scholarly article | Q13442814 |
P2093 | author name string | Lei Yang | |
Ying Sun | |||
Q Ping Dou | |||
Bing Yan | |||
Shumei Zhai | |||
Qiuzhi Cindy Cui | |||
P2860 | cites work | Clioquinol inhibits peroxide-mediated toxicity through up-regulation of phosphoinositol-3-kinase and inhibition of p53 activity | Q40030779 |
Clioquinol, a therapeutic agent for Alzheimer's disease, has proteasome-inhibitory, androgen receptor-suppressing, apoptosis-inducing, and antitumor activities in human prostate cancer cells and xenografts | Q40169646 | ||
Novel Schiff base copper complexes of quinoline-2 carboxaldehyde as proteasome inhibitors in human prostate cancer cells | Q40204682 | ||
Anticancer activity of the antibiotic clioquinol | Q40434343 | ||
Novel dipeptidyl proteasome inhibitors overcome Bcl-2 protective function and selectively accumulate the cyclin-dependent kinase inhibitor p27 and induce apoptosis in transformed, but not normal, human fibroblasts | Q40979308 | ||
Anti-proliferative effects and phenotypic alterations induced by 8-hydroxyquinoline in melanoma cell lines | Q41753857 | ||
Differentiation-inducing quinolines as experimental breast cancer agents in the MCF-7 human breast cancer cell model | Q41913417 | ||
Clioquinol, a drug for Alzheimer's disease specifically interfering with brain metal metabolism: structural characterization of its zinc(II) and copper(II) complexes | Q44944109 | ||
Clioquinol mediates copper uptake and counteracts copper efflux activities of the amyloid precursor protein of Alzheimer's disease | Q45091101 | ||
Stoichiometry and conditional stability constants of Cu(II) or Zn(II) clioquinol complexes; implications for Alzheimer's and Huntington's disease therapy | Q45304635 | ||
Clioquinol inhibits the proteasome and displays preclinical activity in leukemia and myeloma | Q46406532 | ||
Preparation and study of new poly-8-hydroxyquinoline chelators for an anti-Alzheimer strategy. | Q46924835 | ||
Quantitative analysis of copper, zinc and copper/zinc ratio in selected human brain tumors | Q48297275 | ||
Copper and ceruloplasmin status in serum of prostate and colon cancer patients | Q73301562 | ||
p53-dependent induction of apoptosis by proteasome inhibitors | Q73334980 | ||
Activation of a cysteine protease in MCF-7 and T47D breast cancer cells during beta-lapachone-mediated apoptosis | Q73492333 | ||
Concentrations of Fe, Cu and Zn in breast tissue: a synchrotron XRF study | Q74581339 | ||
Importance of the different proteolytic sites of the proteasome and the efficacy of inhibitors varies with the protein substrate | Q82458556 | ||
Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells | Q21195237 | ||
The role of the ubiquitination-proteasome pathway in breast cancer: applying drugs that affect the ubiquitin-proteasome pathway to the therapy of breast cancer | Q24794927 | ||
Synthesis and cytotoxicity evaluation of some 8-hydroxyquinoline derivatives | Q28139997 | ||
Potential for proteasome inhibition in the treatment of cancer | Q28186033 | ||
The ubiquitin-proteasome pathway: on protein death and cell life | Q29619270 | ||
Discovery of a new family of bis-8-hydroxyquinoline substituted benzylamines with pro-apoptotic activity in cancer cells: synthesis, structure-activity relationship, and action mechanism studies. | Q31155592 | ||
Organic copper complexes as a new class of proteasome inhibitors and apoptosis inducers in human cancer cells | Q33199028 | ||
Inhibition of prostate cancer cellular proteasome activity by a pyrrolidine dithiocarbamate-copper complex is associated with suppression of proliferation and induction of apoptosis | Q33217605 | ||
Pipes and wiring: the regulation of copper uptake and distribution in yeast. | Q33798087 | ||
Treatment of metastatic cancer with tetrathiomolybdate, an anticopper, antiangiogenic agent: Phase I study. | Q33888604 | ||
Cellular copper transport and metabolism | Q33913533 | ||
Tumour vasculature as a target for anticancer therapy. | Q33920565 | ||
Copper control as an antiangiogenic anticancer therapy: lessons from treating Wilson's disease | Q34083391 | ||
Proteasome inhibitors as potential novel anticancer agents | Q34086759 | ||
Phase II trial of tetrathiomolybdate in patients with advanced kidney cancer | Q34195781 | ||
Proteasome from Thermoplasma acidophilum: a threonine protease | Q34309062 | ||
Serum and tissue trace metal levels in lung cancer | Q34533791 | ||
Angiogenesis: pathological, prognostic, and growth-factor pathways and their link to trial design and anticancer drugs | Q34572035 | ||
Acrodermatitis enteropathica and an overview of zinc metabolism | Q36693109 | ||
The proteasome as a potential target for novel anticancer drugs and chemosensitizers | Q36695969 | ||
Ni(II), Cu(II), and Zn(II) diethyldithiocarbamate complexes show various activities against the proteasome in breast cancer cells. | Q36953350 | ||
P433 | issue | 2 | |
P921 | main subject | copper | Q753 |
P304 | page(s) | 259-269 | |
P577 | publication date | 2009-10-07 | |
P1433 | published in | Journal of Biological Inorganic Chemistry | Q3186899 |
P1476 | title | Tumor cellular proteasome inhibition and growth suppression by 8-hydroxyquinoline and clioquinol requires their capabilities to bind copper and transport copper into cells | |
P478 | volume | 15 |
Q36869057 | 1,10-Phenanthroline promotes copper complexes into tumor cells and induces apoptosis by inhibiting the proteasome activity. |
Q93017778 | A Proteomic View of Cellular Responses to Anticancer Quinoline-Copper Complexes |
Q93257503 | A combination of clioquinol, zinc and copper increases the abundance and function of breast cancer resistance protein in human brain microvascular endothelial cells |
Q89638804 | A systematic review and meta-analysis on the association of serum and tumor tissue iron and risk of breast cancer |
Q39307579 | Biological and cytoselective anticancer properties of copper(II)-polypyridyl complexes modulated by auxiliary methylated glycine ligand |
Q39572385 | Clioquinol induces cytoplasmic clearance of the X-linked inhibitor of apoptosis protein (XIAP): therapeutic indication for prostate cancer. |
Q35526682 | Comparative proteomic analysis of the molecular responses of mouse macrophages to titanium dioxide and copper oxide nanoparticles unravels some toxic mechanisms for copper oxide nanoparticles in macrophages. |
Q38667138 | Copper (II) complexes of bidentate ligands exhibit potent anti-cancer activity regardless of platinum sensitivity status |
Q37970312 | Copper complexes as therapeutic agents |
Q37698887 | Copper is a potent inhibitor of both the canonical and non-canonical NFκB pathways. |
Q33666645 | DNA Cleavage, Cytotoxic Activities, and Antimicrobial Studies of Ternary Copper(II) Complexes of Isoxazole Schiff Base and Heterocyclic Compounds |
Q98289890 | Effects of 8-hydroxyquinoline-coated graphene oxide on cell death and apoptosis in MCF-7 and MCF-10 breast cell lines |
Q34219760 | Exploiting innate immune cell activation of a copper-dependent antimicrobial agent during infection |
Q36775000 | From fighting depression to conquering tumors: a novel tricyclic thiazepine compound as a tubulin polymerization inhibitor |
Q36367042 | Gastrointestinal localization of metronidazole by a lactobacilli-inspired tetramic acid motif improves treatment outcomes in the hamster model of Clostridium difficile infection |
Q39392617 | Gluconjugates of 8-hydroxyquinolines as potential anti-cancer prodrugs |
Q39240549 | Glycosylated copper(II) ionophores as prodrugs for β-glucosidase activation in targeted cancer therapy. |
Q39604034 | High cytotoxicity of dihalo-substituted 8-quinolinolato-lanthanides |
Q38719744 | In Vitro DNA-Binding, Anti-Oxidant and Anticancer Activity of Indole-2-Carboxylic Acid Dinuclear Copper(II) Complexes |
Q39609488 | Investigation on the pharmacological profile of antimony(III) complexes with hydroxyquinoline derivatives: anti-trypanosomal activity and cytotoxicity against human leukemia cell lines |
Q47098444 | Metal-based proteasomal deubiquitinase inhibitors as potential anticancer agents |
Q39674393 | N-Acetylcysteine interacts with copper to generate hydrogen peroxide and selectively induce cancer cell death |
Q36822739 | New applications of old metal-binding drugs in the treatment of human cancer |
Q39110246 | Novel clioquinol and its analogous platinum complexes: importance, role of the halogen substitution and the hydroxyl group of the ligand. |
Q46449120 | Novel mitochondria targeted copper(ii) complexes of ferrocenyl terpyridine and anticancer active 8-hydroxyquinolines showing remarkable cytotoxicity, DNA and protein binding affinity. |
Q35096909 | Reutericyclin and related analogues kill stationary phase Clostridium difficile at achievable colonic concentrations |
Q53214265 | Serum Copper and Zinc Levels Among Iranian Colorectal Cancer Patients. |
Q85036779 | Serum total oxidant/antioxidant status and trace element levels in breast cancer patients |
Q39000218 | Structural characterization and biological evaluation of a clioquinol-ruthenium complex with copper-independent antileukaemic activity |
Q47631097 | Targeting the ubiquitin-proteasome system for cancer treatment: discovering novel inhibitors from nature and drug repurposing |
Q37333839 | The antiparasitic clioquinol induces apoptosis in leukemia and myeloma cells by inhibiting histone deacetylase activity |
Q37206068 | Turning tumor-promoting copper into an anti-cancer weapon via high-throughput chemistry |
Search more.