Mroh1, a lysosomal regulator localized by WASH-generated actin

scientific article published on 19 April 2017

Mroh1, a lysosomal regulator localized by WASH-generated actin is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1242/JCS.197210
P932PMC publication ID5450189
P698PubMed publication ID28424231

P50authorJason S KingQ54954915
Peter A ThomasonQ59682024
Robert H InsallQ37838436
P2093author name stringJason S King
Peter A Thomason
P2860cites workThe structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifsQ22001450
NIH Image to ImageJ: 25 years of image analysisQ23319322
Recruitment of the endosomal WASH complex is mediated by the extended 'tail' of Fam21 binding to the retromer protein Vps35Q24296505
The Arp2/3 activator WASH regulates α5β1-integrin-mediated invasive migrationQ24298177
WASH and the Arp2/3 complex regulate endosome shape and traffickingQ24300504
The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamicsQ24301952
Endosomal recruitment of the WASH complex: active sequences and mutations impairing interaction with the retromerQ24309624
WASH and WAVE actin regulators of the Wiskott-Aldrich syndrome protein (WASP) family are controlled by analogous structurally related complexesQ24314791
A FAM21-containing WASH complex regulates retromer-dependent sortingQ24318406
The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complexQ24318446
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Drosophila WASH is required for integrin-mediated cell adhesion, cell motility and lysosomal neutralization.Q39155569
Cyclical action of the WASH complex: FAM21 and capping protein drive WASH recycling, not initial recruitmentQ39201487
Evolutionary conservation of the WASH complex, an actin polymerization machine involved in endosomal fissionQ39846943
Identifying specific protein interaction partners using quantitative mass spectrometry and bead proteomesQ41783290
Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathwayQ56990540
Mucolipin controls lysosome exocytosis in DictyosteliumQ58450899
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Function and regulation of the endosomal fusion and fission machineriesQ27015677
Actin polymerization controls the organization of WASH domains at the surface of endosomesQ27300446
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The XMAP215 family drives microtubule polymerization using a structurally diverse TOG arrayQ27684463
The amino-terminal domain of the B subunit of vacuolar H+-ATPase contains a filamentous actin binding siteQ28142113
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Candidate testis-determining gene, Maestro (Mro), encodes a novel HEAT repeat proteinQ28506511
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PR65, the HEAT-repeat scaffold of phosphatase PP2A, is an elastic connector that links force and catalysisQ30493200
SCAR/WAVE is activated at mitosis and drives myosin-independent cytokinesisQ30494901
Sequence-dependent sorting of recycling proteins by actin-stabilized endosomal microdomains.Q30498760
PIP₃-dependent macropinocytosis is incompatible with chemotaxisQ30572075
A unique HEAT repeat-containing protein SHOOT GRAVITROPISM6 is involved in vacuolar membrane dynamics in gravity-sensing cells of Arabidopsis inflorescence stem.Q30575809
A plasma membrane template for macropinocytic cupsQ30831841
4.4 Å Resolution Cryo-EM structure of human mTOR Complex 1Q30833513
Lysosomal physiologyQ34462083
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Actin polymerization driven by WASH causes V-ATPase retrieval and vesicle neutralization before exocytosisQ35018231
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Multiple repeat elements within the FAM21 tail link the WASH actin regulatory complex to the retromerQ36030504
Trafficking defects in WASH-knockout fibroblasts originate from collapsed endosomal and lysosomal networksQ36161695
WASH is required for lysosomal recycling and efficient autophagic and phagocytic digestionQ37131503
The V-type H+-ATPase in vesicular trafficking: targeting, regulation and functionQ37176811
WASH drives early recycling from macropinosomes and phagosomes to maintain surface phagocytic receptorsQ37323063
Vacuolar H(+)-ATPases: intra- and intermolecular interactionsQ37884723
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P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue10
P407language of work or nameEnglishQ1860
P304page(s)1785-1795
P577publication date2017-04-19
P1433published inJournal of Cell ScienceQ1524177
P1476titleMroh1, a lysosomal regulator localized by WASH-generated actin
P478volume130

Reverse relations

cites work (P2860)
Q91681895High-throughput Measurement of Dictyostelium discoideum Macropinocytosis by Flow Cytometry
Q58450109Myosin VI and branched actin filaments mediate membrane constriction and fission of melanosomal tubule carriers
Q47345045WASP family proteins and formins compete in pseudopod- and bleb-based migration.

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