Rpn1 and Rpn2 coordinate ubiquitin processing factors at proteasome

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Rpn1 and Rpn2 coordinate ubiquitin processing factors at proteasome is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M111.316323
P3181OpenCitations bibliographic resource ID2501571
P932PMC publication ID3340268
P698PubMed publication ID22318722

P50authorRina RosenzweigQ27925357
Michael H GlickmanQ63658957
David FushmanQ87987270
P2093author name stringDaoning Zhang
Vered Bronner
P2860cites workThe proteasome and the delicate balance between destruction and rescueQ21092835
Identification of a functional docking site in the Rpn1 LRR domain for the UBA-UBL domain protein Ddi1Q21245310
Cross-species divergence of the major recognition pathways of ubiquitylated substrates for ubiquitin/26S proteasome-mediated proteolysisQ24294410
A novel proteasome interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomesQ24304237
Relative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasomeQ24305134
The zinc finger of the CSN-associated deubiquitinating enzyme USP15 is essential to rescue the E3 ligase Rbx1Q24307443
cDNA cloning and functional analysis of the p97 subunit of the 26S proteasome, a polypeptide identical to the type-1 tumor-necrosis-factor-receptor-associated protein-2/55.11Q24318067
Efficient protection and isolation of ubiquitylated proteins using tandem ubiquitin-binding entitiesQ24320127
Chaperone-mediated pathway of proteasome regulatory particle assemblyQ24321620
Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehydeQ27640257
Crystal Structure of the HEAT Domain from the Pre-mRNA Processing Factor SymplekinQ27646447
Affinity Makes the Difference: Nonselective Interaction of the UBA Domain of Ubiquilin-1 with Monomeric Ubiquitin and Polyubiquitin ChainsQ27649753
Proteasome subunit Rpn13 is a novel ubiquitin receptorQ27650664
Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interactionQ27650666
Crystallographic structure of the tetratricopeptide repeat domain ofPlasmodium falciparumFKBP35 and its molecular interaction with Hsp90 C-terminal pentapeptideQ27657068
Structural Models for Interactions between the 20S Proteasome and Its PAN/19S ActivatorsQ27658058
Crystal structure of DNA-PKcs reveals a large open-ring cradle comprised of HEAT repeatsQ27658689
Crystal Structure of P58(IPK) TPR Fragment Reveals the Mechanism for its Molecular Chaperone Activity in UPRQ27660049
Structure of a Blm10 Complex Reveals Common Mechanisms for Proteasome Binding and Gate OpeningQ27660222
Structure of Proteasome Ubiquitin Receptor hRpn13 and Its Activation by the Scaffolding Protein hRpn2Q27661655
The Contribution of Entropy, Enthalpy, and Hydrophobic Desolvation to Cooperativity in Repeat-Protein FoldingQ27667256
Structure of the USP15 N-terminal domains: a β-hairpin mediates close association between the DUSP and UBL domainsQ27671804
Proteasome subunit Rpn1 binds ubiquitin-like protein domainsQ27930136
The C-terminal extension of the beta7 subunit and activator complexes stabilize nascent 20 S proteasomes and promote their maturationQ27930979
Multiple associated proteins regulate proteasome structure and functionQ27931244
Identification of ubiquitin-like protein-binding subunits of the 26S proteasomeQ27931789
Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation.Q27932109
Rad23 and Rpn10 serve as alternative ubiquitin receptors for the proteasomeQ27933278
Budding yeast Dsk2p is a polyubiquitin-binding protein that can interact with the proteasomeQ27934803
UBA domains of DNA damage-inducible proteins interact with ubiquitinQ27935487
Multiubiquitin chain receptors define a layer of substrate selectivity in the ubiquitin-proteasome systemQ27935666
The yeast SEN3 gene encodes a regulatory subunit of the 26S proteasome complex required for ubiquitin-dependent protein degradation in vivoQ27936053
A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3.Q27936509
Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasomeQ27937927
A cryptic protease couples deubiquitination and degradation by the proteasomeQ27938068
The bipartite nuclear localization sequence of Rpn2 is required for nuclear import of proteasomal base complexes via karyopherin alphabeta and proteasome functionsQ27939320
Complementary roles for Rpn11 and Ubp6 in deubiquitination and proteolysis by the proteasomeQ27939996
Diverse polyubiquitin interaction properties of ubiquitin-associated domainsQ46592679
Ddi1, a eukaryotic protein with the retroviral protease foldQ47184185
New HEAT-like repeat motifs in proteins regulating proteasome structure and functionQ47729238
The Arabidopsis 26S proteasome subunit RPN1a is required for optimal plant growth and stress responses.Q51930372
The UBA2 domain functions as an intrinsic stabilization signal that protects Rad23 from proteasomal degradation.Q52563832
Rpn10 protects the proteasome from Dsk2.Q53437009
To degrade or release: ubiquitin-chain remodelingQ57851806
The 20S Proteasome as an Assembly Platform for the 19S Regulatory ComplexQ64166848
Modulation of nuclear receptor interactions by ligands: kinetic analysis using surface plasmon resonanceQ71010169
Specific interactions between ATPase subunits of the 26 S proteaseQ73335066
What curves alpha-solenoids? Evidence for an alpha-helical toroid structure of Rpn1 and Rpn2 proteins of the 26 S proteasomeQ77070509
Ubiquitin binding proteins protect ubiquitin conjugates from disassemblyQ78862746
UBL/UBA ubiquitin receptor proteins bind a common tetraubiquitin chainQ82233807
Mapping subunit contacts in the regulatory complex of the 26 S proteasome. S2 and S5b form a tetramer with ATPase subunits S4 and S7Q28142118
Quaternary structure of the ATPase complex of human 26S proteasomes determined by chemical cross-linkingQ28189874
Targeting proteins for degradationQ28261886
Differential roles of the COOH termini of AAA subunits of PA700 (19 S regulator) in asymmetric assembly and activation of the 26 S proteasomeQ28294192
A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14Q28359750
An Unusual Hydrophobic Core Confers Extreme Flexibility to HEAT Repeat ProteinsQ29029185
Recognition and processing of ubiquitin-protein conjugates by the proteasomeQ29547616
Proteins containing the UBA domain are able to bind to multi-ubiquitin chainsQ29614360
Rad23 links DNA repair to the ubiquitin/proteasome pathwayQ29614361
Comparison of ARM and HEAT protein repeatsQ29616046
The yeast polyubiquitin gene is essential for resistance to high temperatures, starvation, and other stressesQ29616169
Ubiquitin-binding domainsQ29616461
PR65, the HEAT-repeat scaffold of phosphatase PP2A, is an elastic connector that links force and catalysisQ30493200
Highly sensitive detection of individual HEAT and ARM repeats with HHpred and COACHQ33506411
A protein-protein interaction map of the Caenorhabditis elegans 26S proteasomeQ33757687
Assembly, structure, and function of the 26S proteasome.Q33988314
Rad23 promotes the targeting of proteolytic substrates to the proteasomeQ34283029
Physiologically relevant and portable tandem ubiquitin-binding domain stabilizes polyubiquitylated proteinsQ34359170
The UBA domain: a sequence motif present in multiple enzyme classes of the ubiquitination pathwayQ34402796
Trimming of Ubiquitin Chains by Proteasome-associated Deubiquitinating EnzymesQ34994389
Transferring substrates to the 26S proteasome.Q35040957
Deubiquitinating enzymes are IN/(trinsic to proteasome function).Q35799696
Integral UBL domain proteins: a family of proteasome interacting proteins.Q35812455
The Ubp6 family of deubiquitinating enzymes contains a ubiquitin-like domain: SUb.Q36281573
Ubiquitin-binding proteins: similar, but different.Q36297836
Karyopherin flexibility in nucleocytoplasmic transportQ36432992
Proteasomes from structure to function: perspectives from ArchaeaQ36597934
Extraproteasomal Rpn10 restricts access of the polyubiquitin-binding protein Dsk2 to proteasome.Q37098025
Electron microscopic evidence in support of alpha-solenoid models of proteasomal subunits Rpn1 and Rpn2.Q37166178
Proteasome activator 200: the heat is on...Q37851267
Proteasomal AAA-ATPases: structure and function.Q37912396
Thioredoxin Txnl1/TRP32 is a redox-active cofactor of the 26 S proteasomeQ39863692
Insights into the domain and repeat architecture of target of rapamycinQ40090798
Binding of polyubiquitin chains to ubiquitin-associated (UBA) domains of HHR23A.Q40488188
The central unit within the 19S regulatory particle of the proteasomeQ40817421
Mechanism of substrate unfolding and translocation by the regulatory particle of the proteasome from Methanocaldococcus jannaschiiQ41297845
Ubiquitin-specific protease 4 is inhibited by its ubiquitin-like domainQ41861997
Ubiquitinated proteins activate the proteasome by binding to Usp14/Ubp6, which causes 20S gate openingQ41915219
C-terminal UBA domains protect ubiquitin receptors by preventing initiation of protein degradationQ42098390
PrDOS: prediction of disordered protein regions from amino acid sequenceQ42431942
ATP-dependent steps in the binding of ubiquitin conjugates to the 26S proteasome that commit to degradationQ42600957
Together, Rpn10 and Dsk2 can serve as a polyubiquitin chain-length sensorQ42936102
Interaction of the anaphase-promoting complex/cyclosome and proteasome protein complexes with multiubiquitin chain-binding proteinsQ44342716
P433issue18
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
ubiquitin-proteasome systemQ47175589
P1104number of pages13
P304page(s)14659-14671
P577publication date2012-02-08
P1433published inJournal of Biological ChemistryQ867727
P1476titleRpn1 and Rpn2 coordinate ubiquitin processing factors at proteasome
P478volume287

Reverse relations

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