Nucleotide-dependent switch in proteasome assembly mediated by the Nas6 chaperone

scientific article published on 30 January 2017

Nucleotide-dependent switch in proteasome assembly mediated by the Nas6 chaperone is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1073/PNAS.1612922114
P932PMC publication ID5321026
P698PubMed publication ID28137839

P2093author name stringGeng Tian
Daniel Finley
Soyeon Park
Vladyslava Sokolova
Frances Li
Deanna Langager
P2860cites workSubcellular localization, stoichiometry, and protein levels of 26 S proteasome subunits in yeastQ22010425
Increased proteasome activity in human embryonic stem cells is regulated by PSMD11Q24298544
Assembly pathway of the Mammalian proteasome base subcomplex is mediated by multiple specific chaperonesQ24316277
Chaperone-mediated pathway of proteasome regulatory particle assemblyQ24321620
Mechanism of gate opening in the 20S proteasome by the proteasomal ATPasesQ24564109
Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasomeQ24567788
Docking of the proteasomal ATPases' carboxyl termini in the 20S proteasome's alpha ring opens the gate for substrate entryQ24674433
A gated channel into the proteasome core particleQ27627907
Structural basis for the recognition between the regulatory particles Nas6 and Rpt3 of the yeast 26S proteasomeQ27645374
The proteasomal subunit Rpn6 is a molecular clamp holding the core and regulatory subcomplexes togetherQ27676340
Reconfiguration of the proteasome during chaperone-mediated assemblyQ27677979
Dual functions of the Hsm3 protein in chaperoning and scaffolding regulatory particle subunits during the proteasome assemblyQ27678263
Formation of an intricate helical bundle dictates the assembly of the 26S proteasome lidQ27685325
Structural basis for proteasome formation controlled by an assembly chaperone nas2Q27689676
Global analysis of protein expression in yeastQ27860658
UCSF Chimera--a visualization system for exploratory research and analysisQ27860666
Hexameric assembly of the proteasomal ATPases is templated through their C terminiQ27931123
An inducible chaperone adapts proteasome assembly to stressQ27933155
Multiple proteasome-interacting proteins assist the assembly of the yeast 19S regulatory particleQ27936642
Structural defects in the regulatory particle-core particle interface of the proteasome induce a novel proteasome stress responseQ27938348
Hsm3/S5b participates in the assembly pathway of the 19S regulatory particle of the proteasomeQ27938858
The catalytic activity of Ubp6 enhances maturation of the proteasomal regulatory particleQ27938889
Multiple assembly chaperones govern biogenesis of the proteasome regulatory particle baseQ27939675
An asymmetric interface between the regulatory and core particles of the proteasomeQ28251784
Incorporation of the Rpn12 subunit couples completion of proteasome regulatory particle lid assembly to lid-base joiningQ28256050
Complete subunit architecture of the proteasome regulatory particleQ28257212
Molecular architecture of the 26S proteasome holocomplex determined by an integrative approachQ28259014
Conformational switching of the 26S proteasome enables substrate degradationQ28292908
The C Terminus of Rpt3, an ATPase Subunit of PA700 (19 S) Regulatory Complex, Is Essential for 26 S Proteasome Assembly but Not for ActivationQ28295352
The yeast polyubiquitin gene is essential for resistance to high temperatures, starvation, and other stressesQ29616169
The 1.9 A structure of a proteasome-11S activator complex and implications for proteasome-PAN/PA700 interactions.Q33987362
Structure of the 26S proteasome with ATP-γS bound provides insights into the mechanism of nucleotide-dependent substrate translocationQ34339520
C termini of proteasomal ATPases play nonequivalent roles in cellular assembly of mammalian 26 S proteasomeQ35128239
Loss of Rpt5 protein interactions with the core particle and Nas2 protein causes the formation of faulty proteasomes that are inhibited by Ecm29 protein.Q35378632
A Single α Helix Drives Extensive Remodeling of the Proteasome Lid and Completion of Regulatory Particle AssemblyQ36146766
Structure of an endogenous yeast 26S proteasome reveals two major conformational statesQ36684717
Subcomplexes of PA700, the 19 S regulator of the 26 S proteasome, reveal relative roles of AAA subunits in 26 S proteasome assembly and activation and ATPase activityQ37375673
Reconstitution of the 26S proteasome reveals functional asymmetries in its AAA+ unfoldaseQ37406494
The intrinsically disordered Sem1 protein functions as a molecular tether during proteasome lid biogenesis.Q37626715
Structural biology of the proteasomeQ38081952
Stable incorporation of ATPase subunits into 19 S regulatory particle of human proteasome requires nucleotide binding and C-terminal tailsQ38466156
Proteasome Activation is Mediated via a Functional Switch of the Rpt6 C-terminal Tail Following Chaperone-dependent Assembly.Q40451741
Heterohexameric ring arrangement of the eukaryotic proteasomal ATPases: implications for proteasome structure and assembly.Q40836221
Molecular model of the human 26S proteasomeQ41613713
Time-resolved measurements of intracellular ATP in the yeast Saccharomyces cerevisiae using a new type of nanobiosensorQ41713897
Ubiquitin ligase Hul5 is required for fragment-specific substrate degradation in endoplasmic reticulum-associated degradationQ46626985
Purification of proteasomes, proteasome subcomplexes, and proteasome-associated proteins from budding yeastQ81786895
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectmolecular chaperonesQ422496
P304page(s)1548-1553
P577publication date2017-01-30
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleNucleotide-dependent switch in proteasome assembly mediated by the Nas6 chaperone
P478volume114

Reverse relations

cites work (P2860)
Q61450205An Allosteric Interaction Network Promotes Conformation State-Dependent Eviction of the Nas6 Assembly Chaperone from Nascent 26S Proteasomes
Q40130408Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Q90078103Identification of ubiquitin-proteasome system components affecting the degradation of the transcription factor Pap1
Q91643887Native Gel Approaches in Studying Proteasome Assembly and Chaperones
Q39352782Proteasome Structure and Assembly
Q90673658Regulation of proteasome assembly and activity in health and disease
Q48092080Sophisticated lessons from simple organisms: appreciating the value of curiosity-driven research
Q95650650The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges
Q91983592Two alternative mechanisms regulate the onset of chaperone-mediated assembly of the proteasomal ATPases
Q90365039Ubiquitin-dependent switch during assembly of the proteasomal ATPases mediated by Not4 ubiquitin ligase

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