| scholarly article | Q13442814 |
| P356 | DOI | 10.1373/CLINCHEM.2013.206359 |
| P698 | PubMed publication ID | 23938455 |
| P50 | author | Pierre Laurent-Puig | Q37067941 |
| Valerie Taly | Q56490764 | ||
| Helene Blons | Q57044451 | ||
| Deniz Pekin | Q58807080 | ||
| P2093 | author name string | Andrew D Griffiths | |
| Xinyu Li | |||
| Darren R Link | |||
| Olivier Bouché | |||
| Leonor Benhaim | |||
| Bruno Landi | |||
| Delphine Le Corre | |||
| J Brian Hutchison | |||
| Steve K Kotsopoulos | |||
| Karine Pallier | |||
| Ivan Atochin | |||
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | patient | Q181600 |
| colorectal cancer | Q188874 | ||
| colorectal carcinoma | Q25493920 | ||
| P304 | page(s) | 1722-1731 | |
| P577 | publication date | 2013-08-12 | |
| P1433 | published in | Clinical Chemistry | Q849687 |
| P1476 | title | Multiplex picodroplet digital PCR to detect KRAS mutations in circulating DNA from the plasma of colorectal cancer patients | |
| P478 | volume | 59 |
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| Q48143961 | A novel cell line generated using the CRISPR/Cas9 technology as universal quality control material for KRAS G12V mutation testing. |
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| Q39425159 | An improved digital polymerase chain reaction protocol to capture low-copy KRAS mutations in plasma cell-free DNA by resolving 'subsampling' issues. |
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| Q90467246 | Automated size selection for short cell-free DNA fragments enriches for circulating tumor DNA and improves error correction during next generation sequencing |
| Q36233903 | Base-Position Error Rate Analysis of Next-Generation Sequencing Applied to Circulating Tumor DNA in Non-Small Cell Lung Cancer: A Prospective Study. |
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