scholarly article | Q13442814 |
P2093 | author name string | Xiang Chen | |
Daniel Finley | |||
Kylie J Walters | |||
P2860 | cites work | In vitro assembly and recognition of Lys-63 polyubiquitin chains | Q43615489 |
ATP-dependent proteases degrade their substrates by processively unraveling them from the degradation signal | Q43681662 | ||
ATP hydrolysis by the proteasome regulatory complex PAN serves multiple functions in protein degradation | Q44283109 | ||
An unstructured initiation site is required for efficient proteasome-mediated degradation | Q45018402 | ||
The size of the proteasomal substrate determines whether its degradation will be mediated by mono- or polyubiquitylation | Q46223379 | ||
Ubiquitin ligase Hul5 is required for fragment-specific substrate degradation in endoplasmic reticulum-associated degradation | Q46626985 | ||
RPN-6 determines C. elegans longevity under proteotoxic stress conditions | Q46942610 | ||
Proteasomes. A molecular census of 26S proteasomes in intact neurons | Q48364209 | ||
Interaction of NUB1 with the proteasome subunit S5a. | Q50336228 | ||
The N-terminal unstructured domain of yeast ODC functions as a transplantable and replaceable ubiquitin-independent degron. | Q52607726 | ||
FAT10 and NUB1L bind to the VWA domain of Rpn10 and Rpn1 to enable proteasome-mediated proteolysis. | Q53178691 | ||
A ubiquitin stress response induces altered proteasome composition. | Q55043910 | ||
A conserved processing mechanism regulates the activity of transcription factors Cubitus interruptus and NF-κB | Q57851826 | ||
Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology | Q58215681 | ||
A series of ubiquitin binding factors connects CDC48/p97 to substrate multiubiquitylation and proteasomal targeting | Q81277350 | ||
Structure of S5a bound to monoubiquitin provides a model for polyubiquitin recognition | Q81643532 | ||
Modification by single ubiquitin moieties rather than polyubiquitination is sufficient for proteasomal processing of the p105 NF-κB precursor | Q82863691 | ||
Structural plasticity allows UCH37 to be primed by RPN13 or locked down by INO80G | Q86881857 | ||
Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction | Q27650666 | ||
Structure and activity of the N-terminal substrate recognition domains in proteasomal ATPases | Q27655687 | ||
Structural Insights into the Regulatory Particle of the Proteasome from Methanocaldococcus jannaschii | Q27655690 | ||
Structure of the S5a:K48-Linked Diubiquitin Complex and Its Interactions with Rpn13 | Q27657027 | ||
Structure of Proteasome Ubiquitin Receptor hRpn13 and Its Activation by the Scaffolding Protein hRpn2 | Q27661655 | ||
The proteasomal subunit Rpn6 is a molecular clamp holding the core and regulatory subcomplexes together | Q27676340 | ||
Reconfiguration of the proteasome during chaperone-mediated assembly | Q27677979 | ||
Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11 | Q27681666 | ||
Formation of an intricate helical bundle dictates the assembly of the 26S proteasome lid | Q27685325 | ||
Structure of the Rpn11-Rpn8 dimer reveals mechanisms of substrate deubiquitination during proteasomal degradation | Q27688973 | ||
Molecular architecture and assembly of the eukaryotic proteasome | Q27693890 | ||
Structure of 20S proteasome from yeast at 2.4 A resolution | Q27735081 | ||
Proteasome subunit Rpn1 binds ubiquitin-like protein domains | Q27930136 | ||
Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48(UFD1/NPL4), a ubiquitin-selective chaperone | Q27930650 | ||
Multiple associated proteins regulate proteasome structure and function | Q27931244 | ||
Blm10 protein promotes proteasomal substrate turnover by an active gating mechanism | Q27931319 | ||
Multiple interactions of rad23 suggest a mechanism for ubiquitylated substrate delivery important in proteolysis | Q27931879 | ||
Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation. | Q27932109 | ||
Ubiquitin chains are remodeled at the proteasome by opposing ubiquitin ligase and deubiquitinating activities. | Q27933653 | ||
RPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome: a negative feedback circuit | Q27933746 | ||
Acetylation-mediated proteasomal degradation of core histones during DNA repair and spermatogenesis | Q27933881 | ||
UBA domains of DNA damage-inducible proteins interact with ubiquitin | Q27935487 | ||
A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3. | Q27936509 | ||
Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome | Q27937064 | ||
Lysine 63-linked polyubiquitin chain may serve as a targeting signal for the 26S proteasome | Q27937521 | ||
Activation of a membrane-bound transcription factor by regulated ubiquitin/proteasome-dependent processing. | Q27937925 | ||
Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome | Q27937927 | ||
A cryptic protease couples deubiquitination and degradation by the proteasome | Q27938068 | ||
Structural defects in the regulatory particle-core particle interface of the proteasome induce a novel proteasome stress response | Q27938348 | ||
Additive loss-of-function proteasome subunit mutations in CANDLE/PRAAS patients promote type I IFN production | Q28114794 | ||
Regulation of CD8+ T cell development by thymus-specific proteasomes | Q28116400 | ||
Hybrid proteasomes. Induction by interferon-gamma and contribution to ATP-dependent proteolysis | Q28143710 | ||
Autoregulation of the 26S proteasome by in situ ubiquitination | Q28238443 | ||
Interaction of hHR23 with S5a. The ubiquitin-like domain of hHR23 mediates interaction with S5a subunit of 26 S proteasome | Q22010540 | ||
Autoubiquitination of the 26S proteasome on Rpn13 regulates breakdown of ubiquitin conjugates | Q24297402 | ||
Increased proteasome activity in human embryonic stem cells is regulated by PSMD11 | Q24298544 | ||
The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome | Q24302180 | ||
A novel proteasome interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomes | Q24304237 | ||
Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex | Q24313604 | ||
hRpn13/ADRM1/GP110 is a novel proteasome subunit that binds the deubiquitinating enzyme, UCH37 | Q24321826 | ||
Proteasome activator PA28gamma-dependent nuclear retention and degradation of hepatitis C virus core protein | Q24322067 | ||
Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex | Q24323042 | ||
UBLCP1 is a 26S proteasome phosphatase that regulates nuclear proteasome activity | Q24338712 | ||
Ubiquitin-associated (UBA) domains in Rad23 bind ubiquitin and promote inhibition of multi-ubiquitin chain assembly | Q24522596 | ||
Recognition of the polyubiquitin proteolytic signal | Q24530006 | ||
Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome | Q24567788 | ||
Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia | Q24600027 | ||
Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes? | Q24617857 | ||
Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation | Q24643067 | ||
Docking of the proteasomal ATPases' carboxyl termini in the 20S proteasome's alpha ring opens the gate for substrate entry | Q24674433 | ||
mTORC1 signaling activates NRF1 to increase cellular proteasome levels | Q27012468 | ||
Specific SKN-1/Nrf stress responses to perturbations in translation elongation and proteasome activity | Q27339698 | ||
A gated channel into the proteasome core particle | Q27627907 | ||
Structural basis for the activation of 20S proteasomes by 11S regulators | Q27628418 | ||
Structural studies of the interaction between ubiquitin family proteins and proteasome subunit S5a | Q27637621 | ||
Proteasome subunit Rpn13 is a novel ubiquitin receptor | Q27650664 | ||
Regulation of the 26S proteasome complex during oxidative stress | Q35120069 | ||
Structural basis for the activation and inhibition of the UCH37 deubiquitylase | Q35163646 | ||
Loss of Rpt5 protein interactions with the core particle and Nas2 protein causes the formation of faulty proteasomes that are inhibited by Ecm29 protein. | Q35378632 | ||
A three-part signal governs differential processing of Gli1 and Gli3 proteins by the proteasome | Q35604264 | ||
Substrate degradation by the proteasome: a single-molecule kinetic analysis | Q35670301 | ||
N-Terminal Coiled-Coil Structure of ATPase Subunits of 26S Proteasome Is Crucial for Proteasome Function | Q35712222 | ||
Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated Proteins and Cellular Homeostasis. | Q35723276 | ||
APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1 | Q35754866 | ||
Structural characterization of the interaction of Ubp6 with the 26S proteasome | Q35865605 | ||
Functional asymmetries of proteasome translocase pore | Q36002883 | ||
Ubp6 deubiquitinase controls conformational dynamics and substrate degradation of the 26S proteasome. | Q36029605 | ||
Identification and proteomic analysis of distinct UBE3A/E6AP protein complexes. | Q36210923 | ||
Development of proteasome inhibitors as research tools and cancer drugs | Q36389262 | ||
The ATP costs and time required to degrade ubiquitinated proteins by the 26 S proteasome. | Q37213960 | ||
The proteasome-associated protein Ecm29 inhibits proteasomal ATPase activity and in vivo protein degradation by the proteasome | Q37226121 | ||
The E3 ubiquitin ligase UBE3C enhances proteasome processivity by ubiquitinating partially proteolyzed substrates. | Q37348923 | ||
Reconstitution of the 26S proteasome reveals functional asymmetries in its AAA+ unfoldase | Q37406494 | ||
The lysine 48 and lysine 63 ubiquitin conjugates are processed differently by the 26 s proteasome | Q37467606 | ||
Marching to the beat of the ring: polypeptide translocation by AAA+ proteases. | Q37625067 | ||
The intrinsically disordered Sem1 protein functions as a molecular tether during proteasome lid biogenesis. | Q37626715 | ||
Proteasomes associated with the Blm10 activator protein antagonize mitochondrial fission through degradation of the fission protein Dnm1. | Q37727657 | ||
Assembly and function of the proteasome | Q37986626 | ||
Inhibitors for the immuno- and constitutive proteasome: current and future trends in drug development | Q38019864 | ||
Atypical ubiquitylation - the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages. | Q38028343 | ||
FAT10ylation as a signal for proteasomal degradation | Q38075383 | ||
Structural biology of the proteasome | Q38081952 | ||
Assembly of the 20S proteasome. | Q38090856 | ||
The mechanism for molecular assembly of the proteasome | Q38154406 | ||
The unique functions of tissue-specific proteasomes | Q38167099 | ||
Catching a DUB in the act: novel ubiquitin-based active site directed probes | Q38280690 | ||
Structural disorder and its role in proteasomal degradation | Q38557562 | ||
Reversible 26S proteasome disassembly upon mitochondrial stress. | Q38992225 | ||
Ubiquitin-independent degradation of cell-cycle inhibitors by the REGgamma proteasome | Q40115986 | ||
Ubiquitin- and ATP-independent proteolytic turnover of p21 by the REGgamma-proteasome pathway | Q40115992 | ||
Proteasome Activation is Mediated via a Functional Switch of the Rpt6 C-terminal Tail Following Chaperone-dependent Assembly. | Q40451741 | ||
Mechanism of UCH-L5 activation and inhibition by DEUBAD domains in RPN13 and INO80G. | Q41375336 | ||
Localization of the regulatory particle subunit Sem1 in the 26S proteasome | Q41611000 | ||
Molecular model of the human 26S proteasome | Q41613713 | ||
Coordinated gripping of substrate by subunits of a AAA+ proteolytic machine | Q41876436 | ||
Ubiquitinated proteins activate the proteasome by binding to Usp14/Ubp6, which causes 20S gate opening | Q41915219 | ||
Identification of the Cdc48•20S proteasome as an ancient AAA+ proteolytic machine. | Q41953180 | ||
Sequence composition of disordered regions fine-tunes protein half-life | Q42010327 | ||
Hul5 HECT ubiquitin ligase plays a major role in the ubiquitylation and turnover of cytosolic misfolded proteins | Q42069478 | ||
An ALS disease mutation in Cdc48/p97 impairs 20S proteasome binding and proteolytic communication | Q42269965 | ||
Dissection of Axial-Pore Loop Function during Unfolding and Translocation by a AAA+ Proteolytic Machine | Q42530780 | ||
ATP-dependent steps in the binding of ubiquitin conjugates to the 26S proteasome that commit to degradation | Q42600957 | ||
The ubiquitin ligase Hul5 promotes proteasomal processivity | Q42924551 | ||
Together, Rpn10 and Dsk2 can serve as a polyubiquitin chain-length sensor | Q42936102 | ||
Dss1 is a 26S proteasome ubiquitin receptor | Q43006495 | ||
Proteasome-mediated processing of Nrf1 is essential for coordinate induction of all proteasome subunits and p97 | Q28243388 | ||
An asymmetric interface between the regulatory and core particles of the proteasome | Q28251784 | ||
Complete subunit architecture of the proteasome regulatory particle | Q28257212 | ||
Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach | Q28259014 | ||
Control of p97 function by cofactor binding | Q28266780 | ||
Transcription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cells | Q28279454 | ||
Conformational switching of the 26S proteasome enables substrate degradation | Q28292908 | ||
Proteasomal Degradation Is Transcriptionally Controlled by TCF11 via an ERAD-Dependent Feedback Loop | Q28295179 | ||
Editing of ubiquitin conjugates by an isopeptidase in the 26S proteasome | Q28303702 | ||
p97-dependent retrotranslocation and proteolytic processing govern formation of active Nrf1 upon proteasome inhibition | Q28306282 | ||
Evolution of proteasome regulators in eukaryotes | Q28334391 | ||
Regulation of proteasome activity in health and disease | Q28392708 | ||
Phosphorylation of Rpt6 regulates synaptic strength in hippocampal neurons | Q28579831 | ||
Autophagic Degradation of the 26S Proteasome Is Mediated by the Dual ATG8/Ubiquitin Receptor RPN10 in Arabidopsis | Q28830597 | ||
Recognition and processing of ubiquitin-protein conjugates by the proteasome | Q29547616 | ||
A 26 S protease subunit that binds ubiquitin conjugates | Q29614362 | ||
Enhancement of proteasome activity by a small-molecule inhibitor of USP14 | Q29616735 | ||
The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B | Q29618194 | ||
Global unfolding of a substrate protein by the Hsp100 chaperone ClpA. | Q30322959 | ||
Near-atomic resolution structural model of the yeast 26S proteasome. | Q30524942 | ||
Enhanced protein degradation by branched ubiquitin chains. | Q33637926 | ||
Rad23 escapes degradation because it lacks a proteasome initiation region | Q33801171 | ||
PA28αβ: the enigmatic magic ring of the proteasome? | Q33912635 | ||
Productive RUPture: activation of transcription factors by proteasomal processing. | Q33983417 | ||
Delivery of ubiquitinated substrates to protein-unfolding machines | Q33989072 | ||
Proteasome regulation by ADP-ribosylation | Q34036523 | ||
Defining the geometry of the two-component proteasome degron | Q34161503 | ||
AAA+ proteases: ATP-fueled machines of protein destruction | Q34176192 | ||
Structure of the 26S proteasome with ATP-γS bound provides insights into the mechanism of nucleotide-dependent substrate translocation | Q34339520 | ||
Intrinsically disordered segments affect protein half-life in the cell and during evolution | Q34438593 | ||
Pri sORF peptides induce selective proteasome-mediated protein processing | Q34494721 | ||
Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1. | Q34556881 | ||
Ubiquitin-aldehyde: a general inhibitor of ubiquitin-recycling processes | Q34607942 | ||
Proteasomal degradation of Sfp1 contributes to the repression of ribosome biogenesis during starvation and is mediated by the proteasome activator Blm10. | Q34611628 | ||
Ubiquitin depletion as a key mediator of toxicity by translational inhibitors | Q34986792 | ||
P433 | issue | 1 | |
P1104 | number of pages | 17 | |
P304 | page(s) | 77-93 | |
P577 | publication date | 2015-11-28 | |
P1433 | published in | Trends in Biochemical Sciences | Q1565711 |
P1476 | title | Gates, Channels, and Switches: Elements of the Proteasome Machine | |
P478 | volume | 41 |
Q90235126 | (Un)folding mechanisms of adaptation to ER stress: lessons from aneuploidy |
Q64096816 | A Practical Review of Proteasome Pharmacology |
Q52653236 | A common mechanism of proteasome impairment by neurodegenerative disease-associated oligomers. |
Q92005525 | Alterations in Organismal Physiology, Impaired Stress Resistance, and Accelerated Aging in Drosophila Flies Adapted to Multigenerational Proteome Instability |
Q90239219 | An Extended Conformation for K48 Ubiquitin Chains Revealed by the hRpn2:Rpn13:K48-Diubiquitin Structure |
Q41729079 | An assay for 26S proteasome activity based on fluorescence anisotropy measurements of dye-labeled protein substrates |
Q27720380 | An atomic structure of the human 26S proteasome |
Q58782566 | BALCONY: an R package for MSA and functional compartments of protein variability analysis |
Q41431696 | Bimodal antagonism of PKA signalling by ARHGAP36. |
Q55363518 | Biological and Pathological Implications of an Alternative ATP-Powered Proteasomal Assembly With Cdc48 and the 20S Peptidase. |
Q92651130 | Biology and Biochemistry of Bacterial Proteasomes |
Q37076872 | Characterization of Dynamic UbR-Proteasome Subcomplexes by In vivo Cross-linking (X) Assisted Bimolecular Tandem Affinity Purification (XBAP) and Label-free Quantitation |
Q37078653 | Conserved Sequence Preferences Contribute to Substrate Recognition by the Proteasome |
Q59060928 | Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome |
Q48265884 | Deubiquitylating enzymes and drug discovery: emerging opportunities. |
Q92340026 | Diverse fate of ubiquitin chain moieties: The proximal is degraded with the target, and the distal protects the proximal from removal and recycles |
Q47137426 | Electrostatic Map Of Proteasome α-Rings Encodes The Design of Allosteric Porphyrin-Based Inhibitors Able To Affect 20S Conformation By Cooperative Binding. |
Q92608381 | Engineered disulfide crosslinking to measure conformational changes in the 26S proteasome |
Q90691676 | Expanded Coverage of the 26S Proteasome Conformational Landscape Reveals Mechanisms of Peptidase Gating |
Q89865089 | Exploring long-range cooperativity in the 20S proteasome core particle from Thermoplasma acidophilum using methyl-TROSY-based NMR |
Q92133366 | Gid10 as an alternative N-recognin of the Pro/N-degron pathway |
Q37469674 | Gyre and gimble in the proteasome |
Q39010593 | High-resolution cryo-EM structure of the proteasome in complex with ADP-AlFx |
Q27468807 | How Polyomaviruses Exploit the ERAD Machinery to Cause Infection |
Q92825683 | How the 26S Proteasome Degrades Ubiquitinated Proteins in the Cell |
Q49344570 | In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. |
Q28554929 | Insecticidal Activity of Melaleuca alternifolia Essential Oil and RNA-Seq Analysis of Sitophilus zeamais Transcriptome in Response to Oil Fumigation |
Q50421272 | MAPK signaling couples SCF-mediated degradation of translational regulators to oocyte meiotic progression. |
Q39094217 | Mass Spectrometry: A Technique of Many Faces |
Q92608420 | Monitoring stress-induced autophagic engulfment and degradation of the 26S proteasome in mammalian cells |
Q37181867 | Monoubiquitination in proteasomal degradation |
Q39298346 | Monoubiquitination joins polyubiquitination as an esteemed proteasomal targeting signal |
Q64990528 | Mutational and Combinatorial Control of Self-Assembling and Disassembling of Human Proteasome α Subunits. |
Q39605561 | Mycobacterium tuberculosis proteasomal ATPase Mpa has a β-grasp domain that hinders docking with the proteasome core protease. |
Q51144722 | New insight into the mechanism underlying the silk gland biological process by knocking out fibroin heavy chain in the silkworm. |
Q55559653 | Oncogenic addiction to high 26S proteasome level. |
Q36675188 | Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation |
Q56753804 | PIP30/FAM192A is a novel regulator of the nuclear proteasome activator PA28γ |
Q37006187 | Phosphorylation of the C-terminal tail of proteasome subunit α7 is required for binding of the proteasome quality control factor Ecm29. |
Q59358545 | Pleiotropic roles of the ubiquitin-proteasome system during viral propagation |
Q52326726 | Polylysine is a Proteostasis Network-Engaging Structural Determinant. |
Q47583613 | Probing the cooperativity of Thermoplasma acidophilum proteasome core particle gating by NMR spectroscopy |
Q92157489 | Proteasome Activation as a New Therapeutic Approach To Target Proteotoxic Disorders |
Q92454652 | Proteasome Activation to Combat Proteotoxicity |
Q89598452 | Proteasome Inhibitors: Harnessing Proteostasis to Combat Disease |
Q90009190 | Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing mitochondrial fusion or autophagy |
Q39201929 | Proteasome expression and activity in cancer and cancer stem cells |
Q50134103 | Proteasome substrate capture and gate opening by the accessory factor PafE from Mycobacterium tuberculosis |
Q91329955 | Proteasome subunit RPT2a promotes PTGS through repressing RNA quality control in Arabidopsis |
Q39422863 | Protein Degradation Systems as Antimalarial Therapeutic Targets |
Q53207197 | Ramping up degradation for proliferation. |
Q92605248 | Reduced chronic restraint stress in mice overexpressing hyperactive proteasomes in the forebrain |
Q47744329 | Regulating protein breakdown through proteasome phosphorylation |
Q57804729 | Revealing the cellular degradome by mass spectrometry analysis of proteasome-cleaved peptides |
Q37712428 | Reversible phosphorylation of the 26S proteasome. |
Q35935216 | Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasome |
Q47141859 | Small Molecule Enhancement of 20S Proteasome Activity Targets Intrinsically Disordered Proteins |
Q89087470 | Small Molecule Modulation of Proteasome Assembly |
Q83225722 | Specific lid-base contacts in the 26s proteasome control the conformational switching required for substrate degradation |
Q51016592 | Structural Insight into Ubiquitin-Like Protein Recognition and Oligomeric States of JAMM/MPN+ Proteases. |
Q37469477 | Structural basis for dynamic regulation of the human 26S proteasome |
Q91826930 | Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex |
Q47247682 | Structural insights on the dynamics of proteasome formation |
Q53831231 | Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome. |
Q52322457 | Structure and Function of the 26S Proteasome. |
Q90207565 | Structure of E3 ligase E6AP with a proteasome-binding site provided by substrate receptor hRpn10 |
Q36684717 | Structure of an endogenous yeast 26S proteasome reveals two major conformational states |
Q61727849 | Structure of hRpn10 Bound to UBQLN2 UBL Illustrates Basis for Complementarity between Shuttle Factors and Substrates at the Proteasome |
Q33862782 | Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets |
Q37102327 | Structure of the human 26S proteasome at a resolution of 3.9 Å. |
Q42382149 | Structures of Rpn1 T1:Rad23 and hRpn13:hPLIC2 Reveal Distinct Binding Mechanisms between Substrate Receptors and Shuttle Factors of the Proteasome |
Q52341015 | TRIM11 activates the proteasome and promotes overall protein degradation by regulating USP14. |
Q100946120 | Tagging the proteasome active site β5 causes tag specific phenotypes in yeast |
Q64977661 | Targeting Protein Quality Control Mechanisms by Natural Products to Promote Healthy Ageing. |
Q64101352 | The HslV Protease from and Its Activation by C-terminal HslU Peptides |
Q39318404 | The Logic of the 26S Proteasome |
Q36884720 | The Proteasome Ubiquitin Receptor hRpn13 and Its Interacting Deubiquitinating Enzyme Uch37 Are Required for Proper Cell Cycle Progression |
Q47745372 | The Ubiquitin Code in the Ubiquitin-Proteasome System and Autophagy |
Q26738549 | The life cycle of the 26S proteasome: from birth, through regulation and function, and onto its death |
Q92932075 | The proteasome 19S cap and its ubiquitin receptors provide a versatile recognition platform for substrates |
Q95650650 | The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges |
Q34535073 | The ubiquitin-proteasome system and autophagy: Coordinated and independent activities |
Q91624576 | The ubiquitin-proteasome system in kidney physiology and disease |
Q52718493 | Thermal proteome profiling of breast cancer cells reveals proteasomal activation by CDK4/6 inhibitor palbociclib. |
Q93379935 | UBL domain of Usp14 and other proteins stimulates proteasome activities and protein degradation in cells |
Q36834923 | USP14 deubiquitinates proteasome-bound substrates that are ubiquitinated at multiple sites |
Q39257016 | Ubiquitin C-terminal hydrolase-L1 (UCH-L1) as a therapeutic and diagnostic target in neurodegeneration, neurotrauma and neuro-injuries |
Q39077452 | Ubiquitin recognition by the proteasome |
Q42782877 | Ubiquitinated proteins promote the association of proteasomes with the deubiquitinating enzyme Usp14 and the ubiquitin ligase Ube3c |
Q57292282 | ZFAND5/ZNF216 is an activator of the 26S proteasome that stimulates overall protein degradation |
Q37451072 | p62- and ubiquitin-dependent stress-induced autophagy of the mammalian 26S proteasome. |
Search more.