Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach

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Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2012PNAS..109.1380L
P356DOI10.1073/PNAS.1120559109
P3181OpenCitations bibliographic resource ID762111
P932PMC publication ID3277140
P698PubMed publication ID22307589
P5875ResearchGate publication ID221808109

P50authorRuedi AebersoldQ7377799
Andrej ŠaliQ4756078
Elizabeth VillaQ37391837
P2093author name stringFlorian Beck
Friedrich Förster
Pia Unverdorben
Wolfgang Baumeister
Keren Lasker
Stefan Bohn
Thomas Walzthoeni
P2860cites workJAMM: a metalloprotease-like zinc site in the proteasome and signalosomeQ21092836
Putting the pieces together: integrative modeling platform software for structure determination of macromolecular assembliesQ21145748
Identification of a functional docking site in the Rpn1 LRR domain for the UBA-UBL domain protein Ddi1Q21245310
A novel proteasome interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomesQ24304237
The crystal structure of the human Mov34 MPN domain reveals a metal-free dimerQ24309182
Docking of the proteasomal ATPases' carboxyl termini in the 20S proteasome's alpha ring opens the gate for substrate entryQ24674433
Structure of the Jab1/MPN Domain and Its Implications for Proteasome FunctionQ27642237
Proteasome subunit Rpn13 is a novel ubiquitin receptorQ27650664
Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interactionQ27650666
Structure and activity of the N-terminal substrate recognition domains in proteasomal ATPasesQ27655687
Structural Insights into the Regulatory Particle of the Proteasome from Methanocaldococcus jannaschiiQ27655690
Structure of the S5a:K48-Linked Diubiquitin Complex and Its Interactions with Rpn13Q27657027
Structures of asymmetric ClpX hexamers reveal nucleotide-dependent motions in a AAA+ protein-unfolding machineQ27658178
Structure of Proteasome Ubiquitin Receptor hRpn13 and Its Activation by the Scaffolding Protein hRpn2Q27661655
Structure of Rpn10 and Its Interactions with Polyubiquitin Chains and the Proteasome Subunit Rpn12Q27664179
The proteasomal subunit Rpn6 is a molecular clamp holding the core and regulatory subcomplexes togetherQ27676340
Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolutionQ27730197
Structure of 20S proteasome from yeast at 2.4 A resolutionQ27735081
The multiubiquitin-chain-binding protein Mcb1 is a component of the 26S proteasome in Saccharomyces cerevisiae and plays a nonessential, substrate-specific role in protein turnover.Q27929822
Proteasome subunit Rpn1 binds ubiquitin-like protein domainsQ27930136
Rpn9 is required for efficient assembly of the yeast 26S proteasomeQ27930434
An atomic model AAA-ATPase/20S core particle sub-complex of the 26S proteasomeQ37407311
PCI complexes: Beyond the proteasome, CSN, and eIF3 Troika.Q37580456
Differential regulation of the PanA and PanB proteasome-activating nucleotidase and 20S proteasomal proteins of the haloarchaeon Haloferax volcaniiQ37596158
Visual proteomicsQ37796206
Structural features of the 26 S proteasome complexQ39405119
Heterohexameric ring arrangement of the eukaryotic proteasomal ATPases: implications for proteasome structure and assembly.Q40836221
Mechanism of substrate unfolding and translocation by the regulatory particle of the proteasome from Methanocaldococcus jannaschiiQ41297845
Subunit stoichiometry and three-dimensional arrangement in proteasomes from Thermoplasma acidophilumQ41522143
ATP binds to proteasomal ATPases in pairs with distinct functional effects, implying an ordered reaction cycleQ42156125
ATP-dependent steps in the binding of ubiquitin conjugates to the 26S proteasome that commit to degradationQ42600957
Inferential optimization for simultaneous fitting of multiple components into a CryoEM map of their assemblyQ43129602
Evolution of proteasomal ATPasesQ43616474
Interaction of the anaphase-promoting complex/cyclosome and proteasome protein complexes with multiubiquitin chain-binding proteinsQ44342716
The N-terminal coiled coil of the Rhodococcus erythropolis ARC AAA ATPase is neither necessary for oligomerization nor nucleotide hydrolysisQ47904859
A repetitive sequence in subunits of the 26S proteasome and 20S cyclosome (anaphase-promoting complex).Q48049123
Basic Medical Research Award. The ubiquitin systemQ48372080
20S proteasomes have the potential to keep substrates in store for continual degradation.Q50740999
What curves alpha-solenoids? Evidence for an alpha-helical toroid structure of Rpn1 and Rpn2 proteins of the 26 S proteasomeQ77070509
Structure of S5a bound to monoubiquitin provides a model for polyubiquitin recognitionQ81643532
Functional analysis of Rpn6p, a lid component of the 26 S proteasome, using temperature-sensitive rpn6 mutants of the yeast Saccharomyces cerevisiaeQ27931530
RPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome: a negative feedback circuitQ27933746
Physical association of ubiquitin ligases and the 26S proteasomeQ27935257
A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3.Q27936509
Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasomeQ27937927
A cryptic protease couples deubiquitination and degradation by the proteasomeQ27938068
Global landscape of protein complexes in the yeast Saccharomyces cerevisiaeQ27938796
The molecular architecture of the nuclear pore complexQ27940363
Swinging arms and swinging domains in multifunctional enzymes: catalytic machines for multistep reactionsQ28145029
An asymmetric interface between the regulatory and core particles of the proteasomeQ28251784
Localization of the proteasomal ubiquitin receptors Rpn10 and Rpn13 by electron cryomicroscopyQ28256624
Dissection of the assembly pathway of the proteasome lid in Saccharomyces cerevisiaeQ28282533
Recognition and processing of ubiquitin-protein conjugates by the proteasomeQ29547616
A 26 S protease subunit that binds ubiquitin conjugatesQ29614362
The proteasome: paradigm of a self-compartmentalizing proteaseQ29615187
Flexible fitting of atomic structures into electron microscopy maps using molecular dynamicsQ29616808
Winged helix proteinsQ29617630
The 26S proteasome: a molecular machine designed for controlled proteolysisQ29619692
Probing native protein structures by chemical cross-linking, mass spectrometry, and bioinformaticsQ30387550
Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolutionQ30497623
Integrating diverse data for structure determination of macromolecular assembliesQ31148487
Structural organization of the 19S proteasome lid: insights from MS of intact complexes.Q33251840
Integrative structure modeling of macromolecular assemblies from proteomics dataQ33589651
Toward an integrated structural model of the 26S proteasomeQ34121912
Defining the geometry of the two-component proteasome degronQ34161503
Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1.Q34556881
Determining the architectures of macromolecular assembliesQ34719614
The eIF3c/NIP1 PCI domain interacts with RNA and RACK1/ASC1 and promotes assembly of translation preinitiation complexesQ35860658
The proteasome: a utility tool for transcription?Q36406913
The proteasome: overview of structure and functionsQ36472495
Inhibition of the 26 S proteasome by polyubiquitin chains synthesized to have defined lengthsQ36882353
Electron microscopic evidence in support of alpha-solenoid models of proteasomal subunits Rpn1 and Rpn2.Q37166178
Insights into the molecular architecture of the 26S proteasomeQ37274386
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)1380-7
P577publication date2012-01-31
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleMolecular architecture of the 26S proteasome holocomplex determined by an integrative approach
P478volume109

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