The RNA exosome and proteasome: common principles of degradation control

scientific article published on 29 August 2013

The RNA exosome and proteasome: common principles of degradation control is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1023748083
P356DOI10.1038/NRM3657
P698PubMed publication ID23989960

P2093author name stringDebora L Makino
Felix Halbach
Elena Conti
P2860cites workA new yeast poly(A) polymerase complex involved in RNA quality controlQ21146099
MPP6 is an exosome-associated RNA-binding protein involved in 5.8S rRNA maturationQ24300437
C1D and hMtr4p associate with the human exosome subunit PM/Scl-100 and are involved in pre-rRNA processingQ24301838
Reconstitution, activities, and structure of the eukaryotic RNA exosomeQ24337238
The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substratesQ24337929
Functions of the exosome in rRNA, snoRNA and snRNA synthesisQ24529845
Ski7p G protein interacts with the exosome and the Ski complex for 3'-to-5' mRNA decay in yeastQ24535685
PA200, a nuclear proteasome activator involved in DNA repairQ24536971
Polynucleotide phosphorylase functions as both an exonuclease and a poly(A) polymerase in spinach chloroplastsQ24550883
The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleasesQ24600315
The N-terminal PIN domain of the exosome subunit Rrp44 harbors endonuclease activity and tethers Rrp44 to the yeast core exosomeQ24644651
Docking of the proteasomal ATPases' carboxyl termini in the 20S proteasome's alpha ring opens the gate for substrate entryQ24674433
Architecture of the yeast Rrp44 exosome complex suggests routes of RNA recruitment for 3' end processingQ24675358
Structural basis for the activation of 20S proteasomes by 11S regulatorsQ27628418
Structure of the active subunit of the yeast exosome core, Rrp44: diverse modes of substrate recruitment in the RNase II nuclease familyQ27650186
The yeast exosome functions as a macromolecular cage to channel RNA substrates for degradationQ27658030
Structure of a Blm10 Complex Reveals Common Mechanisms for Proteasome Binding and Gate OpeningQ27660222
Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complexQ27683886
The yeast ski complex: crystal structure and RNA channeling to the exosome complexQ27685388
Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolutionQ27730197
Structure of 20S proteasome from yeast at 2.4 A resolutionQ27735081
Structure of the proteasome activator REGalpha (PA28alpha)Q27748362
Structural framework for the mechanism of archaeal exosomes in RNA processingQ81476134
Global analysis of protein expression in yeastQ27860658
The ubiquitin systemQ27860803
Endonucleolytic RNA cleavage by a eukaryotic exosomeQ27930673
Blm3 is part of nascent proteasomes and is involved in a late stage of nuclear proteasome assemblyQ27930761
The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleasesQ27930922
The yeast antiviral proteins Ski2p, Ski3p, and Ski8p exist as a complex in vivoQ27931202
Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymeraseQ27932117
RNA degradation by the exosome is promoted by a nuclear polyadenylation complexQ27932438
Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6pQ27932846
Rrp6p, the yeast homologue of the human PM-Scl 100-kDa autoantigen, is essential for efficient 5.8 S rRNA 3' end formationQ27933100
RNA channelling by the eukaryotic exosomeQ27933474
RPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome: a negative feedback circuitQ27933746
The PMC2NT domain of the catalytic exosome subunit Rrp6p provides the interface for binding with its cofactor Rrp47p, a nucleic acid-binding proteinQ27934035
The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities.Q27934866
Rrp47p is an exosome-associated protein required for the 3' processing of stable RNAs.Q27935348
A single subunit, Dis3, is essentially responsible for yeast exosome core activityQ27935552
The proteasome regulatory particle alters the SAGA coactivator to enhance its interactions with transcriptional activators.Q27935912
Activation of a membrane-bound transcription factor by regulated ubiquitin/proteasome-dependent processing.Q27937925
Exosome-mediated recognition and degradation of mRNAs lacking a termination codonQ27939297
The nuclear RNA polymerase II surveillance system targets polymerase III transcriptsQ27940256
Purification of an 11 S regulator of the multicatalytic proteaseQ28202111
The exosome and the proteasome: nano-compartments for degradationQ28241383
The archaeal exosome core is a hexameric ring structure with three catalytic subunitsQ28256090
Complete subunit architecture of the proteasome regulatory particleQ28257212
Molecular architecture of the 26S proteasome holocomplex determined by an integrative approachQ28259014
The exosome: a macromolecular cage for controlled RNA degradationQ28263179
Structural basis of 3' end RNA recognition and exoribonucleolytic cleavage by an exosome RNase PH coreQ28281579
The proteasome: paradigm of a self-compartmentalizing proteaseQ29615187
The many pathways of RNA degradationQ29615760
The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa BQ29618194
Near-atomic resolution structural model of the yeast 26S proteasome.Q30524942
Poly(A) tail-dependent exonuclease AtRrp41p from Arabidopsis thaliana rescues 5.8 S rRNA processing and mRNA decay defects of the yeast ski6 mutant and is found in an exosome-sized complex in plant and yeast cellsQ30896877
The caspase-like sites of proteasomes, their substrate specificity, new inhibitors and substrates, and allosteric interactions with the trypsin-like sites.Q33187465
The exosome: a proteasome for RNA?Q33778598
mRNA stability in eukaryotesQ33885047
The 1.9 A structure of a proteasome-11S activator complex and implications for proteasome-PAN/PA700 interactions.Q33987362
Genome-wide approaches to systematically identify substrates of the ubiquitin-proteasome pathwayQ34079545
Cellular strategies of protein quality controlQ34199521
Evidence that pituitary cation-sensitive neutral endopeptidase is a multicatalytic protease complexQ34256147
Proteasome from Thermoplasma acidophilum: a threonine proteaseQ34309062
Antigen processing and presentation by the class I major histocompatibility complexQ34389698
Contribution of proteasomal beta-subunits to the cleavage of peptide substrates analyzed with yeast mutantsQ34753108
Molecular mechanisms of proteasome assemblyQ34928594
Proteasome inhibitors in cancer therapyQ34939959
Proteolysis, proteasomes and antigen presentationQ35228583
The pore of activated 20S proteasomes has an ordered 7-fold symmetric conformationQ36065854
Exo- and endoribonucleolytic activities of yeast cytoplasmic and nuclear RNA exosomes are dependent on the noncatalytic core and central channel.Q36319804
Endoproteolytic activity of the proteasomeQ36450745
RNA quality control in eukaryotesQ37005637
Polynucleotide phosphorylase and the archaeal exosome as poly(A)-polymerasesQ37051583
Catalytic mechanism and assembly of the proteasome.Q37407654
Proteasome activatorsQ37826501
Functions of the cytoplasmic exosomeQ37895570
Proteasome inhibitors: an expanding army attacking a unique targetQ37979388
Structural biology of the proteasomeQ38081952
Allosteric effects in the regulation of 26S proteasome activitiesQ38082254
The proteasome: from basic mechanisms to emerging rolesQ38096863
Widespread cotranslational formation of protein complexes.Q38329707
The direction of protein entry into the proteasome determines the variety of products and depends on the force needed to unfold its two termini.Q39264914
MHC ligands and peptide motifs: first listingQ40612811
Subcellular localization of proteasomes and their regulatory complexes in mammalian cells.Q40902473
Structural and functional characterizations of the proteasome-activating protein PA26 from Trypanosoma bruceiQ41703202
Transcriptome-wide analysis of exosome targetsQ42421964
A nonproteolytic function of the 19S regulatory subunit of the 26S proteasome is required for efficient activated transcription by human RNA polymerase II.Q42526859
Proteasomal ATPases link ubiquitylation of histone H2B to methylation of histone H3.Q44766533
20S proteasomes have the potential to keep substrates in store for continual degradation.Q50740999
A conserved processing mechanism regulates the activity of transcription factors Cubitus interruptus and NF-κBQ57851826
The 19S Regulatory Complex of the Proteasome Functions Independently of Proteolysis in Nucleotide Excision RepairQ63383896
Identification, purification, and characterization of a protein activator (PA28) of the 20 S proteasome (macropain)Q68127933
Peptide intermediates in the degradation of cellular proteins. Bestatin permits their accumulation in mouse liver in vivoQ71654020
Proteasome active sites allosterically regulate each other, suggesting a cyclical bite-chew mechanism for protein breakdownQ73075592
An N-terminal region of Sp1 targets its proteasome-dependent degradation in vitroQ77754902
The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes. Implications for understanding the degradative mechanism and antigen presentationQ77911981
Wrong PH for RNA degradationQ79487884
Proteolysis: from the lysosome to ubiquitin and the proteasomeQ81354981
P433issue10
P304page(s)654-660
P577publication date2013-08-29
P1433published inNature Reviews Molecular Cell BiologyQ1573120
P1476titleThe RNA exosome and proteasome: common principles of degradation control
P478volume14

Reverse relations

cites work (P2860)
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