Proteasome from Thermoplasma acidophilum: a threonine protease

scientific article

Proteasome from Thermoplasma acidophilum: a threonine protease is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1126/SCIENCE.7725107
P698PubMed publication ID7725107

P2093author name stringHuber R
Baumeister W
Seemüller E
Lupas A
Stock D
Löwe J
P433issue5210
P407language of work or nameEnglishQ1860
P304page(s)579-582
P577publication date1995-04-01
P1433published inScienceQ192864
P1476titleProteasome from Thermoplasma acidophilum: a threonine protease
P478volume268

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cites work (P2860)
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Q34298336Puromycin-sensitive aminopeptidase. Sequence analysis, expression, and functional characterization
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Q43868830Sequencing of amphioxus PSMB5/8 gene and phylogenetic position of agnathan sequences
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Q54097243Species variation in ATP-dependent protein degradation: protease profiles differ between mycobacteria and protease functions differ between Mycobacterium smegmatis and Escherichia coli.
Q71824471Specific inhibition of the chymotrypsin-like activity of the proteasome induces a bipolar morphology in neuroblastoma cells
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Q47919213Stress induction of the Bacillus subtilis clpP gene encoding a homologue of the proteolytic component of the Clp protease and the involvement of ClpP and ClpX in stress tolerance
Q27661050Structural Basis for the Activity and Substrate Specificity of Fluoroacetyl-CoA Thioesterase FlK
Q27658058Structural Models for Interactions between the 20S Proteasome and Its PAN/19S Activators
Q33548213Structural and energetic determinants of the S1-site specificity in serine proteases
Q47944567Structural and functional analysis of the six regulatory particle triple-A ATPase subunits from the Arabidopsis 26S proteasome
Q27661499Structural basis for the assembly and gate closure mechanisms of the Mycobacterium tuberculosis 20S proteasome
Q38081952Structural biology of the proteasome
Q37396451Structural insights into proteasome activation by the 19S regulatory particle
Q37640400Structural insights into the functional cycle of the ATPase module of the 26S proteasome
Q27619651Structural insights into the mechanism of intramolecular proteolysis
Q33737328Structure and mechanism of action of the protease that degrades small, acid-soluble spore proteins during germination of spores of Bacillus species.
Q27641494Structure and reactivity of an asymmetric complex between HslV and I-domain deleted HslU, a prokaryotic homolog of the eukaryotic proteasome
Q41535692Structure and structure formation of the 20S proteasome
Q27735081Structure of 20S proteasome from yeast at 2.4 A resolution
Q27660222Structure of a Blm10 Complex Reveals Common Mechanisms for Proteasome Binding and Gate Opening
Q35097624Substrate access and processing by the 20S proteasome core particle
Q41027912Substrate binding and sequence preference of the proteasome revealed by active-site-directed affinity probes
Q24311953Subunit arrangement in the human 20S proteasome
Q34891158Subunit oligomerization and substrate recognition of the Escherichia coli ClpYQ (HslUV) protease implicated by in vivo protein-protein interactions in the yeast two-hybrid system
Q39702656Subunit topology of two 20S proteasomes from Haloferax volcanii
Q57007289Synthetic peptide conjugates—tailor-made probes for the biology of protein modification and protein processing
Q24300473Taspase1: a threonine aspartase required for cleavage of MLL and proper HOX gene expression
Q37083471Tea polyphenols and their roles in cancer prevention and chemotherapy
Q37070437Tea polyphenols, their biological effects and potential molecular targets
Q48041490The 20S proteasome gene family in Arabidopsis thaliana.
Q39568209The 20S proteasome of Streptomyces coelicolor.
Q28348872The ATP-dependent CodWX (HslVU) protease in Bacillus subtilis is an N-terminal serine protease
Q43993783The C-terminal tails of HslU ATPase act as a molecular switch for activation of HslV peptidase
Q73065840The Leishmania mexicana proteasome
Q33658714The Mycobacterium tuberculosis proteasome active site threonine is essential for persistence yet dispensable for replication and resistance to nitric oxide
Q38132669The RNA exosome and proteasome: common principles of degradation control
Q33785026The Saccharomyces cerevisiae ubiquitin-proteasome system
Q47273976The Y. bercovieri Anbu crystal structure sheds light on the evolution of highly (pseudo)symmetric multimers.
Q27939678The active sites of the eukaryotic 20 S proteasome and their involvement in subunit precursor processing
Q48964378The antitumor drug aclacinomycin A, which inhibits the degradation of ubiquitinated proteins, shows selectivity for the chymotrypsin-like activity of the bovine pituitary 20 S proteasome
Q36386004The archaeal proteasome is regulated by a network of AAA ATPases
Q33187465The caspase-like sites of proteasomes, their substrate specificity, new inhibitors and substrates, and allosteric interactions with the trypsin-like sites.
Q30779094The catalytic sites of 20S proteasomes and their role in subunit maturation: a mutational and crystallographic study
Q70920514The fates of proteins in cells
Q38819083The fine-tuning of proteolytic pathways in Alzheimer's disease
Q48072601The first characterization of a eubacterial proteasome: the 20S complex of Rhodococcus
Q54567772The human alpha-type proteasomal subunit HsC8 forms a double ringlike structure, but does not assemble into proteasome-like particles with the beta-type subunits HsDelta or HsBPROS26.
Q36065854The pore of activated 20S proteasomes has an ordered 7-fold symmetric conformation
Q73204803The proteasome
Q33796158The proteasome activator 11 S REG (PA28) and class I antigen presentation
Q95650650The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges
Q33700949The proteasome, a novel protease regulated by multiple mechanisms
Q33785021The proteasome: a macromolecular assembly designed for controlled proteolysis
Q36862775The proteasome: a macromolecular assembly designed to confine proteolysis to a nanocompartment
Q34545602The proteasome: a supramolecular assembly designed for controlled proteolysis
Q29615187The proteasome: paradigm of a self-compartmentalizing protease
Q30453898The proteolytic fragments generated by vertebrate proteasomes: structural relationships to major histocompatibility complex class I binding peptides
Q27659007The quorum-quenching N-acyl homoserine lactone acylase PvdQ is an Ntn-hydrolase with an unusual substrate-binding pocket
Q30654582The role of alpha-amino group of the N-terminal serine of beta subunit for enzyme catalysis and autoproteolytic activation of glutaryl 7-aminocephalosporanic acid acylase
Q37171851The roles of the proteasome pathway in signal transduction and neurodegenerative diseases
Q51824224The solution of nitrogen inversion in amidases.
Q36545597The subunits MECL-1 and LMP2 are mutually required for incorporation into the 20S proteasome
Q28214433The transporter associated with antigen processing: function and implications in human diseases
Q37175850The tumor proteasome as a novel target for gold(III) complexes: implications for breast cancer therapy
Q28367002The ubiquitin-proteasome pathway and proteasome inhibitors
Q28305844The ubiquitin-proteasome system
Q29030764Thermoplasmatales
Q27973422Thiostrepton and derivatives exhibit antimalarial and gametocytocidal activity by dually targeting parasite proteasome and apicoplast
Q33622430Tumor cellular proteasome inhibition and growth suppression by 8-hydroxyquinoline and clioquinol requires their capabilities to bind copper and transport copper into cells
Q41062674Two-substrate association with the 20S proteasome at single-molecule level
Q27931305Ump1p is required for proper maturation of the 20S proteasome and becomes its substrate upon completion of the assembly.
Q28295493Unconventional serine proteases: variations on the catalytic Ser/His/Asp triad configuration
Q46763702VAT, the thermoplasma homolog of mammalian p97/VCP, is an N domain-regulated protein unfoldase
Q61788075Variations in proteasome subunit composition and enzymatic activity in B-lymphoma lines and normal B cells
Q93089059Visualizing Proteasome Activity and Intracellular Localization Using Fluorescent Proteins and Activity-Based Probes
Q35127936Why Ser and not Thr brokers catalysis in the trypsin fold
Q30870481Why does threonine, and not serine, function as the active site nucleophile in proteasomes?
Q30814900alpha5 subunit in Trypanosoma brucei proteasome can self-assemble to form a cylinder of four stacked heptamer rings
Q28282975cDNA cloning of p42, a shared subunit of two proteasome regulatory proteins, reveals a novel member of the AAA protein family
Q22253889cDNA cloning, expression, and functional characterization of PI31, a proline-rich inhibitor of the proteasome

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