Liquid biopsy for detection of actionable oncogenic mutations in human cancers and electric field induced release and measurement liquid biopsy (eLB)

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Liquid biopsy for detection of actionable oncogenic mutations in human cancers and electric field induced release and measurement liquid biopsy (eLB) is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1039/C5AN01863C
P932PMC publication ID4701580
P698PubMed publication ID26645892

P50authorDavid WongQ91719683
P2093author name stringDavid Chia
Fang Wei
Michael Tu
P2860cites workThe COSMIC (Catalogue of Somatic Mutations in Cancer) database and websiteQ24645514
The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATPQ24649549
PCR-based methods for the enrichment of minority alleles and mutationsQ24657701
Liquid biopsies: genotyping circulating tumor DNAQ27010159
EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapyQ27824812
Double-stranded DNA in exosomes: a novel biomarker in cancer detectionQ28237711
Quantitative and sensitive detection of rare mutations using droplet-based microfluidicsQ28238121
Blood-based analyses of cancer: circulating tumor cells and circulating tumor DNAQ28239638
Detection of mutations in EGFR in circulating lung-cancer cellsQ29615033
COSMIC: exploring the world's knowledge of somatic mutations in human cancerQ29615725
Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNAQ29620083
Isolation and retrieval of circulating tumor cells using centrifugal forces.Q30535350
Detection of p53 and K-ras mutations in sputum of individuals exposed to smoky coal emissions in Xuan Wei County, ChinaQ31132051
Electrochemical sensor for multiplex biomarkers detectionQ33563305
Noninvasive saliva-based EGFR gene mutation detection in patients with lung cancer.Q33735738
Activating and resistance mutations of EGFR in non-small-cell lung cancer: role in clinical response to EGFR tyrosine kinase inhibitorsQ33769838
Somatic mutation screening: identification of individuals harboring K-ras mutations with the use of plasma DNA.Q33904626
The origin of oncogenic mutations: where is the primary damage?Q33920599
Secondary somatic mutations restoring BRCA1/2 predict chemotherapy resistance in hereditary ovarian carcinomas.Q33944203
Comparison of Sanger sequencing, pyrosequencing, and melting curve analysis for the detection of KRAS mutations: diagnostic and clinical implicationsQ33947050
Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancerQ34039531
A prospective, molecular epidemiology study of EGFR mutations in Asian patients with advanced non-small-cell lung cancer of adenocarcinoma histology (PIONEER)Q34041754
Detection and quantification of mutations in the plasma of patients with colorectal tumorsQ34132363
Microfluidic, marker-free isolation of circulating tumor cells from blood samplesQ34263808
Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trialQ34271566
Noninvasive identification and monitoring of cancer mutations by targeted deep sequencing of plasma DNA.Q34278191
Multicenter phase II study of erlotinib, an oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent or metastatic squamous cell cancer of the head and neckQ34287207
Liquid biopsy: monitoring cancer-genetics in the bloodQ34356149
Tumour heterogeneity in the clinicQ34372080
BEAMing: single-molecule PCR on microparticles in water-in-oil emulsionsQ34540801
Current challenges for detection of circulating tumor cells and cell-free circulating nucleic acids, and their characterization in non-small cell lung carcinoma patients. What is the best blood substrate for personalized medicine?Q34577740
Electric field directed nucleic acid hybridization on microchipsQ34743812
Combining allele-specific fluorescent probes and restriction assay in real-time PCR to achieve SNP scoring beyond allele ratios of 1:1000.Q34760338
A platform for rapid detection of multiple oncogenic mutations with relevance to targeted therapy in non-small-cell lung cancerQ34760642
KRAS mutation analysis by PCR: a comparison of two methodsQ34876437
Validation of next generation sequencing technologies in comparison to current diagnostic gold standards for BRAF, EGFR and KRAS mutational analysisQ34903217
Clinical validation of the detection of KRAS and BRAF mutations from circulating tumor DNA.Q35127938
Mutation-targeted therapy with sunitinib or everolimus in patients with advanced low-grade or intermediate-grade neuroendocrine tumours of the gastrointestinal tract and pancreas with or without cytoreductive surgery: protocol for a phase II clinicaQ35640506
Restriction endonuclease-mediated selective polymerase chain reaction: a novel assay for the detection of K-ras mutations in clinical samplesQ35753312
BEAMing up personalized medicine: mutation detection in bloodQ36040951
DNA mutation detection and analysis using miniaturized microfluidic systemsQ36344104
Detection of mutant K-ras DNA in plasma or serum of patients with colorectal cancerQ36431426
Detection of tumor PIK3CA status in metastatic breast cancer using peripheral bloodQ36497457
Detection of Ki-ras mutations in tissue and plasma samples of patients with pancreatic cancer using PNA-mediated PCR clamping and hybridisation probesQ36616092
Low percentage of KRAS mutations revealed by locked nucleic acid polymerase chain reaction: implications for treatment of metastatic colorectal cancerQ36621776
Utility of circulating B-RAF DNA mutation in serum for monitoring melanoma patients receiving biochemotherapyQ37286893
Determining lower limits of detection of digital PCR assays for cancer-related gene mutationsQ37456162
Development of a highly sensitive and specific method for detection of circulating tumor cells harboring somatic mutations in non-small-cell lung cancer patientsQ37499417
Endoscopic ultrasound-guided fine-needle aspiration biopsy and trucut biopsy in gastroenterology - An overviewQ37595056
Isolation of circulating tumor cells by dielectrophoresisQ37693324
Extracellular vesicles--vehicles that spread cancer genesQ37996375
Circulating tumor cells: liquid biopsy of cancerQ38046735
Real-time liquid biopsy in cancer patients: fact or fiction?Q38154437
Molecular analysis of circulating tumour cells-biology and biomarkersQ38180320
Mutant p53 in cancer: new functions and therapeutic opportunitiesQ38197826
Gold-nanoparticle-based colorimetric discrimination of cancer-related point mutations with picomolar sensitivityQ38315299
Analysis of circulating DNA and protein biomarkers to predict the clinical activity of regorafenib and assess prognosis in patients with metastatic colorectal cancer: a retrospective, exploratory analysis of the CORRECT trialQ38385410
KRAS mutation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancerQ38432430
Colorectal cancer screening by detection of altered human DNA in stool: feasibility of a multitarget assay panelQ38463506
Single-point mutation detection in RNA extracts using gold nanoparticles modified with hydrophobic molecular beacon-like structuresQ39027262
Competitive allele specific TaqMan PCR for KRAS, BRAF and EGFR mutation detection in clinical formalin fixed paraffin embedded samples.Q39378163
Detection of DNA mutations by fluorescence resonance energy transfer-based preferential homoduplex formation assayQ39654439
BEAMing and Droplet Digital PCR Analysis of Mutant IDH1 mRNA in Glioma Patient Serum and Cerebrospinal Fluid Extracellular Vesicles.Q40126434
Multiplex picodroplet digital PCR to detect KRAS mutations in circulating DNA from the plasma of colorectal cancer patients.Q40130589
A simple method for detecting single base substitutions and its application to HLA-DPB1 typingQ40399531
Circulating tumor DNA outperforms circulating tumor cells for KRAS mutation detection in thoracic malignanciesQ41484128
Genotypic selection methods for the direct analysis of point mutationsQ41645720
Comparison of high resolution melting analysis, pyrosequencing, next generation sequencing and immunohistochemistry to conventional Sanger sequencing for the detection of p.V600E and non-p.V600E BRAF mutationsQ41874659
Bio/abiotic interface constructed from nanoscale DNA dendrimer and conducting polymer for ultrasensitive biomolecular diagnosis.Q42944278
Challenges in circulating tumour cell researchQ43500645
Gold nanoparticles-based biosensing of single nucleotide DNA mutationsQ43908354
Real-time quantitative PCR analysis can be used as a primary screen to identify patients with CML treated with imatinib who have BCR-ABL kinase domain mutationsQ44980758
Evaluation of circulating tumor cells and circulating tumor DNA in non-small cell lung cancer: association with clinical endpoints in a phase II clinical trial of pertuzumab and erlotinibQ46504066
Phase II study of sunitinib malate, an oral multitargeted tyrosine kinase inhibitor, in patients with metastatic breast cancer previously treated with an anthracycline and a taxaneQ46696565
Next-generation sequencing: methodology and applicationQ46756992
Toward point-of-care testing for JAK2 V617F mutation on a microchip.Q51486044
DNA mutation detection with chip-based temperature gradient capillary electrophoresis using a slantwise radiative heating system.Q51578502
Achieving differentiation of single-base mutations through hairpin oligonucleotide and electric potential control.Q51599711
Noninvasive diagnosis of actionable mutations by deep sequencing of circulating free DNA in lung cancer from never-smokers: a proof-of-concept study from BioCAST/IFCT-1002.Q51711228
Quantitative cell-free DNA, KRAS, and BRAF mutations in plasma from patients with metastatic colorectal cancer during treatment with cetuximab and irinotecan.Q54537674
Detection of EGFR gene mutation in lung cancer by mutant-enriched polymerase chain reaction assay.Q54623807
Ras oncogene mutations in urine sediments of patients with bladder cancer.Q54762488
Detection of exosomal biomarker by electric field-induced release and measurement (EFIRM).Q55358450
High-throughput oncogene mutation profiling in human cancerQ57693480
Electric-field assisted immobilization and hybridization of DNA oligomers on thin-film microchipsQ58853392
Detection of K-ras oncogene mutations in bronchoalveolar lavage fluid for lung cancer diagnosisQ71896504
Enrichment methods for mutation detectionQ73808619
Analysis of circulating tumor DNA in plasma at diagnosis and during follow-up of lung cancer patientsQ74020294
P433issue2
P921main subjectbiopsyQ179991
P304page(s)393-402
P577publication date2015-12-08
P1433published inAnalystQ969812
P1476titleLiquid biopsy for detection of actionable oncogenic mutations in human cancers and electric field induced release and measurement liquid biopsy (eLB)
P478volume141

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cites work (P2860)
Q49502117Advances in liquid biopsy on-chip for cancer management: Technologies, biomarkers, and clinical analysis.
Q58544279Applications of Nanomaterials for Immunosensing
Q61798225Digital polymerase chain reaction for detecting c-MYC copy number gain in tissue and cell-free plasma samples of colorectal cancer patients
Q46630766Electric Field-Induced Disruption and Releasing Viable Content from Extracellular Vesicles.
Q28069566Emerging technologies for salivaomics in cancer detection
Q38749038Gastric cancer management: Kinases as a target therapy
Q52560940High Serum Level of Soluble Programmed Death Ligand 1 is Associated With a Poor Prognosis in Hodgkin Lymphoma.
Q39142265Liquid Biopsy for Cancer: Circulating Tumor Cells, Circulating Free DNA or Exosomes?
Q90473208Lnc-PCDH9-13:1 Is a Hypersensitive and Specific Biomarker for Early Hepatocellular Carcinoma
Q36188885Performance of Streck cfDNA Blood Collection Tubes for Liquid Biopsy Testing
Q58790057Promising clinical application of ctDNA in evaluating immunotherapy efficacy
Q55009692Update on the types and usage of liquid biopsies in the clinical setting: a systematic review.

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