Structural basis for dynamic regulation of the human 26S proteasome

scientific article published on 21 October 2016

Structural basis for dynamic regulation of the human 26S proteasome is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1073/PNAS.1614614113
P8608Fatcat IDrelease_zogqmwdi2bbftpzeuyi4ldne7m
P932PMC publication ID5135334
P698PubMed publication ID27791164

P50authorYoudong MaoQ57037375
P2093author name stringMarc W Kirschner
Zhou Yu
Byung-Hoon Lee
Ying Lu
Qi Ouyang
Jiayi Wu
Shuobing Chen
Daniel J Finley
Yong-Bei Ma
P2860cites workMass spectrometric characterization of the affinity-purified human 26S proteasome complexQ24298353
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Structural basis for the activation of 20S proteasomes by 11S regulatorsQ27628418
Ubiquitinated proteins activate the proteasomal ATPases by binding to Usp14 or Uch37 homologsQ36685213
Structure of the human 26S proteasome at a resolution of 3.9 Å.Q37102327
Reconstitution of the 26S proteasome reveals functional asymmetries in its AAA+ unfoldaseQ37406494
Inhibitors for the immuno- and constitutive proteasome: current and future trends in drug developmentQ38019864
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Stable incorporation of ATPase subunits into 19 S regulatory particle of human proteasome requires nucleotide binding and C-terminal tailsQ38466156
Mechanism of substrate unfolding and translocation by the regulatory particle of the proteasome from Methanocaldococcus jannaschiiQ41297845
Molecular model of the human 26S proteasomeQ41613713
Coordinated gripping of substrate by subunits of a AAA+ proteolytic machineQ41876436
Disentangling conformational states of macromolecules in 3D-EM through likelihood optimization.Q54449974
Structure of S5a bound to monoubiquitin provides a model for polyubiquitin recognitionQ81643532
The structure of the mammalian 20S proteasome at 2.75 A resolutionQ27638997
Structural Insights into the Regulatory Particle of the Proteasome from Methanocaldococcus jannaschiiQ27655690
Structure of the S5a:K48-Linked Diubiquitin Complex and Its Interactions with Rpn13Q27657027
Structural Models for Interactions between the 20S Proteasome and Its PAN/19S ActivatorsQ27658058
Structures of asymmetric ClpX hexamers reveal nucleotide-dependent motions in a AAA+ protein-unfolding machineQ27658178
Structure of Rpn10 and Its Interactions with Polyubiquitin Chains and the Proteasome Subunit Rpn12Q27664179
Structural and functional characterization of Rpn12 identifies residues required for Rpn10 proteasome incorporationQ27671597
The proteasomal subunit Rpn6 is a molecular clamp holding the core and regulatory subcomplexes togetherQ27676340
The structure of the 26S proteasome subunit Rpn2 reveals its PC repeat domain as a closed toroid of two concentric α-helical ringsQ27677964
Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11Q27681666
Formation of an intricate helical bundle dictates the assembly of the 26S proteasome lidQ27685325
Structure of the Rpn11-Rpn8 dimer reveals mechanisms of substrate deubiquitination during proteasomal degradationQ27688973
Molecular architecture and assembly of the eukaryotic proteasomeQ27693890
Crystal structure of the human 20S proteasome in complex with carfilzomibQ27697584
An atomic structure of the human 26S proteasomeQ27720380
Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolutionQ27730197
Structure of 20S proteasome from yeast at 2.4 A resolutionQ27735081
AAA+ superfamily ATPases: common structure--diverse functionQ28208908
An asymmetric interface between the regulatory and core particles of the proteasomeQ28251784
Complete subunit architecture of the proteasome regulatory particleQ28257212
Molecular architecture of the 26S proteasome holocomplex determined by an integrative approachQ28259014
Conformational switching of the 26S proteasome enables substrate degradationQ28292908
Recognition and processing of ubiquitin-protein conjugates by the proteasomeQ29547616
HOLE: a program for the analysis of the pore dimensions of ion channel structural modelsQ29619250
Near-atomic resolution structural model of the yeast 26S proteasome.Q30524942
AAA+ proteases: ATP-fueled machines of protein destructionQ34176192
Structure of the 26S proteasome with ATP-γS bound provides insights into the mechanism of nucleotide-dependent substrate translocationQ34339520
The 'glutamate switch' provides a link between ATPase activity and ligand binding in AAA+ proteinsQ34851278
C termini of proteasomal ATPases play nonequivalent roles in cellular assembly of mammalian 26 S proteasomeQ35128239
A Bayesian view on cryo-EM structure determination.Q35859527
Gates, Channels, and Switches: Elements of the Proteasome MachineQ35862786
Functional asymmetries of proteasome translocase poreQ36002883
Atomic structure of the 26S proteasome lid reveals the mechanism of deubiquitinase inhibition.Q36568548
Structure of an endogenous yeast 26S proteasome reveals two major conformational statesQ36684717
P433issue46
P407language of work or nameEnglishQ1860
P304page(s)12991-12996
P577publication date2016-10-21
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleStructural basis for dynamic regulation of the human 26S proteasome
P478volume113

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