| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2010PNAS..107.2467G |
| P356 | DOI | 10.1073/PNAS.0914073107 |
| P932 | PMC publication ID | 2823866 |
| P698 | PubMed publication ID | 20133745 |
| P5875 | ResearchGate publication ID | 41408597 |
| P50 | author | Martin Karplus | Q903471 |
| P2093 | author name string | Alison Grinthal | |
| Nancy Kleckner | |||
| Ivana Adamovic | |||
| Beth Weiner | |||
| P2860 | cites work | The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs | Q22001450 |
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| Active-site mutations impairing the catalytic function of the catalytic subunit of human protein phosphatase 2A permit baculovirus-mediated overexpression in insect cells | Q28367237 | ||
| Mammalian SGO2 appears at the inner centromere domain and redistributes depending on tension across centromeres during meiosis II and mitosis | Q28513034 | ||
| Comparison of ARM and HEAT protein repeats | Q29616046 | ||
| Stretching single talin rod molecules activates vinculin binding | Q29617762 | ||
| How cells get the right chromosomes | Q29618857 | ||
| Protein architecture of the human kinetochore microtubule attachment site | Q30436130 | ||
| Stepwise unfolding of ankyrin repeats in a single protein revealed by atomic force microscopy | Q30476820 | ||
| The micromachinery of mechanotransduction in hair cells | Q30481576 | ||
| The allosteric role of the Ca2+ switch in adhesion and elasticity of C-cadherin | Q30482106 | ||
| Condensin regulates the stiffness of vertebrate centromeres | Q30487316 | ||
| DNA relaxation dynamics as a probe for the intracellular environment. | Q30488160 | ||
| Unfolding proteins by external forces and temperature: the importance of topology and energetics | Q30872914 | ||
| Solving the shugoshin puzzle | Q33345387 | ||
| HEAT repeats associated with condensins, cohesins, and other complexes involved in chromosome-related functions | Q33922394 | ||
| Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme | Q34000718 | ||
| Preferential binding of ATR protein to UV-damaged DNA. | Q34067234 | ||
| Molecular dynamics simulations in biology | Q34239646 | ||
| Transcriptional co-activator p75 binds and tethers the Myc-interacting protein JPO2 to chromatin | Q34532019 | ||
| Mechanotransduction: touch and feel at the molecular level as modeled in Caenorhabditis elegans | Q34705398 | ||
| Cell and molecular mechanics of biological materials | Q35573490 | ||
| Site-directed mutagenesis of amino acid residues of protein phosphatase 1 involved in catalysis and inhibitor binding | Q36101145 | ||
| Karyopherin flexibility in nucleocytoplasmic transport | Q36432992 | ||
| Mechanotransduction involving multimodular proteins: converting force into biochemical signals | Q36475420 | ||
| Molecular mechanisms of cellular mechanics | Q36560235 | ||
| Mechanosensitive channel of large conductance. | Q36756919 | ||
| Single-molecule experiments in vitro and in silico | Q36831515 | ||
| PP2A holoenzyme assembly: in cauda venenum (the sting is in the tail). | Q37091364 | ||
| Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus | Q37386626 | ||
| Cell fate regulation by coupling mechanical cycles to biochemical signaling pathways | Q37393132 | ||
| Forces and torques in the nucleus: chromatin under mechanical constraints | Q37398648 | ||
| From promiscuity to precision: protein phosphatases get a makeover | Q37414833 | ||
| A mechanical basis for chromosome function | Q37494079 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 2467-2472 | |
| P577 | publication date | 2010-01-25 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | PR65, the HEAT-repeat scaffold of phosphatase PP2A, is an elastic connector that links force and catalysis | |
| P478 | volume | 107 |
| Q99710798 | ATR is essential for preservation of cell mechanics and nuclear integrity during interstitial migration |
| Q34001058 | ATR mediates a checkpoint at the nuclear envelope in response to mechanical stress |
| Q26747245 | ATR-mediated regulation of nuclear and cellular plasticity |
| Q29029185 | An Unusual Hydrophobic Core Confers Extreme Flexibility to HEAT Repeat Proteins |
| Q35664788 | Chromosomes Progress to Metaphase in Multiple Discrete Steps via Global Compaction/Expansion Cycles. |
| Q35550779 | Cohesin, condensin, and the intramolecular centromere loop together generate the mitotic chromatin spring. |
| Q34635963 | Complex energy landscape of a giant repeat protein |
| Q35008479 | Control of mTORC1 signaling by the Opitz syndrome protein MID1. |
| Q89871685 | Direct Activation of Protein Phosphatase 2A (PP2A) by Tricyclic Sulfonamides Ameliorates Alzheimer's Disease Pathogenesis in Cell and Animal Models |
| Q34557983 | Effects of ligand binding on the mechanical properties of ankyrin repeat protein gankyrin |
| Q88596167 | Folding cooperativity and allosteric function in the tandem-repeat protein class |
| Q34039121 | Functional and genomic analyses of alpha-solenoid proteins |
| Q39311049 | Genome organization during the cell cycle: unity in division. |
| Q35056067 | HD CAG-correlated gene expression changes support a simple dominant gain of function |
| Q45299796 | Huntingtin is a scaffolding protein in the ATM oxidative DNA damage response complex. |
| Q36839701 | Huntingtin's spherical solenoid structure enables polyglutamine tract-dependent modulation of its structure and function |
| Q90197696 | Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors |
| Q30353134 | Is Huntingtin Dispensable in the Adult Brain? |
| Q27327234 | Mechanisms of the scaffold subunit in facilitating protein phosphatase 2A methylation |
| Q36476907 | Meiosis I chromosome segregation is established through regulation of microtubule-kinetochore interactions. |
| Q38126721 | Meiosis I: when chromosomes undergo extreme makeover. |
| Q33929264 | Mesoscale spatial patterning in the Escherichia coli Min system: reaction-diffusion versus mechanical communication. |
| Q35863030 | Mitotic spindle form and function |
| Q42236307 | Mroh1, a lysosomal regulator localized by WASH-generated actin |
| Q34829422 | Mutant huntingtin causes defective actin remodeling during stress: defining a new role for transglutaminase 2 in neurodegenerative disease |
| Q30425105 | One small step for Mot1; one giant leap for other Swi2/Snf2 enzymes? |
| Q40344179 | Phylogenetic Diversity of NTT Nucleotide Transport Proteins in Free-Living and Parasitic Bacteria and Eukaryotes |
| Q38374920 | Post-Translational Modifications (PTMs), Identified on Endogenous Huntingtin, Cluster within Proteolytic Domains between HEAT Repeats |
| Q91843539 | Protein phosphatase 2A Aα regulates Aβ protein expression and stability |
| Q42183206 | Prying open single GroES ring complexes by force reveals cooperativity across domains |
| Q46734062 | Questions and Assays |
| Q90198848 | Reduction of protein phosphatase 2A (PP2A) complexity reveals cellular functions and dephosphorylation motifs of the PP2A/B'δ holoenzyme |
| Q38358069 | Regulation of Ca(2+) transient by PP2A in normal and failing heart |
| Q28259286 | Rpn1 and Rpn2 coordinate ubiquitin processing factors at proteasome |
| Q34313327 | S-phase sensing of DNA-protein crosslinks triggers TopBP1-independent ATR activation and p53-mediated cell death by formaldehyde |
| Q34582276 | Sensor potency of the moonlighting enzyme-decorated cytoskeleton: the cytoskeleton as a metabolic sensor |
| Q27684630 | Structural and biochemical characterization of human PR70 in isolation and in complex with the scaffolding subunit of protein phosphatase 2A |
| Q28315106 | Structural and mechanistic insights into human splicing factor SF3b complex derived using an integrated approach guided by the cryo-EM density maps |
| Q27675679 | Structural basis for cooperativity of CRM1 export complex formation |
| Q33914715 | Structural insights into NHEJ: building up an integrated picture of the dynamic DSB repair super complex, one component and interaction at a time |
| Q33870839 | The DNA damage response kinases DNA-dependent protein kinase (DNA-PK) and ataxia telangiectasia mutated (ATM) Are stimulated by bulky adduct-containing DNA. |
| Q28081821 | The DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosis |
| Q37969749 | The biological function of the Huntingtin protein and its relevance to Huntington's Disease pathology |
| Q38257019 | The replication checkpoint protects fork stability by releasing transcribed genes from nuclear pores. |
| Q47436859 | Therapeutic Targeting of PP2A. |
| Q52624746 | Using FlAsH to probe conformational changes in a large HEAT repeat protein. |
| Q24316303 | pARIS-htt: an optimised expression platform to study huntingtin reveals functional domains required for vesicular trafficking |
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