scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1023748083 |
P356 | DOI | 10.1038/NRM3657 |
P698 | PubMed publication ID | 23989960 |
P2093 | author name string | Debora L Makino | |
Felix Halbach | |||
Elena Conti | |||
P2860 | cites work | A new yeast poly(A) polymerase complex involved in RNA quality control | Q21146099 |
MPP6 is an exosome-associated RNA-binding protein involved in 5.8S rRNA maturation | Q24300437 | ||
C1D and hMtr4p associate with the human exosome subunit PM/Scl-100 and are involved in pre-rRNA processing | Q24301838 | ||
Reconstitution, activities, and structure of the eukaryotic RNA exosome | Q24337238 | ||
The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates | Q24337929 | ||
Functions of the exosome in rRNA, snoRNA and snRNA synthesis | Q24529845 | ||
Ski7p G protein interacts with the exosome and the Ski complex for 3'-to-5' mRNA decay in yeast | Q24535685 | ||
PA200, a nuclear proteasome activator involved in DNA repair | Q24536971 | ||
Polynucleotide phosphorylase functions as both an exonuclease and a poly(A) polymerase in spinach chloroplasts | Q24550883 | ||
The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases | Q24600315 | ||
The N-terminal PIN domain of the exosome subunit Rrp44 harbors endonuclease activity and tethers Rrp44 to the yeast core exosome | Q24644651 | ||
Docking of the proteasomal ATPases' carboxyl termini in the 20S proteasome's alpha ring opens the gate for substrate entry | Q24674433 | ||
Architecture of the yeast Rrp44 exosome complex suggests routes of RNA recruitment for 3' end processing | Q24675358 | ||
Structural basis for the activation of 20S proteasomes by 11S regulators | Q27628418 | ||
Structure of the active subunit of the yeast exosome core, Rrp44: diverse modes of substrate recruitment in the RNase II nuclease family | Q27650186 | ||
The yeast exosome functions as a macromolecular cage to channel RNA substrates for degradation | Q27658030 | ||
Structure of a Blm10 Complex Reveals Common Mechanisms for Proteasome Binding and Gate Opening | Q27660222 | ||
Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex | Q27683886 | ||
The yeast ski complex: crystal structure and RNA channeling to the exosome complex | Q27685388 | ||
Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution | Q27730197 | ||
Structure of 20S proteasome from yeast at 2.4 A resolution | Q27735081 | ||
Structure of the proteasome activator REGalpha (PA28alpha) | Q27748362 | ||
Structural framework for the mechanism of archaeal exosomes in RNA processing | Q81476134 | ||
Global analysis of protein expression in yeast | Q27860658 | ||
The ubiquitin system | Q27860803 | ||
Endonucleolytic RNA cleavage by a eukaryotic exosome | Q27930673 | ||
Blm3 is part of nascent proteasomes and is involved in a late stage of nuclear proteasome assembly | Q27930761 | ||
The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases | Q27930922 | ||
The yeast antiviral proteins Ski2p, Ski3p, and Ski8p exist as a complex in vivo | Q27931202 | ||
Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase | Q27932117 | ||
RNA degradation by the exosome is promoted by a nuclear polyadenylation complex | Q27932438 | ||
Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6p | Q27932846 | ||
Rrp6p, the yeast homologue of the human PM-Scl 100-kDa autoantigen, is essential for efficient 5.8 S rRNA 3' end formation | Q27933100 | ||
RNA channelling by the eukaryotic exosome | Q27933474 | ||
RPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome: a negative feedback circuit | Q27933746 | ||
The PMC2NT domain of the catalytic exosome subunit Rrp6p provides the interface for binding with its cofactor Rrp47p, a nucleic acid-binding protein | Q27934035 | ||
The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities. | Q27934866 | ||
Rrp47p is an exosome-associated protein required for the 3' processing of stable RNAs. | Q27935348 | ||
A single subunit, Dis3, is essentially responsible for yeast exosome core activity | Q27935552 | ||
The proteasome regulatory particle alters the SAGA coactivator to enhance its interactions with transcriptional activators. | Q27935912 | ||
Activation of a membrane-bound transcription factor by regulated ubiquitin/proteasome-dependent processing. | Q27937925 | ||
Exosome-mediated recognition and degradation of mRNAs lacking a termination codon | Q27939297 | ||
The nuclear RNA polymerase II surveillance system targets polymerase III transcripts | Q27940256 | ||
Purification of an 11 S regulator of the multicatalytic protease | Q28202111 | ||
The exosome and the proteasome: nano-compartments for degradation | Q28241383 | ||
The archaeal exosome core is a hexameric ring structure with three catalytic subunits | Q28256090 | ||
Complete subunit architecture of the proteasome regulatory particle | Q28257212 | ||
Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach | Q28259014 | ||
The exosome: a macromolecular cage for controlled RNA degradation | Q28263179 | ||
Structural basis of 3' end RNA recognition and exoribonucleolytic cleavage by an exosome RNase PH core | Q28281579 | ||
The proteasome: paradigm of a self-compartmentalizing protease | Q29615187 | ||
The many pathways of RNA degradation | Q29615760 | ||
The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B | Q29618194 | ||
Near-atomic resolution structural model of the yeast 26S proteasome. | Q30524942 | ||
Poly(A) tail-dependent exonuclease AtRrp41p from Arabidopsis thaliana rescues 5.8 S rRNA processing and mRNA decay defects of the yeast ski6 mutant and is found in an exosome-sized complex in plant and yeast cells | Q30896877 | ||
The caspase-like sites of proteasomes, their substrate specificity, new inhibitors and substrates, and allosteric interactions with the trypsin-like sites. | Q33187465 | ||
The exosome: a proteasome for RNA? | Q33778598 | ||
mRNA stability in eukaryotes | Q33885047 | ||
The 1.9 A structure of a proteasome-11S activator complex and implications for proteasome-PAN/PA700 interactions. | Q33987362 | ||
Genome-wide approaches to systematically identify substrates of the ubiquitin-proteasome pathway | Q34079545 | ||
Cellular strategies of protein quality control | Q34199521 | ||
Evidence that pituitary cation-sensitive neutral endopeptidase is a multicatalytic protease complex | Q34256147 | ||
Proteasome from Thermoplasma acidophilum: a threonine protease | Q34309062 | ||
Antigen processing and presentation by the class I major histocompatibility complex | Q34389698 | ||
Contribution of proteasomal beta-subunits to the cleavage of peptide substrates analyzed with yeast mutants | Q34753108 | ||
Molecular mechanisms of proteasome assembly | Q34928594 | ||
Proteasome inhibitors in cancer therapy | Q34939959 | ||
Proteolysis, proteasomes and antigen presentation | Q35228583 | ||
The pore of activated 20S proteasomes has an ordered 7-fold symmetric conformation | Q36065854 | ||
Exo- and endoribonucleolytic activities of yeast cytoplasmic and nuclear RNA exosomes are dependent on the noncatalytic core and central channel. | Q36319804 | ||
Endoproteolytic activity of the proteasome | Q36450745 | ||
RNA quality control in eukaryotes | Q37005637 | ||
Polynucleotide phosphorylase and the archaeal exosome as poly(A)-polymerases | Q37051583 | ||
Catalytic mechanism and assembly of the proteasome. | Q37407654 | ||
Proteasome activators | Q37826501 | ||
Functions of the cytoplasmic exosome | Q37895570 | ||
Proteasome inhibitors: an expanding army attacking a unique target | Q37979388 | ||
Structural biology of the proteasome | Q38081952 | ||
Allosteric effects in the regulation of 26S proteasome activities | Q38082254 | ||
The proteasome: from basic mechanisms to emerging roles | Q38096863 | ||
Widespread cotranslational formation of protein complexes. | Q38329707 | ||
The direction of protein entry into the proteasome determines the variety of products and depends on the force needed to unfold its two termini. | Q39264914 | ||
MHC ligands and peptide motifs: first listing | Q40612811 | ||
Subcellular localization of proteasomes and their regulatory complexes in mammalian cells. | Q40902473 | ||
Structural and functional characterizations of the proteasome-activating protein PA26 from Trypanosoma brucei | Q41703202 | ||
Transcriptome-wide analysis of exosome targets | Q42421964 | ||
A nonproteolytic function of the 19S regulatory subunit of the 26S proteasome is required for efficient activated transcription by human RNA polymerase II. | Q42526859 | ||
Proteasomal ATPases link ubiquitylation of histone H2B to methylation of histone H3. | Q44766533 | ||
20S proteasomes have the potential to keep substrates in store for continual degradation. | Q50740999 | ||
A conserved processing mechanism regulates the activity of transcription factors Cubitus interruptus and NF-κB | Q57851826 | ||
The 19S Regulatory Complex of the Proteasome Functions Independently of Proteolysis in Nucleotide Excision Repair | Q63383896 | ||
Identification, purification, and characterization of a protein activator (PA28) of the 20 S proteasome (macropain) | Q68127933 | ||
Peptide intermediates in the degradation of cellular proteins. Bestatin permits their accumulation in mouse liver in vivo | Q71654020 | ||
Proteasome active sites allosterically regulate each other, suggesting a cyclical bite-chew mechanism for protein breakdown | Q73075592 | ||
An N-terminal region of Sp1 targets its proteasome-dependent degradation in vitro | Q77754902 | ||
The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes. Implications for understanding the degradative mechanism and antigen presentation | Q77911981 | ||
Wrong PH for RNA degradation | Q79487884 | ||
Proteolysis: from the lysosome to ubiquitin and the proteasome | Q81354981 | ||
P433 | issue | 10 | |
P304 | page(s) | 654-660 | |
P577 | publication date | 2013-08-29 | |
P1433 | published in | Nature Reviews Molecular Cell Biology | Q1573120 |
P1476 | title | The RNA exosome and proteasome: common principles of degradation control | |
P478 | volume | 14 |
Q41432701 | Characterization of the mammalian RNA exonuclease 5/NEF-sp as a testis-specific nuclear 3' → 5' exoribonuclease |
Q28073658 | CircRNAs in hematopoiesis and hematological malignancies |
Q47360746 | Conserved mRNA-binding proteomes in eukaryotic organisms. |
Q36191874 | Crystal structures of CRISPR-associated Csx3 reveal a manganese-dependent deadenylation exoribonuclease. |
Q36838271 | Exosomal Protein Deficiencies: How Abnormal RNA Metabolism Results in Childhood-Onset Neurological Diseases |
Q38765704 | Exosome-derived microRNAs contribute to prostate cancer chemoresistance. |
Q38775093 | From structures to functions: insights into exosomes as promising drug delivery vehicles |
Q91173483 | Insights into the assembly and architecture of a Staufen-mediated mRNA decay (SMD)-competent mRNP |
Q46562628 | Mature maternal mRNAs are longer than zygotic ones and have complex degradation kinetics in sea urchin |
Q37184211 | Molecular Mechanism of Processive 3' to 5' RNA Translocation in the Active Subunit of the RNA Exosome Complex |
Q42360510 | Mpp6 Incorporation in the Nuclear Exosome Contributes to RNA Channeling through the Mtr4 Helicase |
Q44010541 | Nuclear RNA Exosome at 3.1 Å Reveals Substrate Specificities, RNA Paths, and Allosteric Inhibition of Rrp44/Dis3. |
Q88004256 | Post-transcriptional regulation of gene expression and human disease |
Q62693852 | Purification of cross-linked RNA-protein complexes by phenol-toluol extraction |
Q47279037 | RNA degradation by the plant RNA exosome involves both phosphorolytic and hydrolytic activities |
Q38364656 | RNA degradation in antiviral immunity and autoimmunity |
Q27701670 | RNA degradation paths in a 12-subunit nuclear exosome complex |
Q42703646 | Regulation of Rab5 isoforms by transcriptional and post-transcriptional mechanisms in yeast |
Q33749402 | Regulatory mechanisms of RNA function: emerging roles of DNA repair enzymes. |
Q27937196 | Saccharomyces cerevisiae Ski7 Is a GTP-Binding Protein Adopting the Characteristic Conformation of Active Translational GTPases |
Q47135435 | Structural insights into the interaction of the nuclear exosome helicase Mtr4 with the preribosomal protein Nop53. |
Q27684742 | Structure of an Rrp6–RNA exosome complex bound to poly(A) RNA |
Q41412817 | Structure of the RBM7-ZCCHC8 core of the NEXT complex reveals connections to splicing factors |
Q46065809 | Telling right from wrong in life - cellular quality control |
Q92265654 | The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs |
Q41254380 | The RNA Exosome Channeling and Direct Access Conformations Have Distinct In Vivo Functions |
Q28545135 | The exosome component Rrp6 is required for RNA polymerase II termination at specific targets of the Nrd1-Nab3 pathway |
Q38303499 | The exosome-binding factors Rrp6 and Rrp47 form a composite surface for recruiting the Mtr4 helicase |
Q35029146 | The nuclear pore complex--structure and function at a glance. |
Q39950960 | The oligomeric architecture of the archaeal exosome is important for processive and efficient RNA degradation |
Q36276962 | The role of the two splice variants and extranuclear pathway on Ki-67 regulation in non-cancer and cancer cells |
Q33823191 | The use of molecular imaging combined with genomic techniques to understand the heterogeneity in cancer metastasis |
Q34221714 | Tumor-derived exosomes promote tumor progression and T-cell dysfunction through the regulation of enriched exosomal microRNAs in human nasopharyngeal carcinoma |
Q36082634 | XRN2 Links Transcription Termination to DNA Damage and Replication Stress |
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