare mutations using droplet-based microfluidics is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1039/C1LC20128J
P3181OpenCitations bibliographic resource ID1223134
P698PubMed publication ID21594292
P5875ResearchGate publication ID51148252

P50authorDeniz PekinQ58807080
Pierre Laurent-PuigQ37067941
Jean-Christophe BaretQ51518721
Linas MazutisQ55135212
Valerie TalyQ56490764
P2093author name stringAndrew D Griffiths
Jonathan W Larson
Abdeslam El Harrak
Darren R Link
Delphine Le Corre
Yousr Skhiri
J Brian Hutchison
Florian Millot
Chaouki Ben Salem
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Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cellsQ33510334
Microdroplets in microfluidics: an evolving platform for discoveries in chemistry and biologyQ33613844
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Sensitive digital quantification of DNA methylation in clinical samplesQ33761814
A commercial real-time PCR kit provides greater sensitivity than direct sequencing to detect KRAS mutations: a morphology-based approach in colorectal carcinomaQ33813835
Comparison of Sanger sequencing, pyrosequencing, and melting curve analysis for the detection of KRAS mutations: diagnostic and clinical implicationsQ33947050
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Sensitive sequencing method for KRAS mutation detection by PyrosequencingQ35789986
Mutation detection, interpretation, and applications in the clinical laboratory settingQ36097396
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Digital quantification of mutant DNA in cancer patients.Q36667676
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On-chip, real-time, single-copy polymerase chain reaction in picoliter dropletsQ39816930
On-chip single-copy real-time reverse-transcription PCR in isolated picoliter dropletsQ39834835
Pyrosequencing method to detect KRAS mutation in formalin-fixed and paraffin-embedded tumor tissues.Q39847938
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High-throughput single copy DNA amplification and cell analysis in engineered nanoliter dropletsQ46646435
Continuous-flow polymerase chain reaction of single-copy DNA in microfluidic microdropletsQ47198269
Biocompatible surfactants for water-in-fluorocarbon emulsions.Q47330807
Genetics: Predictive value of KRAS mutations in chemoresistant CRC.Q47684766
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BEAMing up for detection and quantification of rare sequence variants.Q51283236
Single-molecule reverse transcription polymerase chain reaction using water-in-oil emulsion.Q51335191
Multi-step microfluidic droplet processing: kinetic analysis of an in vitro translated enzyme.Q51563417
Advances in approaches to DNA-based diagnostics.Q51605223
Should oncologists be aware in their clinical practice of KRAS molecular analysis?Q54391227
Circulating free tumor DNA and colorectal cancer.Q54411834
Detection of KRAS mutations in colorectal carcinoma patients with an integrated PCR/sequencing and real-time PCR approach.Q54415409
Contamination-free continuous flow microfluidic polymerase chain reaction for quantitative and clinical applications.Q54661600
Single-molecule PCR using water-in-oil emulsion.Q54778235
Formation of dispersions using “flow focusing” in microchannelsQ57258632
Beyond the KRAS testQ58408207
P4510describes a project that usesmicrofluidicsQ138845
P433issue13
P407language of work or nameEnglishQ1860
P921main subjectmicrofluidicsQ138845
P304page(s)2156-66
P577publication date2011-07-07
P1433published inLab on a ChipQ3214277
P1476titleQuantitative and sensitive detection of rare mutations using droplet-based microfluidics
P478volume11

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