Structural Models for Interactions between the 20S Proteasome and Its PAN/19S Activators

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Structural Models for Interactions between the 20S Proteasome and Its PAN/19S Activators is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.C109.070425
P932PMC publication ID2804157
P698PubMed publication ID19889631

P50authorAnnie HerouxQ28324268
P2093author name stringHoward Robinson
David G Myszka
Christopher P Hill
Beth M Stadtmueller
Frank G Whitby
Katherine Ferrell
P2860cites workPA200, a nuclear proteasome activator involved in DNA repairQ24536971
Mechanism of gate opening in the 20S proteasome by the proteasomal ATPasesQ24564109
Docking of the proteasomal ATPases' carboxyl termini in the 20S proteasome's alpha ring opens the gate for substrate entryQ24674433
MolProbity: all-atom contacts and structure validation for proteins and nucleic acidsQ24684673
Structural basis for the activation of 20S proteasomes by 11S regulatorsQ27628418
The structure of the mammalian 20S proteasome at 2.75 A resolutionQ27638997
Investigations on the maturation and regulation of archaebacterial proteasomesQ27640607
Structure and activity of the N-terminal substrate recognition domains in proteasomal ATPasesQ27655687
Structural Insights into the Regulatory Particle of the Proteasome from Methanocaldococcus jannaschiiQ27655690
Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolutionQ27730197
Structure of 20S proteasome from yeast at 2.4 A resolutionQ27735081
Multiple associated proteins regulate proteasome structure and functionQ27931244
The regulatory particle of the Saccharomyces cerevisiae proteasome.Q27936746
Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasomeQ27937064
The HEAT repeat protein Blm10 regulates the yeast proteasome by capping the core particleQ27938094
Purification of an 11 S regulator of the multicatalytic proteaseQ28202111
The proteasomeQ33689946
An archaebacterial ATPase, homologous to ATPases in the eukaryotic 26 S proteasome, activates protein breakdown by 20 S proteasomesQ33873082
The 1.9 A structure of a proteasome-11S activator complex and implications for proteasome-PAN/PA700 interactions.Q33987362
ATP binding to PAN or the 26S ATPases causes association with the 20S proteasome, gate opening, and translocation of unfolded proteins.Q33991996
Distinct 19 S and 20 S subcomplexes of the 26 S proteasome and their distribution in the nucleus and the cytoplasmQ34060474
Structure of the Blm10-20 S proteasome complex by cryo-electron microscopy. Insights into the mechanism of activation of mature yeast proteasomes.Q34307472
Proteasome from Thermoplasma acidophilum: a threonine proteaseQ34309062
The proteasome: a supramolecular assembly designed for controlled proteolysisQ34545602
The axial channel of the 20S proteasome opens upon binding of the PA200 activatorQ34555139
Identification of an activation region in the proteasome activator REGalphaQ35972023
Mobilizing the proteolytic machine: cell biological roles of proteasome activators and inhibitorsQ36010873
The pore of activated 20S proteasomes has an ordered 7-fold symmetric conformationQ36065854
Functions of the proteasome: from protein degradation and immune surveillance to cancer therapyQ36703005
Structural and functional characterizations of the proteasome-activating protein PA26 from Trypanosoma bruceiQ41703202
ATP hydrolysis by the proteasome regulatory complex PAN serves multiple functions in protein degradationQ44283109
Identification, purification, and characterization of a high molecular weight, ATP-dependent activator (PA700) of the 20 S proteasome.Q47379441
Functional and structural characterization of the Methanosarcina mazei proteasome and PAN complexes.Q50730739
Purification and characterization of a multiprotein component of the Drosophila 26 S (1500 kDa) proteolytic complex.Q52545359
Multiple forms of the 20 S multicatalytic and the 26 S ubiquitin/ATP-dependent proteases from rabbit reticulocyte lysateQ54258141
Identification, purification, and characterization of a protein activator (PA28) of the 20 S proteasome (macropain)Q68127933
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
P304page(s)13-7
P577publication date2010-01-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleStructural Models for Interactions between the 20S Proteasome and Its PAN/19S Activators
P478volume285

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cites work (P2860)
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